Chronic elevation of plasma thioredoxin: Inhibition of chemotaxis and curtailment of life expectancy in AIDS

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2001-02-27

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/pnas.041624998PMID 11226300PMCID PMC30199
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Human thioredoxin attenuates hypoxia‐reoxygenation injury of murine endothelial cells in a thiol‐free condition

  2000cited by this paper
• Neutropenia, neutrophil dysfunction, and bacterial infection in patients with human immunodeficiency virus disease: the role of granulocyte colony-stimulating factor.

  2000cited by this paper
• Serum thioredoxin levels as an indicator of oxidative stress in patients with hepatitis C virus infection.

  2000cited by this paper
• N‐acetylcysteine replenishes glutathione in HIV infection

  2000cited by this paper
• Improvement of immune functions in HIV infection by sulfur supplementation: Two randomized trials

  2000cited by this paper
• Neutrophil deficiency and dysfunction in HIV-infected patients.

  1999cited by this paper
• Thioredoxin, a Redox Enzyme Released in Infection and Inflammation, Is a Unique Chemoattractant for Neutrophils, Monocytes, and T Cells

  1999cited by this paper
• Identification of glutathione S‐transferase isozymes and γ‐glutamylcysteine synthetase as negative acute‐phase proteins in rat liver

  1998cited by this paper
• Redox Control of Neuronal Damage during Brain Ischemia after Middle Cerebral Artery Occlusion in the Rat: Immunohistochemical and Hybridization Studies of Thioredoxin

  1998cited by this paper
• Measurements of plasma glutaredoxin and thioredoxin in healthy volunteers and during open-heart surgery.

  1998cited by this paper
• Amelioration of ischemia-reperfusion injury by human thioredoxin in rabbit lung.

  1997cited by this paper
• AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1.

  1997cited by this paper
• Redox regulation of cellular activation.

  1997cited by this paper
• Glutathione deficiency is associated with impaired survival in HIV disease.

  1997cited by this paper
• Elevation of plasma thioredoxin levels in HIV-infected individuals.

  1996cited by this paper
• Protection against reperfusion-induced arrhythmias by human thioredoxin.

  1996cited by this paper
• Changes in antigen densities on leukocyte subsets correlate with progression of HIV disease.

  1996cited by this paper
• A CD4+ T cell line-secreted factor, growth promoting for normal and leukemic B cells, identified as thioredoxin.

  1995cited by this paper
• High level monocyte chemoattractant protein-1 expression in transgenic mice increases their susceptibility to intracellular pathogens.

  1995cited by this paper
• Thioredoxin structure and mechanism: conformational changes on oxidation of the active-site sulfhydryls to a disulfide.

  1995cited by this paper
• Long-term impaired neutrophil migration in mice overexpressing human interleukin-8.

  1994cited by this paper
• Regulation of eosinophil migration by adult T cell leukemia-derived factor.

  1993cited by this paper
• Human eosinophil cytotoxicity-enhancing factor. Eosinophil-stimulating and dithiol reductase activities of biosynthetic (recombinant) species with COOH-terminal deletions.

  1993cited by this paper
• Human thioredoxin/adult T cell leukemia-derived factor activates the enhancer binding protein of human immunodeficiency virus type 1 by thiol redox control mechanism.

  1992cited by this paper
• Thiordoxin regulates the DNA binding activity of NF-χB by reduction of a disulphid bond involving cysteine 62

  1992cited by this paper
• Diseases associated with HTLV-I: virus, IL-2 receptor dysregulation and redox regulation.

  1992cited by this paper
• Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62.

  1992cited by this paper
• Glutathione deficiency and human immunodeficiency virus infection.

  1992cited by this paper
• Intravascular IL-8. Inhibitor of polymorphonuclear leukocyte accumulation at sites of acute inflammation.

  1991cited by this paper
• Adult T-cell leukemia-derived factor/thioredoxin, produced by both human T-lymphotropic virus type I- and Epstein-Barr virus-transformed lymphocytes, acts as an autocrine growth factor and synergizes with interleukin 1 and interleukin 2.

