Cocaine and kindling alter the sensitivity of group II and III metabotropic glutamate receptors in the central amygdala.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of Neurophysiology

• Publication date

  2000-08-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1152/JN.2000.84.2.759PMID 10938303
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Computational model of the role of sensory disorganization in focal task-specific dystonia.

  2000cited by this paper
• Epileptogenesis up-regulates metabotropic glutamate receptor activation of sodium-calcium exchange current in the amygdala.

  2000cited by this paper
• Up‐regulation of the metabotropic glutamate receptor mGluR4 in hippocampal neurons with reduced seizure vulnerability

  2000cited by this paper
• Neuroadaptations in Ionotropic and Metabotropic Glutamate Receptor mRNA Produced by Cocaine Treatment

  1999cited by this paper
• Decreased sensitivity to Group III mGluR agonists in the lateral perforant path following kindling.

  1999cited by this paper
• Pharmacological agents acting at subtypes of metabotropic glutamate receptors.

  1999influential reference
• Metabotropic glutamate receptors: electrophysiological properties and role in plasticity.

  1999cited by this paper
• Effects of varying the expression level of recombinant human mGlu1α receptors on the pharmacological properties of agonists and antagonists

  1999cited by this paper
• Anxiolytic and side-effect profile of LY354740: a potent, highly selective, orally active agonist for group II metabotropic glutamate receptors.

  1998cited by this paper
• Substance dependence as a compulsive behavior

  1998cited by this paper
• Long-Lasting Changes in the Pharmacology and Electrophysiology of Amino Acid Receptors in Amygdala Kindled Neurons

  1998cited by this paper
• Cocaine Administered in Vitro to Brain Slices from Rats Treated with Cocaine Chronically in Vivo Results in a g-Aminobutyric Acid Receptor-Mediated Hyperpolarization Recorded from the Dorsolateral Septum 1

  1998influential reference
• Protein Kinase C and A3 Adenosine Receptor Activation Inhibit Presynaptic Metabotropic Glutamate Receptor (mGluR) Function and Uncouple mGluRs from GTP-Binding Proteins

  1998cited by this paper
• Cocaine administered in vitro to brain slices from rats treated with cocaine chronically in vivo results in a gamma-aminobutyric acid receptor-mediated hyperpolarization recorded from the dorsolateral septum.

  1998cited by this paper
• Whole-Cell Plasticity in Cocaine Withdrawal: Reduced Sodium Currents in Nucleus Accumbens Neurons

  1998cited by this paper
• Protein Kinase C and A 3 Adenosine Receptor Activation Inhibit Presynaptic Metabotropic Glutamate Receptor ( mGluR ) Function and Uncouple mGluRs from GTP-Binding Proteins

  1998cited by this paper
• Decreased Presynaptic Sensitivity to Adenosine after Cocaine Withdrawal

  1998cited by this paper
• Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells.

  1998cited by this paper
• Attenuation of precipitated morphine withdrawal symptoms by acute i.c.v. administration of a group II mGluR agonist

  1997cited by this paper
• Effect of thromboxane A2 antagonists on bronchial hyperresponsiveness induced immediately after interleukin‐8 inhalation in guinea‐pigs

  1997cited by this paper
• rGβ1: A Psychostimulant-Regulated Gene Essential for Establishing Cocaine Sensitization

  1997cited by this paper
• Attenuation of morphine withdrawal symptoms by subtype‐selective metabotropic glutamate receptor antagonists

  1997cited by this paper
• Chronic Cocaine Enhances γ-Aminobutyric Acid and Glutamate Release by Altering Presynaptic and not Postsynaptic γ-Aminobutyric AcidB Receptors within the Rat Dorsolateral Septal Nucleus

  1997influential reference
• Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile.

  1997cited by this paper
• LY354740 is a potent and highly selective group II metabotropic glutamate receptor agonist in cells expressing human glutamate receptors.

  1997cited by this paper
• Epileptogenesis In Vivo Enhances the Sensitivity of Inhibitory Presynaptic Metabotropic Glutamate Receptors in Basolateral Amygdala Neurons In Vitro

  1997cited by this paper
• Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): a potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties.

