Factors affecting the diurnal variation in the level of -hydroxy- -methylglutaryl coenzyme A reductase and cholesterol-synthesizing activity in rat liver.

No abstract is available for this paper.

• Publication year

  1972

• Venue

  Archives of Biochemistry and Biophysics

• Publication date

  1972-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0003-9861(72)90188-9PMID 5072698
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The effects of fasting, refeeding, and time of day on the levels of enzymes effecting the conversion of -hydroxy- -methylglutaryl-coenzyme A to squalene.

  1972cited by this paper
• Effect of adrenalectomy on the diurnal variation of hepatic cholesterogenesis in the rat.

  1972cited by this paper
• The mechanism of the diurnal variation of hepatic HMG-CoA reductase activity in the rat.

  1971cited by this paper
• Stereospecificity of the transfer of hydrogen from reduced nicotinamide adenine dinucleotide phosphate in each of the two reductive steps catalyzed by beta-hydroxy-beta-methylglutaryl coenzyme A reductase.

  1971cited by this paper
• Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol synthesis.

  1971cited by this paper
• Regulation of 3-hydroxy-3-methylglutarate and mevalonate biosynthesis by rat liver homogenates. Effects of fasting, cholesterol feeding, and triton administration.

  1970cited by this paper
• Control of enzyme levels in animal tissues.

  1970cited by this paper
• Diurnal incorporation of 3H‐leucine into liver protein

  1970cited by this paper
• Prevention of cyclic and triton-induced increases in hydroxymethylglutaryl coenzyme A reductase and sterol synthesis by puromycin.

  1969cited by this paper
• Hepatic tyrosine transaminase rhythm: interaction of environmental lighting, food consumption and dietary protein content.

  1969cited by this paper
• Diurnal variation and cholesterol regulation of hepatic HMG-CoA reductase activity.

  1969cited by this paper
• Rhythmic changes of hydroxymethylglutaryl coenzyme a reductase activity in livers of fed and fasted rats

  1969cited by this paper
• Regulation of cholesterol biosynthesis in rat liver: diurnal changes of activity and influence of bile acids.

  1969cited by this paper
• Thin-layer chromatographic assay for HMG-CoA reductase and mevalonic acid.

  1969cited by this paper
• Circadian Oscillation in Rat Liver Tryptophan Pyrrolase and its Analysis by Substrate and Hormone Induction

  1968cited by this paper
• Feeding Schedule Alteration of Daily Rhythm in Tyrosine Alpha-Ketoglutarate Transaminase of Rat Liver

  1968cited by this paper
• Feedback control of mevalonate synthesis by dietary cholesterol.

  1966cited by this paper
• The biosynthesis of cholesterol from acetate-1-C14 by cellular fractions of rat liver.

  1956cited by this paper

• Non-linear relationship between the first meal time of the day and gallstone incidence in American adults: a population-based cross-sectional study

  2024cites this paper
• Caloric Restriction and Bile Salt Dynamics in Intact and Cholecystectomized Syrian Hamsterst

  2019cites this paper
• Copyright: Second Edition

  2013cites this paper
• (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1h-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): a rationally designed orally efficacious 3-hydroxy-3-methylglutaryl coenzyme-a reductase inhibitor with reduced myotoxicity potential.

  2008cites this paper
• Daily rhythms of serum lipids in dogs: influences of lighting and fasting cycles.

  2008cites this paper
• Diurnal variation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in latex ofHevea brasiliensis and its relation to rubber content

  2005cites this paper
• Daily oscillations in liver function: diurnal vs circadian rhythmicity

  2004cites this paper
• Induction of fatty acid synthetase and acetyl-CoA carboxylase by isolated rat liver cells

  2004cites this paper
• Circadian rhythms of body temperature and liver function in fed and food-deprived goats.

  2003cites this paper
• Regulation of cholesterol biosynthesis by diet in humans.

  1997cites this paper
• 7 alpha-hydroxylation of 27-hydroxycholesterol: biologic role in the regulation of cholesterol synthesis.

  1997cites this paper
• The diurnal variation of hepatic HMG-CoA reductase activity is due to changes in the level of immunoreactive protein.

  1996cites this paper
• Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver.

  1996cites this paper
• Cholesterol Homeostasis: Role of the LDL Receptor

  1995cites this paper
• Regulatory enzymes of lipid metabolism in LA/N-cp rats.

  1995cites this paper
• In vivo requirement of protein prenylation for maintenance of retinal cytoarchitecture and photoreceptor structure

  1995cites this paper
• Effect of meal timing on diurnal rhythm of human cholesterol synthesis.

  1995cites this paper
• Entrainment of circadian rhythms of cholesterol‐LDL, corticosterone and motor activity by feeding schedules in rats

  1994cites this paper
• Insulin and glucagon modulate hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity by affecting immunoreactive protein levels.

