Lab-on-a-chip technologies for stem cell analysis.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Trends in Biotechnology

• Publication date

  2014-05-01

• Fields of study

  Biology, Medicine, Engineering

• Identifiers
  DOI 10.1016/j.tibtech.2014.03.004PMID 24726257
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Microfluidic Generation of Gradient Hydrogels to Modulate Hematopoietic Stem Cell Culture Environment

  2014cited by this paper
• Combined effects of flow-induced shear stress and micropatterned surface morphology on neuronal differentiation of human mesenchymal stem cells.

  2014cited by this paper
• New materials for microfluidics in biology.

  2014cited by this paper
• Advances in microfluidic materials, functions, integration, and applications.

  2013cited by this paper
• Impedance spectroscopy with field-effect transistor arrays for the analysis of anti-cancer drug action on individual cells.

  2013cited by this paper
• Capillary-valve-based platform towards cell-on-chip mechanotransduction assays

  2013cited by this paper
• One-step microfluidic generation of pre-hatching embryo-like core-shell microcapsules for miniaturized 3D culture of pluripotent stem cells.

  2013cited by this paper
• Carbon nanotube multi-electrode array chips for noninvasive real-time measurement of dopamine, action potentials, and postsynaptic potentials.

  2013cited by this paper
• Mechanically induced osteogenic lineage commitment of stem cells

  2013cited by this paper
• Organic ultra-thin film transistors with a liquid gate for extracellular stimulation and recording of electric activity of stem cell-derived neuronal networks.

  2013cited by this paper
• Microfluidic isolation of highly pure embryonic stem cells using feeder-separated co-culture system

  2013cited by this paper
• A novel microfluidic platform with stable concentration gradient for on chip cell culture and screening assays.

  2013cited by this paper
• Microfluidic systems: A new toolbox for pluripotent stem cells

  2013cited by this paper
• Enhancement of Renal Epithelial Cell Functions through Microfluidic-Based Coculture with Adipose-Derived Stem Cells

  2013cited by this paper
• From Cellular Cultures to Cellular Spheroids: Is Impedance Spectroscopy a Viable Tool for Monitoring Multicellular Spheroid (MCS) Drug Models?

  2013cited by this paper
• Exploitation of S-layer anisotropy: pH-dependent nanolayer orientation for cellular micropatterning.

  2013cited by this paper
• Microfluidic investigation of BDNF-enhanced neural stem cell chemotaxis in CXCL12 gradients.

  2013cited by this paper
• Genomagnetic assay for electrochemical detection of osteogenic differentiation in mesenchymal stem cells.

  2013cited by this paper
• Effects of Mechanical and Chemical Stimuli on Differentiation of Human Adipose-Derived Stem Cells into Endothelial Cells

  2013cited by this paper
• Development of a Multiplexed Microfluidic Platform for the Automated Cultivation of Embryonic Stem Cells

  2013cited by this paper
• Adult neural progenitor cells reactivate superbursting in mature neural networks.

  2012cited by this paper
• Microfluidic: an innovative tool for efficient cell sorting.

  2012cited by this paper
• Diffusion- and convection-based activation of Wnt/β-catenin signaling in a gradient generating microfluidic chip.

  2012cited by this paper
• Covalently immobilized biomolecule gradient on hydrogel surface using a gradient generating microfluidic device for a quantitative mesenchymal stem cell study.

  2012cited by this paper
• Magnetoresistive-based real-time cell phagocytosis monitoring.

  2012cited by this paper
• Laser-patterned stem-cell bridges in a cardiac muscle model for on-chip electrical conductivity analyses.

  2012cited by this paper
• Laser direct-write of single microbeads into spatially-ordered patterns

  2012cited by this paper
• Electric impedance sensing in cell-substrates for rapid and selective multipotential differentiation capacity monitoring of human mesenchymal stem cells.

  2012cited by this paper
• Adult neural progenitor cells reactivate superbursting in mature neural networks

  2012cited by this paper
• Atomic force microscopy reveals important differences in axonal resistance to injury.

  2012cited by this paper
• Microfluidics separation reveals the stem-cell–like deformability of tumor-initiating cells

  2012cited by this paper
• A microfluidic flow-stretch chip for investigating blood vessel biomechanics.