  1997cited by this paper
• Loss of long-lasting potentiation mediated by group III mGluRs in amygdala neurons in kindling-induced epileptogenesis.

  1997cited by this paper
• Pharmacology and functions of metabotropic glutamate receptors.

  1997cited by this paper
• Cocaine Dependence

  1997cited by this paper
• Chronic cocaine enhances gamma-aminobutyric acid and glutamate release by altering presynaptic and not postsynaptic gamma-aminobutyric acidB receptors within the rat dorsolateral septal nucleus.

  1997cited by this paper
• Design, Synthesis, and Pharmacological Characterization of (+)-2- Aminobicyclo(3.1.0)hexane-2,6-dicarboxylic Acid (LY354740): A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties.

  1997cited by this paper
• Modulation of mEPSCs in olfactory bulb mitral cells by metabotropic glutamate receptors.

  1997cited by this paper
• Synaptic transmission and plasticity in the amygdala

  1996cited by this paper
• Modification of serotonin responses in rat dorsolateral septal nucleus neurons by acute and chronic cocaine.

  1996cited by this paper
• Drug addiction: the yin and yang of hedonic homeostasis.

  1996cited by this paper
• Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization

  1996cited by this paper
• A common mechanism mediates long-term changes in synaptic transmission after chronic cocaine and morphine.

  1996influential reference
• Metabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons

  1996cited by this paper
• Effects of excitotoxic lesions of the central amygdaloid nucleus on the potentiation of reward-related stimuli by intra-accumbens amphetamine.

  1996cited by this paper
• Activation of metabotropic glutamate receptors induce differential effects on synaptic transmission in the dentate gyrus and CA1 of the hippocampus in the anaesthetized rat.

  1996cited by this paper
• Loss of mGluR-mediated hyperpolarizations and increase in mGluR depolarizations in basolateral amygdala neurons in kindling-induced epilepsy.

  1996cited by this paper
• Latest eruptions in metabotropic glutamate receptors.

  1996cited by this paper
• Pharmacology of metabotropic glutamate receptors at the mossy fiber synapses of the guinea pig hippocampus.

  1995cited by this paper
• Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3.

  1995cited by this paper
• Amygdala and extended amygdala

  1995cited by this paper
• Roles of specific metabotropic glutamate receptor subtypes in regulation of hippocampal CA1 pyramidal cell excitability.

  1995cited by this paper
• Effects of the dopamine D-1 antagonist SCH 23390 microinjected into the accumbens, amygdala or striatum on cocaine self-administration in the rat.

  1995cited by this paper
• Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1

  1995cited by this paper
• Metabotropic glutamate receptor modulation of synaptic transmission in corticostriatal co-cultures: role of calcium influx.

  1995cited by this paper
• Metabotropic glutamate receptors: novel targets for drug development.

  1995cited by this paper
• Sensitization of cocaine-stimulated increase in extracellular levels of corticotropin-releasing factor from the rat amygdala after repeated administration as determined by intracranial microdialysis.

  1995cited by this paper
• The metabotropic glutamate receptors: structure and functions.

  1995cited by this paper
• Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine.

  1994cited by this paper
• The amygdala complex: multiple roles in associative learning and attention.

  1994cited by this paper
• Corticotropin releasing factor neurons are innervated by calcitonin gene-related peptide terminals in the rat central amygdaloid nucleus.

  1994cited by this paper
• Dopaminergic antagonism within the nucleus accumbens or the amygdala produces differential effects on intravenous cocaine self-administration under fixed and progressive ratio schedules of reinforcement.

  1993cited by this paper
• The organization of the efferent projections from the pontine parabrachial area to the amygdaloid complex: A phaseolus vulgaris leucoagglutinin (PHA‐L) study in the rat

  1993cited by this paper
• Drug addiction: a model for the molecular basis of neural plasticity.

  1993cited by this paper
• Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine.

  1993cited by this paper
• Protein kinase C modulates glutamate receptor inhibition of Ca2+ channels and synaptic transmission

  1993cited by this paper
• Kindling-induced long-lasting changes in synaptic transmission in the basolateral amygdala.

