Myosin Ia is Required for CFTR Brush Border Membrane Trafficking and Ion Transport in the Mouse Small Intestine

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Traffic : the International Journal of Intracellular Transport

• Publication date

  2012-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1600-0854.2012.01368.xPMID 22510086PMCID PMC3396755
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Myosin VI is required for maintenance of brush border structure, composition, and membrane trafficking functions in the intestinal epithelial cell

  2012cited by this paper
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  2011cited by this paper
• Intestinal alkaline phosphatase: multiple biological roles in maintenance of intestinal homeostasis and modulation by diet.

  2010cited by this paper
• α-AP-2 Directs Myosin VI-dependent Endocytosis of Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels in the Intestine*

  2010cited by this paper
• Differential Localization and Dynamics of Class I Myosins in the Enterocyte Microvillus

  2010cited by this paper
• Syntaxin 3 is necessary for cAMP- and cGMP-regulated exocytosis of CFTR: implications for enterotoxigenic diarrhea.

  2010influential reference
• The switch of intestinal Slc26 exchangers from anion absorptive to HCOFormula secretory mode is dependent on CFTR anion channel function.

  2010cited by this paper
• The switch of intestinal Slc26 exchangers from anion absorptive to HCO 3 (cid:1) secretory mode is dependent on CFTR anion channel function

  2010cited by this paper
• Control of cell membrane tension by myosin-I

  2009cited by this paper
• The enterocyte microvillus is a vesicle-generating organelle

  2009cited by this paper
• Rab11b regulates the apical recycling of the cystic fibrosis transmembrane conductance regulator in polarized intestinal epithelial cells.

  2009cited by this paper
• CFTR in a lipid raft-TNFR1 complex modulates gap junctional intercellular communication and IL-8 secretion.

  2008cited by this paper
• MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity

  2008cited by this paper
• CFTR and its key role in in vivo resting and luminal acid‐induced duodenal HCO3− secretion

  2008cited by this paper
• Myosins: A Superfamily of Molecular Motors

  2008cited by this paper
• Rectal Potential Difference and the Functional Expression of CFTR in the Gastrointestinal Epithelia in Cystic Fibrosis Mouse Models

  2008cited by this paper
• Myosin 1E interacts with synaptojanin‐1 and dynamin and is involved in endocytosis

  2007cited by this paper
• Myosin-1a powers the sliding of apical membrane along microvillar actin bundles

  2007cited by this paper
• Defective CFTR Apical Endocytosis and Enterocyte Brush Border in Myosin VI‐Deficient Mice

  2007influential reference
• Myosin VI targeting to clathrin-coated structures and dimerization is mediated by binding to Disabled-2 and PtdIns(4,5)P2

  2007cited by this paper
• CHAPTER 76 – Integrative Physiology and Pathophysiology of Intestinal Electrolyte Transport

  2006cited by this paper
• Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation.

  2006cited by this paper
• Quantitative immunohistochemistry of fluorescence labelled probes using low-cost software.

  2005cited by this paper
• Myosin-1a is critical for normal brush border structure and composition.

  2005influential reference
• STa and cGMP stimulate CFTR translocation to the surface of villus enterocytes in rat jejunum and is regulated by protein kinase G.

  2005cited by this paper
• A role for myosin-1A in the localization of a brush border disaccharidase

  2004cited by this paper
• Myosin VI: cellular functions and motor properties.

  2004cited by this paper
• Bioelectric measurement of CFTR function in mice.

  2002cited by this paper
• Identification of an apical Cl(-)/HCO3(-) exchanger in the small intestine.

  2002cited by this paper
• Myosin-VIIb, a novel unconventional myosin, is a constituent of microvilli in transporting epithelia.

  2001cited by this paper
• Motor domain-dependent localization of myo1b (myr-1).

  2001cited by this paper
• Kinetic Mechanism and Regulation of Myosin VI*

  2001cited by this paper
• Sucrase-isomaltase is an adenosine 3',5'-cyclic monophosphate-dependent epithelial chloride channel.

  2001cited by this paper
• Identification of transport abnormalities in duodenal mucosa and duodenal enterocytes from patients with cystic fibrosis.