  2012cited by this paper
• Lithographic microfabrication of biocompatible polymers for tissue engineering and lab-on-a-chip applications

  2012cited by this paper
• Automated analysis of single stem cells in microfluidic traps.

  2012cited by this paper
• Multifrequency impedance measurement technique for wireless characterization of microbiological cell cultures.

  2011cited by this paper
• Graphene for controlled and accelerated osteogenic differentiation of human mesenchymal stem cells.

  2011cited by this paper
• Fluid shear stress primes mouse embryonic stem cells for differentiation in a self‐renewing environment via heparan sulfate proteoglycans transduction

  2011cited by this paper
• Microfluidic hydrogels for tissue engineering

  2011cited by this paper
• Development of a Surface Plasmon Resonance Biosensor for Real-Time Detection of Osteogenic Differentiation in Live Mesenchymal Stem Cells

  2011cited by this paper
• Mechanical stimulation of epithelial cells using polypyrrole microactuators.

  2011cited by this paper
• Stem cells in microfluidics.

  2011cited by this paper
• Microenvironment array chip for cell culture environment screening.

  2011cited by this paper
• Real-time label-free monitoring of adipose-derived stem cell differentiation with electric cell-substrate impedance sensing

  2011cited by this paper
• Artificial niche microarrays for probing single stem cell fate in high throughput

  2011cited by this paper
• Directed Stem Cell Differentiation by Fluid Mechanical Forces

  2011cited by this paper
• Enhanced cell sorting and manipulation with combined optical tweezer and microfluidic chip technologies.

  2011cited by this paper
• Mechanical stimulation of bovine embryos in a microfluidic culture platform

  2011cited by this paper
• Biophysical Characteristics Reveal Neural Stem Cell Differentiation Potential

  2011cited by this paper
• High-throughput combinatorial cell co-culture using microfluidics.

  2011cited by this paper
• Reconstituting Organ-Level Lung Functions on a Chip

  2010cited by this paper
• Extensive adipogenic and osteogenic differentiation of patterned human mesenchymal stem cells in a microfluidic device.

  2010cited by this paper
• Detection of the osteogenic differentiation of mesenchymal stem cells in 2D and 3D cultures by electrochemical impedance spectroscopy.

  2010cited by this paper
• Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells.

  2010cited by this paper
• Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of β-catenin signaling.

  2010cited by this paper
• Label-free cell separation and sorting in microfluidic systems

  2010cited by this paper
• High-performance single cell genetic analysis using microfluidic emulsion generator arrays.

  2010cited by this paper
• Gravitational field-flow fractionation of human hemopoietic stem cells.

  2009cited by this paper
• Microfluidic hydrodynamic cellular patterning for systematic formation of co-culture spheroids.

  2009cited by this paper
• Artificial Stem Cell Niches

  2009cited by this paper
• Response of mesenchymal stem cells to shear stress in tissue-engineered vascular grafts

  2009cited by this paper
• Microfluidic Control of Cell Pairing and Fusion

  2009cited by this paper
• Stem cells in microfluidics

  2009cited by this paper
• Can shear stress direct stem cell fate?

  2009cited by this paper
• An integrated microfluidic culture device for quantitative analysis of human embryonic stem cells.

  2009cited by this paper
• Simultaneous generation of chemical concentration and mechanical shear stress gradients using microfluidic osmotic flow comparable to interstitial flow.

  2009cited by this paper
• Unique Dielectric Properties Distinguish Stem Cells and Their Differentiated Progeny

  2008cited by this paper
• Effect of Intermittent Shear Stress on Mechanotransductive Signaling and Osteoblastic Differentiation of Bone Marrow Stromal Cells

  2008cited by this paper
• Regulatory Effects of Mechanical Strain on the Chondrogenic Differentiation of MSCs in a Collagen-GAG Scaffold: Experimental and Computational Analysis

  2008cited by this paper
• The response of human embryonic stem cell-derived endothelial cells to shear stress.

  2008cited by this paper
• A novel 3D mammalian cell perfusion-culture system in microfluidic channels.

  2007cited by this paper
• A chip-based platform for the in vitro generation of tissues in three-dimensional organization.

  2007cited by this paper
• Effects of shear stress on 3‐D human mesenchymal stem cell construct development in a perfusion bioreactor system: Experiments and hydrodynamic modeling

  2007cited by this paper
• Micromechanical control of cell–cell interactions

  2007cited by this paper
• The origins and the future of microfluidics

  2006cited by this paper
• Stem Cell Differentiation Base on Acoustic Wave Sensor

  2006cited by this paper
• In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation.

