OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , 114 ( 10 ) ISSN 0027-8424

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  2015cited by this paper
• SAMHD1's protein expression profile in humans

  2015cited by this paper
• Molecular Determinants for Recognition of Divergent SAMHD1 Proteins by the Lentiviral Accessory Protein Vpx

  2015cited by this paper
• Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration

  2014cited by this paper
• HIV-1 uncoating: connection to nuclear entry and regulation by host proteins.

  2014cited by this paper
• The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation.

  2013cited by this paper
• Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.

  2013cited by this paper
• Structural basis of lentiviral subversion of a cellular protein degradation pathway

  2013cited by this paper
• Evolutionary Toggling of Vpx/Vpr Specificity Results in Divergent Recognition of the Restriction Factor SAMHD1

  2013cited by this paper
• Restrictions to HIV-1 replication in resting CD4+ T lymphocytes

  2013cited by this paper
• Restricting HIV the SAMHD1 way: through nucleotide starvation

  2012cited by this paper
• SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

  2012cited by this paper
• SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4+ T-cells

  2012cited by this paper
• SAMHD1 restricts HIV-1 infection in resting CD4+ T cells

  2012influential reference
• The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.

  2012cited by this paper
• Tight Interplay among SAMHD1 Protein Level, Cellular dNTP Levels, and HIV-1 Proviral DNA Synthesis Kinetics in Human Primary Monocyte-derived Macrophages*

  2012cited by this paper
• Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon

  2011cited by this paper
• SAMHD1-Deficient CD14+ Cells from Individuals with Aicardi-Goutières Syndrome Are Highly Susceptible to HIV-1 Infection

  2011influential reference
• SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

  2011influential reference
• Human Immunodeficiency Virus Type 1 Modified To Package Simian Immunodeficiency Virus Vpx Efficiently Infects Macrophages and Dendritic Cells

  2011cited by this paper
• Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

  2011influential reference
• HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

  2011cited by this paper
• A cellular restriction dictates the permissivity of nondividing monocytes/macrophages to lentivirus and gammaretrovirus infection.

  2009cited by this paper
• Evidence for an Activation Domain at the Amino Terminus of Simian Immunodeficiency Virus Vpx

  2009influential reference
• A one-step SYBR Green I-based product-enhanced reverse transcriptase assay for the quantitation of retroviruses in cell culture supernatants.

  2009cited by this paper
• The Human Immunodeficiency Virus Type 2 Vpx Protein Usurps the CUL4A-DDB1DCAF1 Ubiquitin Ligase To Overcome a Postentry Block in Macrophage Infection

  2009cited by this paper
• Lentiviral Vpx Accessory Factor Targets VprBP/DCAF1 Substrate Adaptor for Cullin 4 E3 Ubiquitin Ligase to Enable Macrophage Infection

  2008cited by this paper
• Characterization of Simian Immunodeficiency Virus SIVSM/Human Immunodeficiency Virus Type 2 Vpx Function in Human Myeloid Cells

  2008influential reference
• Vpx Is Critical for Reverse Transcription of the Human Immunodeficiency Virus Type 2 Genome in Macrophages

  2008cited by this paper
• HIV-susceptible transgenic rats allow rapid preclinical testing of antiviral compounds targeting virus entry or reverse transcription

  2007cited by this paper
• Addition of Deoxynucleosides Enhances Human Immunodeficiency Virus Type 1 Integration and 2LTR Formation in Resting CD4+ T Cells

  2007cited by this paper
• SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells

  2007influential reference
• Rodent Cells Support Key Functions of the Human Immunodeficiency Virus Type 1 Pathogenicity Factor Nef

  2005influential reference
• The Maturation of Dendritic Cells Results in Postintegration Inhibition of HIV-1 Replication1

  2001cited by this paper
• Vpx association with mature core structures of HIV-2.

  1996cited by this paper
• HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure.

  1991cited by this paper
• The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophage

  1991cited by this paper
• HIV‐1 replication is controlled at the level of T cell activation and proviral integration.

  1990cited by this paper

• Purified recombinant lentiviral Vpx proteins maintain their SAMHD1 degradation efficiency in resting CD4+ T cells.

  2023cites this paper
• Tissue‐like environments shape functional interactions of HIV‐1 with immature dendritic cells

  2023cites this paper
• Removal of evolutionarily conserved functional MYC domains in a tilapia cell line using a vector-based CRISPR/Cas9 system

  2023cites this paper
• Antiretroviral Treatment of HIV-2 Infection: Available Drugs, Resistance Pathways, and Promising New Compounds

  2023cites this paper
• CRISPR/Cas9 knock-in strategy to evaluate phospho-regulation of SAMHD1

  2022cites this paper
• HIV-1 Infection of Long-Lived Hematopoietic Precursors In Vitro and In Vivo

  2022cites this paper
• HUSH-mediated HIV silencing is independent of TASOR phosphorylation on threonine 819

  2022cites this paper
• HIV-2/SIV Vpx antagonises NF-κB activation by targeting p65

  2021cites this paper
• to Lipopolysaccharide Adaptive Immune Response in Mice Exposed SAMHD1 Promotes the Antiretroviral

  2021cites this paper
• Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4+ T cells allows complex functional analyses

  2021cites this paper
• Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx

  2021cites this paper
• Next-Generation Sequencing in a Direct Model of HIV Infection Reveals Important Parallels to and Differences from In Vivo Reservoir Dynamics

  2020cites this paper
• Viral protein X unlocks the nuclear pore complex through a human Nup153-dependent pathway to promote nuclear translocation of the lentiviral genome

  2020cites this paper
• Involvement of SAMHD1 in dNTP homeostasis and the maintenance of genomic integrity and oncotherapy (Review).

  2020cites this paper
• Toward a Macaque Model of HIV-1 Infection: Roadblocks, Progress, and Future Strategies

  2020cites this paper
• Y44A Mutation in the Acidic Domain of HIV-2 Tat Impairs Viral Reverse Transcription and LTR-Transactivation

  2020cites this paper
• The role of human SAMHD1 in restricting porcine endogenous retroviruses (PERVs) and the innate immune response to PERV infection in human primary immune cells

  2020cites this paper
• HUSH, a Link Between Intrinsic Immunity and HIV Latency

  2019cites this paper
• Delivery of gene therapy to resting immune cells for an HIV cure

  2019cites this paper
• T cell receptor–triggered nuclear actin network formation drives CD4+ T cell effector functions

  2019cites this paper
• HIV-2/SIV Vpx targets a novel functional domain of STING to selectively inhibit cGAS–STING-mediated NF-κB signalling

  2019cites this paper
• HIV-2 Depletes CD4 T Cells through Pyroptosis despite Vpx-Dependent Degradation of SAMHD1

  2019influential citation
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  2019cites this paper
• HIV-1 Nef Disrupts CD4+ T Lymphocyte Polarity, Extravasation, and Homing to Lymph Nodes via Its Nef-Associated Kinase Complex Interface

  2018cites this paper
• CD4+ T Cell Subsets and Pathways to HIV Latency

  2018cites this paper
• SAMHD1 Phosphorylation Coordinates the Anti-HIV-1 Response by Diverse Interferons and Tyrosine Kinase Inhibition

  2018cites this paper
• SAMHD1: mechanisms of regulation and viral evasion.

  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper