Differential roles of mGluR1 and mGluR5 in brief and prolonged nociceptive processing in central amygdala neurons.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Neurophysiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1152/JN.00485.2003PMID 13679408
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Emotion circuits in the brain.

  2009influential reference
• Using chronic pain to predict depressive morbidity in the general population.

  2003cited by this paper
• The human amygdala and the emotional evaluation of sensory stimuli.

  2003cited by this paper
• Distinct Functional Roles of the Metabotropic Glutamate Receptors 1 and 5 in the Rat Globus Pallidus

  2003cited by this paper
• Differential sensitization of amygdala neurons to afferent inputs in a model of arthritic pain.

  2003influential reference
• Synaptic Plasticity in the Amygdala in a Model of Arthritic Pain: Differential Roles of Metabotropic Glutamate Receptors 1 and 5

  2003influential reference
• Metabotropic glutamate receptor involvement in models of acute and persistent pain: prospects for the development of novel analgesics.

  2002cited by this paper
• Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex.

  2002cited by this paper
• Long‐term changes in behavior and regional cerebral blood flow associated with painful peripheral mononeuropathy in the rat

  2002cited by this paper
• Central processing of rectal pain in patients with irritable bowel syndrome: an fMRI study

  2002cited by this paper
• Peripheral metabotropic glutamate receptors as drug targets for pain relief

  2002cited by this paper
• Processing of nociceptive mechanical and thermal information in central amygdala neurons with knee-joint input.

  2002influential reference
• Metabotropic glutamate receptors – important modulators of nociception and pain behavior

  2002influential reference
• Painful stimuli evoke different stimulus-response functions in the amygdala, prefrontal, insula and somatosensory cortex: a single-trial fMRI study.

  2002cited by this paper
• Treatment of allergic rhinitis: H1-antihistamines and intranasal steroids.

  2002cited by this paper
• Microinjection of morphine into various amygdaloid nuclei differentially affects nociceptive responsiveness and RVM neuronal activity

  2002cited by this paper
• Pain Pathways and Parabrachial Circuits in the Rat

  2002cited by this paper
• Subcortical structures involved in pain processing: evidence from single‐trial fMRI

  2002cited by this paper
• Anxiety and affective style: role of prefrontal cortex and amygdala.

  2002cited by this paper
• Allosteric modulators of group I metabotropic glutamate receptors: novel subtype-selective ligands and therapeutic perspectives.

  2002cited by this paper
• Glutamate Receptors and Nociception

  2001cited by this paper
• Metabotropic Glutamate Receptor Subtypes 1 and 5 Are Activators of Extracellular Signal-Regulated Kinase Signaling Required for Inflammatory Pain in Mice

  2001cited by this paper
• Metabotropic Glutamate Receptors 1 and 5 Differentially Regulate CA1 Pyramidal Cell Function

  2001cited by this paper
• Projections from the nociceptive area of the central nucleus of the amygdala to the forebrain: a PHA‐L study in the rat

  2001cited by this paper
• Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders.

  2001cited by this paper
• Molecular determinants of metabotropic glutamate receptor signaling.

  2001cited by this paper
• Alternative diagnostic criteria for major depressive disorder in patients with chronic pain

  2001cited by this paper
• Subjective Ratings of Pain Correlate with Subcortical-Limbic Blood Flow: An fMRI Study

  2001cited by this paper
• A novel method for convenient assessment of arthritic pain in voluntarily walking rats.

  2001cited by this paper
• Contextual and auditory fear conditioning are mediated by the lateral, basal, and central amygdaloid nuclei in rats.

  2001cited by this paper
• Comparison of paired‐pulse facilitation of AMPA and NMDA synaptic currents in the lateral amygdala

  2001cited by this paper
• Pain and Emotion: Effects of Affective Picture Modulation

  2001cited by this paper
• Synaptic plasticity in the lateral amygdala: a cellular hypothesis of fear conditioning.

  2001cited by this paper
• Memory systems in the brain.

  2000cited by this paper
• Epileptogenesis up-regulates metabotropic glutamate receptor activation of sodium-calcium exchange current in the amygdala.