  2006cited by this paper
• Surface plasmon resonance imaging measurements of antibody arrays for the multiplexed detection of low molecular weight protein biomarkers.

  2006cited by this paper
• Matrix elasticity directs stem cell lineage specification.

  2006cited by this paper
• Oxygen in the Cultivation of Stem Cells

  2005cited by this paper
• Molded polyethylene glycol microstructures for capturing cells within microfluidic channels.

  2004cited by this paper
• Differential effects of equiaxial and uniaxial strain on mesenchymal stem cells

  2004cited by this paper
• Photopolymerization in Microfluidic Gradient Generators: Microscale Control of Substrate Compliance to Manipulate Cell Response

  2004cited by this paper
• Cyclic strain enhances matrix mineralization by adult human mesenchymal stem cells via the extracellular signal-regulated kinase (ERK1/2) signaling pathway.

  2003cited by this paper
• Adult stem cells for tissue repair - a new therapeutic concept?

  2003cited by this paper

• The Therapeutic Scope of Orofacial Mesenchymal Stem Cells

  2025cites this paper
• Recent Advances in Bone Tissue Engineering: Enhancing the Potential of Mesenchymal Stem Cells for Regenerative Therapies

  2025cites this paper
• Controllable Droplet Splitting with Parallel-Plate Optoelectrowetting Chips.

  2025cites this paper
• Study on droplet splitting in single-plate OEW chips

  2025cites this paper
• Optimising Bioprinting Nozzles through Computational Modelling and Design of Experiments

  2024cites this paper
• Chromatin remodeling in tissue stem cell fate determination

  2024cites this paper
• Revolutionizing healthcare: Emerging frontiers in 3D bioprinting of tissues and organs

  2024cites this paper
• Advances in biomedical fluid–structure interaction: Methodologies and applications from an interfacing perspective

  2024cites this paper
• Recent Advances of Biosensor-Integrated Organ-on-a-Chip Technologies for Diagnostics and Therapeutics.

  2023cites this paper
• Optimal experimental design for efficient toxicity testing in microphysiological systems: A bone marrow application

  2023cites this paper
• Characterization of Benchtop-Fabricated Arrays of Nanowrinkled Surface Electrodes as a Nitric Oxide Electrochemical Sensor

  2023cites this paper
• Culturing cells for life: innovative approaches in macroscopic and microfluidic cultures, with an emphasis on stem cells

  2023cites this paper
• Hydrophilic Modification Strategies to Enhance the Surface Biocompatibility of Poly(dimethylsiloxane)‐Based Biomaterials for Medical Applications

  2023cites this paper
• Advances in non-invasive biosensing measures to monitor wound healing progression

  2022cites this paper
• Direct 3D printed biocompatible microfluidics: assessment of human mesenchymal stem cell differentiation and cytotoxic drug screening in a dynamic culture system

  2022cites this paper
• Low-Cost Devices for Three-Dimensional Cell Aggregation, Real-Time Monitoring Microscopy, Microfluidic Immunostaining, and Deconvolution Analysis

  2022cites this paper
• Organ-on-a-Chip: Design and Simulation of Various Microfluidic Channel Geometries for the Influence of Fluid Dynamic Parameters

  2022cites this paper
• Optimization of a PDMS-Based Cell Culture Substrate for High-Density Human-Induced Pluripotent Stem Cell Adhesion and Long-Term Differentiation into Cardiomyocytes under a Xeno-Free Condition.

  2022cites this paper
• Micro-tweezers and Force Microscopy Techniques for Single-Cell Mechanobiological Analysis

  2021cites this paper
• A Decade of Organs-on-a-Chip Emulating Human Physiology at the Microscale: A Critical Status Report on Progress in Toxicology and Pharmacology

  2021cites this paper
• Methods of Generating Dielectrophoretic Force for Microfluidic Manipulation of Bioparticles.

