SCIENCE@home

Types of neural guides and using nanotechnology for peripheral nerve reconstruction

E. Biazar,Mt Khorasani,N. Montazeri,K. Pourshamsian,M. Daliri,M. T,Mahmoud Jabarvand B,A. Khoshzaban,Saeed Heidari K,M. Jafarpour,Ziba Roviemiab

Published 2010 in International Journal of Nanomedicine

ABSTRACT

Peripheral nerve injuries can lead to lifetime loss of function and permanent disfigurement. Different methods, such as conventional allograft procedures and use of biologic tubes present problems when used for damaged peripheral nerve reconstruction. Designed scaffolds comprised of natural and synthetic materials are now widely used in the reconstruction of damaged tissues. Utilization of absorbable and nonabsorbable synthetic and natural polymers with unique characteristics can be an appropriate solution to repair damaged nerve tissues. Polymeric nanofibrous scaffolds with properties similar to neural structures can be more effective in the reconstruction process. Better cell adhesion and migration, more guiding of axons, and structural features, such as porosity, provide a clearer role for nanofibers in the restoration of neural tissues. In this paper, basic concepts of peripheral nerve injury, types of artificial and natural guides, and methods to improve the performance of tubes, such as orientation, nanotechnology applications for nerve reconstruction, fibers and nanofibers, electrospinning methods, and their application in peripheral nerve reconstruction are reviewed.

PUBLICATION RECORD

CITATION MAP

EXTRACTION MAP

CLAIMS

  • No claims are published for this paper.

CONCEPTS

  • No concepts are published for this paper.

REFERENCES

Showing 1-89 of 89 references · Page 1 of 1

CITED BY

Showing 1-100 of 119 citing papers · Page 1 of 2

12
Next