  2000cited by this paper
• Cellular localization of the cystic fibrosis transmembrane conductance regulator in mouse intestinal tract

  2000cited by this paper
• Cloning and characterization of mouse brush border myosin-I in adult and embryonic intestine.

  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
• Functions of lipid rafts in biological membranes.

  1998cited by this paper
• Human brush border myosin-I and myosin-Ic expression in human intestine and Caco-2BBe cells.

  1998cited by this paper
• Kinetic characterization of brush border myosin-I ATPase.

  1997cited by this paper
• X-ray microanalysis of cell elements in normal and cystic fibrosis jejunum: evidence for chloride secretion in villi.

  1996cited by this paper
• Differential regulation of skeletal muscle myosin-II and brush border myosin-I enzymology and mechanochemistry by bacterially produced tropomyosin isoforms.

  1994cited by this paper
• Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.

  1994cited by this paper
• Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model.

  1994cited by this paper
• Multiple unconventional myosin domains of the intestinal brush border cytoskeleton.

  1994cited by this paper
• Golgi-derived vesicles from developing epithelial cells bind actin filaments and possess myosin-I as a cytoplasmically oriented peripheral membrane protein

  1993cited by this paper
• Toxigenic diarrheas, congenital diarrheas, and cystic fibrosis: disorders of intestinal ion transport.

  1993cited by this paper
• Assembly of the brush border cytoskeleton: changes in the distribution of microvillar core proteins during enterocyte differentiation in adult chicken intestine.

  1990cited by this paper
• Demonstration of microtubules in the terminal web of mature absorptive cells from the small intestine of the rat

  1987cited by this paper
• Brush border cytoskeleton and integration of cellular functions

  1984cited by this paper
• Mechanism of brush border contractility studied by the quick-freeze, deep-etch method

  1983cited by this paper
• Gastrointestinal manifestations of cystic fibrosis: a review.

  1981cited by this paper
• Characterization and localization of myosin in the brush border of intestinal epithelial cells

  1978cited by this paper
• Tropomyosin from bovine brain contains two polypeptide chains of slightly different molecular weights

  1978cited by this paper
• Brush border motility. Microvillar contraction in triton-treated brush borders isolated from intestinal epithelium

  1976cited by this paper

• Distinct Roles of SLC26A3 and CFTR in Surface pH Regulation and Bicarbonate Secretion in Human Intestinal Epithelium

  2026cites this paper
• CFTR High Expresser BEST4+ cells are pH-sensing neuropod cells: new implications for intestinal physiology and Cystic Fibrosis disease

  2025cites this paper
• CFTR High Expresser BEST4+ cells are pH-sensing neuropod cells: new implications for intestinal physiology and Cystic Fibrosis disease.

  2025cites this paper
• Disulfidptosis and Its Hub Gene Slc3a2 Involved in Ulcerative Colitis Pathogenesis, Disease Progression, and Patient Responses to Biologic Therapies

  2024cites this paper
• Localization and function of humanized F508del-CFTR in mouse intestine following activation of Serum Glucocorticoid kinase 1 and Trikafta.

  2024cites this paper
• Myosin 1e deficiency affects migration of 4T1 breast cancer cells

  2023cites this paper
• Gut microbiota promotes pain chronicity in Myosin1A deficient male mice

  2023influential citation
• CFTR High Expresser Cells in cystic fibrosis and intestinal diseases

  2023cites this paper
• Enhanced ileum function in weaned piglets via Laminaria digitata and alginate lyase dietary inclusion: A combined proteomics and metabolomics analysis.

  2023cites this paper
• Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces.

  2022cites this paper
• Myosins and membrane trafficking in intestinal brush border assembly.

  2022cites this paper
• Intestinal secretory mechanisms and diarrhea.

  2022cites this paper
• Intestinal brush border assembly during the peri-hatch period and its contribution to surface area expansion

  2021cites this paper
• Secretory Diarrhea

  2020cites this paper
• Myosins and Disease.

  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016influential citation
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015influential citation
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2013cites this paper
• Characterization of CFTR High Expresser cells in the intestine.

  2013influential citation
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• Regulated traffic of anion transporters in mammalian Brunner's glands: a role for water and fluid transport.

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