  2000cited by this paper
• Activation of Group II Metabotropic Glutamate Receptors Induces Long-Term Depression of Synaptic Transmission in the Rat Amygdala

  2000cited by this paper
• Cocaine and kindling alter the sensitivity of group II and III metabotropic glutamate receptors in the central amygdala.

  2000cited by this paper
• Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells.

  2000cited by this paper
• Pain modulation: expectation, opioid analgesia and virtual pain.

  2000cited by this paper
• Regulation of Neurotransmitter Release by Metabotropic Glutamate Receptors

  2000cited by this paper
• Differential innervation of parvalbumin‐immunoreactive interneurons of the basolateral amygdaloid complex by cortical and intrinsic inputs

  2000cited by this paper
• Functional activities of the amygdala: an overview.

  2000cited by this paper
• The Amygdala : a functional analysis

  2000cited by this paper
• Fear and anxiety: divergent effects on human pain thresholds

  2000cited by this paper
• Role of metabotropic glutamate receptor subtype mGluR1 in brief nociception and central sensitization of primate STT cells.

  1999influential reference
• Regional brain function, emotion and disorders of emotion.

  1999cited by this paper
• An Inhibitory Interface Gates Impulse Traffic between the Input and Output Stations of the Amygdala

  1999cited by this paper
• Organization of projections to the lateral amygdala from auditory and visual areas of the thalamus in the rat

  1999cited by this paper
• Pain Pathways Involved in Fear Conditioning Measured with Fear-Potentiated Startle: Lesion Studies

  1999cited by this paper
• Why We Think Plasticity Underlying Viewpoint Pavlovian Fear Conditioning Occurs in the Basolateral Amygdala

  1999cited by this paper
• Neuroprotective Actions of Novel and Potent Ligands of Group I and Group II Metabotropic Glutamate Receptors

  1999cited by this paper
• Metabotropic glutamate receptors: electrophysiological properties and role in plasticity.

  1999cited by this paper
• Negative affect and pain in arthritis.

  1999cited by this paper
• Group I metabotropic glutamate receptors: implications for brain diseases.

  1999cited by this paper
• Direct synaptic connections of axons from superior colliculus with identified thalamo‐amygdaloid projection neurons in the rat: Possible substrates of a subcortical visual pathway to the amygdala

  1999cited by this paper
• A neurobiological perspective on emotionally influenced, long-term memory.

  1999cited by this paper
• Human brain activation under controlled thermal stimulation and habituation to noxious heat: An fMRI study

  1999cited by this paper
• Associative Processes in Addiction and Reward The Role of Amygdala‐Ventral Striatal Subsystems

  1999cited by this paper
• Pharmacological agents acting at subtypes of metabotropic glutamate receptors.

  1999cited by this paper
• Functions of the Amygdala and Related Forebrain Areas in Attention and Cognition

  1999cited by this paper
• Parallel circuits for emotional coping behaviour: New pieces in the puzzle

  1998cited by this paper
• A Lateralized Deficit in Morphine Antinociception after Unilateral Inactivation of the Central Amygdala

  1998cited by this paper
• Anatomic and physiologic substrates of emotion in an animal model.

  1998cited by this paper
• Neural plasticity and emotional memory

  1998cited by this paper
• Epileptogenesis In Vivo Enhances the Sensitivity of Inhibitory Presynaptic Metabotropic Glutamate Receptors in Basolateral Amygdala Neurons In Vitro

  1997cited by this paper
• Pain processing during three levels of noxious stimulation produces differential patterns of central activity

  1997cited by this paper
• Transneuronal Labeling of a Nociceptive Pathway, the Spino-(Trigemino-)Parabrachio-Amygdaloid, in the Rat

  1997cited by this paper
• Pharmacology and functions of metabotropic glutamate receptors.

  1997cited by this paper
• Organization of intra-amygdaloid circuitries in the rat: an emerging framework for understanding functions of the amygdala.

