Potentiation of cyclosporine by verapamil in vitro.

No abstract is available for this paper.

• Publication year

  1985

• Venue

  Transplantation

• Publication date

  1985-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/00007890-198510000-00021PMID 4049498
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Verapamil inhibition of lymphocyte proliferation and function in vitro.

  1985cited by this paper
• Cyclosporine.

  1984cited by this paper
• Cyclophilin: a specific cytosolic binding protein for cyclosporin A.

  1984cited by this paper
• Cyclosporine-associated chronic nephropathy.

  1984cited by this paper
• The interference of T cell activation by calcium channel blocking agents.

  1984cited by this paper
• The role of calmodulin in the regulation of human lymphocyte activation.

  1984cited by this paper
• Free cytoplasmic calcium concentration and the mitogenic stimulation of lymphocytes.

  1983cited by this paper
• Promotion by verapamil of vincristine responsiveness in tumor cell lines inherently resistant to the drug.

  1983cited by this paper
• The role of calcium in lymphocyte proliferation. (An interpretive review).

  1983cited by this paper
• Calcium antagonists and calmodulin: effect of verapamil, nifedipine and diltiazem.

  1983cited by this paper
• Evidence for an interleukin-independent pathway for human lymphocyte activation.

  1983cited by this paper
• Permissive role of calcium in the inhibition of T cell mitogenesis by calmodulin antagonists.

  1983cited by this paper
• The cellular target of cyclosporin A action in humans.

  1982cited by this paper
• Mechanism of action of calcium-channel-blocking agents.

  1982cited by this paper
• Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2

  1981cited by this paper
• Calmodulin—an intracellular calcium receptor

  1980cited by this paper
• Calmodulin plays a pivotal role in cellular regulation.

  1980cited by this paper
• The role of calcium ions in the regulation of rat thymocyte pyruvate oxidation by mitogens.

  1978cited by this paper
• Calcium and lymphocyte activation.

  1976cited by this paper

• Core Concepts in Hypertension in Kidney Disease

  2016cites this paper
• Drug-Induced Hypertension in Chronic Kidney Disease

  2016cites this paper
• In vitro analysis of verapamil-induced immunosuppression: potent inhibition of T cell motility and lymphocytic transmigration through allogeneic endothelial cells.

  2000cites this paper
• The Clinical and Economic Potential of Cyclosporin Drug Interactions

  1999cites this paper
• P‐glycoprotein and Drug Therapy in Organ Transplantation

  1999cites this paper
• Novel mode of action of the calcium antagonist mibefradil (Ro 40‐5967): potent immunosuppression by inhibition of T‐cell infiltration through allogeneic endothelium

  1998cites this paper
• Calcium channel blockers suppress the contact hypersensitivity reaction (CHR) by inhibiting antigen transport and presentation by epidermal Langerhans cells in mice

  1997cites this paper
• Accelerated arteriosclerosis after transplantation: the possible role of calcium channel blockers.

  1997cites this paper
• The modulatory effect of diltiazem on human in vitro alloreactivity when used alone or in combination with cyclosporin A and/or methylprednisolone

  1997cites this paper
• Renal haemodynamic and protective effects of calcium antagonists in hypertension.

  1995cites this paper
• Effect of calcium-channel blocker on tumour necrosis factor alpha (TNF alpha) production in cyclosporin-treated renal transplant recipients.

  1995cites this paper
• MDR1 gene expression in lymphocytes of patients with renal transplants.

  1995cites this paper
• Immunosuppressive effects of different calcium channel blockers in human kidney allografts.

  1995cites this paper
• A PRELIMINARY REPORT OF DILTIAZEM AND KETOCONAZOLE: THEIR CYCLOSPORINE‐SPARING EFFECT AND IMPACT ON TRANSPLANT OUTCOME1

  1994cites this paper
• Modulation of adhesion molecule expression on endothelial cells by verapamil and other Ca++ channel blockers.

  1994cites this paper
• [Value of a powerful initial immunosuppression after liver transplantation. Prospective study of 60 cases].

  1994cites this paper
• Immunosuppressive Properties of Calcium Channel Blockers

  1993cites this paper
• A controlled, double-blind, randomized trial of verapamil and cyclosporine in cadaver renal transplant patients.

  1993cites this paper
• Converting-enzyme inhibitor versus calcium antagonist in cyclosporine-treated renal transplants.

  1993cites this paper
• Cyclosporin metabolism in transplant patients.

  1993cites this paper
• Calcium antagonists prevent cyclosporin a-Induced nephrotoxicity

  1993cites this paper
• Effects of the calcium channel blocker diltiazem on cyclosporin nephrotoxicity in renal transplant patients

  1992cites this paper
• Lack of effect of isradipine on cyclosporin pharmacokinetics

  1992cites this paper
• Diltiazem co-administration reduces cyclosporine toxicity after heart transplantation: a prospective randomised study.

