Protein kinase cascades activated by stress and inflammatory cytokines

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Bioessays

• Publication date

  1996-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/bies.950180708PMID 8757935
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cloning and characterization of the

  1996cited by this paper
• Ischemia and Reperfusion Enhance ATF-2 and c-Jun Binding to cAMP Response Elements and to an AP-1 Binding Site from the c-jun Promoter (*)

  1995cited by this paper
• p493F12 kinase: a novel MAP kinase expressed in a subset of neurons in the human nervous system.

  1995cited by this paper
• Activation of ternary complex factor Elk-1 by stress-activated protein kinases.

  1995cited by this paper
• Ste5: a meeting place for MAP kinases and their associates.

  1995cited by this paper
• Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors.

  1995cited by this paper
• Cloning and Characterization of a Human Protein Kinase with Homology to Ste20 (*)

  1995cited by this paper
• Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine (*)

  1995cited by this paper
• Evidence for Multiple Activators for Stress-activated Protein Kinases/c-Jun Amino-terminal Kinases.

  1995cited by this paper
• Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein.

  1995cited by this paper
• Stress-activated protein kinases bind directly to the delta domain of c-Jun in resting cells: implications for repression of c-Jun function.

  1995cited by this paper
• Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway

  1995cited by this paper
• The proliferation of MAP kinase signaling pathways in yeast.

  1995cited by this paper
• Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

  1995cited by this paper
• Ceramide Activates the Stress-activated Protein Kinases (*)

  1995cited by this paper
• Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1 (*)

  1995cited by this paper
• Components of a New Human Protein Kinase Signal Transduction Pathway (*)

  1995cited by this paper
• Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

  1995cited by this paper
• Direct Interaction between Ras and the Kinase Domain of Mitogen-activated Protein Kinase Kinase Kinase (MEKK1) (*)

  1995cited by this paper
• A novel serine kinase activated by rac1/CDC42Hs‐dependent autophosphorylation is related to PAK65 and STE20.

  1995cited by this paper
• A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

  1995cited by this paper
• Two-component signal-transduction systems in budding yeast MAP a different pathway?

  1995cited by this paper
• Association of the yeast pheromone response G protein beta gamma subunits with the MAP kinase scaffold Ste5p.

  1995cited by this paper
• Protein Kinase Byr2 Is a Target of Ras1 in the Fission Yeast Schizosaccharomyces pombe(*)

  1995cited by this paper
• An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

  1995cited by this paper
• Molecular Characterization of Ste20p, a Potential Mitogen-activated Protein or Extracellular Signal-regulated Kinase Kinase (MEK) Kinase Kinase from Saccharomyces cerevisiae(*)

  1995cited by this paper
• Transcription factor ATF2 regulation by the JNK signal transduction pathway

  1995cited by this paper
• The Stress‐activated Protein Kinases

  1995cited by this paper
• MAP kinase pathways in yeast: for mating and more.

  1995cited by this paper
• Integration of MAP kinase signal transduction pathways at the serum response element.

  1995cited by this paper
• Identification of a Mouse p21Cdc42/Rac Activated Kinase (*)

  1995cited by this paper
• Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor.

  1995cited by this paper
• Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

  1995cited by this paper
• Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs.

  1995cited by this paper
• Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

  1994cited by this paper
• A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins.

  1994cited by this paper
• Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK.

  1994cited by this paper
• Ras-dependent growth factor regulation of MEK kinase in PC12 cells.

  1994cited by this paper
• Differential expression of a novel protein kinase in human B lymphocytes. Preferential localization in the germinal center.

  1994cited by this paper
• Cloning and characterization of p97MAPK, a novel human homolog of rat ERK-3

  1994cited by this paper
• The sphingomyelin cycle and the second messenger function of ceramide.

  1994cited by this paper
• A brain serine/threonine protein kinase activated by Cdc42 and Rac1

  1994cited by this paper
• Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

  1994cited by this paper
• A two-component system that regulates an osmosensing MAP kinase cascade in yeast

  1994cited by this paper
• The stress-activated protein kinase subfamily of c-Jun kinases

  1994cited by this paper
• Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

  1994cited by this paper
• Mutation of the SPS1-encoded protein kinase of Saccharomyces cerevisiae leads to defects in transcription and morphology during spore formation.

