Biosynthesis and Use of Cobalamin (B12)

No abstract is available for this paper.

• Publication year

  2008

• Venue

  EcoSal Plus

• Publication date

  2008-08-05

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1128/ecosalplus.3.6.3.8PMID 26443728
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Crystal structures of CbiL, a methyltransferase involved in anaerobic vitamin B12 biosynthesis, and CbiL in complex with S‐adenosylhomocysteine − implications for the reaction mechanism

  2007cited by this paper
• Structural Characterization of the Active Site of the PduO-Type ATP:Co(I)rrinoid Adenosyltransferase from Lactobacillus reuteri*

  2007cited by this paper
• Elucidation of Substrate Specificity in the Cobalamin (Vitamin B12) Biosynthetic Methyltransferases

  2007cited by this paper
• Single-enzyme conversion of FMNH2 to 5,6-dimethylbenzimidazole, the lower ligand of B12

  2007cited by this paper
• The multiple amidation reactions catalyzed by Cobyric acid synthetase from Salmonella typhimurium are sequential and dissociative.

  2007cited by this paper
• The CbiB Protein of Salmonella enterica Is an Integral Membrane Protein Involved in the Last Step of the De Novo Corrin Ring Biosynthetic Pathway

  2007influential reference
• Reassessment of the Late Steps of Coenzyme B12 Synthesis in Salmonella enterica: Evidence that Dephosphorylation of Adenosylcobalamin-5′-Phosphate by the CobC Phosphatase Is the Last Step of the Pathway

  2007cited by this paper
• Finding the final pieces of the vitamin B12 biosynthetic jigsaw.

  2006cited by this paper
• Polyhedral organelles compartmenting bacterial metabolic processes

  2006influential reference
• Sinorhizobium meliloti bluB is necessary for production of 5,6-dimethylbenzimidazole, the lower ligand of B12.

  2006cited by this paper
• Genetically engineered synthesis and structural characterization of cobalt-precorrin 5A and -5B, two new intermediates on the anaerobic pathway to vitamin B12: definition of the roles of the CbiF and CbiG enzymes.

  2006cited by this paper
• Ultrafast excited-state dynamics in vitamin B12 and related cob(III)alamins.

  2006cited by this paper
• Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine.

  2006cited by this paper
• PduL Is an Evolutionarily Distinct Phosphotransacylase Involved in B12-Dependent 1,2-Propanediol Degradation by Salmonella enterica Serovar Typhimurium LT2

  2006cited by this paper
• Structure of Halothiobacillus neapolitanus carboxysomes by cryo-electron tomography.

  2006cited by this paper
• Synergistic, random sequential binding of substrates in cobalamin-independent methionine synthase.

  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
• The crystal structure of putative precorrin isomerase CbiC in cobalamin biosynthesis.

  2006cited by this paper
• Purification and Initial Biochemical Characterization of ATP:Cob(I)alamin Adenosyltransferase (EutT) Enzyme of Salmonella enterica*

  2006cited by this paper
• Intact Carboxysomes in a Cyanobacterial Cell Visualized by Hilbert Differential Contrast Transmission Electron Microscopy

  2006cited by this paper
• Prediction of CsrA-regulating small RNAs in bacteria and their experimental verification in Vibrio fischeri

  2006cited by this paper
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  2006cited by this paper
• Activation of methyltetrahydrofolate by cobalamin-independent methionine synthase.

  2006cited by this paper
• Signaling by the Arc Two-Component System Provides a Link Between the Redox State of the Quinone Pool and Gene Expression

  2006cited by this paper
• Comprehensive Alanine-scanning Mutagenesis of Escherichia coli CsrA Defines Two Subdomains of Critical Functional Importance*

  2006cited by this paper
• Fine-Tuning Our Knowledge of the Anaerobic Route to Cobalamin (Vitamin B12)

  2006cited by this paper
• Studies of the CobA-Type ATP:Co(I)rrinoid Adenosyltransferase Enzyme of Methanosarcina mazei Strain Gö1

  2006cited by this paper
• Structure of ATP-bound human ATP:cobalamin adenosyltransferase.

