TRPs and pain

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Seminars in Immunopathology

• Publication date

  2016-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00281-015-0526-0PMID 26374740
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Topical capsaicin (high concentration) for chronic neuropathic pain in adults.

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• The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain.

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• Involvement of TRPM2 in a wide range of inflammatory and neuropathic pain mouse models.

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• Changes in transient receptor potential channels in the rat geniculate ganglion after chorda tympani nerve injury

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• Peripherally increased artemin is a key regulator of TRPA1/V1 expression in primary afferent neurons

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• Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice

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• Enhanced function of TRPV1 via up‐regulation by insulin‐like growth factor‐1 in a rat model of bone cancer pain

  2014cited by this paper
• TRPs and pain.

  2014cited by this paper
• Piezo channels: from structure to function

  2014cited by this paper
• Transient receptor potential (TRP) channels: a clinical perspective

  2014cited by this paper
• Transient receptor potential ankyrin 1 in spinal cord dorsal horn is involved in neuropathic pain in nerve root constriction rats

  2014cited by this paper
• The Effect of Intrathecal Administration TRPA1 Antagonists in a Rat Model of Neuropathic Pain

  2014cited by this paper
• The Cellular Code for Mammalian Thermosensation

  2013cited by this paper
• Targeting TRP channels for pain relief.

  2013cited by this paper
• Dissociated modulation of conditioned place-preference and mechanical hypersensitivity by a TRPA1 channel antagonist in peripheral neuropathy.

  2013cited by this paper
• Disrupting Sensitization of Transient Receptor Potential Vanilloid Subtype 1 Inhibits Inflammatory Hyperalgesia

  2013cited by this paper
• Involvement of TRPM2 in Peripheral Nerve Injury-Induced Infiltration of Peripheral Immune Cells into the Spinal Cord in Mouse Neuropathic Pain Model

  2013cited by this paper
• Topical capsaicin (low concentration) for chronic neuropathic pain in adults

  2013cited by this paper
• Effect of paclitaxel on transient receptor potential vanilloid 1 in rat dorsal root ganglion

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• Novel therapeutic strategy to prevent chemotherapy-induced persistent sensory neuropathy by TRPA1 blockade.

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• Camphor modulates TRPV3 cation channels activity by interacting with critical pore-region cysteine residues.

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  2012cited by this paper
• Topical capsaicin (low concentration) for chronic neuropathic pain in adults.

  2012cited by this paper
• Cyclin-Dependent Kinase 5 Controls TRPV1 Membrane Trafficking and the Heat Sensitivity of Nociceptors through KIF13B

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• TRPM2 Contributes to Inflammatory and Neuropathic Pain through the Aggravation of Pronociceptive Inflammatory Responses in Mice

  2012cited by this paper
• Apigenin, a plant‐derived flavone, activates transient receptor potential vanilloid 4 cation channel

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• TRPV1 antagonists: clinical setbacks and prospects for future development.

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• Peripheral sensitization caused by insulin-like growth factor 1 contributes to pain hypersensitivity after tissue injury

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• Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice

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• Targeting TRPV1 for pain relief: limits, losers and laurels

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• A Comprehensive Review of the Carcinogenic and Anticarcinogenic Potential of Capsaicin

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• TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism

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• TRP Vanilloid 2 Knock-Out Mice Are Susceptible to Perinatal Lethality But Display Normal Thermal and Mechanical Nociception

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• Resolvin D2 Is a Potent Endogenous Inhibitor for Transient Receptor Potential Subtype V1/A1, Inflammatory Pain, and Spinal Cord Synaptic Plasticity in Mice: Distinct Roles of Resolvin D1, D2, and E1

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• Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation

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• Role of TRP channels in pain sensation.

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• PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells.

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• Peripheral sensitization caused by insulin‐like growth factor 1 contributes to pain hypersensitivity after tissue injury

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• Transient receptor potential channels as therapeutic targets

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• Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT‐102 in a randomized healthy volunteer trial

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• Histamine potentiates acid-induced responses mediating transient receptor potential V1 in mouse primary sensory neurons.

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• TRPA1 Mediates Mechanical Currents in the Plasma Membrane of Mouse Sensory Neurons

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• A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain.

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• Attenuation of Mechanical Hypersensitivity by an Antagonist of the TRPA1 Ion Channel in Diabetic Animals

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• Nociceptive signals induce trafficking of TRPA1 to the plasma membrane.

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• Nitrooleic Acid, an Endogenous Product of Nitrative Stress, Activates Nociceptive Sensory Nerves via the Direct Activation of TRPA1

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• TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP

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• TRPV1 and TRPA1 Mediate Peripheral Nitric Oxide-Induced Nociception in Mice

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• Nicotine activates the chemosensory cation channel TRPA1

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• TRPA1 acts as a cold sensor in vitro and in vivo

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• Monoterpenoids induce agonist-specific desensitization of transient receptor potential vanilloid-3 (TRPV3) ion channels.

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• TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons

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• Differential contribution of SNARE‐dependent exocytosis to inflammatory potentiation of TRPV1 in nociceptors

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• Selective Targeting of TRPV1 Expressing Sensory Nerve Terminals in the Spinal Cord for Long Lasting Analgesia

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• Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors

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• The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli.

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• Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress

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• Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1

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• The Nociceptor Ion Channel TRPA1 Is Potentiated and Inactivated by Permeating Calcium Ions*

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• Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain

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• Overexpressed Transient Receptor Potential Vanilloid 3 Ion Channels in Skin Keratinocytes Modulate Pain Sensitivity via Prostaglandin E2

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• Inhibition of transient receptor potential A1 channel by phosphatidylinositol-4,5-bisphosphate.

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• Cold sensitivity of recombinant TRPA1 channels.

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• 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

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• Caenorhabditis elegans TRPA-1 functions in mechanosensation

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• TRPA1 mediates formalin-induced pain

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• Potentiation of glutamatergic synaptic transmission by protein kinase C‐mediated sensitization of TRPV1 at the first sensory synapse

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• The effects of the TRPV1 antagonist SB‐705498 on TRPV1 receptor‐mediated activity and inflammatory hyperalgesia in humans

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• Activin Acutely Sensitizes Dorsal Root Ganglion Neurons and Induces Hyperalgesia via PKC-Mediated Potentiation of Transient Receptor Potential Vanilloid I

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