Retracted: Transrepression by a liganded nuclear receptor via a bHLH activator through co‐regulator switching

No abstract is available for this paper.

• Publication year

  2004

• Venue

  EMBO Journal

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.emboj.7600157PMID 15934135PMCID PMC391066
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.

  2003influential reference
• Nuclear receptors: a rendezvous for chromatin remodeling factors.

  2003cited by this paper
• Cloning, gene structure and dietary regulation of the type-IIc Na/Pi cotransporter in the mouse kidney

  2003cited by this paper
• Nuclear receptor function requires a TFTC-type histone acetyl transferase complex.

  2002cited by this paper
• Combinatorial control of gene expression by nuclear receptors and coregulators.

  2002cited by this paper
• Combinatorial Control of Gene Expression by Nuclear Receptors and Coregulators

  2002cited by this paper
• A Transcriptional Switch Mediated by Cofactor Methylation

  2001cited by this paper
• A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA.

  2001cited by this paper
• Targeted ablation of the 25-hydroxyvitamin D 1α-hydroxylase enzyme: Evidence for skeletal, reproductive, and immune dysfunction

  2001cited by this paper
• Regulation of CLOCK and MOP4 by nuclear hormone receptors in the vasculature: a humoral mechanism to reset a peripheral clock.

  2001cited by this paper
• Estrogen Receptor Binding to DNA Is Not Required for Its Activity through the Nonclassical AP1 Pathway*

  2001cited by this paper
• The coregulator exchange in transcriptional functions of nuclear receptors.

  2000influential reference
• Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

  1999cited by this paper
• The Autonomous Transactivation Domain in Helix H3 of the Vitamin D Receptor Is Required For Transactivation and Coactivator Interaction*

  1999cited by this paper
• Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators.

  1999cited by this paper
• Selective Interaction of Vitamin D Receptor with Transcriptional Coactivators by a Vitamin D Analog

  1999cited by this paper
• Positive and negative regulations of the renal 25-hydroxyvitamin D3 1alpha-hydroxylase gene by parathyroid hormone, calcitonin, and 1alpha,25(OH)2D3 in intact animals.

  1999cited by this paper
• No enzyme activity of 25-hydroxyvitamin D3 1alpha-hydroxylase gene product in pseudovitamin D deficiency rickets, including that with mild clinical manifestation.

  1999cited by this paper
• The promoter of the human 25-hydroxyvitamin D3 1 alpha-hydroxylase gene confers positive and negative responsiveness to PTH, calcitonin, and 1 alpha,25(OH)2D3.

  1998cited by this paper
• The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen.

  1998cited by this paper
• The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed

  1998cited by this paper
• Parathyroid hormone activation of the 25-hydroxyvitamin D3-1alpha-hydroxylase gene promoter.

  1998influential reference
• A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression

  1997cited by this paper
• Steroid receptor coactivator-1 is a histone acetyltransferase

  1997cited by this paper
• 25-Hydroxyvitamin D3 1alpha-hydroxylase and vitamin D synthesis.

  1997cited by this paper
• Mutations in the 1,25-Dihydroxyvitamin D3 Receptor Identifying C-terminal Amino Acids Required for Transcriptional Activation That Are Functionally Dissociated from Hormone Binding, Heterodimeric DNA Binding, and Interaction with Basal Transcription Factor IIB, in Vitro *

  1997cited by this paper
• Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

  1997cited by this paper
• DNA sequences in the rat parathyroid hormone-related peptide gene responsible for 1,25-dihydroxyvitamin D3-mediated transcriptional repression.

  1996cited by this paper
• Intron retention generates a novel isoform of the murine vitamin D receptor that acts in a dominant negative way on the vitamin D signaling pathway

  1996cited by this paper
• A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors.

  1996cited by this paper
• Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

  1996cited by this paper
• A decade of molecular biology of retinoic acid receptors

  1996cited by this paper
• The Pan basic helix-loop-helix proteins are required for insulin gene expression.

  1995cited by this paper
• Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

  1995cited by this paper
• Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

  1995cited by this paper
• A transcriptional co-repressor that interacts with nuclear hormone receptors

  1995cited by this paper
• Steroid hormone receptors: many actors in search of a plot.

  1995cited by this paper
• The nuclear receptor superfamily: the second decade.

