Structure-function correlations in oxygen activating non-heme iron enzymes.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Chemical Communications

• Publication date

  2005-11-28

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1039/B510233MPMID 16317455
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Bleomycins: towards better therapeutics

  2005cited by this paper
• The 2-His-1-carboxylate facial triad: a versatile platform for dioxygen activation by mononuclear non-heme iron(II) enzymes

  2005cited by this paper
• CD and MCD studies of the non-heme ferrous active site in (4-hydroxyphenyl)pyruvate dioxygenase: correlation between oxygen activation in the extradiol and alpha-KG-dependent dioxygenases.

  2004cited by this paper
• Direct detection of oxygen intermediates in the non-heme Fe enzyme taurine/alpha-ketoglutarate dioxygenase.

  2004cited by this paper
• Fe(II)/α-Ketoglutarate-Dependent Hydroxylases and Related Enzymes

  2004cited by this paper
• EXAFS spectroscopic evidence for an Fe=O unit in the Fe(IV) intermediate observed during oxygen activation by taurine:alpha-ketoglutarate dioxygenase.

  2004cited by this paper
• Spectroscopic and quantum chemical characterization of the electronic structure and bonding in a non-heme FeIV[double bond]O complex.

  2004cited by this paper
• Spectroscopic and Quantum Chemical Characterization of the Electronic Structure and Bonding in a Non-Heme FeIVO Complex

  2004cited by this paper
• Oxygen sensing by HIF hydroxylases

  2004cited by this paper
• Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins.

  2004cited by this paper
• FeII/alpha-ketoglutarate-dependent hydroxylases and related enzymes.

  2004cited by this paper
• Spectroscopic Characterization of an FeIV Intermediate Generated by Reaction of XO− (X = Cl, Br) with an FeII Complex Bearing a Pentadentate Non-Porphyrinic Ligand − Hydroxylation and Epoxidation Activity

  2004cited by this paper
• Comparison between the geometric and electronic structures and reactivities of [FeNO]7 and [FeO2]8 complexes: a density functional theory study.

  2004cited by this paper
• Density-functional investigation on the mechanism of H-atom abstraction by lipoxygenase

  2003cited by this paper
• Crystal Structure of Naphthalene Dioxygenase: Side-on Binding of Dioxygen to Iron

  2003cited by this paper
• Spectroscopic and kinetic studies of PKU-inducing mutants of phenylalanine hydroxylase: Arg158Gln and Glu280Lys.

  2003cited by this paper
• Crystallographic and spectroscopic characterization of a nonheme Fe(IV)-O complex.

  2003cited by this paper
• An FeIVO complex of a tetradentate tripodal nonheme ligand

  2003cited by this paper
• Spectroscopic studies of the interaction of ferrous bleomycin with DNA.

  2003cited by this paper
• Structure of Factor-inhibiting Hypoxia-inducible Factor (HIF) Reveals Mechanism of Oxidative Modification of HIF-1α*

  2003cited by this paper
• The first direct characterization of a high-valent iron intermediate in the reaction of an alpha-ketoglutarate-dependent dioxygenase: a high-spin FeIV complex in taurine/alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli.

  2003cited by this paper
• (4-Hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis: the basis for ordered substrate addition.

  2003cited by this paper
• Non-heme iron enzymes: Contrasts to heme catalysis

  2003cited by this paper
• Spectroscopic and electronic structure studies of 2,3-dihydroxybiphenyl 1,2-dioxygenase: O2 reactivity of the non-heme ferrous site in extradiol dioxygenases.

  2003cited by this paper
• Definitive evidence for monoanionic binding of 2,3-dihydroxybiphenyl to 2,3-dihydroxybiphenyl 1,2-dioxygenase from UV resonance Raman spectroscopy, UV/Vis absorption spectroscopy, and crystallography.

  2002cited by this paper
• Electronic structure and reactivity of low-spin Fe(III)-hydroperoxo complexes: comparison to activated bleomycin.

