Amiodarone in patients with previous drug-mediated torsade de pointes. Long-term safety and efficacy.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Annals of Internal Medicine

• Publication date

  1989-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.7326/0003-4819-111-7-574PMID 2774388
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Amiodarone blocks inactivated cardiac sodium channels

  2004cited by this paper
• Amiodarone for sustained ventricular tachycardia: efficacy, safety, and factors influencing long-term outcome.

  1987cited by this paper
• Effects of Amiodarone and Desethylamiodarone on Rabbit Myocardial β‐Adrenoceptors and Serum Thyroid Hormones—Absence of Relationship to Serum and Myocardial Drug Concentrations

  1986cited by this paper
• Polymorphous ventricular tachycardia: clinical characterization, therapy, and the QT interval.

  1986cited by this paper
• Action Potential Prolongation and Induction of Abnormal Automaticity by Low Quinidine Concentrations in Canine Purkinje Fibers Relationship to Potassium and Cycle Length

  1985cited by this paper
• Acute effects of amiodarone on the electrophysiologic properties of isolated neonatal and adult cardiac fibers.

  1985cited by this paper
• Idiopathic long QT syndrome: progress and questions.

  1985cited by this paper
• Long QT: good, bad or indifferent?

  1984cited by this paper
• Ventricular tachyarrhythmias in the long QT syndromes.

  1984cited by this paper
• The Electrophysiology and Pharmacology of Verapamil, Flecainide, and Amiodarone: Correlations with Clinical Effects and Antiarrhythmic Actions a

  1984cited by this paper
• Torsade de pointes: the long-short initiating sequence and other clinical features: observations in 32 patients.

  1983cited by this paper
• Bradycardia-dependent triggered activity: relevance to drug-induced multiform ventricular tachycardia.

  1983cited by this paper
• Amiodarone in refractory life-threatening ventricular arrhythmias.

  1983cited by this paper
• Polymorphous ventricular tachycardia associated with normal and long Q-T intervals.

  1982cited by this paper
• Clinical efficacy and electrophysiology during long-term therapy for recurrent ventricular tachycardia or ventricular fibrillation.

  1981cited by this paper
• Etiology, Warning Signs and Therapy of Torsade de Pointes: A Study of 10 Patients

  1981cited by this paper
• "Les torsades de pointes": an unusual ventricular arrhythmia.

  1980cited by this paper
• Amiodarone-induced ventricular fibrillation.

  1980cited by this paper
• Preeminence of the Left Stellate Ganglion in the Long Q-T Syndrome

  1979cited by this paper
• Stellectomy and exercise in man

  1979cited by this paper
• Effects of Unilateral Stellectomy upon Cardiac Performance during Exercise in Dogs

  1979cited by this paper
• De subitaneis mortibus. XXX. Observations on the pathophysiology of the long QT syndromes with special reference to the neuropathology of the heart.

  1978cited by this paper
• ["T'orsade de pointe" and amiodarone (author's transl)].

  1978cited by this paper
• Quinidine-induced ventricular flutter and fibrillation without digitalis therapy.

  1976cited by this paper
• Nonuniform Recovery of Excitability in Ventricular Muscle

  1964cited by this paper

• Drug-induced Torsades de pointes: Insights from a canine model of chronic atrioventricular block.

  2026cites this paper
• Reassessing the Conduct of Patch Clamp Cardiac Ion Channel Assays to Improve Nonclinical Data Translation to Clinical ECG Changes and Proarrythmia Risk

  2025cites this paper
• Integrating drug effects on individual cardiac ionic currents and cardiac action potentials to understand nonclinical translation to clinical ECG changes

  2025cites this paper
• Amiodarone prevents wave front-tail interactions in patients with heart failure: an in silico study

  2023cites this paper
• Pharmacologic Management for Ventricular Arrhythmias: Overview of Anti-Arrhythmic Drugs

  2022influential citation
• Extreme QT Interval Prolongation and Helicoid Ventricular Tachycardia ( Torsade de Pointes ) in Non-ST-Elevation Acute Coronary Syndrome

  2022cites this paper
• Extreme QT Interval Prolongation and Helicoid Ventricular Tachycardia ( Torsade de Pointes ) in Non-ST-Elevation Acute Coronary Syndrome

  2022cites this paper
• Utility of Zebrafish Models of Acquired and Inherited Long QT Syndrome

  2021cites this paper
• Prolonged QT with Multiple-Causation and its Succesful Multistage Therapy

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• Rabbit models as tools for preclinical cardiac electrophysiological safety testing: Importance of repolarization reserve.

  2016cites this paper
• Adverse Reactions of Amiodarone on the Thyroid

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• Double jeopardy.