  1995cited by this paper
• Phosphorylated CREB binds specifically to the nuclear protein CBP

  1993cited by this paper
• Sequences in the human parathyroid hormone gene that bind the 1,25-dihydroxyvitamin D3 receptor and mediate transcriptional repression in response to 1,25-dihydroxyvitamin D3.

  1992influential reference
• Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo.

  1991cited by this paper
• The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation.

  1990cited by this paper
• Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.

  1990cited by this paper
• TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

  1990cited by this paper
• Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities.

  1989cited by this paper
• Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence.

  1989cited by this paper
• Cooperative effects of colony-stimulating factor 1 and recombinant interleukin 2 on proliferation and induction of cytotoxicity of macrophage precursors generated from mouse bone marrow cell cultures

  1989cited by this paper
• A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins.

  1989cited by this paper
• The human estrogen receptor has two independent nonacidic transcriptional activation functions.

  1989cited by this paper
• Parathyroid hormone modulation of 25-hydroxyvitamin D3 metabolism by cultured chick kidney cells is mimicked and enhanced by forskolin.

  1985influential reference

• p300 Maintains Primordial Follicle Activation by Repressing VEGFA Transcription.

  2024cites this paper
• Vitamin D metabolism is altered during aging alone or combined with obesity in male mice

  2024cites this paper
• Interaction of Vitamin D with Peptide Hormones with Emphasis on Parathyroid Hormone, FGF23, and the Renin-Angiotensin-Aldosterone System

  2022cites this paper
• Structure and function of the vitamin D-binding proteins

  2020cites this paper
• Nuclear Receptors and Epigenetic Regulation

  2019cites this paper
• EPIGENETIC MODIFICATION OF VITAMIN D-INDUCED GENE EXPRESSION IN HUMAN COLORECTAL AND BREAST CANCER CELL LINES

  2018cites this paper
• Antiproliferative Effects of 1α-OH-vitD3 in Malignant Melanoma: Potential Therapeutic implications

  2017cites this paper
• IGFBP-3 Interacts with the Vitamin D Receptor in Insulin Signaling Associated with Obesity in Visceral Adipose Tissue

  2017cites this paper
• MDM2 (Murine Double Minute 2 homolog) bindet und inhibiert den Vitamin D Rezeptor

  2016cites this paper
• Vitamin D and colorectal cancer: molecular, epidemiological and clinical evidence

  2016influential citation
• Post-transcriptional Mechanisms in Endocrine Regulation

  2016cites this paper
• Mechanistic Effects of Calcitriol in Cancer Biology

  2015cites this paper
• A cis-acting element in the promoter of human ether à go-go 1 potassium channel gene mediates repression by calcitriol in human cervical cancer cells.

  2015cites this paper
• The claudin‐16 channel gene is transcriptionally inhibited by 1,25‐dihydroxyvitamin D

  2015cites this paper
• Regulation of the vitamin D receptor gene by environment, genetics and epigenetics.

  2015cites this paper
• Vitamin D and its receptor during late development.

  2015cites this paper
• Epigenetic Regulation of Cytochrome P450 Enzymes and Clinical Implication.

  2015cites this paper
• MDM2 binds and inhibits vitamin D receptor

  2015influential citation
• Vitamin D and the epigenome

  2014cites this paper
• Inhibition of Methicillin-resistant Staphylococcus aureus-induced cytokines mRNA production in human bone marrow derived mesenchymal stem cells by 1,25-dihydroxyvitamin D3

  2014cites this paper
• Vitamin D Represses Dentin Matrix Protein 1 in Cementoblasts and Osteocytes

  2014cites this paper
• Genomic Determinants of Gene Regulation by 1,25-Dihydroxyvitamin D3 during Osteoblast-lineage Cell Differentiation*♦

  2014cites this paper
• Fundamentals of vitamin D hormone-regulated gene expression.

  2014cites this paper
• A Computational Analysis of Motif-Negative VDR-DNA Interaction and Possible Explanations of Its Mechanism of Interaction

  2014cites this paper
• Vitamin D as a regulator of steroidogenic enzymes

  2014cites this paper
• Genomic Binding Sites and Biological Effects of the Vitamin D: VDR Complex in Multiple Sclerosis

  2014cites this paper
• Non-classical mechanisms of transcriptional regulation by the vitamin D receptor: insights into calcium homeostasis, immune system regulation and cancer chemoprevention.