  1997cited by this paper
• Organization of Glutamate Receptors at the Synapse

  1997cited by this paper
• Differential plasma membrane distribution of metabotropic glutamate receptors mGluR1 alpha, mGluR2 and mGluR5, relative to neurotransmitter release sites.

  1997cited by this paper
• Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?

  1996cited by this paper
• Neural systems for the expression of hypoalgesia during nonassociative fear.

  1996cited by this paper
• Involvement of the spino-parabrachio -amygdaloid and -hypothalamic pathways in the autonomic and affective emotional aspects of pain.

  1996cited by this paper
• Amygdaloid CRF Pathways: Role in Autonomic, Neuroendocrine, and Behavioral Responses to Stress

  1993cited by this paper
• N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint.

  1993influential reference
• Metabotropic Glutamate Receptors: Electrophysiological Properties and Role in Plasticity

  1992cited by this paper
• The amygdala is essential for the expression of conditional hypoalgesia.

  1992cited by this paper
• Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear

  1988cited by this paper
• Neuronal architecture in the rat central nucleus of the amygdala: A cytological, hodological, and immunocytochemical study

  1986cited by this paper
• Electrophysiological characteristics of amygdaloid central nucleus neurons during Pavlovian fear conditioning in the rabbit

  1985cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983influential reference
• An autoradiographic study of the projections of the central nucleus of the monkey amygdala

  1981cited by this paper
• Amygdaloid projections to subcortical structures within the basal forebrain and brainstem in the rat and cat

  1978cited by this paper

• Metabotropic Glutamate Receptor 5: A Potential Target for Neuropathic Pain Treatment

  2024cites this paper
• Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain

  2022cites this paper
• Recent Advances in the Modulation of Pain by the Metabotropic Glutamate Receptors

  2022cites this paper
• A compendium of validated pain genes

  2022cites this paper
• Sphingosine-1-phosphate receptor 1 agonist SEW2871 alters membrane properties of late-firing somatostatin expressing neurons in the central lateral amygdala

  2021cites this paper
• Left and right hemispheric lateralization of the amygdala in pain.

  2020cites this paper
• Mutations in Metabotropic Glutamate Receptor 1 Contribute to Natural Short Sleep Trait.

  2020cites this paper
• Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA–GABA transmission in highly addicted rats

  2020cites this paper
• Amygdala physiology in pain.

  2020cites this paper
• Amygdala group II mGluRs mediate the inhibitory effects of systemic group II mGluR activation on behavior and spinal neurons in a rat model of arthritis pain.

  2019cites this paper
• Emerging Trends in Pain Modulation by Metabotropic Glutamate Receptors

  2019cites this paper
• Neuropharmacological Properties of the Essential Oil of Bergamot for the Clinical Management of Pain-Related BPSDs.

  2019cites this paper
• Parabrachial-to-amygdala control of aversive learning

  2019cites this paper
• Metabotropic Glutamate Receptors and Neurological/Psychiatric Disorders

  2019cites this paper
• Hippocampal-amygdala interactions mediate uncertainty-dependent resistance to extinction following fear conditioning

  2019cites this paper
• Contribution of Corticotropin-Releasing Factor Receptor 1 (CRF1) to Serotonin Receptor 5-HT2CR Function in Amygdala Neurons in a Neuropathic Pain Model

  2019cites this paper
• Characterization of G-protein coupled receptors in pain, depression and anxiety

  2018cites this paper
• The central amygdala to periaqueductal gray pathway comprises intrinsically distinct neurons differentially affected in a model of inflammatory pain

  2018cites this paper
• Corticotropin-Releasing Factor Receptors Modulate Oxytocin Release in the Dorsolateral Bed Nucleus of the Stria Terminalis (BNST) in Male Rats

  2018cites this paper
• Metabotropic Glutamate Receptors in Amygdala Functions

  2017cites this paper
• Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator

  2017cites this paper
• Monomethyl fumarate inhibits pain behaviors and amygdala activity in a rat arthritis model

  2017cites this paper
• Amygdala Plasticity and Pain

  2017cites this paper
• Nociception modulation by supraspinal group III metabotropic glutamate receptors

  2017cites this paper
• The Role of Stress Regulation on Neural Plasticity in Pain Chronification

  2016cites this paper
• Metabotropic glutamate 5 receptor in the infralimbic cortex contributes to descending pain facilitation in healthy and arthritic animals.

