D-Pinitol and myo-Inositol Stimulate Translocation of Glucose Transporter 4 in Skeletal Muscle of C57BL/6 Mice

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Bioscience, biotechnology and biochemistry

• Publication date

  2010-05-23

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1271/bbb.90963PMID 20460718
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Diabetes, insulin resistance and sugars

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  1997cited by this paper
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  1997cited by this paper
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  1993cited by this paper
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