Microtubule-Organizing Centers: Towards a Minimal Parts List.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Trends in Cell Biology

• Publication date

  2017-11-21

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.tcb.2017.10.005PMID 29173799
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Microtubule organization, dynamics and functions in differentiated cells

  2017cited by this paper
• Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells

  2017cited by this paper
• Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68

  2017cited by this paper
• A Splice Variant of Centrosomin Converts Mitochondria to Microtubule-Organizing Centers.

  2017cited by this paper
• The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin.

  2017cited by this paper
• Genes and molecular pathways underpinning ciliopathies

  2017cited by this paper
• Structural analysis of the role of TPX2 in branching microtubule nucleation

  2017cited by this paper
• MZT1 regulates microtubule nucleation by linking γTuRC assembly to adapter-mediated targeting and activation

  2017cited by this paper
• Microtubule-organizing centers: from the centrosome to non-centrosomal sites.

  2017cited by this paper
• Mitotic spindle assembly in animal cells: a fine balancing act

  2017cited by this paper
• CAMSAP3 accumulates in the pericentrosomal area and accompanies microtubule release from the centrosome via katanin

  2017cited by this paper
• Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres

  2017cited by this paper
• Loss of function of the Drosophila Ninein-related centrosomal protein Bsg25D causes mitotic defects and impairs embryonic development

  2016cited by this paper
• Nuclear alignment in myotubes requires centrosome proteins recruited by nesprin-1

  2016cited by this paper
• Nuclear alignment in myotubes requires centrosome proteins recruited by nesprin-1

  2016cited by this paper
• Molecular Pathway of Microtubule Organization at the Golgi Apparatus.

  2016cited by this paper
• Divergent regulation of functionally distinct γ-tubulin complexes during differentiation

  2016cited by this paper
• MOZART1 and γ-tubulin complex receptors are both required to turn γ-TuSC into an active microtubule nucleation template

  2016cited by this paper
• Organization of Non-centrosomal Microtubules in Epithelial Cells.

  2016cited by this paper
• The Seckel syndrome and centrosomal protein Ninein localizes asymmetrically to stem cell centrosomes but is not required for normal development, behavior, or DNA damage response in Drosophila

  2016cited by this paper
• Control of apico–basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7

  2016cited by this paper
• The Centrosome, a Multitalented Renaissance Organelle.

  2016cited by this paper
• Patronin/Shot Cortical Foci Assemble the Noncentrosomal Microtubule Array that Specifies the Drosophila Anterior-Posterior Axis

  2016cited by this paper
• Cilium assembly and disassembly

  2016cited by this paper
• Targeting of γ-tubulin complexes to microtubule organizing centers: conservation and divergence.

  2015cited by this paper
• A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.

  2015cited by this paper
• The augmin connection in the geometry of microtubule networks.

  2015cited by this paper
• The centrosome is an actin-organizing center

  2015cited by this paper
• Complementary activities of TPX2 and chTOG constitute an efficient importin-regulated microtubule nucleation module

  2015cited by this paper
• NOCA-1 functions with γ-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in C. elegans

  2015cited by this paper
• Microtubule-associated proteins control the kinetics of microtubule nucleation

  2015cited by this paper
• Reversible centriole depletion with an inhibitor of Polo-like kinase 4

  2015cited by this paper
• The centrosome and its duplication cycle.

  2015cited by this paper
• SPD-2/CEP192 and CDK Are Limiting for Microtubule-Organizing Center Function at the Centrosome.

  2015cited by this paper
• CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells

  2015cited by this paper
• Cell-cycle dependent phosphorylation of yeast pericentrin regulates γ-TuSC-mediated microtubule nucleation

  2014cited by this paper
• The centriole duplication cycle

  2014cited by this paper
• Centrosomes as signalling centres

  2014cited by this paper
• NME7 is a functional component of the γ-tubulin ring complex

  2014cited by this paper
• Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation

  2014cited by this paper
• Ring closure activates yeast γTuRC for species-specific microtubule nucleation

  2014cited by this paper
• A newly identified myomegalin isoform functions in Golgi microtubule organization and ER–Golgi transport

  2014cited by this paper
• TACC3 Protein Regulates Microtubule Nucleation by Affecting γ-Tubulin Ring Complexes*

  2014cited by this paper
• Microtubules that form the stationary lattice of muscle fibers are dynamic and nucleated at Golgi elements

  2013cited by this paper
• Kif3a interacts with Dynactin subunit p150Glued to organize centriole subdistal appendages

  2013cited by this paper
• Tubulin nucleotide status controls Sas-4-dependent pericentriolar material recruitment