  2002cited by this paper
• Spectroscopic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: molecular mechanism and CO(2) activation in the biosynthesis of ethylene.

  2002cited by this paper
• Identification and analysis of a bottleneck in PCB biodegradation

  2002cited by this paper
• Spectroscopic and electronic structure studies of protocatechuate 3,4-dioxygenase: nature of tyrosinate-Fe(III) bonds and their contribution to reactivity.

  2002cited by this paper
• X-ray absorption spectroscopic investigation of the resting ferrous and cosubstrate-bound active sites of phenylalanine hydroxylase.

  2002cited by this paper
• X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates.

  2002cited by this paper
• Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family*

  2002cited by this paper
• Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

  2002cited by this paper
• AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli

  2002cited by this paper
• Spectroscopic studies of substrate interactions with clavaminate synthase 2, a multifunctional alpha-KG-dependent non-heme iron enzyme: correlation with mechanisms and reactivities.

  2001cited by this paper
• Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.

  2001cited by this paper
• Crystal structures of substrate free and complex forms of reactivated BphC, an extradiol type ring-cleavage dioxygenase.

  2001cited by this paper
• Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS).

  2001cited by this paper
• One motif — many different reactions

  2000cited by this paper
• Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase

  2000cited by this paper
• Crystal structure of human homogentisate dioxygenase

  2000cited by this paper
• Structure of Acinetobacter strain ADP1 protocatechuate 3, 4-dioxygenase at 2.2 A resolution: implications for the mechanism of an intradiol dioxygenase.

  2000cited by this paper
• Mononuclear (nitrido)iron(V) and (oxo)iron(IV) complexes via photolysis of [(cyclam-acetato)FeIII(N3)]+ and ozonolysis of [(cyclam-acetato)FeIII(O3SCF3)]+ in water/acetone mixtures.

  2000cited by this paper
• Bleomycin: new perspectives on the mechanism of action.

  2000cited by this paper
• Geometric and electronic structure/function correlations in non-heme iron enzymes.

  2000cited by this paper
• Nature of Activated Bleomycin

  2000cited by this paper
• Biosynthesis of the Vancomycin Group of Antibiotics: Involvement of an Unusual Dioxygenase in the Pathway to (S)-4-Hydroxyphenylglycine

  2000cited by this paper
• Electronic Structure of Activated Bleomycin: Oxygen Intermediates in Heme versus Non-Heme Iron

  2000cited by this paper
• Missense mutations in the phenylalanine hydroxylase gene (PAH) can cause accelerated proteolytic turnover of PAH enzyme: A mechanism underlying phenylketonuria

  1999cited by this paper
• Nucleic Acid recognition by metal complexes of bleomycin.

  1999cited by this paper
• Lipoxygenase inhibitors as potential cancer chemopreventives.

  1999cited by this paper
• Role of the nonheme Fe(II) center in the biosynthesis of the plant hormone ethylene.

  1999cited by this paper
• Benzene-Induced Uncoupling of Naphthalene Dioxygenase Activity and Enzyme Inactivation by Production of Hydrogen Peroxide

  1999cited by this paper
• Circular Dichroism and Magnetic Circular Dichroism Spectroscopy of the Catalytically Competent Ferrous Active Site of Phenylalanine Hydroxylase and Its Interaction with Pterin Cofactor

  1999cited by this paper
• Stopped-flow kinetic analysis of Escherichia coli taurine/alpha-ketoglutarate dioxygenase: interactions with alpha-ketoglutarate, taurine, and oxygen.

  1999cited by this paper
• Crystal structure of Pseudomonas fluorescens 4-hydroxyphenylpyruvate dioxygenase: an enzyme involved in the tyrosine degradation pathway.

  1999cited by this paper
• NMR STUDIES OF CO.DEGLYCOBLEOMYCIN A2 GREEN AND ITS COMPLEX WITH D(CCAGGCCTGG)

  1998cited by this paper
• Cleavage of Nucleic Acids by Bleomycin.