  2014influential citation
• Nuclear receptors and epigenetic regulation: opportunities for nutritional targeting and disease prevention.

  2014cites this paper
• Thyroid hormones decrease plasma 1α,25-dihydroxyvitamin D levels through transcriptional repression of the renal 25-hydroxyvitamin D3 1α-hydroxylase gene (CYP27B1).

  2013cites this paper
• Vitamin D Receptor Inhibits Nuclear Factor κB Activation by Interacting with IκB Kinase β Protein*

  2013cites this paper
• MiR-627 mediates the epigenetic mechanisms of vitamin D in suppression of colon cancer growth

  2013cites this paper
• Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: importance of mammary CYP27B1 for treatment and prevention.

  2013cites this paper
• Transrepression of the estrogen receptor promoter by calcitriol in human breast cancer cells via two negative vitamin D response elements.

  2013cites this paper
• Nuclear receptors in bone physiology and diseases.

  2013cites this paper
• Vitamin D analog EB1089 inhibits aromatase expression by dissociation of comodulator WSTF from the CYP19A1 promoter-a new regulatory pathway for aromatase.

  2013cites this paper
• Vitamin D receptor signaling mechanisms: integrated actions of a well-defined transcription factor.

  2013cites this paper
• The function of TCF4 in Pitt-Hopkins syndrome and schizophrenia

  2013cites this paper
• Vitamin D and colon cancer.

  2012cites this paper
• The first genome-wide view of vitamin D receptor locations and their mechanistic implications.

  2012cites this paper
• Characterization of the Autocrine/Paracrine Function of Vitamin D in Human Gingival Fibroblasts and Periodontal Ligament Cells

  2012cites this paper
• HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter.

  2012cites this paper
• - 1-Interference of E 2-2-mediated effect in endothelial cells by FAM 96 B through its limited expression of E 2-2

  2012cites this paper
• Genome-scale transcriptomic and epigenomic analysis of stem cells

  2012cites this paper
• Dietary vitamin D₃ and 1,25-dihydroxyvitamin D₃ (calcitriol) exhibit equivalent anticancer activity in mouse xenograft models of breast and prostate cancer.

  2012cites this paper
• Regulation of target gene expression by the vitamin D receptor - an update on mechanisms

  2012cites this paper
• Vitamin D: metabolism.

  2012cites this paper
• Regulation of intracrine production of 1,25-dihydroxyvitamin D and its role in innate immune defense against infection.

  2012cites this paper
• Action of Vitamin D and the Receptor, VDRa, in Calcium Handling in Zebrafish (Danio rerio)

  2012cites this paper
• Vitamin D resistance and colon cancer prevention.

  2012cites this paper
• Vitamin D-mediated regulation of CYP21A2 transcription - a novel mechanism for vitamin D action.

  2012cites this paper
• PIAS4 represses vitamin D receptor-mediated signaling and acts as an E3-SUMO ligase towards vitamin D receptor.

  2012cites this paper
• The Molecular Cancer Biology of the VDR

  2011cites this paper
• WSTF does it all: a multifunctional protein in transcription, repair, and replication.

  2011cites this paper
• Nuclear hormone 1α,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy

  2011cites this paper
• The growing role of gene methylation on endocrine function.

  2011cites this paper
• Omics Underpins Novel Clues on VDR Chemoprevention Target in Breast Cancer

  2011cites this paper
• 1,25-Dihydroxyvitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A

  2011cites this paper
• The Vitamin D3 1alpha-Hydroxylase Gene and Its Regulation by Active Vitamin D3

  2011cites this paper
• Interference of E2‐2‐mediated effect in endothelial cells by FAM96B through its limited expression of E2‐2

  2011cites this paper
• Adenovirus‐delivered microRNA targeting the vitamin D receptor reduces intracellular Ca2+ concentrations by regulating the expression of Ca2+‐transport proteins in renal epithelial cells

  2011cites this paper
• Williams syndrome is an epigenome-regulator disease.

  2011cites this paper
• Regulation of vitamin D metabolism.

  2011cites this paper
• Vitamin D metabolism and activity in the parathyroid gland.

  2011cites this paper
• Vitamin D inhibits NF-κB activation in B cells and controls the humoral immune response

  2011cites this paper
• Vitamin D metabolism within bone cells: effects on bone structure and strength.

