Neuroprotective effects of quercetin, rutin and okra (Abelmoschus esculentus Linn.) in dexamethasone-treated mice.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Neurochemistry International

• Publication date

  2011-10-01

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/j.neuint.2011.06.014PMID 21740943
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Antioxidative activities and phenolic content of extracts from okra (Abelmoschus esculentus L.).

  2010cited by this paper
• Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging.

  2008cited by this paper
• Peripheral injection of dexamethasone modulates anxiety related behaviors in mice: an interaction with opioidergic neurons.

  2008cited by this paper
• Long-term effects of prior cocaine exposure on Morris water maze performance.

  2008cited by this paper
• Glutamate and Neurotrophic Factors in Neuronal Plasticity and Disease

  2008cited by this paper
• Memory and learning impairment induced by dexamethasone in senescent but not young mice.

  2007cited by this paper
• Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats.

  2007cited by this paper
• Chronic Glucocorticoids Increase Hippocampal Vulnerability to Neurotoxicity under Conditions That Produce CA3 Dendritic Retraction But Fail to Impair Spatial Recognition Memory

  2007cited by this paper
• Physiology and neurobiology of stress and adaptation: central role of the brain.

  2007cited by this paper
• Protective effect of quercetin, a natural flavonoid against neuronal damage after transient global cerebral ischemia.

  2006cited by this paper
• Quercetin reverses D-galactose induced neurotoxicity in mouse brain.

  2006cited by this paper
• Stress and adult neurogenesis

  2006cited by this paper
• Glucocorticoids interact with emotion-induced noradrenergic activation in influencing different memory functions.

  2006cited by this paper
• A simple modification of the water maze test to enhance daily detection of spatial memory in rats and mice.

  2006cited by this paper
• Influence of dizocilpine (MK-801) on neurotoxic effect of dexamethasone: behavioral and histological studies.

  2006cited by this paper
• An improved method for the analysis of major antioxidants of Hibiscus esculentus Linn.

  2004cited by this paper
• Pharmacokinetics and metabolism of dietary flavonoids in humans.

  2004cited by this paper
• Dexamethasone inhibits proliferation of adult hippocampal neurogenesis in vivo and in vitro.

  2004cited by this paper
• Studies on the Flavonol Constituents of Abelmoschus manihot L. Medic

  2004cited by this paper
• Absorption and urinary excretion of quercetin, rutin, and alphaG-rutin, a water soluble flavonoid, in rats.

  2003cited by this paper
• The Exacerbation of Hippocampal Excitotoxicity by Glucocorticoids Is Not Mediated by Apoptosis

  2003cited by this paper
• Long‐lasting effects of neonatal dexamethasone treatment on spatial learning and hippocampal synaptic plasticity. Involvement of the NMDA receptor complex

  2003cited by this paper
• Neuroprotective effect of ACTH (4-9) in degeneration of hippocampal nerve cells caused by dexamethasone: morphological, immunocytochemical and ultrastructural studies.

  2003cited by this paper
• The mouse brain in stereotaxic coordinates

  2003cited by this paper
• Impaired spatial learning in the Morris water maze induced by serotonin reuptake inhibitors in rats

  2002cited by this paper
• Why New Neurons? Possible Functions for Adult Hippocampal Neurogenesis

  2002cited by this paper
• Opportunities for nutritional amelioration of radiation-induced cellular damage.

  2002cited by this paper
• Dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: implications for mood disorders.

  2001cited by this paper
• Protective effects and mechanism of total flavone of the flowers of Abelmoschl on the injury of myocardial ischemia

  2001cited by this paper
• Differential effects of dexamethasone and clenbuterol on rat growth and on beta2-adrenoceptors in lung and skeletal muscle.

  2000cited by this paper
• Dexamethasone enhances serum deprivation-induced necrotic death of rat C6 glioma cells through activation of glucocorticoid receptors.

  1999cited by this paper
• Dexamethasone augments ischemia-induced extracellular accumulation of glutamate in gerbil hippocampus.