  2013cites this paper
• Enhanced prediction and prevention of drug-induced torsades de pointes

  2013cites this paper
• The electro‐mechanical window in anaesthetized guinea pigs: a new marker in screening for Torsade de Pointes risk

  2012cites this paper
• Proarrhythmic potential of amiodarone: an underestimated risk?

  2012cites this paper
• Proarrhythmic potential of amiodarone: an underestimated risk?

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• Amiodarone for the treatment and prevention of ventricular fibrillation and ventricular tachycardia

  2010cites this paper
• Adherence to Amiodarone Monitoring Recommendations Before and After Implementation of a Centralized Pharmacy Service

  2010cites this paper
• Amiodarone for the Emergency Care of Children

  2010cites this paper
• Torsade de Pointes related to the co-administration of amiodarone and digoxin

  2009cites this paper
• L-type calcium current recovery versus ventricular repolarization: preserved membrane-stabilizing mechanism for different QT intervals across species.

  2008cites this paper
• Preclinical assessment of drug-induced proarrhythmias: role of the arterially perfused rabbit left ventricular wedge preparation.

  2008cites this paper
• Drug-induced QT-interval prolongation and proarrhythmic risk in the treatment of atrial arrhythmias.

  2007cites this paper
• Sudden Cardiac Death

  2006cites this paper
• Use of arterially perfused rabbit ventricular wedge in predicting arrhythmogenic potentials of drugs.

  2006cites this paper
• Blinded validation of the isolated arterially perfused rabbit ventricular wedge in preclinical assessment of drug-induced proarrhythmias.

  2006cites this paper
• Assessing the proarrhythmic potential of drugs: current status of models and surrogate parameters of torsades de pointes arrhythmias.

  2006cites this paper
• Mechanisms underlying arrhythmogenesis in long QT syndrome.

  2005cites this paper
• Beat-to-Beat variability of repolarization determines proarrhythmic outcome in dogs susceptible to drug-induced torsades de pointes.

  2005cites this paper
• Refining detection of drug-induced proarrhythmia: QT interval and TRIaD.

  2005cites this paper
• 第18回 犬山不整脈カンファランス テーマII「III群薬ニフェカラントとソタロール」

  2004cites this paper
• Comparison of the In Vitro Electrophysiologic and Proarrhythmic Effects of Amiodarone and Sotalol in a Rabbit Model of Acute Atrioventricular Block

  2004cites this paper
• In Vivo and In Vitro Characterization of the Novel Antiarrhythmic Agent SSR149744C: Electrophysiological, Anti-Adrenergic, and Anti-Angiotensin II Effects

  2004cites this paper
• 第18回 犬山不整脈カンファランス テーマII「III群薬ニフェカラントとソタロール」

  2004cites this paper
• Micro-Electrode Arrays in Cardiac Safety Pharmacology

  2004cites this paper
• Tridimensional activation patterns of acquired torsade-de-pointes-tachycardias in dogs with chronic AV-block

  2004cites this paper
• Prevention of clofilium-induced torsade de pointes by prostaglandin E2 does not involve ATP-dependent K+ channels.

  2003cites this paper
• Electrophysiologic Characterization of Dronedarone in Guinea Pig Ventricular Cells

  2003cites this paper
• Drug Block of I Kr : Model Systems and Relevance to Human Arrhythmias

  2001cites this paper
• Chronic Amiodarone Evokes No Torsade de Pointes Arrhythmias Despite QT Lengthening in an Animal Model of Acquired Long-QT Syndrome

  2001cites this paper
• Task Force on Sudden Cardiac Death of the European Society of Cardiology.

  2001cites this paper
• Torsade de pointes induced by intravenous and long-term oral amiodarone therapy in a patient with dilated cardiomyopathy.

  2001cites this paper
• Chemical Cardioversion of Atrial Fibrillation or Flutter With Ibutilide in Patients Receiving Amiodarone Therapy

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  2000cites this paper
• Polymorphic Ventricular Tachycardia and Long QT Syndromes

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  2000cites this paper
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  2000cites this paper
• Drug Interactions with Cisapride

  2000cites this paper
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  1999cites this paper
• Antiarrhythmic drug initiation in patients with atrial fibrillation.

  1999cites this paper
• Evaluation of the acute electrophysiologic effects of intravenous dronedarone, an amiodarone-like agent, with special emphasis on ventricular repolarization and acquired torsade de pointes arrhythmias.

  1999cites this paper
• Impact of structural heart disease on the selection of class III antiarrhythmics for the prevention of atrial fibrillation and flutter.

