Epstein‐Barr Virus and Posttransplant Lymphoproliferative Disorder in Solid Organ Transplant Recipients

Posttransplant lymphoproliferative disorder (PTLD) is recognized as potentially one of the most devastating complications of organ transplantation. Epstein-Barr virus (EBV) is associated with the majority of PTLD cases. The entity referred to as EBV-associated PTLD encompasses a wide spectrum of clinical conditions characterized by lymphoproliferation after transplantation. These syndromes range from uncomplicated infectious mononucleosis to true malignancies (1–3). Disease may be nodal or extranodal, localized, often in the allograft, or widely disseminated. Patients may be symptomatic or asymptomatic. PTLD may resemble a self-limited infection or be indistinguishable from non-Hodgkin’s lymphoma. Lesions may be localized and progress slowly or the patient may present with a fulminant multisystem sepsis-like syndrome.

• Publication year

  2009

• Venue

  American Journal of Transplantation

• Publication date

  2009-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/j.1600-6143.2009.02898.xPMID 20070701
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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