Effect of Melatonin on Testicular Damage in Streptozotocin-Induced Diabetes Rats

No abstract is available for this paper.

• Publication year

  2008

• Venue

  European Surgical Research

• Publication date

  2008-02-26

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1159/000118032PMID 18303272
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Melatonin induces apoptosis in human neuroblastoma cancer cells

  2006cited by this paper
• Sexual behaviour, sperm quantity and quality after short-term streptozotocin-induced hyperglycaemia in rats.

  2006cited by this paper
• Protective effect of melatonin against maternal deprivation-induced acute hippocampal damage in infant rats.

  2006cited by this paper
• Effect of di-(2-ethylhexyl) phthalate on N-cadherin and catenin protein expression in rat testis.

  2006cited by this paper
• Melatonin increases survival of HaCaT keratinocytes by suppressing UV‐induced apoptosis

  2006cited by this paper
• Protective effect of melatonin against head trauma-induced hippocampal damage and spatial memory deficits in immature rats.

  2005cited by this paper
• Melatonin mitigates mitochondrial malfunction

  2005cited by this paper
• Allopurinol provides long‐term protection for experimentally induced testicular torsion in a rabbit model

  2005cited by this paper
• Ultrastructural evaluation of the radioprotective effects of melatonin against X‐ray‐induced skin damage in Albino rats

  2005cited by this paper
• Melatonin Prevents Oxidative Stress and Hepatocyte Cell Death Induced by Experimental Cholestasis

  2004cited by this paper
• Antioxidant activity of melatonin in Chinese hamster ovarian cells: changes in cellular proliferation and differentiation.

  2003cited by this paper
• N-acetylcysteine reduces malondialdehyde levels in chronic hemodialysis patients--a pilot study.

  2003cited by this paper
• Melatonin exerts a therapeutic effect on cholestatic liver injury in rats with bile duct ligation

  2003cited by this paper
• Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans.

  2002cited by this paper
• Melatonin and N-acetylserotonin inhibit leukocyte rolling and adhesion to rat microcirculation.

  2001cited by this paper
• Apoptotic germ-cell death and testicular damage in experimental diabetes: prevention by endothelin antagonism

  2000cited by this paper
• Actions of Melatonin in the Reduction of Oxidative Stress

  2000cited by this paper
• Serum androgen levels in adolescents with type 1 diabetes: Relationship to pubertal stage and metabolic control

  2000cited by this paper
• Hormonal and genetic control of germ cell apoptosis in the testis.

  1999cited by this paper
• Role of oxidative stress in diabetic complications: a new perspective on an old paradigm.

  1999cited by this paper
• Altered basement membrane synthesis in the testis after tissue injury.

  1998cited by this paper
• Reproductive effects of nontesticular illness.

  1998cited by this paper
• Stage-specific degeneration of germ cells in the seminiferous tubules of non-obese diabetic mice.

  1997cited by this paper
• Effect of diabetes mellitus upon male reproductive function.

  1997cited by this paper
• Induction of apoptosis in the germ cells of adult male rats after exposure to cyclophosphamide.

  1997cited by this paper
• Melatonin prevents changes in microsomal membrane fluidity during induced lipid peroxidation

  1997cited by this paper
• Effects of endothelin-1 on the rat testicular vasculature.

  1996cited by this paper
• Oxidative Stress and Diabetic Vascular Complications

  1996cited by this paper
• Oxidative stress as a mediator of apoptosis.

  1994cited by this paper
• Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

  1992cited by this paper
• Spermatogonial apoptosis has three morphologically recognizable phases and shows no circadian rhythm during normal spermatogenesis in the rat

  1992cited by this paper
• Lipid peroxidation and retinopathy in streptozotocin-induced diabetes.

  1991cited by this paper
• Effects of the pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture.

  1988cited by this paper
• The effect of streptozotocin-induced diabetes on the neuroendocrine-male reproductive tract axis of the adult rat.

  1987cited by this paper
• Hormonal control of pubertal spermatogenesis.

  1987cited by this paper
• Recent studies on the structure and pathology of basement membranes

  1986cited by this paper
• Interstitial compartment pathology and spermatogenic disruption in testes from impotent diabetic men

  1985cited by this paper
• STRUCTURE OF BASEMENT MEMBRANE IN NORMAL AND DIABETIC TISSUE

  1982cited by this paper
• Cell death: the significance of apoptosis.

  1980cited by this paper
• Testicular lesions of streptozotocin diabetic rats.

  1975cited by this paper
• Testicular biopsy score count--a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males.

  1970cited by this paper

• Sitagliptin alleviates cyclophosphamide-induced oxidative stress and testicular toxicity in Wistar rats

  2026cites this paper
• Vitamin D alleviates chronic stress-induced testicular steroidogenesis disruption in Wistar rats.