  1992cited by this paper
• Epileptogenesis reduces the sensitivity of presynaptic gamma-aminobutyric acidB receptors on glutamatergic afferents in the amygdala.

  1992cited by this paper
• Metabotropic glutamate receptors are required for the induction of long-term potentiation.

  1992cited by this paper
• Metabotropic Glutamate Receptors: Electrophysiological Properties and Role in Plasticity

  1992cited by this paper
• Effect of chronic cocaine treatment on D2 receptors regulating the release of dopamine and acetylcholine in the nucleus accumbens and striatum.

  1992cited by this paper
• The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction.

  1992influential reference
• Sensitization of locus ceruleus neurons during withdrawal from chronic stimulants and antidepressants.

  1992cited by this paper
• Trans-ACPD and L-APB presynaptically inhibit excitatory glutamatergic transmission in the basolateral amygdala (BLA).

  1992cited by this paper
• Postcocaine anhedonia. An animal model of cocaine withdrawal.

  1991cited by this paper
• Possible role for G-proteins in behavioral sensitization to cocaine.

  1991cited by this paper
• A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function.

  1991cited by this paper
• Cocaine addiction: psychology and neurophysiology.

  1991cited by this paper
• Chronic Cocaine Treatment Decreases Levels of the G Protein Subunits Giα and Goα in Discrete Regions of Rat Brain

  1990cited by this paper
• Chronic cocaine treatment decreases levels of the G protein subunits Gi alpha and Go alpha in discrete regions of rat brain.

  1990cited by this paper
• Cocaine dependence.

  1989cited by this paper
• Regulation of G proteins by chronic morphine in the rat locus coeruleus.

  1989cited by this paper
• Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex.

  1989influential reference
• The role of context and conditioning in behavioral sensitization to cocaine.

  1987cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983cited by this paper
• Modification of seizure activity by electrical stimulation. II. Motor seizure.

  1972cited by this paper
• A permanent change in brain function resulting from daily electrical stimulation.

  1969cited by this paper

• A review on the role of metabotropic glutamate receptors in neuroplasticity following psychostimulant use disorder.

  2023cites this paper
• Cocaine use disorder: A look at metabotropic glutamate receptors and glutamate transporters.

  2020cites this paper
• Amygdala: Neuroanatomical and Morphophysiological Features in Terms of Neurological and Neurodegenerative Diseases

  2020cites this paper
• Panic results in unique molecular and network changes in the amygdala that facilitate fear responses.

  2018cites this paper
• 1 Metabotropic Receptors for Glutamate and GABA

  2017cites this paper
• Neuroadaptive changes in metabotropic glutamate mGlu2/3R expression during different phases of cocaine addiction in rats

  2017cites this paper
• Presynaptic G Protein-Coupled Receptors: Gatekeepers of Addiction?

  2016influential citation
• Metabotropic Glutamate Receptors in Central Nervous System Diseases.

  2016cites this paper
• Discovery of (1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371·HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepressant-Like Activity.

  2016cites this paper
• Dexmedetomidine Dose-Dependently Attenuates Ropivacaine-Induced Seizures and Negative Emotions Via Inhibiting Phosphorylation of Amygdala Extracellular Signal-Regulated Kinase in Mice

  2015cites this paper
• Evaluación de la eficacia de medicamentos empleados en el tratamiento de la dependencia de cocaína: Revisión sistemática y metaanálisis de los fármacos antiepilépticos y antipsicóticos

  2015cites this paper
• Nociception in Primate STT Cells Differentially Modulate Brief and Prolonged Groups II and III Metabotropic Glutamate Receptors

  2015cites this paper
• Novel metabotropic glutamate receptor 4 and glutamate receptor 8 therapeutics for the treatment of anxiety

  2015cites this paper
• Amygdala pain mechanisms.

  2015cites this paper
• Dopamine transporter (DAT), nicotinic acetylcholine receptor (nAChR), and metabotropic glutamate receptor 2 (mGlu2) irreversible probes for identifying anti-psychostimulant therapeutics

  2014cites this paper
• Recent approaches for studying the role of glia.