  2011cites this paper
• Vitamin D in chronic kidney disease: new potential for intervention.

  2011cites this paper
• Negative Regulation of the Thyrotropin β Gene by Thyroid Hormone

  2011cites this paper
• 25-Dihydroxyvitamin D 3 Ameliorates Th 17 Autoimmunity via Transcriptional Modulation of Interleukin-17 A

  2011cites this paper
• Bone CYP27B1 gene expression is increased with high dietary calcium and in mineralising osteoblasts.

  2010cites this paper
• Hormonal gene regulation through DNA methylation and demethylation.

  2010cites this paper
• The down-regulation of the human MYC gene by the nuclear hormone 1alpha,25-dihydroxyvitamin D3 is associated with cycling of corepressors and histone deacetylases.

  2010cites this paper
• Genomics of long-range regulatory elements.

  2010cites this paper
• An emerging role for class I bHLH E2-2 proteins in EMT regulation and tumor progression

  2010cites this paper
• Primary effect of 1α,25(OH)₂D₃ on IL-10 expression in monocytes is short-term down-regulation.

  2010cites this paper
• Direct suppression of Pth gene expression by the vitamin D prohormones doxercalciferol and calcidiol requires the vitamin D receptor.

  2010cites this paper
• Vitamin D: metabolism.

  2010cites this paper
• Homéostasie du fer et traitement différenciant des leucémies aigües myéloblastiques

  2010cites this paper
• A Downstream Intergenic Cluster of Regulatory Enhancers Contributes to the Induction of CYP24A1 Expression by 1α,25-Dihydroxyvitamin D3*

  2010cites this paper
• Modulation of the vitamin D3 response by cancer-associated mutant p53.

  2010influential citation
• Calcitriol down-regulates human ether a go-go 1 potassium channel expression in cervical cancer cells.

  2010cites this paper
• EXPRESSION OF VITAMIN D TARGET GENES AND PROTEINS IN HUMAN OSTEOSARCOMA CELL LINE , 143 B , IN RESPONSE TO 1 α , 25-DIHYDROXYVITAMIN

  2010cites this paper
• Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the receptor in parathyroid physiology.

  2009cites this paper
• A genomic perspective on vitamin D signaling.

  2009cites this paper
• Consensus policies to solve bioinformatic problems through Bayesian network classifiers and estimation of distribution algorithms

  2009cites this paper
• DNA demethylation in hormone-induced transcriptional derepression

  2009cites this paper
• Regulation of the 5'-flanking region of the human CYP27B1 gene in osteoblast cells.

  2009cites this paper
• Calcitonin, a Regulator of the 25-Hydroxyvitamin D3 1α-Hydroxylase Gene*

  2009cites this paper
• Differential responsiveness of BmBR-C promoters to ecdysone signals

  2009cites this paper
• Nuclear receptor repression: regulatory mechanisms and physiological implications.

  2009cites this paper
• Retracted: CDP/cut is an osteoblastic coactivator of the vitamin D receptor (VDR)

  2009cites this paper
• The class I bHLH factors E2-2A and E2-2B regulate EMT

  2009cites this paper
• 25-Hydroxyvitamin D3 is a natural chemopreventive agent against carcinogen induced precancerous lesions in mouse mammary gland organ culture

  2008cites this paper
• Detecting reliable gene interactions by a hierarchy of Bayesian network classifiers

  2008cites this paper
• Vitamin D-Dependent Recruitment of Corepressors to Vitamin D/Retinoid X Receptor Heterodimers

  2008cites this paper
• Vitamin D and human health: lessons from vitamin D receptor null mice.

  2008cites this paper
• The Prostate 68 : 773 ^ 783 ( 2008 ) 1 a , 25-DihydroxyvitaminD 3 Down-Regulates Expressionof Prostate SpecificMembraneAntigen in ProstateCancerCells

  2008cites this paper
• Symposium on ‘ Diet and cancer ’ The vitamin D receptor in cancer

  2008cites this paper
• The vitamin D receptor in cancer

  2008cites this paper
• Extracellular calcium-sensing receptor activation induces vitamin D receptor levels in proximal kidney HK-2G cells by a mechanism that requires phosphorylation of p38alpha MAPK.

  2008cites this paper
• 1α,25‐Dihydroxyvitamin D3 down‐regulates expression of prostate specific membrane antigen in prostate cancer cells

  2008cites this paper