  1994cited by this paper
• JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.

  1994cited by this paper
• Raf meets Ras: completing the framework of a signal transduction pathway.

  1994cited by this paper
• The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion.

  1994cited by this paper
• A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

  1994cited by this paper
• Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

  1994cited by this paper
• Signal transduction by tumor necrosis factor mediated by JNK protein kinases

  1994cited by this paper
• A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells.

  1994cited by this paper
• A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

  1993cited by this paper
• Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

  1993cited by this paper
• Substrate recognition by ceramide-activated protein kinase. Evidence that kinase activity is proline-directed.

  1993cited by this paper
• Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

  1992cited by this paper
• Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun: regulation by the N-terminal delta domain.

  1992cited by this paper
• The protein kinase homologue Ste20p is required to link the yeast pheromone response G‐protein beta gamma subunits to downstream signalling components.

  1992cited by this paper
• An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase.

  1992cited by this paper
• Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases.

  1992cited by this paper
• The mitogen-activated protein kinase activator.

  1992cited by this paper
• MAPKAP kinase‐2; a novel protein kinase activated by mitogen‐activated protein kinase.

  1992cited by this paper
• Heterogeneous expression of four MAP kinase isoforms in human tissues

  1992cited by this paper
• Phosphorylation of c-jun mediated by MAP kinases

  1991cited by this paper
• ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF.

  1991cited by this paper
• pp54 microtubule-associated protein-2 kinase requires both tyrosine and serine/threonine phosphorylation for activity.

  1991cited by this paper
• Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

  1990cited by this paper
• pp54 microtubule-associated protein 2 kinase. A novel serine/threonine protein kinase regulated by phosphorylation and stimulated by poly-L-lysine.

  1990cited by this paper
• An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control.

  1990cited by this paper
• Activation of Yeast PBS 2 MAPKK by MAPKKKs or by Binding of an SH 3-Containing Osmosensor

  year unknowncited by this paper

• Experimental and clinical perspectives on glycocalyx integrity and its relation to acute respiratory distress syndrome.

  2025cites this paper
• Immunocompatibility and Antioxidant Shielding Effects of Alginate-Based Hybrid Hydrogels for Tissue Engineering

  2025cites this paper
• Anticancer Properties of Phenylboronic Acid in Androgen-Dependent (LNCaP) and Androgen-Independent (PC3) Prostate Cancer Cells via MAP Kinases by 2D and 3D Culture Methods.

  2025cites this paper
• Anti-Inflammatory and Antimicrobial Effect of Ellagic Acid and Punicalagin in Dermal Fibroblasts

  2025cites this paper
• Effects of Cheonwangbosim-dan in a Mouse Model of Chronic Obstructive Pulmonary Disease: Anti-Inflammatory and Anti-Fibrotic Therapy

  2023cites this paper
• Amyloid-beta peptide induces oligodendrocyte death by activating Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway the neutral sphingomyelinase-ceramide pathway

  2022cites this paper
• Multi-stage virtual screening of natural products against p38α mitogen-activated protein kinase: predictive modeling by machine learning, docking study and molecular dynamics simulation

  2022cites this paper
• Dissection of the Regulatory Elements of the Complex Expression Pattern of Puckered, a Dual-Specificity JNK Phosphatase

  2021cites this paper
• Viral Suppression of RIPK1-Mediated Signaling

  2021cites this paper
• Inflammation and JNK's Role in Niacin-GPR109A Diminished Flushed Effect in Microglial and Neuronal Cells With Relevance to Schizophrenia

  2021cites this paper
• Antioxidant and Anti-Inflammatory Potential of Polyphenols Contained in Mediterranean Diet in Obesity: Molecular Mechanisms

  2021cites this paper
• Phosphorylation Sites in Protein Kinases and Phosphatases Regulated by Formyl Peptide Receptor 2 Signaling

  2020cites this paper
• TRPV1 Antagonist DWP05195 Induces ER Stress-Dependent Apoptosis through the ROS-p38-CHOP Pathway in Human Ovarian Cancer Cells

  2020cites this paper
• A cell permeant phosphopeptide mimetic of Niban inhibits p38 MAPK and restores endothelial function after injury

  2020cites this paper
• Regulation of the Mammalian SWI/SNF Family of Chromatin Remodeling Enzymes by Phosphorylation during Myogenesis

  2020cites this paper
• Celecoxib upregulates ULBP-1 expression in lung cancer cells via the JNK/PI3K signaling pathway and increases susceptibility to natural killer cell cytotoxicity

  2020cites this paper
• Discovery and development of ASK1 inhibitors.