  1998cited by this paper
• Dexamethasone Aggravates Ischemia-Induced Neuronal Damage by Facilitating the Onset of Anoxic Depolarization and the Increase in the Intracellular Ca2+ Concentration in Gerbil Hippocampus

  1998cited by this paper
• Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro.

  1997cited by this paper
• The acute effects of corticosteroids on cognition: integration of animal and human model studies.

  1997cited by this paper
• Detailed behavioral analysis of water maze acquisition under systemic NMDA or muscarinic antagonism: nonspatial pretraining eliminates spatial learning deficits.

  1996cited by this paper
• The effects of long-term corticosterone administration on hippocampal morphology and cognitive performance of middle-aged rats.

  1994cited by this paper
• Hippocampal function in the rat: Cognitive mapping or vicarious trial and error?

  1993cited by this paper
• Cortisone arrests growth but enhances the inductive effect of porcine growth hormone on plasma IGF-I concentrations in female rats.

  1991cited by this paper
• Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons.

  1990cited by this paper
• Developments of a water-maze procedure for studying spatial learning in the rat.

  1984cited by this paper

• Health benefits of okra (Abelmoschus esculentus) against diabetes mellitus and cognitive dysfunction: a review

  2025cites this paper
• Antioxidant properties and bioactive compounds in rooibos (Aspalathus linearis) and tea (Camellia sinensis) infusions

  2025cites this paper
• An Overview of the Current Scientific Evidence on the Biological Properties of Abelmoschus esculentus (L.) Moench (Okra)

  2025cites this paper
• STAT3 Suppression by Rutin Attenuates the Neurotoxic Effect of Pro-Inflammatory Microglia on Neurons Under Oxygen-Glucose Deprivation

  2025cites this paper
• Quercetin nanoemulsion ameliorates tremor and neuroinflammatory dysregulation: behavioral and molecular insights in a mouse model of essential tremor

  2025cites this paper
• Therapeutic Potential of Quercetin in the Treatment of Alzheimer’s Disease: In Silico, In Vitro and In Vivo Approach

  2025cites this paper
• Preventing Neurons and Glial Cells Destruction in Substantia Nigra Pars Compacta and Striatum Using St. John's Wort and Stem Cells on Parkinson's Model

  2025cites this paper
• Ethyl Acetate Fraction of Zanthoxylum bungeanum Ameliorates Cognitive Deficit by Facilitating the PHGDH-Dependent Astrocyte-Neuron Serine Shuttle in Aging Mice.

  2025cites this paper
• Abelmoschus esculentus Ameliorates Cognitive Impairment in Hyperlipidemic ApoE−/− Mice via Modulation of Oxidative Stress and Neuronal Differentiation

  2025cites this paper
• Molecular mechanisms of neuroprotective effect of rutin

  2025cites this paper
• Navigating neurological disorders: harnessing the power of natural compounds for innovative therapeutic breakthroughs

  2024cites this paper
• Origanum majorana L. polyphenols: in vivo antiepileptic effect, in silico evaluation of their bioavailability, and interaction with the NMDA receptor

  2024cites this paper
• Identification of Single Nucleotide Polymorphic Loci and Candidate Genes for Seed Germination Percentage in Okra under Salt and No-Salt Stresses by Genome-Wide Association Study

  2024cites this paper
• Prenatal Exposure to Quercetin Protects Against Methimazole‐Induced Reflexive Motor Behavior and Oxidative Stress Markers in Mouse Offspring

  2024cites this paper
• Could Searsia pentaphylla be a Source of New Bioactive Compounds? A Bibliometric Overview

  2024cites this paper
• Dried lemon peel extract improves memory and reduces anxiety-like behavior in rats exposed to chronic immobilization

  2024cites this paper
• Synergic fabrication of dual drug-loaded polymeric nanoparticles system to improve the in vitro treatment of glioma metastasis specific targeting therapy

  2024cites this paper
• Honey and Alzheimer’s Disease—Current Understanding and Future Prospects

  2023cites this paper
• Potential health benefits of the plant Levisticum officinale (lovage) in relation to its polyphenolic content

  2023cites this paper
• Zebrafish: A Model Deciphering the Impact of Flavonoids on Neurodegenerative Disorders

  2023cites this paper
• Metabolite fingerprinting and profiling of two locally cultivated edible plants by using nuclear magnetic resonance

  2023cites this paper
• Protective and therapeutic effects of okra seed in acute nontraumatic brain injury

  2023cites this paper
• Phytotherapeutic Potential of Rutin Against Xenobiotic-Induced Toxicities in Preclinical Models

  2023cites this paper
• The Effects of Abelmoschus esculentus (L.) Moench Seed on High Fat Diet Induced Metabolic and Cognitive Impairments in C57BL/6J Mice

  2023cites this paper
• Rutin intake mitigates the injury of blue light irradiation by altering aging rates of mortality in Drosophila model

  2023cites this paper
• Green Solvents-based Rutin Extraction from Sophora japonica L.

  2023cites this paper
• Potential of Quercetin to Protect Cadmium Induced Cognitive Deficits in Rats by Modulating NMDA-R Mediated Downstream Signaling and PI3K/AKT—Nrf2/ARE Signaling Pathways in Hippocampus

  2023cites this paper
• Neuropharmacological Interventions of Quercetin and Its Derivatives in Neurological and Psychological Disorders.

  2022cites this paper
• Plant-Derived Nanoscale-Encapsulated Antioxidants for Oral and Topical Uses: A Brief Review

  2022influential citation
• Effects of Quercetin and Resveratrol on Zinc Chloride- and Sodium Metavanadate-Induced Passive Avoidance Memory Retention Deficits in Male Mice

  2021cites this paper
• New Insights into the Antioxidant Compounds of Achenes and Sprouted Buckwheat Cultivated in the Republic of Moldova

  2021cites this paper
• Hyperspectral imaging technology combined with deep learning for hybrid okra seed identification

  2021cites this paper
• Environmental enrichment modulates silent information regulator 1 (SIRT1) activity to attenuate central presbycusis in a rat model of normal aging.

  2021cites this paper
• Potential of Red Okra Extract (Abelmoschus esculentus L. Moench) to Restore Kidney Damage due to Sodium Nitrite

  2021cites this paper
• Rutin prevents retinal ganglion cell death and exerts protective effects by regulating transforming growth factor-β2/Smad2/3Akt/PTEN signaling in experimental rat glaucoma

  2021cites this paper
• A review of the protective effects of quercetin-rich natural compounds for treating ischemia-reperfusion injury

  2021cites this paper
• Medicine and food with particular reference to chinpi, dried citrus peel, and a component of Ninjin'yoeito.

  2021cites this paper
• Rutin Attenuates Acrylamide Induced Neuropathic Pain via Inhibition of Proinflammatory Cytokines, Up-Regulation of Bcl-2 and Down-Regulation of Bax

  2021cites this paper
• Pharmacological properties of rutin and its potential uses for Alzheimer’s disease

  2021influential citation
• Effect of steam explosion on nutritional composition and antioxidative activities of okra seed and its application in gluten‐free cookies

  2020cites this paper
• Behavioral impairment and neurotoxic responses of silver catfish Rhamdia quelen exposed to organophosphate pesticide trichlorfon: Protective effects of diet containing rutin.