  1992cites this paper
• Additive inhibition of afferent and efferent immunological responses of human peripheral blood mononuclear cells by verapamil and cyclosporine.

  1991cites this paper
• [Drug interactions of cyclosporine. Literature review].

  1991cites this paper
• Pharmacokinetic determinants of cyclosporine and prednisone in renal transplant patients.

  1991cites this paper
• Verapamil improves the outcome after cadaver renal transplantation.

  1991cites this paper
• Effect of calcium-channel blockers on renal function in renal-graft recipients treated with cyclosporine.

  1991cites this paper
• IMPROVED OUTCOME OF CADAVERIC RENAL TRANSPLANTATION DUE TO CALCIUM CHANNEL BLOCKERS

  1991cites this paper
• Management of Drug Interactions With Cyclosporine

  1991cites this paper
• Therapeutic benefits of calcium channel blockers in cyclosporine-treated organ transplant recipients: blood pressure control and immunosuppression.

  1991cites this paper
• Acute inhibition of human renal tubular cell growth by cyclosporin A.

  1990cites this paper
• The potential of cyclosporin A as an anti-tumour agent.

  1990cites this paper
• Modulation of murine in vitro immune response by verapamil (V).

  1990cites this paper
• Calcium channel blockers in organ transplantation: important new therapeutic modalities.

  1990cites this paper
• Additive effects of calcium antagonists on cyclosporin A-induced inhibition of T-cell proliferation.

  1990influential citation
• Verapamil prevents posttransplant delayed function and cyclosporine A nephrotoxicity.

  1990cites this paper
• Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.

  1990cites this paper
• Do calcium channel blockers have any influence on the immunological status of renal graft recipients on ciclosporin therapy?

  1990cites this paper
• The additive effect of certain drugs on the Cyclosporine A inhibition of human T‐cell proliferation

  1990cites this paper
• Calcium-channel blockers and other factors influencing delayed function in renal allografts.

  1990cites this paper
• The influence of cyclosporin A on T cell activation, cytokine gene expression and cell-mediated immunity

  1989cites this paper
• The effect of calcium channel blocking on immune capacity of cardiovascular patients.

  1989cites this paper
• Prevention of acute cyclosporine-induced renal blood flow inhibition and improved immunosuppression with verapamil.

  1989cites this paper
• An appraisal of drug interactions with Sandimmun.

  1989cites this paper
• Verapamil ameliorates acute cyclosporine A (CsA) nephrotoxicity and improves immunosuppression after cadaver renal transplantation.

  1989cites this paper
• Potentiation of immunosuppressive effects of cyclosporin A by 1 alpha,25-dihydroxyvitamin D3.

  1989cites this paper
• Additive inhibitory effect of cyclosporine and verapamil may occur through different mechanisms that may be dependent or independent of the slow calcium channel.

  1989cites this paper
• Cyclosporin A nephrotoxicity.

  1989cites this paper
• Clinical pharmacokinetics of cyclosporin.

  1989cites this paper
• The effect of nifedipine on graft function in renal allograft recipients treated with cyclosporin A.

  1989cites this paper
• Use of verapamil with conventional immunosuppression after porcine renal transplantation.

  1989cites this paper
• Sandimmun®/An Appraisal of Drug Interactions

  1989cites this paper
• Potentiation of immunosuppressive effects of cyclosporin A by 1α,25-dihydroxyvitamin D3

  1989cites this paper
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  1988cites this paper
• Nicardipine enhances the effect of cyclosporine A on T lymphocyte activation in vitro.

  1988cites this paper
• The influence of antihypertensive drug therapy on renal transplant function and outcome.

  1988cites this paper
• Pharmacologic and immunologic agonists and antagonists of cyclosporine.

  1988cites this paper
• In vivo fluorescence microscopy of kidney subcapsular blood flow in mice. Effects of cyclosporine, (NVA2)-cyclosporine, and isradipine, a new calcium antagonist.

  1988cites this paper
• Additive effect of cyclosporine and verapamil on the inhibition of activation and function of human peripheral blood mononuclear cells.

  1988cites this paper
• THE EFFECT OF VERAPAMIL ON CELLULAR UPTAKE, ORGAN DISTRIBUTION, AND PHARMACOLOGY OF CYCLOSPORINE

  1987cites this paper
• Low-dose azathioprine is synergistic with low-dose cyclosporine in rabbit skin allograft survival.

  1987cites this paper
• INDUCTION OF CONTRACTION IN ISOLATED RAT AORTA BY CYCLOSPORINE

  1987cites this paper
• In vivo potentiation of cyclosporine immunosuppression by calcium antagonists.

  1987cites this paper
• Cyclosporine Drug Interactions: A Review

  1987cites this paper
• Cyclosporine A: a clinical evaluation of drug interactions.

  1986cites this paper