  1998cited by this paper
• Spectroscopic Investigation of the Metal Ligation and Reactivity of the Ferrous Active Sites of Bleomycin and Bleomycin Derivatives

  1998cited by this paper
• Detailed Spectroscopic and Theoretical Studies on [Fe(EDTA)(O2)]3-: Electronic Structure of the Side-on Ferric−Peroxide Bond and Its Relevance to Reactivity

  1998cited by this paper
• The axial tyrosinate Fe3+ ligand in protocatechuate 3,4-dioxygenase influences substrate binding and product release: evidence for new reaction cycle intermediates.

  1998cited by this paper
• Structure of an aromatic-ring-hydroxylating dioxygenase-naphthalene 1,2-dioxygenase.

  1998cited by this paper
• Circular Dichroism and Magnetic Circular Dichroism Spectroscopic Studies of the Non-Heme Ferrous Active Site in Clavaminate Synthase and Its Interaction with α-Ketoglutarate Cosubstrate

  1998cited by this paper
• Substrate Binding to the α-Ketoglutarate-Dependent Non-Heme Iron Enzyme Clavaminate Synthase 2: Coupling Mechanism of Oxidative Decarboxylation and Hydroxylation

  1998cited by this paper
• Magnetic Circular Dichroism Spectroscopic Studies of Mononuclear Non-Heme Ferrous Model Complexes. Correlation of Excited- and Ground-State Electronic Structure with Geometry

  1998cited by this paper
• Structure of a cephalosporin synthase

  1998cited by this paper
• Crystal structure and resonance Raman studies of protocatechuate 3,4-dioxygenase complexed with 3,4-dihydroxyphenylacetate.

  1997cited by this paper
• Ethylene biosynthesis: The role of 1‐aminocyclopropane‐1‐carboxylate (ACC) oxidase, and its possible evolutionary origin

  1997cited by this paper
• Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.

  1997cited by this paper
• Spectroscopic Characterization of the Catalytically Competent Ferrous Site of the Resting, Activated, and Substrate-Bound Forms of Phenylalanine Hydroxylase

  1997cited by this paper
• Structures of competitive inhibitor complexes of protocatechuate 3,4-dioxygenase: multiple exogenous ligand binding orientations within the active site.

  1997cited by this paper
• Crystal structures of substrate and substrate analog complexes of protocatechuate 3,4-dioxygenase: endogenous Fe3+ ligand displacement in response to substrate binding.

  1997cited by this paper
• New insights from spectroscopy into the structure/function relationships of lipoxygenases.

  1997cited by this paper
• The 2-His-1-carboxylate facial triad--an emerging structural motif in mononuclear non-heme iron(II) enzymes.

  1997cited by this paper
• Structure of isopenicillinN synthase complexed with substrate and the mechanism ofpenicillin formation

  1997cited by this paper
• Pterin-Dependent Amino Acid Hydroxylases.

  1996cited by this paper
• BLEOMYCINS : A STRUCTURAL MODEL FOR SPECIFICITY, BINDING, AND DOUBLE STRAND CLEAVAGE

  1996cited by this paper
• Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution.

  1996cited by this paper
• Lipoxygenase reaction mechanism: demonstration that hydrogen abstraction from substrate precedes dioxygen binding during catalytic turnover.

  1996cited by this paper
• Arene hydroxylases: metalloenzymes catalysing dioxygenation of aromatic compounds☆

  1996cited by this paper
• Structural and Functional Aspects of Metal Sites in Biology.

  1996cited by this paper
• A single monomeric iron center in clavaminate synthase catalyzes three nonsuccessive oxidative transformations.