  1990cited by this paper
• Role of ATL-derived factor (ADF) in the normal and abnormal cellular activation: involvement of dithiol related reduction.

  1990cited by this paper
• Role of ATL-derived factor (ADF) in the normal and abnormal cellular activation: involvement of dithiol related reduction.

  1990cited by this paper
• ATL‐derived factor (ADF), an IL‐2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol‐reduction in the IL‐2 receptor induction.

  1989cited by this paper
• Thioredoxin.

  1985cited by this paper
• Basic principles of ROC analysis.

  1978cited by this paper

• Exploring the Thioredoxin System as a Therapeutic Target in Cancer: Mechanisms and Implications

  2024cites this paper
• Thioredoxin reductase selenoproteins from different organisms as potential drug targets for treatment of human diseases.

  2022cites this paper
• Linear association between aging and decreased blood thiol antioxidant activity in patients with cataract

  2022cites this paper
• Thioredoxin Reductase Inhibition for Cancer Therapy.

  2021cites this paper
• Autonomous Non Antioxidant Roles for Fasciola hepatica Secreted Thioredoxin-1 and Peroxiredoxin-1

  2021cites this paper
• Peri/Epicellular Thiol Oxidoreductases as Mediators of Extracellular Redox Signaling

  2020cites this paper
• Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease.

  2019cites this paper
• Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin

  2018cites this paper
• Cysteine/Glutathione Deficiency: A Significant and Treatable Corollary of Disease

  2018cites this paper
• The role of the thioredoxin/thioredoxin reductase system in the metabolic syndrome: towards a possible prognostic marker?

  2018cites this paper
• Cloning and functional characterization of thioredoxin genes from large yellow croaker Larimichthys crocea

  2018cites this paper
• Implications of plasma thiol redox in disease.

  2018cites this paper
• Novel Approaches to Whole Parasite Blood-Stage Malaria Vaccine Development

  2018cites this paper
• Studying Electrotaxis in Microfluidic Devices

  2017cites this paper
• Anti-Inflammatory Thioredoxin Family Proteins for Medicare, Healthcare and Aging Care

  2017cites this paper
• Chemical Biology of H2S Signaling through Persulfidation.

  2017cites this paper
• Thiol redox barrier; local and systemic surveillance against stress and inflammatory diseases.

  2016cites this paper
• Association between systemic oxidative stress and visual field damage in open-angle glaucoma

  2016cites this paper
• Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation

  2016cites this paper
• Challenge tests and their application in nutrition research to investigate phenotypic flexibility

  2016cites this paper
• ПРИЛОЖЕНИЕ НА МЕТАБОЛИТНИ СТРЕС ТЕСТОВЕ В НАУКАТА ЗА ХРАНЕНЕТО ЗА ИЗСЛЕДВАНЕ НА ФЕНОТИПНАТА ПЛАСТИЧНОСТ

  2016cites this paper
• Thioredoxin-1 Selectively Activates Transglutaminase 2 in the Extracellular Matrix of the Small Intestine

  2016cites this paper
• The role of cellular oxidoreductases in viral entry and virus infection-associated oxidative stress: potential therapeutic applications

  2016cites this paper
• Thioredoxin superfamily and its effects on cardiac physiology and pathology.

  2015cites this paper
• Clinical Relevance of Biomarkers of Oxidative Stress

  2015cites this paper
• Modulation of oxidative damage by selenium compounds

  2015cites this paper
• Preferential regeneration of thioredoxin from parasitic flatworm Fasciola gigantica using glutathione system.

  2015cites this paper
• Redox Proteomics of the Inflammatory Secretome Identifies a Common Set of Redoxins and Other Glutathionylated Proteins Released in Inflammation, Influenza Virus Infection and Oxidative Stress

  2015cites this paper
• Correlation between Systemic Oxidative Stress and Intraocular Pressure Level

  2015cites this paper
• Thioredoxin-1 (Trx1) : a new target in the treatment of cardiovascular diseases

  2014cites this paper
• Protein moonlighting: a new factor in biology and medicine.