  2012cited by this paper
• 3D-structured illumination microscopy provides novel insight into architecture of human centrosomes

  2012cited by this paper
• Structured illumination of the interface between centriole and peri-centriolar material

  2012cited by this paper
• Towards a molecular architecture of centriole assembly

  2012cited by this paper
• Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material

  2012cited by this paper
• Myomegalin is necessary for the formation of centrosomal and Golgi-derived microtubules

  2012cited by this paper
• The amorphous pericentriolar cloud takes shape

  2012cited by this paper
• Microtubule nucleation by γ-tubulin complexes

  2011cited by this paper
• Department of Biochemistry

  2011cited by this paper
• Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods

  2011cited by this paper
• Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein

  2011cited by this paper
• A developmentally regulated two-step process generates a noncentrosomal microtubule network in Drosophila tracheal cells.

  2010cited by this paper
• Conserved Motif of CDK5RAP2 Mediates Its Localization to Centrosomes and the Golgi Complex*

  2010cited by this paper
• Microtubule nucleation at the cis‐side of the Golgi apparatus requires AKAP450 and GM130

  2009cited by this paper
• Functional overlap of microtubule assembly factors in chromatin-promoted spindle assembly.

  2009cited by this paper
• Golgi-derived CLASP-dependent Microtubules Control Golgi Organization and Polarized Trafficking in Motile Cells

  2009cited by this paper
• A multicomponent assembly pathway contributes to the formation of acentrosomal microtubule arrays in interphase Drosophila cells.

  2008cited by this paper
• CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex.

  2008cited by this paper
• The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis.

  2008cited by this paper
• The mammalian centrosome and its functional significance

  2008cited by this paper
• Downregulation of Protein 4.1R, a Mature Centriole Protein, Disrupts Centrosomes, Alters Cell Cycle Progression, and Perturbs Mitotic Spindles and Anaphase

  2008cited by this paper
• Drosophila SPD-2 is an essential centriole component required for PCM recruitment and astral-microtubule nucleation.

  2008cited by this paper
• Centrosomal CAP350 protein stabilises microtubules associated with the Golgi complex

  2007cited by this paper
• Human Cep192 is required for mitotic centrosome and spindle assembly.

  2007cited by this paper
• Microtubule-organizing centres: a re-evaluation

  2007cited by this paper
• Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network.

  2007cited by this paper
• GCP6 binds to intermediate filaments: a novel function of keratins in the organization of microtubules in epithelial cells.

  2007cited by this paper
• NEDD1-dependent recruitment of the γ-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly

  2006cited by this paper
• GCP-WD is a γ-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation

  2006cited by this paper
• Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function

  2005cited by this paper
• A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring.

  2005cited by this paper
• Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assembly.

  2005cited by this paper
• Etude au microscope electronique de l'ultrastructure du centriole chez les vertébrés

  2005cited by this paper
• Odf2-deficient mother centrioles lack distal/subdistal appendages and the ability to generate primary cilia

  2005cited by this paper
• Golgi positioning

  2005cited by this paper
• The Drosophila pericentrin-like protein is essential for cilia/flagella function, but appears to be dispensable for mitosis

  2004cited by this paper
• Protein 4.1R regulates interphase microtubule organization at the centrosome

  2004cited by this paper
• Interaction of Cep135 with a p50 dynactin subunit in mammalian centrosomes.

  2004cited by this paper
• The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression

  2004cited by this paper
• Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes

  2004cited by this paper
• The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells.

  2003cited by this paper
• Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.

  2003cited by this paper
• Proteomic characterization of the human centrosome by protein correlation profiling

  2003cited by this paper
• Caenorhabditis elegans TAC-1 and ZYG-9 form a complex that is essential for long astral and spindle microtubules.

  2003cited by this paper
• TAC-1 and ZYG-9 form a complex that promotes microtubule assembly in C. elegans embryos.

  2003cited by this paper
• The XMAP215 homologue Stu2 at yeast spindle pole bodies regulates microtubule dynamics and anchorage

  2003cited by this paper
• SAS-4 is a C. elegans centriolar protein that controls centrosome size.

  2003cited by this paper
• The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is γ-tubulin dependent

  2002cited by this paper
• Centrosome maturation and mitotic spindle assembly in C. elegans require SPD-5, a protein with multiple coiled-coil domains.

  2002cited by this paper
• Assembly of centrosomal proteins and microtubule organization depends on PCM-1

  2002cited by this paper
• Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.

  2002cited by this paper
• XMAP215 is required for the microtubule-nucleating activity of centrosomes.