  2020cites this paper
• Gearing Up for Warmer Times: Transcriptomic Response of Spongia officinalis to Elevated Temperatures Reveals Recruited Mechanisms and Potential for Resilience

  2020cites this paper
• Chloroquine promotes gefitinib-induced apoptosis by inhibiting protective autophagy in cutaneous squamous cell carcinoma

  2019cites this paper
• Lysozyme-Induced Transcriptional Regulation of TNF-α Pathway Genes in Cells of the Monocyte Lineage

  2019cites this paper
• JLP-centrosome is essential for the microtubule-mediated nucleocytoplasmic transport induced by extracellular stimuli

  2019cites this paper
• Development of a p38α-selective radioactive probe for qualitative diagnosis of cancer using SPECT

  2019cites this paper
• Involvement of mitogen-activated protein kinase pathways in ferrous iron-induced aquaporin-4 expression in cultured astrocytes.

  2019cites this paper
• Group Family Inhibitor Drugs Receptors EGFR Erlotinib Gefitinib Lapatinib VEGFR Sunitinib Imatinib Sorafenib

  2019cites this paper
• Spred negatively regulates lens growth by modulating epithelial cell proliferation and fiber differentiation

  2019cites this paper
• 4-O-Carboxymethylascochlorin Inhibits Expression Levels of on Inflammation-Related Cytokines and Matrix Metalloproteinase-9 Through NF–κB/MAPK/TLR4 Signaling Pathway in LPS-Activated RAW264.7 Cells

  2019influential citation
• Normal Saline solutions cause endothelial dysfunction through loss of membrane integrity, ATP release, and inflammatory responses mediated by P2X7R/p38 MAPK/MK2 signaling pathways

  2019cites this paper
• Accumulation of tissue factor in endothelial cells promotes cellular apoptosis through over-activation of Src1 and involves β1-integrin signalling

  2019cites this paper
• E-p-Methoxycinnamoyl-α-l-rhamnopyranosyl Ester, a Phenylpropanoid Isolated from Scrophularia buergeriana, Increases Nuclear Factor Erythroid-Derived 2-Related Factor 2 Stability by Inhibiting Ubiquitination in Human Keratinocytes

  2018cites this paper
• Evaluation of Potassium Dichromate (K2Cr2O7)-Induced Liver Oxidative Stress and Ameliorative Effect of Picrorhiza kurroa Extract in Wistar Albino Rats

  2018cites this paper
• Anti-inflammatory effect of lysozyme from hen egg white on mouse peritoneal macrophages

  2018cites this paper
• Application of brain tumor proton MRSI in children Localized

  2018cites this paper
• The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice

  2018cites this paper
• 11 Pediatric Brain Tumors : Magnetic Resonance Spectroscopic Imaging

  2018cites this paper
• Simultaneous stimulation with tumor necrosis factor-α and transforming growth factor-β1 induces epithelial-mesenchymal transition in colon cancer cells via the NF-κB pathway

  2018cites this paper
• Effects of Urotensin II on Excitation-Contraction Coupling in Hypertrophic Heart Failure

  2018cites this paper
• Differentiation by NK cells is a prerequisite for effective targeting of cancer stem cells/poorly differentiated tumors by chemopreventive and chemotherapeutic drugs

  2017cites this paper
• Differences in Gene Expression and Gene Associations in Epicardial Fat Compared to Subcutaneous Fat

  2017cites this paper
• p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells

  2017cites this paper
• The protective mechanism of QGC in feline esophageal epithelial cells by interleukin-1β treatment

  2017cites this paper
• Overexpressing OsMAPK12-1 inhibits plant growth and enhances resistance to bacterial disease in rice.