  2014cites this paper
• Altered glutamate cysteine ligase activity in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

  2014cites this paper
• Identification of Novel Nuclear Targets of Human Thioredoxin 1*

  2014cites this paper
• On the redox biology of the immuno-virological receptor CD4: biological function and applications in HIV-1 drug and vaccine development

  2014cites this paper
• Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.

  2014cites this paper
• The Biologicaland Biom edicalConsequences of Protein M oonlighting The Biological and Biomedical Consequences of Protein Moonlighting

  2014cites this paper
• Serum thioredoxin reductase levels increase in response to chemically induced acute liver injury.

  2014cites this paper
• Redox regulation of inflammation and immunity

  2013cites this paper
• The Thioredoxin System as a Therapeutic Target in Human Health and Disease

  2013cites this paper
• Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling

  2013cites this paper
• Cell-mediated reduction of human β-defensin 1: a major role for mucosal thioredoxin

  2013cites this paper
• Regulation of the thioredoxin system in Saccharomyces cerevisiae.

  2013influential citation
• Extracellular thioredoxin: a therapeutic tool to combat inflammation.

  2013influential citation
• Thioredoxin Ameliorates Cutaneous Inflammation by Regulating the Epithelial Production and Release of Pro-Inflammatory Cytokines

  2013cites this paper
• Cell-type specific requirements for thiol/disulfide exchange during HIV-1 entry and infection

  2012cites this paper
• Discovery of the Extracellular Agonist Actions of Molecular Chaperones and Protein-Folding Catalysts

  2012cites this paper
• Status of Systemic Oxidative Stresses in Patients with Primary Open-Angle Glaucoma and Pseudoexfoliation Syndrome

  2012cites this paper
• Cellular Trafficking of Cell Stress Proteins in Health and Disease

  2012cites this paper
• Su1727 Attenuation of Indomethacin-Induced Gastric Mucosal Injury With Prophylactic Administration of Sake Yeast-Derived Thioredoxin

  2012cites this paper
• Attenuation of indomethacin-induced gastric mucosal injury by prophylactic administration of sake yeast-derived thioredoxin

  2012cites this paper
• Disulfide Proteomics: Current Status in Thioredoxin Biochemistry and Industrial Research

  2012cites this paper
• Loss of mitochondrial thioredoxin reductase delays angiogenic switch and impairs tumour growth

  2011cites this paper
• The Human Thioredoxin System: Modifications and Clinical Applications

  2011cites this paper
• Serum manganese superoxide dismutase and thioredoxin are potential prognostic markers for hepatitis C virus-related hepatocellular carcinoma.

  2011cites this paper
• Thioredoxin in Allergic Inflammation

  2011cites this paper
• Mechanisms and genes involved in enhancement of HIV infectivity by tobacco smoke.

  2010influential citation
• Molecular chaperones and protein‐folding catalysts as intercellular signaling regulators in immunity and inflammation

  2010cites this paper
• Naturally occurring free thiols within beta 2-glycoprotein I in vivo: nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress-induced cell injury.

  2010cites this paper
• Redox Control of Asthma: Molecular Mechanisms and Therapeutic Opportunities

  2010cites this paper
• Thiol redox transitions by thioredoxin and thioredoxin-binding protein-2 in cell signaling.

  2010cites this paper
• Thioredoxin and thioredoxin reductase: current research with special reference to human disease.

  2010cites this paper
• Serum C-reactive protein and thioredoxin levels in subjects with mildly reduced glomerular filtration rate

  2010cites this paper
• Protein expression analysis of inflammation-related colon carcinogenesis

  2009cites this paper
• Bacterial Thioredoxins-Genes and Regulation

  2009cites this paper
• High-Level Production, Solubilization and Purification of Synthetic Human GPCR Chemokine Receptors CCR5, CCR3, CXCR4 and CX3CR1

  2009cites this paper
• Thioredoxin in human and experimental sepsis*

  2009cites this paper
• Complex Redundancy between the Mammalian Thioredoxin and Glutathione Systems in Cell Proliferation and Tumorigenesis Thesis

