Serotonergic anxiolytics and treatment of depression.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Psychopathology

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1159/000284624PMID 2657837
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A 5-HT1A ligand with both antidepressant and anxiolytic properties.

  1988cited by this paper
• Buspirone, a new approach to the treatment of anxiety

  1988cited by this paper
• Reversal of helpless behavior in rats by putative 5-HT1A agonists.

  1988cited by this paper
• Potential antidepressant properties of 8-hydroxy-2-(di-n-propylamino)tetralin, a selective serotonin1A receptor agonist.

  1987cited by this paper
• Modification of 5‐HT neuron properties by sustained administration of the 5‐HT1A agonist gepirone: Electrophysiological studies in the rat brain

  1987cited by this paper
• Open trial of buspirone in the treatment of major depressive disorder.

  1986cited by this paper
• Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. I. Enhanced response in depression and mania.

  1984cited by this paper
• Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. II. Relation to suicide, psychosis, and depressive symptoms.

  1984cited by this paper
• Phenelzine v imipramine in atypical depression. A preliminary report.

  1984cited by this paper
• A double-blind comparison of buspirone and diazepam in outpatients with generalized anxiety disorder.

  1982cited by this paper
• The comparative efficacy of buspirone and diazepam in the treatment of anxiety.

  1979cited by this paper
• The assessment of anxiety states by rating.

  1959cited by this paper

• Anxiolytic and Antidepressant Potential of Methanolic Extract of Neurada procumbens Linn. in Mice

  2023cites this paper
• The activity of the serotonergic 5-HT1A receptor is modulated by voltage and sodium levels

  2022cites this paper
• 5-HT1A receptor: Role in the regulation of different types of behavior

  2017influential citation
• Sex and Pharmacological Sexual Enhancement

  2017cites this paper
• Selective Modulation of K+ Channel Kv7.4 Significantly Affects the Excitability of DRN 5-HT Neurons

  2017cites this paper
• 5-HT1A Autoreceptors in the Dorsal Raphe Nucleus Convey Vulnerability to Compulsive Cocaine Seeking

  2016cites this paper
• 5-HT1А рецептор: роль в регуляции различных видов поведения

  2016cites this paper
• Running title: The role of 5-HT1A autoreceptors in cocaine addiction

  2015cites this paper
• Effect of fluoxetine and resveratrol on testicular functions and oxidative stress in a rat model of chronic mild stress-induced depression.

  2015cites this paper
• 5-HT1A receptor as a key player in the brain 5-HT system

  2013cites this paper
• Acute and subchronic effects of buspirone on attention and impulsivity in the five-choice serial reaction time task in rats.

  2013cites this paper
• Polymorphism of Serotonin 5-HT Receptors as the Basis of the Multifunctionality of Serotonin

  2012cites this paper
• 5-HT1A Partial Agonists

  2012cites this paper
• Efficacy of adjunctive aripiprazole in patients with major depressive disorder who showed minimal response to initial antidepressant therapy

  2012cites this paper
• Stress-Hyperresponsive WKY Rats Demonstrate Depressed Dorsal Raphe Neuronal Excitability and Dysregulated CRF-Mediated Responses

  2011cites this paper
• Receptor-genes cross-talk: effect of chronic 5-HT(1A) agonist 8-hydroxy-2-(di-n-propylamino) tetralin treatment on the expression of key genes in brain serotonin system and on behavior.

  2010cites this paper
• On the role of the selective silencer Freud-1 in the regulation of the brain 5-HT1A receptor gene expression

  2010cites this paper
• The Combination of Buspirone and Bupropion in the Treatment of Depression

  2007cites this paper
• In vitro characterization of SLV308 (7‐[4‐methyl‐1‐piperazinyl]‐2(3H)‐benzoxazolone, monohydrochloride): A novel partial dopamine D2 and D3 receptor agonist and serotonin 5‐HT1A receptor agonist

  2006cites this paper
• Do Antidepressants Cure or Create Abnormal Brain States?

  2006cites this paper
• Quantitative assay of 5-HT1A receptor gene expression in the brain

  2006cites this paper
• [Quantitative assay of 5-HT(1A) serotonin receptor gene expression in the brain].