  2006cited by this paper
• Protein Structures Forming the Shell of Primitive Bacterial Organelles

  2005cited by this paper
• Chemistry and enzymology of vitamin B12.

  2005cited by this paper
• Conserved P-loop GTPases of unknown function in bacteria: an emerging and vital ensemble in bacterial physiology.

  2005cited by this paper
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  2005cited by this paper
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  2005cited by this paper
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  2005cited by this paper
• Role of the precorrin 6-X reductase gene in cobamide biosynthesis in Methanococcus maripaludis.

  2005cited by this paper
• Genetically Engineered Production of 1-Desmethylcobyrinic Acid, 1-Desmethylcobyrinic Acid a,c-Diamide, and Cobyrinic Acid a,c-Diamide in Escherichia coli Implies a Role for CbiD in C-1 Methylation in the Anaerobic Pathway to Cobalamin*

  2005cited by this paper
• Biochemical evidence that the pduS gene encodes a bifunctional cobalamin reductase.

  2005cited by this paper
• Chemistry and Enzymology of Vitamin B12

  2005cited by this paper
• Computer-assisted Docking of Flavodoxin with the ATP:Co(I)rrinoid Adenosyltransferase (CobA) Enzyme Reveals Residues Critical for Protein-Protein Interactions but Not for Catalysis*

  2005cited by this paper
• Complex Formation between Glutamyl-tRNA Reductase and Glutamate-1-semialdehyde 2,1-Aminomutase in Escherichia coli during the Initial Reactions of Porphyrin Biosynthesis*

  2005cited by this paper
• Spectroscopic and computational studies of the ATP:corrinoid adenosyltransferase (CobA) from Salmonella enterica: insights into the mechanism of adenosylcobalamin biosynthesis.

  2005cited by this paper
• Crystal structure of the hypothetical protein TA1238 from Thermoplasma acidophilum: A new type of helical super-bundle

  2005cited by this paper
• A pH-Sensitive Function and Phenotype: Evidence that EutH Facilitates Diffusion of Uncharged Ethanolamine in Salmonella enterica

  2004cited by this paper
• Inaugural Article: Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase

  2004cited by this paper
• SIR2: the biochemical mechanism of NAD(+)-dependent protein deacetylation and ADP-ribosyl enzyme intermediates.

  2004cited by this paper
• Purification and Initial Characterization of the Salmonella enterica PduO ATP:Cob(I)alamin Adenosyltransferase

  2004cited by this paper
• A Novel Evolutionary Lineage of Carbonic Anhydrase (ε Class) Is a Component of the Carboxysome Shell

  2004cited by this paper
• The eutT Gene of Salmonella enterica Encodes an Oxygen-Labile, Metal-Containing ATP:Corrinoid Adenosyltransferase Enzyme

  2004cited by this paper
• Coenzyme B12 riboswitches are widespread genetic control elements in prokaryotes.

  2004cited by this paper
• Cobalamin-Independent Methionine Synthase (MetE): A Face-to-Face Double Barrel That Evolved by Gene Duplication

  2004cited by this paper
• Oxidative Stress Inactivates Cobalamin-Independent Methionine Synthase (MetE) in Escherichia coli

  2004cited by this paper
• The last step in coenzyme B(12) synthesis is localized to the cell membrane in bacteria and archaea.

  2004cited by this paper
• Measurement of energetics of conformational change in cobalamin-dependent methionine synthase.

  2004cited by this paper
• CO2-Responsive Expression and Gene Organization of Three Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase Enzymes and Carboxysomes in Hydrogenovibrio marinus Strain MH-110

  2004cited by this paper
• Human ATP:Cob(I)alamin Adenosyltransferase and Its Interaction with Methionine Synthase Reductase*

  2004cited by this paper
• Spectroscopic and computational studies of Co2+corrinoids: spectral and electronic properties of the biologically relevant base-on and base-off forms of Co2+cobalamin.

  2004cited by this paper
• CbiZ, an amidohydrolase enzyme required for salvaging the coenzyme B12 precursor cobinamide in archaea.