  1996cited by this paper
• Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes

  1995cited by this paper
• Identification, cloning, sequencing, and overexpression of the gene encoding proclavaminate amidino hydrolase and characterization of protein function in clavulanic acid biosynthesis

  1995cited by this paper
• Near-infrared circular dichroism and magnetic circular dichroism and x-ray absorption spectral comparison of the non-heme ferrous active sites of plant and mammalian 15-lipoxygenases

  1995cited by this paper
• Iron Coordination of Activated Bleomycin Probed by Q- and X-Band ENDOR: Hyperfine Coupling to Activated 17O Oxygen, 14N, and Exchangeable 1H

  1995cited by this paper
• Spectroscopic and Kinetic Properties of Unphosphorylated Rat Hepatic Phenylalanine Hydroxylase Expressed in Escherichia coli

  1995cited by this paper
• Saturation Magnetization Magnetic Circular Dichroism Spectroscopy of Systems with Positive Zero-Field Splittings: Application to FeSiF6.cntdot.6H2O

  1995cited by this paper
• Spectroscopic Definition of the Geometric and Electronic Structure of the Non-Heme Iron Active Site in Iron(II) Bleomycin: Correlation with Oxygen Reactivity

  1995cited by this paper
• Determination of the Geometric and Electronic Structure of Activated Bleomycin Using X-ray Absorption Spectroscopy

  1995cited by this paper
• Oxygen isotope effect on activated bleomycin stability

  1995cited by this paper
• Magnetic circular dichroism spectroscopy as a probe of the geometric and electronic structure of non-heme ferrous enzymes

  1995cited by this paper
• Crystal Structure of the Biphenyl-Cleaving Extradiol Dioxygenase from a PCB-Degrading Pseudomonad

  1995cited by this paper
• 12-Lipoxygenases and 12(S)-HETE: role in cancer metastasis

  1994cited by this paper
• Regulation of rat liver phenylalanine hydroxylase. III. Control of catalysis by (6R)-tetrahydrobiopterin and phenylalanine.

  1994cited by this paper
• Structure of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa at 2.15 A resolution.

  1994cited by this paper
• Magnetic circular dichroism studies of exogenous ligand and substrate binding to the non-heme ferrous active site in phthalate dioxygenase.

  1994cited by this paper
• X-ray spectroscopy of the iron site in soybean lipoxygenase-1: changes in coordination upon oxidation or addition of methanol.

  1994cited by this paper
• Electrospray Mass Spectrometry of Iron Bleomycin: Demonstration That Activated Bleomycin Is a Ferric Peroxide Complex

  1994cited by this paper
• 5-Lipoxygenase.

  1994cited by this paper

• Photoactive Fe(III) pyclen complexes for light-driven aerobic oxidation of p-xylene.

  2026cites this paper
• Spectroscopy and crystallography define carotenoid oxygenases as a new subclass of mononuclear non-heme FeII enzymes

  2025cites this paper
• Magnetospectroscopic Studies of a Series of Fe(II) Scorpionate Complexes: Assessing the Relationship between Halide Identity and Zero-Field Splitting

  2025cites this paper
• The Role of the Unusual 2-Tyr-1-carboxylate Nonheme Iron Motif in the Mechanism of N,N-Dimethylformamidase

  2025cites this paper
• The reaction mechanism of intramolecular C-C coupling catalyzed by the non-heme deoxypodophyllotoxin synthase.

  2025cites this paper
• Spectroscopic definition of ferrous active sites in non-heme iron enzymes.

  2024cites this paper
• Spectroscopic and Theoretical Investigation of High-Spin Square-Planar and Trigonal Fe(II) Complexes Supported by Fluorinated Alkoxides.

  2024cites this paper
• Non-Noble Metal Aromatic Oxidation Catalysis: From Metalloenzymes to Synthetic Complexes

  2023cites this paper
• Preparation of carotenoid cleavage dioxygenases for X-ray crystallography.

  2022cites this paper
• Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions

  2022cites this paper
• Characterization and genomic analysis of a novel halovirus infecting Chromohalobacter beijerinckii

  2022cites this paper
• Thermodynamics of iron, tetrahydrobiopterin, and phenylalanine binding to phenylalanine hydroxylase from Chromobacterium violaceum.