  2006cites this paper
• Effects of salbutamol upon performance on an operant screen for antidepressants

  2005cites this paper
• 1-(2-Pyrimidinyl)-piperazine may alter the effects of the 5-HT1A agonists in the learned helplessness paradigm in rats

  2005cites this paper
• Effects of repeated treatment with 5-HT1A agonists on active avoidance responding in the rat

  2005cites this paper
• ["DISCOVERING THE MOLECULAR AND CELLULAR MECHANISMS UNDERLYING FENFLURAMINE-INDUCED CARDIOPULMONARY SIDE EFFECTS"]

  2005cites this paper
• Antidepressant-like effects of SR 57227A, a 5-HT3 receptor agonist, in rodents

  2005cites this paper
• Effects of acute and chronic buspirone on impulsive choice and efflux of 5-HT and dopamine in hippocampus, nucleus accumbens and prefrontal cortex

  2004cites this paper
• SSR181507, A Dopamine D2 Receptor Antagonist and 5-HT1A Receptor Agonist. I: Neurochemical and Electrophysiological Profile

  2003cites this paper
• Neonatal treatment with fluoxetine reduces depressive behavior induced by forced swim in adult rats.

  2002cites this paper
• On the quantification of [18F]MPPF binding to 5-HT1A receptors in the human brain.

  2001cites this paper
• Quantifying drug-related 5-HT1A receptor occupancy with [18F]MPPF

  2001cites this paper
• In vivo delineation of 5-HT1A receptors in human brain with [18F]MPPF.

  2000cites this paper
• Long-term fluoxetine produces behavioral anxiolytic effects without inhibiting neuroendocrine responses to conditioned stress in rats.

  2000cites this paper
• Fulminant Hepatocyte Apoptosis In Vivo Following Microcystin-LR Administration to Rats

  2000cites this paper
• Serotonergic drugs in the treatment of depressive and anxiety disorders

  2000cites this paper
• Toxicology and risk assessment of freshwater cyanobacterial (blue-green algal) toxins in water.

  2000cites this paper
• Quantitative imaging of 5-HT(1A) receptor binding in healthy volunteers with [(18)f]p-MPPF.

  2000cites this paper
• Augmentation of Antidepressant Pharmacotherapy: A Preclinical Approach Using the Mouse Forced Swimming Test

  1999cites this paper
• Anxiolytics, adrenergic agents, and naltrexone.

  1999cites this paper
• Effects of the 5-HT1A receptor agonist 8-OH-DPAT on operant food intake in food-deprived pigs.

  1999cites this paper
• Where Structure Meets Function

  1998cites this paper
• Buspirone and lorazepam in the treatment of generalized anxiety disorder in outpatients

  1998cites this paper
• Structure Activity Relationship of Homochiral 7‐Substituted 1‐Aminoindans as 5‐HT1A Receptor Ligands

  1998cites this paper
• 5-HT1A receptor-mediated inhibition of nucleus accumbens neurons activated by stimulation of parafascicular nucleus of thalamus

  1998influential citation
• 5-Hydroxytryptamine2-family receptors (5-hydroxytryptamine2A, 5-hydroxytryptamine2B, 5-hydroxytryptamine2C): where structure meets function.

  1998cites this paper
• Antidepressant-like effects of alnespirone (S 20499) in the learned helplessness test in rats.

  1998cites this paper
• Dose-dependent influence of buspirone on the activities of selective serotonin reuptake inhibitors in the mouse forced swimming test

  1998cites this paper
• Effectiveness of ipsapirone, a 5-HT-1A partial agonist, in major depressive disorder: support for the role of 5-HT-1A receptors in the mechanism of action of serotonergic antidepressants.

  1998cites this paper
• Buspirone and imipramine for the treatment of major depression in the elderly.

  1998cites this paper
• Development of new antidepressants.

  1997cites this paper
• Modification of hypothalamic-pituitary-adrenocortical activity by serotonergic agents in the rat.

  1997cites this paper
• Actions of serotonergic agents on hypothalamic-pituitary-adrenal axis activity in the rat.

  1997cites this paper
• 1192U90 in Animal Tests That Predict Antipsychotic Efficacy, Anxiolysis, and Extrapyramidal Side Effects

  1996cites this paper
• Behavioral effects of HT-90B, a putative novel anxiolytic agent with potent antidepressive activity.

  1996cites this paper
• Lack of 5-hydroxytryptamine1A-mediated inhibition of adenylyl cyclase in dorsal raphe of male and female rats.

  1996cites this paper
• Circadian rhythms and the pharmacology of affective illness.

  1996cites this paper
• Effects of 8-OH-DPAT on corticosterone after acute and chronic administration of antidepressants.

  1995cites this paper
• Chronic buspirone treatment differentially regulates 5-HT1A and 5-HT2A receptor mRNA and binding sites in various regions of the rat hippocampus.

  1995cites this paper
• Regulation of central 5-HT2A receptors: a review of in vivo studies.