  2025cites this paper
• Isolated gastric perforation following blunt abdominal trauma: A case report

  2025cites this paper
• Vitamin D supplementation stimulates germ cell proliferation in a restraint-stressed mouse.

  2025cites this paper
• Metabolic intervention restores fertility and sperm health in non-obese diabetic rats

  2025cites this paper
• Evaluation of Effect of Montelukast in the Model of Streptozotocin Induced Diabetic Nephropathy in Rats

  2024cites this paper
• The potential protective effect of propolis on diabetic nephropathy induced by streptozotocin in adult albino rats

  2024cites this paper
• Morin hydrate ameliorates heat-induced testicular impairment in a mouse model

  2024cites this paper
• Effects of sitagliptin and L-theanine combination therapy on testicular tissue in rats with experimental diabetes.

  2024cites this paper
• Ameliorating diabetes‐induced testicular dysfunction by modulating PKC/Nrf2/Bcl‐2 signaling: Protective role of sulbutiamine

  2024cites this paper
• Differential effect of visfatin inhibition on the testicular androgen and estrogen receptors expression in early pubertal mice

  2024cites this paper
• Intra-testicular visfatin inhibition disrupts androgen and estrogen signalling in the mouse testis.

  2024cites this paper
• Evidence of the inhibitory role of visfatin in the testicular activity of mice during the infantile stage.

  2023cites this paper
• Protective effects of melatonin on DEHP‐induced apoptosis and oxidative stress in prepubertal testes via the PI3K/AKT pathway

  2023cites this paper
• Antioxidant, antiapoptotic, and antifibrotic abilities of L-Arginine ameliorate the testicular dysfunction in diabetic rats.

  2023cites this paper
• Protective effects of melatonin against oxidative stress induced by metabolic disorders in the male reproductive system: a systematic review and meta-analysis of rodent models

  2023cites this paper
• Effects of electroacupuncture at ST36 and BL20 on the diabetic rat testis

  2023cites this paper
• Melatonin Ameliorates Diquat-Induced Testicular Toxicity via Reducing Oxidative Stress, Inhibiting Apoptosis, and Maintaining the Integrity of Blood-Testis Barrier in Mice

  2023cites this paper
• Effect of sleeve gastrectomy on sperm quality and fertility on non-obese diabetes diet model rat

  2023cites this paper
• The renoprotective effects of taurine against diabetic nephropathy via the p38 MAPK and TGF-β/Smad2/3 signaling pathways

  2023influential citation
• Histological and Immunohistochemical Examination in Testicular Tissue of Diabetic Rats Treated with Dandelion (Taraxacum officinale) Extract

  2023cites this paper
• Combined effect of ethanolic leaf extracts of Carica papaya and Newbouldia laevis on the histology of testes of Alloxan-induced diabetic rats

  2023cites this paper
• Protective properties of Rydingia persica in reproductive complications induced by diabetes in male rats: An experimental study

  2022cites this paper
• Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats

  2022cites this paper
• Evaluation of a single dose of intra‐testicular insulin treatment in heat‐stressed mice model

  2022cites this paper
• Effect of melatonin and nitric oxide on capacitation and apoptotic changes induced by epidermal growth factor in ram sperm.

  2022cites this paper
• Overview of biological effects of melatonin on testis: A review

  2022cites this paper
• The antioxidant effects of hydroalcoholic extract of Ashrasi date palm on sperm parameters and DNA fragmentation in diabetic rats

  2022cites this paper
• A systematic review on the role of melatonin and its mechanisms on diabetes-related reproductive impairment in non-clinical studies

  2022influential citation
• Study the effect of genistein on reproductive functions in male diabetic rats

  2022cites this paper
• Treatment of copper nanoparticles (CuNPs) for two spermatogenic cycles impairs testicular activity via down-regulating steroid receptors and inhibition of germ cell proliferation in a mice model

  2022cites this paper
• Testicular ultrastructure and hormonal changes following administration of tenofovir disoproxil fumarate-loaded silver nanoparticle in type-2 diabetic rats

  2022cites this paper
• Effect of Hydroethanolic Extract of Nasturtium on Parameters of Reproductive and Sex Hormones of Male Rats

  2021cites this paper
• The effect of etanercept and anakinra on experimental type 2 diabetes pathology in rats

  2021cites this paper
• Effects of ellagic acid in the testes of streptozotocin induced diabetic rats

  2021cites this paper
• Effect of Probiotics Bifidobacterium lactis And Lactobacillus casei on SpermParameters and Expression of Apoptosis BAX and Bcl2 Genes in Streptozotocin-Induced Diabetic Rats

  2021cites this paper
• Rescue effect of sodium acetate in diabetes mellitus-associated testicular dysfunction is accompanied by PCSK9 modulation.