  2004cited by this paper
• Structure/function studies on a S-adenosyl-L-methionine-dependent uroporphyrinogen III C methyltransferase (SUMT), a key regulatory enzyme of tetrapyrrole biosynthesis.

  2004cited by this paper
• Modulation of AraC family member activity by protein ligands

  2004cited by this paper
• The eutD Gene of Salmonella enterica Encodes a Protein with Phosphotransacetylase Enzyme Activity

  2004influential reference
• Mechanism of cobyrinic acid a,c-diamide synthetase from Salmonella typhimurium LT2.

  2004cited by this paper
• Evidence that a B12-Adenosyl Transferase Is Encoded within the Ethanolamine Operon of Salmonella enterica

  2004cited by this paper
• Identification of a Reactivating Factor for Adenosylcobalamin-Dependent Ethanolamine Ammonia Lyase

  2004cited by this paper
• α-5,6-Dimethylbenzimidazole adenine dinucleotide (α-DAD), a putative new intermediate of coenzyme B12 biosynthesis in Salmonella typhimurium

  2003cited by this paper
• The cobY Gene of the Archaeon Halobacterium sp. Strain NRC-1 Is Required for De Novo Cobamide Synthesis

  2003cited by this paper
• Formation of the dimethylbenzimidazole ligand of coenzyme B(12) under physiological conditions by a facile oxidative cascade.

  2003cited by this paper
• Factors modulating conformational equilibria in large modular proteins: A case study with cobalamin-dependent methionine synthase

  2003cited by this paper
• Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium.

  2003cited by this paper
• Cobalamin-dependent methionine synthase: probing the role of the axial base in catalysis of methyl transfer between methyltetrahydrofolate and exogenous cob(I)alamin or cob(I)inamide.

  2003cited by this paper
• Comparative Genomics of the Vitamin B12 Metabolism and Regulation in Prokaryotes*

  2003cited by this paper
• A Story of Chelatase Evolution

  2003cited by this paper
• Global regulation by CsrA in Salmonella typhimurium

  2003influential reference
• Spectroscopic and computational studies of Co3+-corrinoids: spectral and electronic properties of the B12 cofactors and biologically relevant precursors.

  2003cited by this paper
• Short-chain fatty acid activation by acyl-coenzyme A synthetases requires SIR2 protein function in Salmonella enterica and Saccharomyces cerevisiae.

  2003cited by this paper
• A New Pathway for Salvaging the CoenzymeB12 Precursor Cobinamide in Archaea RequiresCobinamide-Phosphate Synthase (CbiB) EnzymeActivity

  2003cited by this paper
• Many paths to methyltransfer: a chronicle of convergence.

  2003cited by this paper
• PduP is a coenzyme-a-acylating propionaldehyde dehydrogenase associated with the polyhedral bodies involved in B12-dependent 1,2-propanediol degradation by Salmonella enterica serovar Typhimurium LT2

  2003cited by this paper
• Propionyl Coenzyme A Is a Common Intermediate in the 1,2-Propanediol and Propionate Catabolic Pathways Needed for Expression of the prpBCDE Operon during Growth of Salmonella enterica on 1,2-Propanediol

  2003cited by this paper
• Identification of the Human and Bovine ATP:Cob(I)alamin Adenosyltransferase cDNAs Based on Complementation of a Bacterial Mutant*

  2003cited by this paper
• Protein Content of Polyhedral Organelles Involved in Coenzyme B12-Dependent Degradation of 1,2-Propanediol in Salmonella enterica Serovar Typhimurium LT2

  2003cited by this paper
• CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis

  2003cited by this paper
• The biosynthesis of adenosylcobalamin (vitamin B12).

  2002cited by this paper
• AraC-XylS database: a family of positive transcriptional regulators in bacteria

  2002influential reference
• Three-dimensional structure of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica.

  2002cited by this paper
• Capture of a Labile Substrate by Expulsion of Water Molecules from the Active Site of Nicotinate Mononucleotide:5,6-Dimethylbenzimidazole Phosphoribosyltransferase (CobT) from Salmonella enterica *

  2002cited by this paper
• Genetic control by a metabolite binding mRNA.