  1998cites this paper
• Optimal Management of Amiodarone Therapy: Efficacy and Side Effects

  1998cites this paper
• Different Effects of Amiodarone and Quinidine on the Homogeneity of Myocardial Refractoriness in Patients With Intraventricular Conduction Delay

  1998cites this paper
• Proarrhythmia: How to Assess and Manage It

  1998cites this paper
• Class III Antiarrhythmic Agents: The Next Wave

  1997cites this paper
• Polymorphic Ventricular Tachycardia: Primary Prevention, Immediate Evaluation & Management, Long-Term Management, and Experimental & Theoretical Developments

  1997cites this paper
• Pilot study and protocol of the Canadian Trial of Atrial Fibrillation (CTAF).

  1997cites this paper
• The Rational Use of Intravenous Amiodarone in the Perioperative Period

  1997cites this paper
• Torsade de pointes with amiodarone in a patient with previous torsade during beta-receptor blockade.

  1997cites this paper
• Amiodarone Induced Torsades de Pointes with Excessive QT Dispersion Following Quinidine Induced Polymorphic Ventricular Tachycardia

  1997cites this paper
• Emerging Class III Antiarrhythmic Agents:Mechanism of Action and Proarrhythmic Potential

  1997cites this paper
• Antiarrhythmic Drug Therapy in the Management of Atrial Fibrillation

  1997cites this paper
• Proarrhythmia during drug treatment of supraventricular tachycardia: paradoxical risk of sinus rhythm for sudden death.

  1996cites this paper
• Amiodarone Therapy After Previous Sotalol-induced Torsade de Pointes: Analysis of QT Dispersion to Predict Proarrhythmia

  1996cites this paper
• [Torsade de pointes during quinidine and amiodarone therapy].

  1996cites this paper
• Effective use of magnesium for acquired torsade de pointes in a 4-month-old infant

  1995cites this paper
• Electrophysiologic Mechanisms of the Long QT Interval Syndromes and Torsade de Pointes

  1995cites this paper
• Amiodarone for the Maintenance of Sinus Rhythm in Patients with Atrial Fibrillation

  1995cites this paper
• Prevention of class III-induced proarrhythmias by flecainide in an animal model of the acquired long QT syndrome.

  1995cites this paper
• Concentration dependent cardiotoxicity of terodiline in patients treated for urinary incontinence.

  1995cites this paper
• Amiodarone and torsades de pointes in patients with advanced heart failure.

  1995cites this paper
• Value and Risk of Class I and III Antiarrhythmic Drugs

  1994cites this paper
• Drug-Induced Torsade de Pointes

  1994cites this paper
• Risks and benefits of antiarrhythmic therapy.

  1994cites this paper
• Managing Chronic Atrial Fibrillation: A Markov Decision Analysis Comparing Warfarin, Quinidine, and Low-Dose Amiodarone

  1994cites this paper
• [Amiodarone therapy after sotalol-induced torsade de pointes: prolonged QT interval and QT dispersion in differentiation of pro-arrhythmic effects].

  1994cites this paper
• Amiodarone-associated Proarrhythmic Effects: A Review with Special Reference to Torsade de Pointes Tachycardia

  1994cites this paper
• Drugs, QT interval abnormalities and ventricular arrhythmias.

  1994cites this paper
• Drug effects on the electrocardiogram. A review of their clinical importance.

  1993cites this paper
• Rate-corrected QT interval: techniques and limitations.

  1993cites this paper
• Current status of class III antiarrhythmic drug therapy.

  1993cites this paper
• Antiarrhythmic drugs and torsade de pointes.

  1993cites this paper
• Comparative mechanisms of action of antiarrhythmic drugs.

  1993cites this paper
• Proarrhythmic effects of the class III agent almokalant: importance of infusion rate, QT dispersion, and early afterdepolarisations.

  1993cites this paper
• Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs.

  1993cites this paper
• Drug Effects on the Electrocardiogram

  1993cites this paper
• ['Cardiac ballet' with and without amiodarone].

  1993cites this paper
• Early after-depolarizations and torsade de pointes: implications for the control of cardiac arrhythmias by prolonging repolarization.

  1993cites this paper
• Frequency-dependent electrophysiologic effects of amiodarone in humans.

  1993cites this paper
• Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs

  1993cites this paper
• [Torsade de pointes].

  1993cites this paper
• Torsade de pointes

  1993cites this paper
• Low-dose amiodarone for atrial fibrillation.

  1993cites this paper
• Amiodarone: Pharmacology, Clinical Actions, and Relationships Between Them

  1992cites this paper
• [Potassium channels and arrhythmia].

  1992cites this paper
• Fatal torsade de pointes occurring in a patient receiving intravenous vasopressin and nitroglycerin.

  1992cites this paper