  2020cites this paper
• Assessment of growth and yield of okra (Abelmoschus esculentus) under surface and subsurface drip irrigation using treated waste water

  2020cites this paper
• Phenolic Compounds, Antioxidant Activities, and Inhibitory Effects on Digestive Enzymes of Different Cultivars of Okra (Abelmoschus esculentus)

  2020cites this paper
• Abelmoschus Esculentus (L.) Moench’s Peel Powder Improves High-Fat-Diet-Induced Cognitive Impairment in C57BL/6J Mice

  2020influential citation
• A review on the chemistry and biological properties of Rutin, a promising nutraceutical agent

  2019cites this paper
• The Neuroprotective Effect of Nasturtium officinale on Learning Ability and Density of Parvalbumin Neurons in the Hippocampus of Neurodegenerative- Induced Mice Model

  2019cites this paper
• The chemical and pharmacological basis of okra (Abelmoschus esculentus (L.) Moench) as potential therapy for type 2 diabetes

  2019cites this paper
• Natural products and their active principles used in the treatment of neurodegenerative diseases: a review

  2019cites this paper
• Utilization of Microfluidics for the Preparation of Polymeric Nanoparticles for the Antioxidant Rutin - a comparison with bulk production.

  2019cites this paper
• Potential Therapeutic Targets of Quercetin and Its Derivatives: Its Role in the Therapy of Cognitive Impairment

  2019cites this paper
• THE PROTECTIVE EFFECTS ABELMOSCHUS ESCULENTUS PODS SKIN AND SEEDS AGAINST NICOTINE INDUCED LIVER, KIDNEY DAMAGE IN MICE’

  2019cites this paper
• Placental Extract Improves Hippocampal Neuronal Loss and Fear Memory Impairment Resulting From Chronic Restraint Stress in Ovariectomized Mice

  2019cites this paper
• Investigation of the Effect of Quercetin on Neurological Alterations During Type 2 Diabetes Mellitus in Swiss Albino Mice

  2019cites this paper
• Quercetin promotes learning and memory performance concomitantly with neural stem/progenitor cell proliferation and neurogenesis in the adult rat dentate gyrus

  2019cites this paper
• Protection against Cholinesterase and Oxidative Stress Contributes to The Effect of Rutin ameliorating Ethanol-Induced Memory Dysfunction in Rats

  2019cites this paper
• Rutin as neuroprotective agent: from bench to bedside.

  2019cites this paper
• Rutin attenuates negatively charged surfactant (SDS)-induced lysozyme aggregation/amyloid formation and its cytotoxicity.

  2018cites this paper
• HPLC-DAD finger printing, antioxidant, cholinesterase, and α-glucosidase inhibitory potentials of a novel plant Olax nana

  2018cites this paper
• Quercetin protects against stress-induced anxiety- and depression-like behavior and improves memory in male mice.

  2018cites this paper
• Quercetin in Food: Possible Mechanisms of Its Effect on Memory.

  2018cites this paper
• Phytochemical information and pharmacological activities of Okra (Abelmoschus esculentus): A literature‐based review

  2018influential citation
• Health promoting properties of blueberries: a review

  2018cites this paper
• Ameliorative effects of rutin against cisplatin-induced reproductive toxicity in male rats

  2018cites this paper
• Protective effects of Abelmoschus moschatus seed extract on neurotransmitter system of developing brain of Wistar rats with gestational and post-natal exposure of sodium fluoride

  2018cites this paper
• Antidepressant activity of an aqueous extract from okra seeds

  2018cites this paper
• Extraction, characterisation and properties of polysaccharides from novel sources

  2018cites this paper
• Thermal degradation kinetics of rutin and total phenolic compounds in rosehip (Rosa canina L.) nectar Kuşburnu (Rosa canina L.) nektarında rutin ve toplam

  2018cites this paper
• Rutin alleviates chronic unpredictable stress-induced behavioral alterations and hippocampal damage in mice.

  2017cites this paper
• Okra ( Abelmoschus esculentus Linn) inhibits lipopolysaccharide-induced inflammatory mediators in BV2 microglial cells

  2017cites this paper
• Quercetin ameliorates chronic unpredicted stress-induced behavioral dysfunction in male Swiss albino mice by modulating hippocampal insulin signaling pathway.

  2017cites this paper
• A unique combination of micronutrients rejuvenates cognitive performance in aged mice

  2017cites this paper
• Preliminary Phyto-chemical screening of Abelmoschus esculentus Linn.