  2022cites this paper
• Substrate-Specific Coupling of O2 Activation to Hydroxylations of Aromatic Compounds by Rieske Non-heme Iron Dioxygenases

  2022cites this paper
• Structural Insight into the Catalytic Mechanism of the Endoperoxide Synthase FtmOx1.

  2021cites this paper
• Functional role of residues involved in substrate binding of human 4-hydroxyphenylpyruvate dioxygenase.

  2021cites this paper
• Engineering the Oxidative Potency of Non-Heme Iron(IV) Oxo Complexes in Water for C-H Oxidation by a cis Donor and Variation of the Second Coordination Sphere.

  2021cites this paper
• Catalytic Selective Oxidation of Primary and Secondary Alcohols Using Nonheme [Iron(III)(Pyridine‐Containing Ligand)] Complexes

  2020cites this paper
• O2-binding to all 3d-, 4d, and 5d-transition metals from coupled-cluster theory.

  2020cites this paper
• Eccentricities in Spectroscopy and Reactivity of Non‐Heme Metal Intermediates Contained in Bispidine Scaffolds

  2020cites this paper
• Conformational Dynamics Underlies Different Functions of Human KDM7 Histone Demethylases.

  2019cites this paper
• Evidence for distinct rate-limiting steps in the cleavage of alkenes by carotenoid cleavage dioxygenases

  2019cites this paper
• Structure of L509V CAO1 - growth condition 2

  2019cites this paper
• Alkene‐Cleaving Carotenoid Cleavage Dioxygenases

  2019cites this paper
• Magnetic circular dichroism spectra of transition metal complexes calculated from restricted active space wavefunctions.

  2019cites this paper
• Catalysis by the Non-Heme Iron(II) Histone Demethylase PHF8 Involves Iron Center Rearrangement and Conformational Modulation of Substrate Orientation

  2019cites this paper
• Spectroscopic and mechanistic investigation of the enzyme mercaptopropionic acid dioxygenase (MDO), the role of the conserved outer-sphere 'catalytic triad' in directing promiscuous substrate-specificity

  2018influential citation
• Deciphering the mechanism of O2 reduction with electronically tunable non-heme iron enzyme model complexes

  2018cites this paper
• Investigations on the role of a solvent tunnel in the α-ketoglutarate dependent oxygenase factor inhibiting HIF (FIH).

  2018cites this paper
• A Mixed-Valence Fluorido-Bridged FeIIFeIII Complex.

  2017cites this paper
• Synthesis and structural characterization of a hemiacetal and aldehyde bound diiron(III) complex with two different coordination numbers: A product by oxidative cleavage of carbon nitrogen single bond

  2017cites this paper
• Iron(II) Complexes of a Hemilabile SNS Amido Ligand: Synthesis, Characterization, and Reactivity.

  2017cites this paper
• Magnetic circular dichroism of UCl6- in the ligand-to-metal charge-transfer spectral region.

  2017cites this paper
• Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants

  2017cites this paper
• Structure/function correlations over binuclear non-heme iron active sites

  2016cites this paper
• Magnetic circular dichroism studies of iron(ii) binding to human calprotectin

  2016cites this paper
• Electrode instead of catalyst and enzyme. A greener protocol for the synthesis of new 2-hydroxyacetamide derivatives containing a γ-lactone ring

  2016cites this paper
• Inhibition and Cofactor Targeting of Hypoxia-Sensing Proteins

  2015cites this paper
• A Series of Dinuclear Complexes with a Flexible Naphthalene‐Spacer and MOM‐Cleavage by Pre‐coordinated Lewis Acids

  2015cites this paper
• High-Valent Iron in Biomimetic Alkane Oxidation Catalysis

  2015cites this paper
• Thiol Dioxygenases: An Investigation Into The Mechanisms Of Cysteine Dioxygenase And 3-mercaptopropionic Acid Dioxygenase

  2015cites this paper
• Biochemical, kinetic and spectroscopic characterizations of non-heme iron oxygenase enzymes

  2015cites this paper
• Dearomatization Reactions Using Phthaloyl Peroxide.