  2014cites this paper
• Metabotropic Glutamate Receptor 3 Is Associated with Heroin Dependence but Not Depression or Schizophrenia in a Chinese Population

  2014cites this paper
• Group III Metabotropic Glutamate Receptors: Pharmacology, Physiology and Therapeutic Potential

  2014cites this paper
• Electroacupuncture Reduces Cocaine-Induced Seizures and Mortality in Mice

  2013cites this paper
• Olfactory Hallucinations without Clinical Motor Activity: A Comparison of Unirhinal with Birhinal Phantosmia

  2013cites this paper
• Traitement d'une douleur neuropathique par la modulation pharmacologique du complexe basolatéral de l'amygdale

  2013cites this paper
• Group III metabotropic glutamate receptors and drug addiction

  2013cites this paper
• Metabotropic Receptors for Glutamate and GABA

  2012cites this paper
• Metabotropic Glutamate 2/3 Receptor Agonists and Positive Allosteric Modulators of Metabotropic Glutamate Receptor 2 as Novel Agents for the Treatment of Schizophrenia

  2012cites this paper
• Modulation of synaptic transmission from primary afferents to spinal substantia gelatinosa neurons by group III mGluRs in GAD65-EGFP transgenic mice.

  2011cites this paper
• Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: factor in the transition to dependence.

  2010cites this paper
• Cognitive Impairment in Pain through Amygdala-Driven Prefrontal Cortical Deactivation

  2010cites this paper
• Allosteric Metabotropic Glutamate Receptor 7 Antagonists In Vitro Pharmacological Characterization of Novel Isoxazolopyridone Derivatives as

  2010cites this paper
• Behavioral and functional evidence of mGlu2/3 and mGlu5 metabotropic glutamate receptor dysregulation in cocaine-escalated rats: Factor in the transition to dependence

  2010cites this paper
• Group II metabotropic glutamate receptors (mGlu2/3) in drug addiction.

  2010cites this paper
• 2-Methyl-6-phenylethynyl-pyridine (MPEP), a non-competitive mGluR5 antagonist, differentially affects the anticonvulsant activity of four conventional antiepileptic drugs against amygdala-kindled seizures in rats

  2009cites this paper
• Chronic Toxicity of Cocaine use

  2009cites this paper
• Activity‐dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain

  2008cites this paper
• Glutamatergic substrates of drug addiction and alcoholism.

  2008cites this paper
• Group III Metabotropic Glutamate Receptors (mGlu4, mGlu6, mGlu7, and mGlu8)

  2008cites this paper
• Metabotropic Glutamate 2/3 Receptors in the Ventral Tegmental Area and the Nucleus Accumbens Shell Are Involved in Behaviors Relating to Nicotine Dependence

  2007influential citation
• Involvement of group II metabotropic glutamate receptors in stress-induced behavioural sensitization

  2007cites this paper
• Metabotropic glutamate receptors

  2007cites this paper
• Metabotropic glutamate receptor mediated synaptic plasticity in the bed nucleus of the stria terminalis as a target for stress, anxiety and addiction disorders.

  2006cites this paper
• Anxiolytic-like effects of group III mGlu receptor ligands in the hippocampus involve GABAA signaling.

  2006cites this paper
• LTP in the lateral amygdala during cocaine withdrawal

  2006cites this paper
• Enhanced group II mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala

  2006cites this paper
• Melancholia: The Diagnosis, Pathophysiology and Treatment of Depressive Illness

  2006cites this paper
• Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain.

  2006cites this paper
• Effects of mGlu2 or mGlu3 receptor deletions on mGlu2/3 receptor agonist (LY354740)-induced brain c-Fos expression: specific roles for mGlu2 in the amygdala and subcortical nuclei, and mGlu3 in the hippocampus.