  2017cites this paper
• A diet of fructose‐enriched Artemia improves the response of juvenile Litopenaeus vannamei shrimp to acute low‐salinity challenge

  2017cites this paper
• The role of neutrophils in telomere induced senescence via bystander effects

  2017cites this paper
• Biphasic Dose–Response Phenomenon Induced by Xenobiotics and Its Application in Soil Risk Assessment

  2017cites this paper
• ofacitinib and Other Kinase Inhibitors in the Treatment of soriasis

  2017cites this paper
• p38 MAPK Signalling in Endothelial Apoptosis

  2017cites this paper
• Plasma membrane reorganization links acid sphingomyelinase/ceramide to p38 MAPK pathways in endothelial cells apoptosis.

  2017cites this paper
• Macrophage migration inhibitory factor: a potential therapeutic target for rheumatoid arthritis

  2016cites this paper
• Analyzing ERK 1/2 signalling and targets.

  2016cites this paper
• via Toll-like receptor 2 in tracheal smooth muscle cells Lipoteichoic acid-stimulated p42/p44 MAPK activation

  2016cites this paper
• Differential Expression of the Activator Protein 1 Transcription Factor Regulates Interleukin-1ß Induction of Interleukin 6 in the Developing Enterocyte

  2016cites this paper
• Régulation de la prolifération des cellules musculaires lisses vasculaires par l’activation in vivo du récepteur natriurétique de type C

  2016cites this paper
• MINISYMPOSIUM: PEDIATRIC MR SPECTROSCOPY Proton MRS imaging in pediatric brain tumors

  2016cites this paper
• prostanoid production in cardiac myocytes Phorbol ester stimulates cyclooxygenase-2 expression and

  2016cites this paper
• Rôle pro-inflammatoire des cellules épithéliales de la conjonctive dans un modèle in vitro de sécheresse oculaire

  2016cites this paper
• The protective mechanism of QGC in feline esophageal epithelial cells by interleukin-1β treatment

  2016cites this paper
• The Role of Oxidative Stress in the Mechanisms of Ammonia-Induced Brain Swelling and Tolerance in the Goldfish (Carassius auratus)

  2016cites this paper
• L-DOPA modulates cell viability through the ERK-c-Jun system in PC12 and dopaminergic neuronal cells.

  2016cites this paper
• Phytoconstituents as apoptosis inducing agents: strategy to combat cancer

  2016cites this paper
• Klinikum rechts der Isar Inhibition of MCL-1 blocks the development of KRAS-driven adenocarcinoma of the lung Enkhtsetseg Munkhbaatar

  2015cites this paper
• Deoxysappanone B, a homoisoflavone from the Chinese medicinal plant Caesalpinia sappan L., protects neurons from microglia-mediated inflammatory injuries via inhibition of IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways.

  2015cites this paper
• Sambucus Williamsii Hance Promotes MC3T3‐E1 Cells Proliferation and Differentiation via BMP‐2/Smad/p38/JNK/Runx2 Signaling Pathway

  2015cites this paper
• ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice.

  2015cites this paper
• Voies de signalisation des MAP kinases et apoptose

  2015cites this paper
• shockand signaling pathways in survival of heat Invited Review: Interplay between molecular

  2015cites this paper
• Stanniocalcin-1 inhibits thrombin-induced signaling and protects from bleomycin-induced lung injury

  2015cites this paper
• In vivo biodistribution and toxicity of Gd2O3:Eu3+ nanotubes in mice after intraperitoneal injection

  2015cites this paper
• Effect of Heme Oxygenase-1 on Matrix Metalloproteinase-3 Expression in Human Fibroblasts

  2014cites this paper
• Growth, bioluminescence and shoal behavior hormetic responses to inorganic and/or organic chemicals: a review.