  2021cites this paper
• Testing Lab-on-a-Chip Technology for Culturing Human Melanoma Cells under Simulated Microgravity

  2021cites this paper
• Microfluidics: a review

  2021cites this paper
• Microfluidics-Based Single-Cell Research for Intercellular Interaction

  2021cites this paper
• New Endeavors of (Micro)Tissue Engineering: Cells Tissues Organs on-Chip and Communication Thereof

  2021cites this paper
• Cell Culture Conditions: Cultivation of Stem Cells Under Dynamic Conditions

  2020cites this paper
• Interdigitated aluminium and titanium sensors for assessing epithelial barrier functionality by electric cell-substrate impedance spectroscopy (ECIS)

  2020cites this paper
• PDMS Nano-Modified Scaffolds for Improvement of Stem Cells Proliferation and Differentiation in Microfluidic Platform

  2020cites this paper
• Biocompatible PEGDA Resin for 3D Printing.

  2020cites this paper
• Advances in numerical approaches for microfluidic cell analysis platforms

  2020cites this paper
• An overview of extrusion-based bioprinting with a focus on induced shear stress and its effect on cell viability

  2020cites this paper
• Biosensors in Animal Biotechnology

  2019cites this paper
• Chapter 2 Recent Development of Cell Analysis on Micro fl udics

  2019cites this paper
• Characterization of four functional biocompatible pressure-sensitive adhesives for rapid prototyping of cell-based lab-on-a-chip and organ-on-a-chip systems

  2019cites this paper
• Integrating Organs-on-Chips: Multiplexing, Scaling, Vascularization, and Innervation.

  2019cites this paper
• Development of a Novel Bioprinting System:Bioprinter, Bioink, Characterizationand Optimization

  2019cites this paper
• Rapid and Highly Controlled Generation of Monodisperse Multiple Emulsions via a One-Step Hybrid Microfluidic Device

  2019cites this paper
• Recent progresses in graphene based bio-functional nanostructures for advanced biological and cellular interfaces

  2019cites this paper
• Autologous induced pluripotent stem cell-derived four-organ-chip

  2019cites this paper
• Latest Trends in Biosensing for Microphysiological Organs-on-a-Chip and Body-on-a-Chip Systems

  2019cites this paper
• Gold Nanowires/Fibrin Nanostructure as Microfluidics Platforms for Enhancing Stem Cell Differentiation: Bio-AFM Study

  2019cites this paper
• Microfluidic devices, accumulation of endogenous signals and stem cell fate selection.

  2019cites this paper
• Rapid and Robust Coating Method to Render Polydimethylsiloxane Surfaces Cell Adhesive.

  2019cites this paper
• Microfluidic three-dimensional cell culture of stem cells for high-throughput analysis

  2019cites this paper
• Introduction

  2019cites this paper
• Progress, obstacles, and limitations in the use of stem cells in organ-on-a-chip models.

  2019cites this paper
• Tomorrow today: organ-on-a-chip advances towards clinically relevant pharmaceutical and medical in vitro models.

  2019cites this paper
• Long-Term Perfusion Culture of Monoclonal Embryonic Stem Cells in 3D Hydrogel Beads for Continuous Optical Analysis of Differentiation.

  2019cites this paper
• Innovative Approaches for Pre-Screening and Sensing of Diseases

  2019cites this paper
• The Third Dimension in Cell Culture: From 2D to 3D Culture Formats

  2018cites this paper
• Towards an autologous iPSC-derived patient-on-a-chip

  2018cites this paper
• Microsystems for electromechanical stimulations to engineered cardiac tissues

  2018cites this paper
• Cardiac Cell Culture Microtechnologies Based on Stem Cells

  2018cites this paper
• Engineering Tools to Further Neuroscientific Investigation

  2018cites this paper
• Recent Development of Cell Analysis on Microfludics

  2018cites this paper
• Towards Low-Cost Cell Culturing Platforms with Integrated Sensing Capabilities

  2018cites this paper
• Every Breath You Take: Non-invasive Real-Time Oxygen Biosensing in Two- and Three-Dimensional Microfluidic Cell Models

  2018cites this paper
• One-step synthesis of bifunctional PEGDA/TiO 2 composite film by photopolymerization for the removal of Congo red

  2018cites this paper
• Stem Cell-Based Therapies for Polyglutamine Diseases.

  2018cites this paper
• Next-Generation Live-Cell Microarray Technologies.

  2018cites this paper
• Impedance-based real-time position sensor for lab-on-a-chip devices.