  2009cites this paper
• Thioredoxin-Binding Protein-2 Deficiency Enhances Methionine-Choline Deficient Diet-Induced Hepatic Steatosis But Inhibits Steatohepatitis in Mice

  2009cites this paper
• Unfolding the relationship between secreted molecular chaperones and macrophage activation states

  2009cites this paper
• High-Level Production , Solubilization and Purification of Synthetic Human GPCR Chemokine Receptors CCR 5 , CCR 3 , CXCR 4 and CX 3 CR 1

  2009cites this paper
• Identification of novel cytosolic thioredoxin-1 target proteins in mammalian cells by mechanism-based kinetic trapping

  2008cites this paper
• Emerging potential of thioredoxin and thioredoxin interacting proteins in various disease conditions.

  2008cites this paper
• Induction of IFN-γ gene Expression by Thioredoxin: Positive Feed-Back Regulation of Th1 Response by Thioredoxin and IFN-γ

  2008cites this paper
• Oxidative stress and HIV infection: target pathways for novel therapies?

  2008cites this paper
• Human thioredoxin exerts cardioprotective effect and attenuates reperfusion injury in rats partially via inhibiting apoptosis

  2008cites this paper
• Redox regulation in the extracellular environment.

  2008cites this paper
• REGULATION OF HUMAN THIOREDOXIN AND GLUTAREDOXIN SYSTEMS BY OXIDATION AND S-NITROSYLATION

  2008influential citation
• Redox compartmentalization in eukaryotic cells.

  2008cites this paper
• Redox-Regulated Mechanisms in Asthma

  2008cites this paper
• Decreased selenoprotein expression alters the immune response during influenza virus infection in mice.

  2007cites this paper
• beta(2)-Adrenergic receptor-dependent sexual dimorphism for murine leukocyte migration.

  2007cites this paper
• Lipid Raft–Mediated Uptake of Cysteine-Modified Thioredoxin-1: Apoptosis Enhancement by Inhibiting the Endogenous Thioredoxin-1

  2007cites this paper
• Thioredoxin and Related Molecules–From Biology to Health and Disease

  2007cites this paper
• Elevation of serum thioredoxin in patients with gefitinib-induced interstitial lung disease.

  2007cites this paper
• Thioredoxins and gene regulation in the Drosophila germline

  2007cites this paper
• Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1

  2007influential citation
• Oxygen Sensing : Life and Death of a Cell Oxygen sensing and redox signaling : the role of thioredoxin in embryonic development and cardiac diseases

  2007cites this paper
• Nucleoredoxin, a Novel Thioredoxin Family Member Involved in Cell Growth and Differentiation

  2007cites this paper
• Oxidation and S-Nitrosylation of Cysteines in Human Cytosolic and Mitochondrial Glutaredoxins

  2007cites this paper
• Pancreatic B-cell function is altered by oxidative stress induced by acute hyperglycaemia

  2007cites this paper
• Expression of thioredoxin and thioredoxin-binding protein-2 in the liver of patients with chronic hepatitis C as a predictor of response to interferon therapy.

  2006cites this paper
• [Non-alcoholic steatohepatitis. 3. Oxidative stress and NASH].

  2006cites this paper
• Extracellular thioredoxin and thioredoxin-binding protein 2 in control of cancer.

  2006cites this paper
• Effect of iron reduction by phlebotomy in Japanese patients with nonalcoholic steatohepatitis: A pilot study.

  2006cites this paper
• Human thioredoxin-1 ameliorates experimental murine colitis in association with suppressed macrophage inhibitory factor production.

  2006cites this paper
• High redox thioredoxin but low thioredoxin reductase activities in the serum of patients with rheumatoid arthritis.

  2006cites this paper
• Functional characterization of cytosolic and mitochondrial thioredoxin reductases

  2006cites this paper
• ORIGINAL ARTICLE

  2006cites this paper
• Cytoprotective Effects of Geranylgeranylacetone against Retinal Photooxidative Damage

  2005cites this paper
• Requirements for the Different Cysteines in the Chemotactic and Desensitizing Activity of Human Thioredoxin

  2005cites this paper