  2016cites this paper
• Metabotropic Glutamate Receptors in Central Nervous System Diseases.

  2016cites this paper
• Brain penetration, target engagement, and disposition of the blood‐brain barrier‐crossing bispecific antibody antagonist of metabotropic glutamate receptor type 1

  2016cites this paper
• Pain Modulation By The Amygdala: Hemispheric Lateralization Of Pro- And Anti-nociceptive Properties During The Progression Of Inflammatory Pain

  2015influential citation
• Amygdala pain mechanisms.

  2015influential citation
• Short report Open Access

  2015cites this paper
• Depression-Like Behaviors in the Chronic Neuropathic Pain State Calcium-Permeable AMPA Receptors in the Nucleus Accumbens Regulate

  2015cites this paper
• mGluRs head to toe in pain.

  2015cites this paper
• The lateral parabrachial nucleus is actively involved in the acquisition of fear memory in mice

  2015cites this paper
• Oral administration of the p38&agr; MAPK inhibitor, UR13870, inhibits affective pain behavior after spinal cord injury

  2014cites this paper
• Supraspinal metabotropic glutamate receptors: a target for pain relief and beyond

  2014cites this paper
• CB1 augments mGluR5 function in medial prefrontal cortical neurons to inhibit amygdala hyperactivity in an arthritis pain model

  2014cites this paper
• The mGluR5 Antagonist Fenobam Induces Analgesic Conditioned Place Preference in Mice with Spared Nerve Injury

  2014cites this paper
• Nouveaux mécanismes d'action du récepteur mGlu7a dans le thalamus : de la synapse au comportement

  2014cites this paper
• Neuropeptide S: a novel regulator of pain-related amygdala plasticity and behaviors.

  2013cites this paper
• The amygdala between sensation and affect: a role in pain

  2013cites this paper
• 5-HT2CR blockade in the amygdala conveys analgesic efficacy to SSRIs in a rat model of arthritis pain

  2013cites this paper
• The Endogenous Opioids Related with Antinociceptive Effects Induced by Electrical Stimulation into the Amygdala

  2013influential citation
• The Physiological and Morphological Responses of the Bladder Urothelium to Differential Injury

  2013cites this paper
• Urine Trouble: A Molecular and Anatomical Examination of Bladder Pain

  2013cites this paper
• Modulation of pyramidal cell output in the medial prefrontal cortex by mGluR5 interacting with CB1.

  2013cites this paper
• Neural mechanisms of pain and alcohol dependence.

  2013cites this paper
• Central Amygdala Metabotropic Glutamate Receptor 5 in the Modulation of Visceral Pain

  2012influential citation
• Whiplash-like facet joint loading initiates glutamatergic responses in the DRG and spinal cord associated with behavioral hypersensitivity.

  2012cites this paper
• Allosteric Modulation of Metabotropic Glutamate Receptor 5 as a Treatment for Pain

  2012cites this paper
• Metabotropic glutamate receptor 5 (mGluR5) regulates bladder nociception

  2012cites this paper
• Pain-related changes in the brain: diagnostic and therapeutic potentials.

  2012cites this paper
• Metabotropic glutamate receptors and the control of chronic pain.

  2012cites this paper
• Pain-related deactivation of medial prefrontal cortical neurons involves mGluR1 and GABA(A) receptors.

  2011influential citation
• Metabotropic Glutamate Receptor Subtype 8 in the Amygdala Modulates Thermal Threshold, Neurotransmitter Release, and Rostral Ventromedial Medulla Cell Activity in Inflammatory Pain

  2011cites this paper
• Mitochondrial Reactive Oxygen Species Are Activated by mGluR5 through IP3 and Activate ERK and PKA to Increase Excitability of Amygdala Neurons and Pain Behavior

  2011influential citation
• Metabotropic glutamate receptors as targets for analgesia: antagonism, activation, and allosteric modulation.

