Direct and indirect association of the small GTPase ran with nuclear pore proteins and soluble transport factors: studies in Xenopus laevis egg extracts.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Molecular Biology of the Cell

• Publication date

  1996-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/MBC.7.9.1319PMID 8885229PMCID PMC275984
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nuclear protein import.

  1997cited by this paper
• Ran Binding Domains Promote the Interaction of Ran with p97/β-Karyopherin, Linking the Docking and Translocation Steps of Nuclear Import (*)

  1996cited by this paper
• The small nuclear GTPase Ran: How much does it run?

  1996cited by this paper
• The search for the primary function of the Ran GTPase continues.

  1996cited by this paper
• The C Terminus of the Nuclear RAN/TC4 GTPase Stabilizes the GDP-bound State and Mediates Interactions with RCC1, RAN-GAP, and HTF9A/RANBP1 (*)

  1995cited by this paper
• Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport.

  1995cited by this paper
• Differential Mitotic Phosphorylation of Proteins of the Nuclear Pore Complex (*)

  1995cited by this paper
• Co‐activation of RanGTPase and inhibition of GTP dissociation by Ran‐GTP binding protein RanBP1.

  1995cited by this paper
• Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import substrate at nuclear pore complexes.

  1995cited by this paper
• Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62

  1995cited by this paper
• GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import

  1995cited by this paper
• Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins.

  1995cited by this paper
• The Ran/TC4 GTPase-binding domain: identification by expression cloning and characterization of a conserved sequence motif.

  1995cited by this paper
• Mechanisms of nuclear protein import.

  1995cited by this paper
• Inhibition of transcription elongation by the VHL tumor suppressor protein

  1995cited by this paper
• Nup358, a Cytoplasmically Exposed Nucleoporin with Peptide Repeats, Ran-GTP Binding Sites, Zinc Fingers, a Cyclophilin A Homologous Domain, and a Leucine-rich Region (*)

  1995cited by this paper
• Protein export from the nucleus requires the GTPase Ran and GTP hydrolysis.

  1995cited by this paper
• The RCC1 Protein Interacts with Ran, RanBP1, hsc70, and a 340-kDa Protein in Xenopus Extracts (*)

  1995cited by this paper
• The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm.

  1995cited by this paper
• Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences.

  1995cited by this paper
• A giant nucleopore protein that binds Ran/TC4

  1995cited by this paper
• Distinct functions for the two importin subunits in nuclear protein import

  1995cited by this paper
• Sequence and characterization of cytoplasmic nuclear protein import factor p97

  1995cited by this paper
• Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope.

  1995cited by this paper
• Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins.

  1995cited by this paper
• In vivo evidence for involvement of a 58 kDa component of nuclear pore‐targeting complex in nuclear protein import.

  1995cited by this paper
• Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.

  1995cited by this paper
• Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing

  1995cited by this paper
• The nuclear pore complex.

  1995cited by this paper
• Nuclear pore complex assembly studied with a biochemical assay for annulate lamellae formation

  1995cited by this paper
• A small nuclear GTP-binding protein from tomato suppresses a Schizosaccharomyces pombe cell-cycle mutant.

  1994cited by this paper
• A family of proteins that stabilize the Ran/TC4 GTPase in its GTP-bound conformation.

  1994cited by this paper
• Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope

  1994cited by this paper
• Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression

  1994cited by this paper
• Tpr, a large coiled coil protein whose amino terminus is involved in activation of oncogenic kinases, is localized to the cytoplasmic surface of the nuclear pore complex

  1994cited by this paper
• Cytosolic factors in nuclear transport: what's importin?

  1994cited by this paper
• Pores for thought: nuclear pore complex proteins.

  1994cited by this paper
• A murine homolog of the yeast RNA1 gene is required for postimplantation development.

  1994cited by this paper
• Isolation of a protein that is essential for the first step of nuclear protein import.

  1994cited by this paper
• Purification of a Ran-interacting protein that is required for protein import into the nucleus.

  1994cited by this paper
• A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation.

  1994cited by this paper
• A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm.

