Frequency of MED12 mutations in phyllodes tumors: Inverse correlation with histologic grade

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Genes, Chromosomes and Cancer

• Publication date

  2016-03-03

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/gcc.22351PMID 26856273
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• MED12 somatic mutations in fibroadenomas and phyllodes tumours of the breast

  2015influential reference
• Next-Gen Sequencing Exposes Frequent MED12 Mutations and Actionable Therapeutic Targets in Phyllodes Tumors

  2015influential reference
• Distribution of MED12 mutations in fibroadenomas and phyllodes tumors of the breast—implications for tumor biology and pathological diagnosis

  2015influential reference
• Novel MED12 gene somatic mutations in women from the Southern United States with symptomatic uterine fibroids

  2015cited by this paper
• Mutational analysis of MED12 in fibroadenomas and phyllodes tumors of the breast by means of targeted next-generation sequencing

  2015influential reference
• MED12 is frequently mutated in breast phyllodes tumours: a study of 112 cases

  2015cited by this paper
• Frequent MED12 mutations in phyllodes tumours of the breast

  2015influential reference
• MED12 exon 2 mutations in phyllodes tumors of the breast

  2015cited by this paper
• Genomic landscapes of breast fibroepithelial tumors

  2015cited by this paper
• Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma

  2014influential reference
• Fibroepithelial tumors of the breast: pathologic and immunohistochemical features and molecular mechanisms.

  2014cited by this paper
• Uterine Fibroids: Do We Deal With More Than One Disease?

  2014cited by this paper
• Integrated genomic characterization of adrenocortical carcinoma

  2014cited by this paper
• MED12 exon 2 mutations in uterine and extrauterine smooth muscle tumors.

  2014influential reference
• Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.

  2014cited by this paper
• MED12 mutations in leiomyosarcoma and extrauterine leiomyoma

  2013influential reference
• Mediator complex subunit 12 exon 2 mutation analysis in different subtypes of smooth muscle tumors confirms genetic heterogeneity.

  2013cited by this paper
• Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

  2012influential reference
• WHO classification of tumours of the breast

  2012influential reference
• Mutational analysis of MED12 exon 2 in uterine leiomyoma and other common tumors

  2012cited by this paper
• MED12 Alterations in Both Human Benign and Malignant Uterine Soft Tissue Tumors

  2012influential reference
• Somatic MED12 mutations in uterine leiomyosarcoma and colorectal cancer

  2012influential reference
• Immunohistochemical and Molecular Markers in Breast Phyllodes Tumors

  2011influential reference
• Molecular classification of breast phyllodes tumors: validation of the histologic grading scheme and insights into malignant progression

  2011influential reference
• MED12, the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas

  2011influential reference
• The human Mediator complex: a versatile, genome-wide regulator of transcription.

  2010cited by this paper
• Molecular pathogenesis of progression and recurrence in breast phyllodes tumors.

  2009cited by this paper

• CCL19 and CCR6 as diagnostic biomarkers for differentiating phyllodes tumors from breast fibroadenomas: a machine learning-driven approach integrating EMT biology.

  2026cites this paper
• Molecular pathology of phyllodes tumours of the breast-much more than MED12.

  2026cites this paper
• A Comparative Study on Copy Number Variation in Subtypes of Breast Phyllodes Tumors

  2025influential citation
• Fibroepithelial Lesions: An Update for Daily Practice (Part-II).

  2025cites this paper
• Integrating single‐cell and spatial transcriptomes reveals COL4A1/2 facilitates the spatial organisation of stromal cells differentiation in breast phyllodes tumours

  2024cites this paper
• Epithelial to mesenchymal transition (EMT) in metaplastic breast cancer and phyllodes breast tumors

  2023cites this paper
• Refining the classification of breast phyllodes tumours.

  2023cites this paper
• High-Grade Spindle Cell Lesions of the Breast: Key Pathologic and Clinical Updates.

  2022cites this paper
• An integrative approach for exploring the nature of fibroepithelial neoplasms

  2022cites this paper
• Lymph Node and Distant Metastases in Phyllodes Tumor of the Breast

  2022cites this paper
• Genomic characteristics of two breast malignant phyllodes tumors during pregnancy and lactation identified through whole-exome sequencing

  2022cites this paper
• SETD2 alterations and histone H3K36 trimethylation in phyllodes tumor of breast

  2021cites this paper
• Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing

  2021cites this paper
• Fibroepithelial tumours of the breast—a review

  2021cites this paper
• Histopathologic, immunophenotypic, and proteomics characteristics of low-grade phyllodes tumor and fibroadenoma: more similarities than differences

  2020cites this paper
• New Advances in Molecular Breast Cancer Pathology.

  2020cites this paper
• Genotype‐phenotype associations in breast pathology: Achievements of the past quarter century

  2020cites this paper
• Fibroepithelial lesions revisited: implications for diagnosis and management

  2020cites this paper
• Histopathologic, immunophenotypic, and proteomics characteristics of low-grade phyllodes tumor and fibroadenoma: more similarities than differences

  2020cites this paper
• Genomic characterisation of breast fibroepithelial lesions in an international cohort

  2019cites this paper
• MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours

  2018cites this paper
• Comprehensive screening for MED12 mutations in gynaecological mesenchymal tumours identified morphologically distinctive mixed epithelial and stromal tumours

  2017cites this paper
• Genetic and Clinical Characteristics of Phyllodes Tumors of the Breast

  2017cites this paper
• Fibroepithelial lesions; The WHO spectrum.

  2017cites this paper
• Genetic analysis of uterine adenosarcomas and phyllodes tumors of the breast

  2017cites this paper
• Atypical Distant Metastasis of Breast Malignant Phyllodes Tumors: A Case Report and Literature Review

  2017cites this paper
• Comprehensive genomic profiling of malignant phyllodes tumors of the breast

  2017cites this paper
• MED12 protein expression in breast fibroepithelial lesions: correlation with mutation status and oestrogen receptor expression

  2016cites this paper
• Molecular classification of uterine leiomyomas by genome-wide methods

  2016cites this paper
• THE ROLE OF MED 12 IN TUMORIGENESIS

  2016influential citation