  2021cites this paper
• Sitagliptin and fucoidan prevent apoptosis and reducing ER stress in diabetic rat testes

  2021influential citation
• Echinacea purpurea Ethanol Extract Improves Male Reproductive Dysfunction With Streptozotocin–Nicotinamide-Induced Diabetic Rats

  2021cites this paper
• Evaluation of the Antihyperlipidemic and Antioxidant Effects of Catharanthus roseus Extracted from Vinca minor in Diabetic Rats

  2021cites this paper
• Quercetin and vitamin E attenuate diabetes‐induced testicular anomaly in Wistar rats via the mitochondrial‐mediated apoptotic pathway

  2021cites this paper
• Synthetic leptin c-fragment peptide minimises heat-induced impairment of spermatogenesis in mice via Stat3 signalling.

  2021cites this paper
• Ellagic acid improved diabetes mellitus-induced testicular damage and sperm abnormalities by activation of Nrf2

  2021cites this paper
• The therapeutic role of lactobacillus and montelukast in combination with metformin in diabetes mellitus complications through modulation of gut microbiota and suppression of oxidative stress.

  2021cites this paper
• Co-treatment of testosterone and estrogen mitigates heat-induced testicular dysfunctions in a rat model.

  2021cites this paper
• Sustained In Vitro and In Vivo Delivery of Metformin from Plant Pollen-Derived Composite Microcapsules

  2021cites this paper
• Properties of Solanum melongena green calyx against toxic effects of diabetes‐induced testopathy: a stereological and biochemical study

  2021cites this paper
• The protective effect of metformin against testicular damage in diabetes and prostate cancer model

  2021cites this paper
• Novel enhancer for male fertility dysfunction in STZ diabetic rats

  2021cites this paper
• Diabetes-induced glucolipotoxicity impairs wound healing ability of adipose-derived stem cells-through the miR-1248/CITED2/HIF-1α pathway

  2020cites this paper
• Can troxerutin pretreatment prevent testicular complications in prepubertal diabetic male rats?

  2020cites this paper
• Comparative proteomics reveals protective effect of resveratrol on a high-fat diet-induced damage to mice testis

  2020cites this paper
• Melatonin, antioxidant capacity, and male reproductive function

  2020cites this paper
• Protective Effects of Zinc Supplement on Chromatin Deficiency and Sperm Parameters in Streptozotocin-Induced Diabetic Rats

  2020cites this paper
• Protective action of melatonin on diabetic rat testis at cellular, hormonal and immunohistochemical levels.

  2020cites this paper
• Melatonin protects the mouse testis against heat-induced damage.

  2020cites this paper
• Postmortem histochemical and electron microscopic changes in skeletal muscle fibers of fatal hypothermia: an experimental study

  2020cites this paper
• Blockade of Toll-like receptor 4 (TLR4) reduces oxidative stress and restores phospho-ERK1/2 levels in Leydig cells exposed to high glucose.

  2020cites this paper
• Melatonin reverses cognitive deficits in streptozotocin-induced type 1 diabetes in the rat through attenuation of oxidative stress and inflammation.

  2020cites this paper
• Effect of Resistance and Endurance Trainings on Sperm Parameters and Spermatogenesis Indices in Type 2 Diabetic Rats

  2020cites this paper
• PERBEDAAN KUALITAS SPERMA PADA PASIEN PENDERITA DIABETES MELLITUS TIPE 1 DAN 2 DI RSUD. LAMADUKELLENG, SENGKANG, SULAWESI SELATAN

  2020cites this paper
• Comparative Protective Effects of N-Acetylcysteine, and Melatonin against Obesity- Induced Testicular Dysfunction in Rats.

  2020cites this paper
• Effects of Icariin on Histomorphometric Changes of Testis and Prostate Induced by Acrylamide in Mice

  2020cites this paper
• Benefits of the consumption of Brazil nut (Bertholletia excelsa) extract in male reproductive parameters of streptozotocin-induced diabetic rats

  2020cites this paper
• Fukoidanın Diyabetik Sıçan Testis Dokularındaki PCNA, INSL3, JNK, TGF-β1, IL-1β ve Akt İfadelerine Etkisi

  2020cites this paper
• Effect of Platelet-Rich Plasma (PRP) on testicular damage in streptozotocin-induced diabetic rats

  2020cites this paper
• Preventative Effects of Vitamin E on Testicular Damage and Sperm Parameters in the First-Generation Mice Pups due to Pre- and Postnatal Mancozeb Exposure

  2019cites this paper
• Potency of mangosteen (Garcinia mangostana L.) pericarp on seminiferous tubules testes streptozotocin-induced diabetic rats

  2019cites this paper
• IMMUNOHISTOCHEMICAL ANALYSIS OF SFLT-1 AND ADAMTS-8 EXPRESSION IN DIABETIC RAT TESTIS TISSUE

  2019cites this paper
• Synergistic effect of Aloe vera and Vitamin C in regulating the steroidogenic and spermatogenic abnormalities of streptozotocin induced male diabetic rats.