  2018cites this paper
• Combinatorial in Vitro and in Silico Approach To Describe Shear-Force Dependent Uptake of Nanoparticles in Microfluidic Vascular Models.

  2018cites this paper
• Subtractive Manufacturing of Microfluidic 3D Braid Mixers

  2018cites this paper
• Functional Graphene Nanomaterials Based Architectures: Biointeractions, Fabrications, and Emerging Biological Applications.

  2017cites this paper
• Label‐Free and Regenerative Electrochemical Microfluidic Biosensors for Continual Monitoring of Cell Secretomes

  2017cites this paper
• Combined effects of multi-scale topographical cues on stable cell sheet formation and differentiation of mesenchymal stem cells.

  2017cites this paper
• Microfabricated tools for quantitative plant biology.

  2017cites this paper
• A microfluidic module for real-time generation of complex multi-molecule temporal concentration profiles

  2017cites this paper
• Stem cell culture and differentiation in microfluidic devices toward organ-on-a-chip

  2017cites this paper
• Recent lab‐on‐chip developments for novel drug discovery

  2017cites this paper
• Application of Bioreactor in Stem Cell Culture

  2017cites this paper
• Label-free microfluidic stem cell isolation technologies

  2017cites this paper
• Pluripotent Stem Cells and Skeletal Muscle Differentiation: Challenges and Immediate Applications

  2017cites this paper
• Materials and methods of signal enhancement for spectroscopic whole blood analysis: Novel research overview

  2017cites this paper
• Sample pre-treatment techniques for use with ICP-MS hyphenated techniques for elemental speciation in biological samples

  2017cites this paper
• Delivery of Amphotericin B to Candida albicans by Using Biomachined Lab-on-a-Chip

  2017cites this paper
• Simple potential bioanalysis micro reactor fabricated by vertically-aligned multi-walled carbon nanotubes (MWCNTS)

  2017cites this paper
• In situ generation of human brain organoids on a micropillar array.

  2017cites this paper
• Microfluidic Migration and Wound Healing Assay Based on Mechanically Induced Injuries of Defined and Highly Reproducible Areas.

  2017cites this paper
• Accelerating practical applications of cutting edge human iPS cell technologies.

  2017cites this paper
• Recombinant drugs-on-a-chip: The usage of capillary electrophoresis and trends in miniaturized systems - A review.

  2016cites this paper
• Microfluidic platform for photodynamic therapy cytotoxicity analysis of nanoencapsulated indocyanine-type photosensitizers.

  2016cites this paper
• THE ROLE OF LAB-ON-A-CHIP DEVICE IN HEALTH CARE

  2016cites this paper
• Microfluidic Devices for the Culture of Stem Cells

  2016cites this paper
• Biochemical analysis on microfluidic chips

  2016cites this paper
• Theoretical modeling in microscale locomotion

  2016cites this paper
• Biomaterial-Based Microfluidics for Cell Culture and Analysis

  2016cites this paper
• Exploiting the Potential of OLED-Based Photo-Organic Sensors forBiotechnological Applications

  2016cites this paper
• On the Use of Scalable NanoISFET Arrays of Silicon with Highly Reproducible Sensor Performance for Biosensor Applications

  2016cites this paper
• Cell Microarrays for Biomedical Applications.

  2016cites this paper
• Heart-on-a-chip based on stem cell biology.

  2016cites this paper
• Regulation of mesenchymal stem cell 3D microenvironment: From macro to microfluidic bioreactors

  2016cites this paper
• Theoretical modeling in microscale locomotion

  2016cites this paper
• Hybrid hydrogel-aligned carbon nanotube scaffolds to enhance cardiac differentiation of embryoid bodies.

  2016cites this paper
• Characterization of Phenotypic and Transcriptional Differences in Human Pluripotent Stem Cells under 2D and 3D Culture Conditions

  2016cites this paper
• Data Processing in Cellular Microphysiometry

  2016cites this paper
• Real‐time monitoring of specific oxygen uptake rates of embryonic stem cells in a microfluidic cell culture device

  2016cites this paper
• Developments in 3D neural cell culture models: the future of neurotherapeutics testing?

  2016cites this paper
• Microfluidic co-culture platform to quantify chemotaxis of primary stem cells.

  2016cites this paper
• Delivery of minimally dispersed liquid interfaces for sequential surface chemistry.

  2016cites this paper