  2006cites this paper
• Role of peripheral group I and II metabotropic glutamate receptors in IL‐1β‐induced mechanical allodynia in the orofacial area of conscious rats

  2005cites this paper
• Chronic Cocaine Administration Switches Corticotropin-Releasing Factor2 Receptor-Mediated Depression to Facilitation of Glutamatergic Transmission in the Lateral Septum

  2005cites this paper
• Protein kinase A‐dependent enhanced NMDA receptor function in pain‐related synaptic plasticity in rat amygdala neurones

  2005cites this paper
• Amygdala Metabotropic Glutamate Receptors and Kindling

  2005cites this paper
• Group II and III Metabotropic Glutamate Receptors Suppress Excitatory Synaptic Transmission in the Dorsolateral Bed Nucleus of the Stria Terminalis

  2005cites this paper
• Anxiolytic effects of kindling role of anatomical location of the kindling electrode in response to kindling of the right basolateral amygdala.

  2004cites this paper
• The ups and downs of addiction: role of metabotropic glutamate receptors.

  2004cites this paper
• Differential roles of mGluR1 and mGluR5 in brief and prolonged nociceptive processing in central amygdala neurons.

  2004cites this paper
• Medial perforant path inhibition mediated by mGluR7 is reduced after status epilepticus.

  2004cites this paper
• The Amygdala and Persistent Pain

  2004cites this paper
• Anxiolytic Activity of the MGLU2/3 Receptor Agonist LY354740 on the Elevated Plus Maze is Associated with the Suppression of Stress-Induced c-Fos in the Hippocampus and Increases in c-Fos Induction in Several Other Stress-Sensitive Brain Regions

  2004cites this paper
• Cognitive Corticotropin-Releasing Factor and Urocortin I Modulate Excitatory Glutamatergic Synaptic Transmission

  2004cites this paper
• Enhanced group III mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala.

  2004cites this paper
• LY354740, an mGlu2/3 Receptor Agonist as a Novel Approach to Treat Anxiety/Stress

  2003cites this paper
• Antidepressant and anxiolytic‐like effects in mice lacking the group III metabotropic glutamate receptor mGluR7

  2003cites this paper
• LY-354740 (Eli Lilly).

  2003cites this paper
• Differential sensitization of amygdala neurons to afferent inputs in a model of arthritic pain.

  2003cites this paper
• Insight into the function of Group I and Group II metabotropic glutamate (mGlu) receptors: behavioural characterization and implications for the treatment of CNS disorders

  2003cites this paper
• The amygdaloid complex: anatomy and physiology.

  2003cites this paper
• Synaptic Plasticity in the Amygdala in a Model of Arthritic Pain: Differential Roles of Metabotropic Glutamate Receptors 1 and 5

  2003influential citation
• Glutamate metabotropic receptors as targets for drug therapy in epilepsy.

  2003cites this paper
• Neuroprotective activity of metabotropic glutamate receptor ligands.

  2002cites this paper
• NAALADase (GCP II) inhibition prevents cocaine-kindled seizures.

  2002cites this paper
• Molecular and Cellular Biology of Neuroprotection in the CNS

  2002cites this paper
• Modulation of Group II Metabotropic Glutamate Receptor Signaling by Chronic Cocaine

  2002cites this paper
• Pharmacology of Glutamate Receptors

  2002cites this paper
• Group II metabotropic glutamate receptors within the amygdala regulate fear as assessed with potentiated startle in rats.

  2002cites this paper
• Calcineurin Plays Different Roles in Group II Metabotropic Glutamate Receptor- and NMDA Receptor-Dependent Long-Term Depression

  2002cites this paper
• Brain-derived neurotrophic factor expression is increased in the rat amygdala, piriform cortex and hypothalamus following repeated amphetamine administration.

  2002cites this paper
• The anxiolytic action of mGlu2/3 receptor agonist, LY354740, in the fear-potentiated startle model in rats is mechanistically distinct from diazepam.

  2002cites this paper
• Metabotropic glutamate receptors: novel targets for pain relief

  2001cites this paper
• Increased Seizure Susceptibility in Mice Lacking Metabotropic Glutamate Receptor 7

  2001cites this paper
• Neurochemical and pharmacological aspects of cocaine-induced seizures.

  2001cites this paper
• Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells.

  2000cites this paper