  2002cited by this paper
• The structure of Saccharomyces cerevisiae Met8p, a bifunctional dehydrogenase and ferrochelatase

  2002cited by this paper
• Structural studies of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica: the apo, substrate, and product-aldimine complexes.

  2002cited by this paper
• The ATP:Co(I)rrinoid Adenosyltransferase (CobA) Enzyme ofSalmonella enterica Requires the 2′-OH Group of ATP for Function and Yields Inorganic Triphosphate as Its Reaction Byproduct*

  2002cited by this paper
• Escherichia coli Glutamyl-tRNA Reductase

  2002cited by this paper
• PduA Is a Shell Protein of Polyhedral Organelles Involved in Coenzyme B12-Dependent Degradation of 1,2-Propanediol in Salmonella enterica Serovar Typhimurium LT2

  2002cited by this paper
• The crystal structure of MT0146/CbiT suggests that the putative precorrin-8w decarboxylase is a methyltransferase.

  2002cited by this paper
• Providing a chemical basis toward understanding the histidine base-on motif of methylcobalamin-dependent methionine synthase: an improved purification of methylcobinamide, plus thermodynamic studies of methylcobinamide binding exogenous imidazole and pyridine bases.

  2002cited by this paper
• Classification and evolution of P-loop GTPases and related ATPases.

  2002influential reference
• Sir2-Dependent Activation of Acetyl-CoA Synthetase by Deacetylation of Active Lysine

  2002cited by this paper
• Domain alternation switches B12-dependent methionine synthase to the activation conformation

  2002influential reference
• In vitro conversion of propionate to pyruvate by Salmonella enterica enzymes: 2-methylcitrate dehydratase (PrpD) and aconitase Enzymes catalyze the conversion of 2-methylcitrate to 2-methylisocitrate.

  2001cited by this paper
• Cobalamin-dependent methyltransferases.

  2001cited by this paper
• Structural Investigation of the Biosynthesis of Alternative Lower Ligands for Cobamides by Nicotinate Mononucleotide: 5,6-Dimethylbenzimidazole Phosphoribosyltransferase from Salmonella enterica *

  2001cited by this paper

• Attenuated Salmonella Gallinarum strain shows increased survival in primary chicken macrophage infection.

  2025cites this paper
• Cobamide metabolism, regulation, and adaptation in Mycobacterium tuberculosis

  2025cites this paper
• New-to-nature CO2-dependent acetyl-CoA assimilation enabled by an engineered B12-dependent acyl-CoA mutase

  2024cites this paper
• Exploring the biosynthetic capacity of TsrM, a B12-dependent Radical SAM Enzyme Catalyzing Non-radical Reactions.

  2022cites this paper
• Elevated Levels of an Enzyme Involved in Coenzyme B12 Biosynthesis Kills Escherichia coli

  2022cites this paper
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  2022cites this paper
• Acinetobacter baumannii Catabolizes Ethanolamine in the Absence of a Metabolosome and Converts Cobinamide into Adenosylated Cobamides

  2022cites this paper
• Translational Frameshifting in the chlD Gene Gives a Clue to the Coevolution of the Chlorophyll and Cobalamin Biosyntheses

  2022cites this paper
• VB12Path for Accurate Metagenomic Profiling of Microbially Driven Cobalamin Synthesis Pathways

  2021cites this paper
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  2021cites this paper
• Nutritional inter-dependencies and a carbazole-dioxygenase are key elements of a bacterial consortium relying on a Sphingomonas for the degradation of the fungicide thiabendazole

  2020cites this paper
• Cobamides.

  2020cites this paper
• The B12 receptor BtuB alters the membrane integrity of Caulobacter crescentus.

  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2014cites this paper
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  2012cites this paper
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  2010cites this paper
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  2010influential citation
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  2009influential citation
• Strain 2.4.1 Rhodobacter Sphaeroides in in Vivo Analysis of Cobinamide Salvaging Supplemental Material

  2009cites this paper
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  2009cites this paper
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  2009cites this paper