  2014cites this paper
• Geldanamycin attenuates 3-nitropropionic acid-induced apoptosis and JNK activation through the expression of HSP 70 in striatal cells

  2014cites this paper
• Pathways by Tumorigenic Mutant p53 Inhibition of Stress-Inducible Kinase

  2014influential citation
• Epigallocatechin-3-gallate, a green tea catechin, protects the heart against regional ischemia–reperfusion injuries through activation of RISK survival pathways in rats

  2014cites this paper
• A small molecule, MTBT, prevents cancer cell growth by activating p38 MAPK

  2014cites this paper
• Mixed-Lineage Kinase 3 Deficiency Promotes Neointima Formation Through Increased Activation of the RhoA Pathway in Vascular Smooth Muscle Cells

  2014cites this paper
• Mecanismos de regulación de la muerte del oocito por shock hiperosmótico

  2014cites this paper
• 14-3-3 and aggresome formation: Implications in neurodegenerative diseases

  2014cites this paper
• Effects of a novel curcumin derivative on insulin synthesis and secretion in streptozotocin-treated rat pancreatic islets in vitro

  2014cites this paper
• Dissection of Enzymatic Phosphoryl Transfer: from Substrate Recognition to the Transition state

  2013cites this paper
• 4,5-dianilinophtalimide protects neuroendocrine cells against serum deprivation-induced stress and apoptosis.

  2013cites this paper
• Inhibition of CK 2 enhances UV-triggered apoptotic cell death in lung cancer cell lines

  2013cites this paper
• High yield purification of JNK1β1 and activation by in vitro reconstitution of the MEKK1→MKK4→JNK MAPK phosphorylation cascade.

  2013cites this paper
• Tofacitinib and other kinase inhibitors in the treatment of psoriasis.

  2013cites this paper
• Genomic architecture of bovine κ-casein and β-lactoglobulin.

  2013cites this paper
• SCO2 Induces p53-Mediated Apoptosis by Thr845 Phosphorylation of ASK-1 and Dissociation of the ASK-1–Trx Complex

  2013cites this paper
• Dual p38/JNK Mitogen Activated Protein Kinase Inhibitors Prevent Ozone-Induced Airway Hyperreactivity in Guinea Pigs

  2013cites this paper
• Vital pulp therapy.

  2013cites this paper
• TRASTORNOS INMUNOLOGICOS INDUCIDOS POR MERCURIO EN EL SISTEMA REPRODUCTOR MASCULINO HUMANO MERCURY-INDUCED IMMUNOLOGICAL DAMAGE IN MALE REPRODUCTIVE SYSTEM

  2013cites this paper
• Inhibition of CK2 enhances UV-triggered apoptotic cell death in lung cancer cell lines.

  2013cites this paper
• TNF-α modulation of intestinal epithelial tight junction barrier is regulated by ERK1/2 activation of Elk-1.

  2013cites this paper
• Molecular and Genetic Analysis of a Conserved Transcription Factor with a Role in Promoting the Completion of Cytokinesis in Schizosaccharomyces pombe

  2013cites this paper
• TNF-a Modulation of Intestinal Epithelial Tight Junction Barrier Is Regulated by ERK1/2 Activation of Elk-1

  2013cites this paper
• Epidermal growth factor receptor expression and signaling are essential in glutamine's cytoprotective mechanism in heat-stressed intestinal epithelial-6 cells.

  2013cites this paper
• Tofacitinib y otros inhibidores de las cinasas en el tratamiento de la psoriasis

  2013cites this paper
• Phosphorylations of Sds23/Psp1/Moc1 by stress‐activated kinase and cAMP‐dependent kinase are essential for regulating cell viability in prolonged stationary phase

  2013cites this paper
• P38MAP kinase, but not phosphoinositol-3 kinase, signal downstream of glutamine-mediated fibronectin-integrin signaling after intestinal injury

  2013cites this paper
• 3 – The Tear Film: Anatomy, Structure and Function

  2013cites this paper
• Gene expression profiling of nephrotoxicity from copper nanoparticles in rats after repeated oral administration.

  2012cites this paper
• Gene expression profiles of human lung epithelial cells exposed to toluene

  2012cites this paper
• Enzyme Kinetics and Interaction Studies for Human JNK1β1 and Substrates Activating Transcription Factor 2 (ATF2) and c-Jun N-terminal kinase (c-Jun)*

  2012cites this paper
• The many faces of p38 mitogen-activated protein kinase in progenitor/stem cell differentiation.

  2012cites this paper