  2011cites this paper
• MRI analysis of mGluR5 and mGluR1 antagonists, MTEP and R214127 in the cerebral forebrain of awake, conscious rats.

  2011cites this paper
• Differential effects of mGluR7 and mGluR8 activation on pain-related synaptic activity in the amygdala.

  2011cites this paper
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  2011cites this paper
• mGluR1, but not mGluR5, activates feed-forward inhibition in the medial prefrontal cortex to impair decision making.

  2011cites this paper
• Reactive oxygen species are involved in group I mGluR-mediated facilitation of nociceptive processing in amygdala neurons.

  2010cites this paper
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  2010cites this paper
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  2010cites this paper
• Facilitation of synaptic transmission and pain responses by CGRP in the amygdala of normal rats

  2010cites this paper
• Activation of Metabotropic Glutamate Receptor 5 in the Amygdala Modulates Pain-Like Behavior

  2010influential citation
• Central modulation of pain.

  2010cites this paper
• The Contribution Of Nmda Receptors Within The Central Nucleus Of The Amygdala To The Suppression Of Pain Affect

  2010cites this paper
• Enhanced pronociception by amygdaloid group I metabotropic glutamate receptors in nerve-injured animals.

  2009cites this paper
• Hemispheric lateralization of pain processing by amygdala neurons.

  2009cites this paper
• Forebrain pain mechanisms.

  2009cites this paper
• The use of novel techniques to study the roles of cytokines in joint pain and inflammation

  2008cites this paper
• 4.05 – Pain Sensitization

  2008cites this paper
• PKA and ERK, but not PKC, in the amygdala contribute to pain-related synaptic plasticity and behavior

  2008influential citation
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  2008cites this paper
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  2008cites this paper
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  2008cites this paper
• Pro- and anti-nociceptive effects of corticotropin-releasing factor (CRF) in central amygdala neurons are mediated through different receptors.

  2008cites this paper
• Spinal CGRP1 receptors contribute to supraspinally organized pain behavior and pain‐related sensitization of amygdala neurons

  2007cites this paper
• The role of group I metabotropic glutamate receptors in schizophrenia

  2007cites this paper
• Glutamate receptor ligands.

  2007cites this paper
• Glutamate and metabotropic glutamate receptors associated with innervation of the uterine cervix during pregnancy: Receptor antagonism inhibits c‐fos expression in rat lumbosacral spinal cord at parturition

  2007cites this paper
• Amygdala GABA‐A receptor involvement in mediating sensory‐discriminative and affective‐motivational pain responses in a rat model of peripheral nerve injury

  2007cites this paper
• Differential effects of CRF1 and CRF2 receptor antagonists on pain-related sensitization of neurons in the central nucleus of the amygdala.

  2007influential citation
• Pain-related anxiety-like behavior requires CRF1 receptors in the amygdala

  2007cites this paper
• Functional neuroanatomy of pain.

  2006cites this paper
• Calibrated forceps: a sensitive and reliable tool for pain and analgesia studies.

  2006cites this paper
• Enhanced group II mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala

  2006cites this paper
• Metabotropic glutamate and cannabinoid receptor crosstalk in periaqueductal grey pain processing.

  2006cites this paper
• Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain.

  2006influential citation
• Calibrated forceps: a useful tool to study mechanical nociception.

  2006cites this paper
• Chapter 11 Subcortical processing of nociceptive information: basal ganglia and amygdala.

  2006cites this paper
• Glutamate receptors and pain.

  2006cites this paper
• Nitric oxide synthase-containing neurons in the amygdaloid nuclear complex of the rat

  2006cites this paper
• Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP.

  2006cites this paper
• mGluR1 and mGluR5 antagonists in the amygdala inhibit different components of audible and ultrasonic vocalizations in a model of arthritic pain

  2005influential citation
• Computerized analysis of audible and ultrasonic vocalizations of rats as a standardized measure of pain-related behavior.

  2005cites this paper
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  2005cites this paper