  2015cites this paper
• High Valent FeIV Chemistry in Sustainable Oxidation Catalysis

  2015cites this paper
• Utilization of Dioxygen by Carotenoid Cleavage Oxygenases*♦

  2015cites this paper
• Iron(III) Complexes of Cysteine and Methyl Glycine Aminophenol Ligands

  2015cites this paper
• Oxygen sensing strategies in mammals and bacteria.

  2014cites this paper
• 3-Ketosteroid 9α-hydroxylase enzymes: Rieske non-heme monooxygenases essential for bacterial steroid degradation

  2014cites this paper
• Flexible binding of PNP pincer ligands to monomeric iron complexes.

  2014cites this paper
• Spectroscopic studies of the mononuclear non-heme Fe(II) enzyme FIH: second-sphere contributions to reactivity.

  2013cites this paper
• A Mononuclear Nonheme Iron(III)-Peroxo Complex Binding Redox-Inactive Metal Ions.

  2013cites this paper
• Sulfide Oxidation by O2: Synthesis, Structure and Reactivity of Novel Sulfide-Incorporated Fe(II) Bis(imino)pyridine Complexes.

  2013cites this paper
• Structure and function of atypically coordinated enzymatic mononuclear non-heme-Fe(II) centers

  2013cites this paper
• Comparison of high-spin and low-spin nonheme Fe(III)-OOH complexes in O-O bond homolysis and H-atom abstraction reactivities.

  2013cites this paper
• Oxygen Atom Transfer

  2013cites this paper
• Oxygen activation by homoprotocatechuate 2,3-dioxygenase: a QM/MM study reveals the key intermediates in the activation cycle

  2013cites this paper
• The effect of varying carboxylate ligation on the electronic environment of N2O(x) (x = 1-3) nonheme iron: a DFT analysis.

  2012cites this paper
• Structural and computational enzymology: bringing experiments and computations together.

  2012cites this paper
• Investigating the oxidation of alkenes by non-heme iron enzyme mimics.

  2012cites this paper
• l-Proline-derived ligands to mimic the ‘2-His-1-carboxylate’ triad of the non-haem iron oxidase active site

  2012cites this paper
• The 3His Triad in Dke1: Comparisons to the Classical Facial Triad

  2011cites this paper
• Spectroscopic and computational studies of α-keto acid binding to Dke1: understanding the role of the facial triad and the reactivity of β-diketones.

  2011cites this paper
• Structural and mechanistic comparisons of the metal-binding members of the vicinal oxygen chelate (VOC) superfamily.

  2011cites this paper
• X-ray absorption spectroscopy structural investigation of early intermediates in the mechanism of DNA repair by human ABH2.

  2011cites this paper
• Metalloproteins from Hyperthermophiles

  2011cites this paper
• Biomimetic Single-Site Heterogeneous Catalysts: Design Strategies and Catalytic Potential

  2011cites this paper
• Design strategies for engineering selectivity in bio-inspired heterogeneous catalysts

  2011cites this paper
• Activation of α-keto acid-dependent dioxygenases: application of an {FeNO}7/{FeO2}8 methodology for characterizing the initial steps of O2 activation.

  2011cites this paper
• XAS Structural Investigation of Early Intermediates in the Mechanism of DNA Repair by Human ABH2

  2011cites this paper
• The three-his triad in Dke1: comparisons to the classical facial triad.

  2010cites this paper
• Iron(III) complexes of tridentate N3 ligands as models for catechol dioxygenases: Stereoelectronic effects of pyrazole coordination

  2010cites this paper
• Dioxygen activation responsible for oxidation of aliphatic and aromatic hydrocarbon compounds: current state and variants

  2010cites this paper
• Design and synthesis of a tetradentate '3-amine-1-carboxylate' ligand to mimic the metal binding environment at the non-heme iron(II) oxidase active site.

  2010cites this paper
• DFT study of a model system for the dealkylation step catalyzed by AlkB

  2010cites this paper
• Peroxo and oxo intermediates in mononuclear nonheme iron enzymes and related active sites.

