Acinar origin of CFTR-dependent airway submucosal gland fluid secretion.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  American Journal of Physiology - Lung cellular and Molecular Physiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPLUNG.00286.2006PMID 16997881
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Functional interaction of CFTR and ENaC in sweat glands

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• Hyposecretion, Not Hyperabsorption, Is the Basic Defect of Cystic Fibrosis Airway Glands*♦

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• Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis.

  2006cited by this paper
• Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia.

  2005influential reference
• Lysozyme secretion by submucosal glands protects the airway from bacterial infection.

  2005cited by this paper
• Submucosal gland dysfunction as a primary defect in cystic fibrosis

  2005cited by this paper
• Mechanisms of bicarbonate secretion in the pancreatic duct.

  2005cited by this paper
• A small molecule CFTR inhibitor produces cystic fibrosis‐like submucosal gland fluid secretions in normal airways

  2004cited by this paper
• Local regulation of cystic fibrosis transmembrane regulator and epithelial sodium channel in airway epithelium.

  2004cited by this paper
• Submucosal glands and airway defense.

  2004cited by this paper
• Mucus Secretion from Single Submucosal Glands of Pig

  2002cited by this paper
• Mucus clearance as a primary innate defense mechanism for mammalian airways.

  2002cited by this paper
• Absent Secretion to Vasoactive Intestinal Peptide in Cystic Fibrosis Airway Glands*

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• Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients.

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  2001cited by this paper
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  2001cited by this paper
• HCO3- transport in relation to mucus secretion from submucosal glands.

  2001cited by this paper
• CFTR, MDR1, and MRP1 Immunolocalization in Normal Human Nasal Respiratory Mucosa

  2000cited by this paper
• The genesis of cystic fibrosis lung disease.

  1999cited by this paper
• Activation of the epithelial Na+ channel (ENaC) requires CFTR Cl- channel function

  1999cited by this paper
• In situ visualization of bronchial submucosal glands and their secretory response to acetylcholine.

  1997cited by this paper
• Ion composition of airway surface liquid of patients with cystic fibrosis as compared with normal and disease-control subjects.

  1997cited by this paper
• CFTR as a cAMP-dependent regulator of sodium channels

  1995cited by this paper
• Localization of the cystic fibrosis transmembrane conductance regulator in airway secretory glands.

  1993cited by this paper
• Submucosal glands are the predominant site of CFTR expression in the human bronchus

  1992cited by this paper
• Localization of the cystic fibrosis transmembrane conductance regulator in pancreas.

  1991cited by this paper
• CFTR: development of high- affinity antibodies and localization in sweat gland.

  1991influential reference
• Hyposecretion of β-Adrenergically Induced Sweating in Cystic Fibrosis Heterozygotes

  1987cited by this paper
• Morphological, biochemical and secretory studies on rat pancreatic ducts maintained in tissue culture.

  1986cited by this paper
• Intercellular junctions in upper airway submucosal glands of the rat: A tracer and freeze fracture study

  1984cited by this paper
• Defective beta adrenergic response of cystic fibrosis sweat glands in vivo and in vitro.

  1984cited by this paper
• A reconstruction of the duct system and secretory tubules of the human bronchial submucosal gland

  1969cited by this paper
• Measurement of the Bronchial Mucous Gland Layer: A Diagnostic Yardstick in Chronic Bronchitis *

  1960cited by this paper
• The genesis of cystic fibrosis lung disease

  year unknowncited by this paper

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• Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs

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• PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa.

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  2020cites this paper
• Early Pathogenesis of Cystic Fibrosis Gallbladder Disease in a Porcine Model

  2020cites this paper
• Early studies of airway submucosal glands.

  2019cites this paper
• Effect of Bacteria on Airway Submucosal Glands Liquid Secretion in Swine

  2018cites this paper
• Lumacaftor alone and combined with ivacaftor: preclinical and clinical trial experience of F508del CFTR correction

  2016cites this paper
• Diagnostic Testing in Cystic Fibrosis.

  2016cites this paper
• CFTR modulator therapies in pediatric cystic fibrosis: focus on ivacaftor

  2016cites this paper
• A spatial model of fluid recycling in the airways of the lung.

  2015cites this paper
• Airway Gland Structure and Function.

  2015cites this paper
• Ca²⁺ signaling and fluid secretion by secretory cells of the airway epithelium.

  2014cites this paper
• Nasal drying during pressurised breathing

  2013cites this paper
• Contribution of α7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure

  2013cites this paper
• Barrier function of airway tract epithelium

  2013cites this paper
• Cystic fibrosis transmembrane conductance regulator modulators

  2013cites this paper
• CFTR, mucins, and mucus obstruction in cystic fibrosis.

  2012cites this paper
• Purinergic signalling in epithelial ion transport: regulation of secretion and absorption

  2011cites this paper
• Cystic fibrosis and the relationship between mucin and chloride secretion by cultures of human airway gland mucous cells.

  2011cites this paper
• CFTR and calcium-activated chloride channels in primary cultures of human airway gland cells of serous or mucous phenotype.

  2010cites this paper
• Mechanisms of Ca2+-stimulated fluid secretion by porcine bronchial submucosal gland serous acinar cells.

  2010cites this paper
• Substance P stimulates human airway submucosal gland secretion mainly via a CFTR-dependent process.

  2009cites this paper
• Search and rescue: finding ways to correct deltaF508 CFTR.

  2009cites this paper
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  2009cites this paper
• Mechanisms and Function of DUOX in Epithelia of the Lung

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• Salmeterol restores secretory functions in cystic fibrosis airway submucosal gland serous cells.

  2009cites this paper
• Adenosine receptors, cystic fibrosis, and airway hydration.

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• Lubiprostone stimulates secretion from tracheal submucosal glands of sheep, pigs, and humans.

  2009cites this paper
• Secretion by Murine Nasal Submucosal Gland Serous Acinar Cells during Ca

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• The epithelial cholinergic system of the airways

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• The porcine lung as a potential model for cystic fibrosis.

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• What have we learned from mouse models for cystic fibrosis?

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• Cystic fibrosis: a disease of vulnerability to airway surface dehydration.

  2007cites this paper
• Fluid secretion by submucosal glands of the tracheobronchial airways.

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• Too much salt, too little soda: cystic fibrosis.

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• Optical imaging of Ca2+‐evoked fluid secretion by murine nasal submucosal gland serous acinar cells

  2007cites this paper
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  year unknowncites this paper