  2002cited by this paper
• Spindle Dynamics and the Role of γ-Tubulin in Early Caenorhabditis elegans Embryos

  2001cited by this paper
• Spindle dynamics and the role of gamma-tubulin in early Caenorhabditis elegans embryos.

  2001cited by this paper
• Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour

  2001cited by this paper

• McIdas localizes to centrioles and controls centriole numbers through PLK4-dependent phosphorylation.

  2026cites this paper
• Insights into Microtubule Nucleation at the Golgi Apparatus.

  2026cites this paper
• Microtubule nucleation at the Golgi-related membrane organelles of mouse neurons

  2025cites this paper
• Bioinformatics analysis reveals the diagnostic and therapeutic value of the centrosome replication-related gene SPICE1 in keloid.

  2025cites this paper
• Asymmetric microtubule nucleation from Golgi stacks promotes opposite microtubule polarity in axons and dendrites.

  2025cites this paper
• Diversity of microtubule arrays in animal cells at a glance.

  2025cites this paper
• eIF2A regulates cell migration in a translation-independent manner

  2025cites this paper
• CDK5RAP2 activates microtubule nucleator γTuRC by facilitating template formation and actin release.

  2024cites this paper
• Analysis of Microtubule Polymerization During Axon Outgrowth Using Fluorescently Labeled Microtubule Plus-End Tracking Proteins.

  2024cites this paper
• Structure of the native γ-tubulin ring complex capping spindle microtubules

  2024cites this paper
• TonEBP degradation is essential for microtubule nucleation and regrowth.

  2024cites this paper
• Ninein domains required for its localization, association with partners dynein and ensconsin, and microtubule organization

  2023cites this paper
• Organization of cortical microtubules in differentiated cells

  2023cites this paper
• Microtubule nucleation and γTuRC centrosome localization in interphase cells require ch-TOG

  2023cites this paper
• The AP-2 complex interacts with γ-TuRC and regulates the proliferative capacity of neural progenitors

  2023cites this paper
• Generation of stable microtubule superstructures by binding of peptide-fused tetrameric proteins to inside and outside

  2022cites this paper
• Aster repulsion drives short-ranged ordering in the Drosophila syncytial blastoderm.

  2022cites this paper
• ENKD1 is a centrosomal and ciliary microtubule‐associated protein important for primary cilium content regulation

  2022cites this paper
• MCC is a centrosomal protein that relocalizes to non-centrosomal apical sites during intestinal cell differentiation.

  2022cites this paper
• McIdas localizes at centrioles and controls centriole numbers through PLK4-dependent phosphorylation

  2022cites this paper
• The centrosomal recruitment of γ-tubulin and its microtubule nucleation activity is α-fodrin guided

  2022cites this paper
• γ-Tubulin in microtubule nucleation and beyond

  2022cites this paper
• Trip13 Depletion in Liver Cancer Induces a Lipogenic Response Contributing to Plin2‐Dependent Mitotic Cell Death

  2022cites this paper
• The cytoplasmic microtubule array in Neurospora crassa depends on microtubule-organizing centers at spindle pole bodies and microtubule +end-depending pseudo-MTOCs at septa.

  2022cites this paper
• The Reduction in Microtubule Arrays Caused by the Dysplasia of the Non-Centrosomal Microtubule-Organizing Center Leads to a Malformed Organ of Corti in the Cx26-Null Mouse

  2022cites this paper
• Understudied proteins: opportunities and challenges for functional proteomics

  2022cites this paper
• Frequent Spindle Assembly Errors Require Structural Rearrangement to Complete Meiosis in Zea mays

  2022cites this paper
• ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis

  2022cites this paper
• Multiple asters organize the yolk microtubule network during dclk2-GFP zebrafish epiboly

  2022cites this paper
• Microtubule Anchoring: Attaching Dynamic Polymers to Cellular Structures

  2022cites this paper
• CircRNA SOD2 motivates non-small cell lungs cancer advancement with EMT via acting as microRNA-2355-5p’s competing endogenous RNA to mediate calmodulin regulated spectrin associated proteins-2

  2022cites this paper
• Self-assembly of pericentriolar material in interphase cells lacking centrioles

  2022cites this paper
• Mutated in Colorectal Cancer (MCC) is a centrosomal protein that relocalizes to the ncMTOC during intestinal cell differentiation

  2021cites this paper
• Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer

  2021cites this paper
• γ-Tubulin Complexes and Fibrillar Arrays: Two Conserved High Molecular Forms with Many Cellular Functions

  2021cites this paper
• Micron-scale geometrical features of microtubules as regulators of microtubule organization

  2021cites this paper
• From tip to toe - dressing centrioles in γTuRC.