  2009cites this paper
• An iron(II) complex with a N3S2 thioether ligand in the generation of an iron(IV)-oxo complex and its reactivity in olefin epoxidation

  2009cites this paper
• Iron(III) complexes of tripodal monophenolate ligands as models for non-heme catechol dioxygenase enzymes: correlation of dioxygenase activity with ligand stereoelectronic properties.

  2009cites this paper
• Spectroscopy and kinetics of wild-type and mutant tyrosine hydroxylase: mechanistic insight into O2 activation.

  2009cites this paper
• Water as an oxygen source in the generation of mononuclear nonheme iron(IV) oxo complexes.

  2009cites this paper
• Demonstration That CobG, the Monooxygenase Associated with the Ring Contraction Process of the Aerobic Cobalamin (Vitamin B12) Biosynthetic Pathway, Contains an Fe-S Center and a Mononuclear Non-heme Iron Center*

  2009cites this paper
• Mechanistic studies on oxidation of hydrogen peroxide by an oxo-bridged diiron complex in aqueous acidic media.

  2008cites this paper
• Resonance Raman characterization of the peroxo and hydroperoxo intermediates in cytochrome P450.

  2008cites this paper
• Near-IR MCD of the nonheme ferrous active site in naphthalene 1,2-dioxygenase: correlation to crystallography and structural insight into the mechanism of Rieske dioxygenases.

  2008cites this paper
• Mechanistic implications of the active species involved in the oxidation of hydrocarbons by iron complexes of pyrazine-2-carboxylic acid.

  2008cites this paper
• Evidence That Two Enzyme-derived Histidine Ligands Are Sufficient for Iron Binding and Catalysis by Factor Inhibiting HIF (FIH)*

  2008cites this paper
• Mononuclear non-heme iron enzymes with the 2-His-1-carboxylate facial triad: recent developments in enzymology and modeling studies.

  2008cites this paper
• Spectroscopic and electronic structure study of the enzyme-substrate complex of intradiol dioxygenases: substrate activation by a high-spin ferric non-heme iron site.

  2007cites this paper
• CD and MCD of CytC3 and taurine dioxygenase: role of the facial triad in alpha-KG-dependent oxygenases.

  2007cites this paper
• Design of artificial metallonucleases with oxidative mechanism

  2007cites this paper
• Experimental and theoretical evidence for nonheme iron(III) alkylperoxo species as sluggish oxidants in oxygenation reactions.

  2007cites this paper
• Cysteine dioxygenase: structure and mechanism.

  2007cites this paper
• Fe L-edge X-ray absorption spectroscopy of low-spin heme relative to non-heme Fe complexes: delocalization of Fe d-electrons into the porphyrin ligand.

  2007cites this paper
• Combined experimental and theoretical study on aromatic hydroxylation by mononuclear nonheme iron(IV)-oxo complexes.

  2007cites this paper
• Oxidative N-dealkylation reactions by oxoiron(IV) complexes of nonheme and heme ligands.

  2007cites this paper
• Kinetic and spectroscopic studies of N694C lipoxygenase: a probe of the substrate activation mechanism of a nonheme ferric enzyme.

  2007cites this paper
• Structure—Function Correlations in Oxygen Activating Non-heme Iron Enzymes

  2006cites this paper
• Differences in and Comparison of the Catalytic Properties of Heme and Non-Heme Enzymes with a Central Oxo–Iron Group†

  2006cites this paper
• Spectroscopic and electronic structure studies of the role of active site interactions in the decarboxylation reaction of alpha-keto acid-dependent dioxygenases.

  2006cites this paper
• Spectroscopic and electronic structure studies of aromatic electrophilic attack and hydrogen-atom abstraction by non-heme iron enzymes

  2006cites this paper
• Differences in and comparison of the catalytic properties of heme and non-heme enzymes with a central oxo-iron group.

  2006cites this paper