  1993cited by this paper
• The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

  1993cited by this paper
• Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor [published erratum appears in J Cell Biol 1994 Jan;124(1-2):217]

  1993cited by this paper
• Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

  1993cited by this paper
• RCC1, a regulator of mitosis, is essential for DNA replication

  1992cited by this paper
• Structure and function of the nuclear pore complex.

  1992cited by this paper
• A complex of nuclear pore proteins required for pore function

  1991cited by this paper
• Systems for the study of nuclear assembly, DNA replication, and nuclear breakdown in Xenopus laevis egg extracts.

  1991cited by this paper
• Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide.

  1991cited by this paper
• Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase.

  1991cited by this paper
• Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors

  1990cited by this paper
• Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line

  1990cited by this paper
• CENP-B: a major human centromere protein located beneath the kinetochore

  1990cited by this paper
• Reconstitution of biochemically altered nuclear pores: transport can be eliminated and restored.

  1990cited by this paper
• Nuclear reconstitution in vitro: stages of assembly around protein-free DNA.

  1987cited by this paper
• Identification and characterization of a nuclear pore complex protein

  1986cited by this paper
• Localization of gold in biological tissue

  1981cited by this paper

• Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration

  2023cites this paper
• Nuclear pore complexes — a doorway to neural injury in neurodegeneration

  2022cites this paper
• Fishing forward and reverse: Advances in zebrafish phenomics.

  2018cites this paper
• The Power of Xenopus Egg Extract for Reconstitution of Centromere and Kinetochore Function.

  2017cites this paper
• Release of condensin from mitotic chromosomes requires the Ran-GTP gradient in the reorganized nucleus

  2017cites this paper
• Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner

  2015cites this paper
• Genome-wide identification of heat shock proteins (Hsps) and Hsp interactors in rice: Hsp70s as a case study

  2014cites this paper
• Regulation of Hsf4b nuclear translocation and transcription activity by phosphorylation at threonine 472 (739.2)

  2014cites this paper
• Hsc70 Contributes to Cancer Cell Survival by Preventing Rab1A Degradation under Stress Conditions

  2014influential citation
• Analysis of CRM1- and Nup214- dependent nuclear export of proteins

  2012cites this paper
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  2012cites this paper
• Nup358 interacts with APC and plays a role in cell polarization

  2009cites this paper
• Acting out of character: regulatory roles of nuclear pore complex proteins.

  2009cites this paper
• Transportin regulates major mitotic assembly events: from spindle to nuclear pore assembly.

  2009cites this paper
• A New Role for Nuclear Transport Factor 2 and Ran: Nuclear Import of CapG

  2008cites this paper
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  2008cites this paper
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  2007cites this paper
• Analysis of the functional role of nucleoporin Nup214 in nuclear transport and other cellular processes

  2007cites this paper
• Nuclear envelope breakdown is coordinated by both Nup358/RanBP2 and Nup153, two nucleoporins with zinc finger modules.

  2005cites this paper
• Versatility at the nuclear pore complex: lessons learned from the nucleoporin Nup153

  2005cites this paper
• The homologous putative GTPases Grn1p from fission yeast and the human GNL3L are required for growth and play a role in processing of nucleolar pre-rRNA.

  2005cites this paper
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  2005cites this paper
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  2004cites this paper
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  2003cites this paper
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  2003cites this paper
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  2003cites this paper
• Ran binds to chromatin by two distinct mechanisms.

  2002cites this paper
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  2002cites this paper
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  2001cites this paper
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  2001cites this paper
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  2001cites this paper
• Targeting of Ran: variation on a common theme?

  2001cites this paper
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  2001cites this paper
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  2001cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
• Different structural and kinetic requirements for the interaction of Ran with the Ran-binding domains from RanBP2 and importin-beta.

  2000cites this paper
• Purification of the Vertebrate Nuclear Pore Complex by Biochemical Criteria

  2000cites this paper
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  1999cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1997cites this paper
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• SUMO-1: wrestling with a new ubiquitin-related modifier.

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• Xenopus Ran-binding protein 1: molecular interactions and effects on nuclear assembly in Xenopus egg extracts.

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• The balance of RanBP1 and RCC1 is critical for nuclear assembly and nuclear transport.

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• Citation for Published Item: Use Policy the Cytoplasmic Filaments of the Nuclear Pore Complex Are Dispensable for Selective Nuclear Protein Import

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