  2019cites this paper
• An Experimental Study to Evaluate the Protective Effects of Solanum lycopersicum Seed Essential Oil on Diabetes-Induced Testicular Injuries

  2019cites this paper
• Investigation the Spermatogenesis and Testis Structure in Diabetic Rats After Treatment With Galega officinalis Extract

  2019cites this paper
• Wenshen Jianpi recipe, a blended traditional Chinese medicine, ameliorates proteinuria and renal injury in a rat model of diabetic nephropathy

  2019cites this paper
• Resveratrol and dimethyl fumarate ameliorate testicular dysfunction caused by chronic unpredictable mild stress-induced depression in rats.

  2019cites this paper
• Pharmacological effect of Allium sativum on coagulation, blood pressure, diabetic nephropathy, neurological disorders, spermatogenesis, antibacterial effects

  2019cites this paper
• Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model.

  2019cites this paper
• Effects of L-Carnitine on the sperm parameters disorders, apoptosis of spermatogenic cells and testis histopathology in diabetic Rats

  2019cites this paper
• Effects of Crocin on Sperm Parameters and Seminiferous Tubules in Diabetic Rats

  2019cites this paper
• Testicular toxicity and reproductive performance of streptozotocin-induced diabetic male rats: the ameliorating role of silymarin as an antioxidant

  2019cites this paper
• Effect of crocin on biochemical parameters, oxidative/antioxidative profiles, sperm characteristics and testicular histopathology in streptozotocin-induced diabetic rats

  2019cites this paper
• Ameliorative effect of combined low dose of Pioglitazone and omega‐3 on spermatogenesis and steroidogenesis in diabetic rats

  2019cites this paper
• Protective efficiency of Ashrasi date palm hydroalcoholic extract against diabetes‐induced testicular toxicity: A biochemical and stereological study

  2019cites this paper
• Preconditioning with atorvastatin against renal ischemia-reperfusion injury in nondiabetic versus diabetic rats.

  2019cites this paper
• Effects of Sancai Lianmei Particle on autophagy and apoptosis in testes of diabetic mice via the Nrf 2 / HO-1 pathway

  2019cites this paper
• Comparative effects of glibenclamide, metformin and insulin on fetal pancreatic histology and maternal blood glucose in pregnant streptozotocin-induced diabetic rats

  2019cites this paper
• Rescue effects of prenatal melatonin administration against bisphenol A- induced perturbations of reproductive and thyroid activities in male rat offsprings

  2019cites this paper
• Effect of Diabetes on the Male Reproductive System—A Histomorphological Study

  2019cites this paper
• Examination of the immunohistochemical localization and gene expression by RT-PCR of the oxytocin receptor in diabetic and non-diabetic mouse testis

  2018cites this paper
• Vitamin E improves testicular damage in streptozocin‐induced diabetic rats, via increasing vascular endothelial growth factor and poly(ADP‐ribose) polymerase‐1

  2018cites this paper
• The Effect of High Intensity Interval Training on Hormonal Hypothalamic-Pituitary-Gonadal Axisand Fertility in Type 2 Diabetic Male Rats

  2018cites this paper
• Hyperglycemia induced testicular damage in type 2 diabetes mellitus rats exhibiting microcirculation impairments associated with vascular endothelial growth factor decreased via PI3K/Akt pathway

  2018cites this paper
• The Effect of Metformin versus Vitamin E on the Testis of Adult Diabetic Albino Rats: Histological, Biochemical and Immunohistochemistry Study

  2018cites this paper
• Statins reduce testicular and ocular VEGF: A potential compromise to microcirculation.

  2018cites this paper
• Histo-morphological and seminal evaluation of testicular parameters in diabetic rats under antiretroviral therapy: interactions with Hypoxis hemerocallidea

  2018influential citation
• Effects of melatonin treatment on the spermatogenesis and serum inflammatory cytokine levels in diabetic rats

  2018influential citation
• Melatonin protects prepuberal testis from deleterious effects of bisphenol A or diethylhexyl phthalate by preserving H3K9 methylation

  2018cites this paper
• Effects of Dexmedetomidine on Renal Ischaemia Reperfusion Injury in Streptozotocin-Induced Diabetic Rats.

  2018cites this paper
• The protective role of melatonin and curcumin in the testis of young and aged rats

  2018cites this paper
• Responses to the Bioactive Component of Crassocephalum crepidioides on Histomorphology, Spermatogenesis and Steroidogenesis in Streptozotocin-Induced Diabetic Male Rats

  2018cites this paper
• Hypoxis hemerocallidea alters metabolic parameters and hepatic histomorphology in streptozotocin-nicotinamide-induced diabetic male rats under antiretroviral therapy

  2018cites this paper