  2021cites this paper
• ENKD1 is a centrosomal and ciliary microtubule-associated protein important for primary cilium assembly and Hedgehog signaling

  2021cites this paper
• Centriole-independent centrosome assembly in interphase mammalian cells

  2021cites this paper
• γ-TuRCs are required for asymmetric microtubule nucleation from the somatic Golgi of Drosophila neurons

  2021cites this paper
• Mechanics of microtubule organizing center clustering and spindle positioning in budding yeast Cryptococcus neoformans.

  2021cites this paper
• Coordination of Zika Virus Infection and Viroplasm Organization by Microtubules and Microtubule-Organizing Centers

  2021cites this paper
• With the Permission of Microtubules: An Updated Overview on Microtubule Function During Axon Pathfinding

  2021cites this paper
• Distinct Microtubule Organizing Center Mechanisms Combine to Generate Neuron Polarity and Arbor Complexity

  2020cites this paper
• Assaying Microtubule Nucleation.

  2020cites this paper
• Loss of CPAP expression promotes sustained EGFR signaling and Epithelial-Mesenchymal Transition in oral cancer cells

  2020cites this paper
• Cep215 is essential for morphological differentiation of astrocytes

  2020cites this paper
• The microtubule organization in the zebrafish yolk adapts to transgene-mediated phenotypic variations

  2020cites this paper
• Spatial Characterization of the Human Centrosome Proteome Opens Up New Horizons for a Small but Versatile Organelle

  2020cites this paper
• Aster repulsion drives local ordering in an active system

  2020cites this paper
• A Proximity Mapping Journey into the Biology of the Mammalian Centrosome/Cilium Complex

  2020cites this paper
• CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression.

  2020cites this paper
• Nucleating microtubules in neurons: Challenges and solutions

  2020cites this paper
• Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability.

  2020cites this paper
• Assembly of the asymmetric human γ-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase

  2020cites this paper
• Binding of alpha‐fodrin to gamma‐tubulin accounts for its role in the inhibition of microtubule nucleation

  2019cites this paper
• Centriolar satellites are required for efficient ciliogenesis and ciliary content regulation

  2019cites this paper
• Primary Cilium in Cancer Hallmarks

  2019cites this paper
• Exploring the molecular interface between hypoxia-inducible factor signalling and mitochondria

  2019cites this paper
• Growth cone-localized microtubule organizing center establishes microtubule orientation in dendrites

  2019cites this paper
• Single‐cell high‐content imaging parameters predict functional phenotype of cultured human bone marrow stromal stem cells

  2019cites this paper
• CG-NAP/Kinase Interactions Fine-Tune T Cell Functions

  2019cites this paper
• The role of GCP8 in microtubule nucleation and cell cicle progression

  2019cites this paper
• Architecture of the Mto1/2 microtubule nucleation complex

  2019cites this paper
• How Does SUMO Participate in Spindle Organization?

  2019cites this paper
• Mechanisms of MTOC clustering and spindle positioning in the budding yeast Cryptococcus neoformans: a microtubule grow-and-catch model

  2019cites this paper
• Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1

  2019cites this paper
• MTOC clustering and nuclear division through proper spindle positioning in yeast: a microtubule grow-and-catch model

  2019cites this paper
• Animal Female Meiosis: The Challenges of Eliminating Centrosomes

  2018cites this paper
• Cognitive Canvas: Molecular Embroidery, Fabric and the Base

  2018cites this paper
• Differential requirement for centriolar satellites in cilium formation among different vertebrate cells

  2018cites this paper
• Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics

  2018cites this paper
• Suppressor Analysis Uncovers That MAPs and Microtubule Dynamics Balance with the Cut7/Kinesin-5 Motor for Mitotic Spindle Assembly in Schizosaccharomyces pombe

  2018cites this paper
• PLK4 is a microtubule-associated protein that self-assembles promoting de novo MTOC formation

  2018cites this paper
• Coming into Focus: Mechanisms of Microtubule Minus-End Organization.

  2018cites this paper
• Tissue-specific degradation of essential centrosome components reveals distinct microtubule populations at microtubule organizing centers

  2018cites this paper
• Cell polarity: having and making sense of direction—on the evolutionary significance of the primary cilium/centrosome organ in Metazoa

  2018cites this paper
• Impact of Centrosome Aberrations on Chromosome Segregation and Tissue Architecture in Cancer.

  2017cites this paper