Uptake, Time Course, and Predictors of Risk-Reducing Surgeries in BRCA Carriers

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Genetic Testing and Molecular Biomarkers

• Publication date

  2009-01-08

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/gtmb.2008.0067PMID 19309274PMCID PMC2981359
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers

  2008influential reference
• A Prospective Study of Risk-Reducing Salpingo-oophorectomy and Longitudinal CA-125 Screening among Women at Increased Genetic Risk of Ovarian Cancer: Design and Baseline Characteristics: A Gynecologic Oncology Group Study

  2008cited by this paper
• Clinical practice. Management of an inherited predisposition to breast cancer.

  2007cited by this paper
• Effectiveness of preventive interventions in BRCA1/2 gene mutation carriers: A systematic review

  2007cited by this paper
• Limited family structure and BRCA gene mutation status in single cases of breast cancer.

  2007cited by this paper
• Prophylactic Bilateral Salpingo-Oophorectomy Compared With Surveillance in Women With BRCA Mutations

  2006influential reference
• Acceptance of Preventive Surgeries by Israeli Women Who had Undergone BRCA Testing

  2006influential reference
• Cost-Effectiveness of Preventive Strategies for Women with a BRCA1 or a BRCA2 Mutation

  2006cited by this paper
• Ovarian carcinoma screening in women at intermediate risk

  2005cited by this paper
• Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility: Systematic Evidence Review for the U.S. Preventive Services Task Force

  2005influential reference
• Recruitment, Genetic Counseling, and BRCA Testing for Underserved Women at a Public Hospital

  2005influential reference
• Risk-reducing salpingo-oophorectomy in BRCA mutation carriers: role of serial sectioning in the detection of occult malignancy.

  2005cited by this paper
• Utilization of screening and preventive surgery among unaffected carriers of a BRCA1 or BRCA2 gene mutation.

  2004influential reference
• STUDENTJAMA. Preparing for personalized medicine.

  2004cited by this paper
• Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group.

  2004cited by this paper
• Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies.

  2003cited by this paper
• Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2

  2003cited by this paper
• Genetic testing for a BRCA1 mutation: Prophylactic surgery and screening behavior in women 2 years post testing

  2003influential reference
• Bilateral prophylactic oophorectomy and ovarian cancer screening following BRCA1/BRCA2 mutation testing.

  2003influential reference
• Potential for bias in studies on efficacy of prophylactic surgery for BRCA1 and BRCA2 mutation.

  2003cited by this paper
• Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations.

  2002cited by this paper
• Effect of prevention strategies on survival and quality-adjusted survival of women with BRCA1/2 mutations: an updated decision analysis.

  2002influential reference
• One Year Follow-Up of Women Opting for Presymptomatic Testing for BRCA1 and BRCA2: Emotional Impact of the Test Outcome and Decisions on Risk Management (Surveillance or Prophylactic Surgery)

  2002influential reference
• Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation.

  2002influential reference
• Insurance reimbursement for risk-reducing mastectomy and oophorectomy in women with BRCA1 or BRCA2 mutations

  2001cited by this paper
• Incidence of Second Primary Breast Cancer Among Women with a First Primary in Manitoba, Canada

  2001cited by this paper
• Tamoxifen and breast cancer incidence among women with inherited mutations in BRCA1 and BRCA2: National Surgical Adjuvant Breast and Bowel Project (NSABP-P1) Breast Cancer Prevention Trial.

  2001cited by this paper
• Women's attitudes toward preventive strategies for hereditary breast or ovarian carcinoma differ from one country to another

  2001cited by this paper
• Prophylactic surgery decisions and surveillance practices one year following BRCA1/2 testing.

  2000influential reference
• Prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers.

  2000influential reference
• Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.

  1998cited by this paper
• Prevalence and contribution of BRCA1 mutations in breast cancer and ovarian cancer: results from three U.S. population-based case-control studies of ovarian cancer.

  1997cited by this paper
• Founder BRCA1 and BRCA2 mutations in Ashkenazi Jews in Israel: frequency and differential penetrance in ovarian cancer and in breast-ovarian cancer families.

  1997cited by this paper
• Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.

  1994cited by this paper
• A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.

  1994cited by this paper
• Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.

  1994cited by this paper

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  2026cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2023cites this paper
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  2023cites this paper
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  2022cites this paper
• Attitude towards hereditary cancer risk management among women with cancer in Taiwan

  2022cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
• Uptake and efficacy of bilateral risk reducing surgery in unaffected female BRCA1 and BRCA2 carriers

  2021cites this paper
• Effect of risk-reducing salpingo-oophorectomy on quality of life in Korean BRCA mutation carriers.

  2021cites this paper
• Trends and timing of risk-reducing mastectomy uptake in unaffected BRCA1 and BRCA2 carriers in Slovenia.

  2021cites this paper
• Uptake and timing of risk-reducing salpingo-oophorectomy among patients with BRCA1/2 mutations.

  2021cites this paper
• Uptake of bilateral-risk-reducing-mastectomy: Prospective analysis of 7195 women at high-risk of breast cancer

  2021influential citation
• Healthcare Utilization and Costs after Receiving a Positive BRCA1/2 Result from a Genomic Screening Program

  2020cites this paper
• Systematic review of acceptability, cardiovascular, neurological, bone health and HRT outcomes following risk reducing surgery in BRCA carriers.

  2020cites this paper
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  2020cites this paper
• Attitudes towards risk-reducing early salpingectomy with delayed oophorectomy for ovarian cancer prevention: a cohort study

  2020cites this paper
• Facilitated cascade testing (FaCT): a randomized controlled trial

  2020cites this paper
• Factors associated with the decision to undergo risk-reducing salpingo-oophorectomy among women at high risk for hereditary breast and ovarian cancer: a systematic review

  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017influential citation
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  2017influential citation
• Cancer Risk-Reducing Opportunities in Gynecologic Surgery.

  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2015influential citation
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2014cites this paper
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  2014cites this paper
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