  1995cites this paper
• Chemisch neuartige Tranquilizer und Hypnotika

  1995cites this paper
• Drug‐induced defaecation in rats: role of central 5‐HT1A receptors

  1995cites this paper
• Overlap of buspirone with lorazepam, diazepam and bromazepam in patients with generalized anxiety disorder: Findings from a controlled, multicentre, double‐blind study

  1994cites this paper
• Gepirone in Depression and Anxiety Disorders An Initial Appraisal of its Clinical Potential

  1994cites this paper
• [The current concepts of the phenomenology, pathogenesis and therapy of anxiety states].

  1994cites this paper
• Differential induction of 5-HT1A-mediated responses in vivo by three chemically dissimilar 5-HT1A agonists.

  1994cites this paper
• The acute effects of nefazodone, trazodone and buspirone on sleep and sleep-related penile tumescence in normal subjects.

  1994cites this paper
• Gepirone in Depression and Anxiety Disorders

  1994cites this paper
• Approaches to developing new anxiolytics and antidepressants.

  1993cites this paper
• A placebo‐controlled double‐blind multicenter trial of two doses of ipsapirone versus diazepam in generalized anxiety disorder

  1993cites this paper
• The antinociceptive efficacy of typical and atypical antidepressant compounds: Further evidence of serotonergic function in analgesia

  1993cites this paper
• Fluorescent probes for 5-HT1A receptors: Synthesis and characterization of 5-methoxy-3-[n-propyl(4-n-aminobutyl)] amino-3,4-dihydro-2H-1-benzopyran derivatives

  1993cites this paper
• Serotonin related functions in panic-anxiety: a critical overview.

  1992cites this paper
• Domestication alters 5-HT1A receptor binding in rat brain.

  1992cites this paper
• The future of 5-HT1A receptor agonists. (Aryl-piperazine derivatives).

  1992cites this paper
• 5-Hydroxytryptamine1A receptor agonists in animal models of depression and anxiety.

  1992cites this paper
• Endocrine and receptor pharmacology of serotonergic anxiolytics, antipsychotics and antidepressants.

  1992cites this paper
• Stress, anxiety, and depression: Review of biological, diagnostic, and nosologic issues

  1992cites this paper
• About the centrality of mood lowering in mood disorders. Plenary Lecture ECNP Congress, Monte Carlo, October 1991.

  1992cites this paper
• 5-Hydroxytryptamine receptors.

  1992cites this paper
• About the centrality of mood lowering in mood disorders. Plenary Lecture ECNP Congress, Monte Carlo, October 1991.

  1992cites this paper
• Chapter 3. Advances in Central Serotoninergics

  1992cites this paper
• S 14671: a naphtylpiperazine 5-hydroxytryptamine1A agonist of exceptional potency and high efficacy possessing antagonist activity at 5-hydroxytryptamine1C/2 receptors.

  1992cites this paper
• Clinical and biochemical aspects of depressive disorders: II. Transmitter/receptor theories

  1991cites this paper
• Antidepressant-like effects of buspirone mediated by the 5-HT1A post-synaptic receptors in the learned helplessness paradigm.

  1991cites this paper
• 5-HT1A partial agonists. What is their future?

  1991cites this paper
• A quantitative interresponse-time analysis of DRL performance differentiates similar effects of the antidepressant desipramine and the novel anxiolytic gepirone.

  1991cites this paper
• Possible augmentation of antidepressant response by buspirone.

  1991cites this paper
• Acute administration of diazepam and buspirone in rats trained on conflict schedules having different degrees of predictability.

  1991cites this paper
• Controlled comparison of buspirone and clomipramine in obsessive-compulsive disorder.

  1991cites this paper
• Serotonin-selective arylpiperazines with neuroendocrine, behavioral, temperature, and cardiovascular effects in humans.

  1991cites this paper
• Buspirone: sedative or stimulant effect?

  1991cites this paper
• Pharmacological Models of Depression

  1991cites this paper
• Molecular basis of buspirone's anxiolytic action.

  1991cites this paper
• Chronic administration of buspirone down‐regulates 5‐HT2 receptor binding sites

  1991cites this paper
• Chapter 3. Progress in Antidepressant Drugs

  1991cites this paper
• Corticosterone response to 8-OH-DPAT after chronic administration of antidepressants.

  1991cites this paper
• C8-substituted derivatives of 2-(dipropylamino)tetralin: Palladium-catalyzed synthesis and interactions with 5-HT1A-receptors

  1991cites this paper
• Proceedings for the 7th Workshop for the Biochemical and Pharmacological Research on Affective Disorders

  1991cites this paper
• An open trial of buspirone added to neuroleptics in schizophrenic patients.

  1991cites this paper