  2017cites this paper
• Determination of phenolic acids and rutin in Heliotropium thermophilum by high-performance liquid chromatography with photodiode array detection

  2017cites this paper
• Quercetin prevents chronic unpredictable stress induced behavioral dysfunction in mice by alleviating hippocampal oxidative and inflammatory stress.

  2017cites this paper
• Nootropic Medicinal Plants; Evaluating Potent Formulation By Novelestic High throughput Pharmacological Screening (HTPS) Method

  2017cites this paper
• Neuronal Cell Protective Effect of Dendropanax morbifera Extract against High Glucose-Induced Oxidative Stress

  2016cites this paper
• Metabolic Effects of Goutweed ( Aegopodium podagraria L.) Tincture and Metformin in Dexamethasone-Treated Rats

  2016cites this paper
• Target-guided isolation of polar antioxidants from Abelmoschus esculentus (L). Moench by high-speed counter-current chromatography method coupled with wavelength switching and extrusion elution mode.

  2016cites this paper
• Biochemical alterations of inflammatory markers in experimentally induced diabetes in rats

  2016cites this paper
• The Pharmacological Potential of Rutin

  2016cites this paper
• Rutin as a Natural Therapy for Alzheimer's Disease: Insights into its Mechanisms of Action.

  2016cites this paper
• Bioactive Compounds and Their Neuroprotective Effects in Diabetic Complications

  2016cites this paper
• Effects of quercetin on predator stress-related hematological and behavioural alterations in pregnant rats and their offspring

  2016cites this paper
• Attenuation of genotoxicity, oxidative stress, apoptosis and inflammation by rutin in benzo(a)pyrene exposed lungs of mice: plausible role of NF-κB, TNF-α and Bcl-2

  2016cites this paper
• Urtica dioica leaves modulates hippocampal smoothened-glioma associated oncogene-1 pathway and cognitive dysfunction in chronically stressed mice.

  2016cites this paper
• Myricetin protects hippocampal CA3 pyramidal neurons and improves learning and memory impairments in rats with Alzheimer's disease

  2016cites this paper
• Melatonin administration reverses the alteration of amyloid precursor protein-cleaving secretases expression in aged mouse hippocampus.

  2016cites this paper
• A chemical screen for medulloblastoma identifies quercetin as a putative radiosensitizer

  2016cites this paper
• Phytochemical and pharmacological investigations of Australian Acacia: An ethnomedicine-guided bioprospective approach

  2016cites this paper
• Chemical constitution and effect of extracts of tomato plants byproducts on the enteric viral surrogates

  2015cites this paper
• Screening of novel polyphyto formulations, a natural remedies for learning and memory enhancing properties in rat

  2015cites this paper
• Blanching alters the phenolic constituents and in vitro antioxidant and anticholinesterases properties of fireweed (Crassocephalum crepidioides)

  2015cites this paper
• Ultrasound-Assisted Extraction Process of Polysaccharides from Okra Assisted By Response Surface Methodology

  2015cites this paper
• Ameliorative effect of betulinic acid on oxidative damage and apoptosis in the splenocytes of dexamethasone treated mice.

  2015cites this paper
• The therapeutic potential of rutin for diabetes: an update.

  2015cites this paper
• The effects of okra (Abelmoschus esculentus Linn.) on the cellular events associated with Alzheimer's disease in a stably expressed HFE neuroblastoma SH-SY5Y cell line.

  2015cites this paper
• Antioxidant and Anti-Fatigue Constituents of Okra

  2015cites this paper
• Evaluation of spatial memory and locomotor activity during hypercortisolism induced by the administration of dexamethasone in adult male rats.

  2015cites this paper
• Quercetin protects human brain microvascular endothelial cells from fibrillar β-amyloid1–40-induced toxicity

  2015cites this paper
• Therapeutic effect of okra extract on gestational diabetes mellitus rats induced by streptozotocin.

  2015cites this paper