  1994cites this paper
• Diurnal variations in the plasma concentrations of mevalonic acid in patients with abetalipoproteinaemia

  1994cites this paper
• Meal-frequency effects on plasma hormone concentrations and cholesterol synthesis in humans.

  1993cites this paper
• Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo.

  1993cites this paper
• RG 12561 (dalvastatin): a novel synthetic inhibitor of HMG-CoA reductase and cholesterol-lowering agent.

  1993cites this paper
• Nutrient intake as a time signal for circadian rhythm.

  1992cites this paper
• The effect of a histidine-excess diet on cholesterol synthesis and degradation in rats

  1992cites this paper
• Inhibition of cholesterol synthesis in vitro by extracts and isolated compounds prepared from garlic and wild garlic.

  1992cites this paper
• Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety.

  1991cites this paper
• Use of deuterated water for measurement of short-term cholesterol synthesis in humans.

  1990cites this paper
• Effects of the hypocholesterolemic compound K12.148 on serum lipids and parameters of clinical chemistry of pigs

  1990cites this paper
• Evidence for diurnal periodicity in human cholesterol synthesis.

  1990cites this paper
• Critical analysis of the use of 14C-acetate for measuring in vivo rat cholesterol synthesis.

  1990cites this paper
• Hep-G2 cells and primary rat hepatocytes differ in their response to inhibitors of HMG-CoA reductase.

  1990cites this paper
• Inhibitors of cholesterol biosynthesis. 1. trans-6-(2-pyrrol-1-ylethyl)-4-hydroxypyran-2-ones, a novel series of HMG-CoA reductase inhibitors. 1. Effects of structural modifications at the 2- and 5-positions of the pyrrole nucleus.

  1990cites this paper
• Hypolipemic activity of K12.148 in rats, marmosets and pigs.

  1989cites this paper
• Effect of human apolipoprotein E phenotype on endogenous cholesterol synthesis as measured by deuterium in corporation

  1988cites this paper
• Regulation of hepatic cholesterogenesis by polar steroids accumulated after cholesterol feeding

  1988cites this paper
• Modulation of the enzymic activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase by multiple kinase systems involving reversible phosphorylation: a review.

  1987cites this paper
• Diurnal variation in hepatic expression of the rat S14 gene is synchronized by the photoperiod.

  1987cites this paper
• Circadian variation of the hypocholesterolemic effect of K13.004 in rats.

  1987cites this paper
• Short-Term changes in hepatic HMG-CoA reductase in rats fed diets containing cholesterol or oat bran

  1987cites this paper
• Feeding-Induced Regulation of Cholesterol Metabolism: A Unified Proposal

  1986influential citation
• Cyclohexanol and methylcyclohexanols. A family of inhibitors of hepatic HMGCoA reductase in vivo.

  1986cites this paper
• Regulation of cholesterol biosynthesis.

  1986cites this paper
• Diurnal variation in the fraction of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the active form in the mammary gland of the lactating rat.

  1986cites this paper
• Chapter 2 Control mechanisms in sterol uptake and biosynthesis

  1985cites this paper
• Cholesterol metabolism: use of D2O for determination of synthesis rate in cell culture.

  1985cites this paper
• 3 – Reversible Phosphorylation of Hepatic HMG-CoA Reductase in Endocrine and Feedback Control of Cholesterol Biosynthesis

  1985cites this paper
• Circadian rhythm of HMG-CoA reductase and insulin in African green monkeys.

  1985cites this paper
• Diurnal changes in the rate of cholesterogenesis in hepatocytes from fed and starved rats: effects of precursors and pancreatic hormones in vitro.

  1985cites this paper
• Diurnal changes in the fraction of 3-hydroxy-3-methylglutaryl-CoA reductase in the active form in rat liver microsomal fractions.

  1984cites this paper
• 3-Hydroxy-3-methyl-glutaryl coenzyme A reductase activity in chicks fed coumestrol, a phytoestrogen.

  1984cites this paper
• Diurnal variation of plasma methyl sterols and cholesterol in the rat: Relation to hepatic cholesterol synthesis

  1984cites this paper
• In vivo inhibition of hepatic lipogenesis in the rat by cyclandelate (3,3',5-trimethylcyclohexanylmandelate).

  1983cites this paper
• Effect of removal of lipoproteins of different composition on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and hepatic very low density lipoprotein secretion.

  1983cites this paper
• Regulation of short-term changes in hepatic beta-hydroxy-beta-methylglutaryl-CoA reductase activity.

  1982cites this paper
• Development of the diurnal rhythm of chick 3-hydroxy-3-methylglutaryl-CoA reductase

  1982cites this paper
• Mode of action of terbufibrol (INN) a hypolipidemic agent on rat liver sterol synthesis.

  1982cites this paper
• Influence of the light regimen on the circadian rhythm of serum lipids in the laboratory rat.

  1982cites this paper
• Regulation of Short‐Term Changes in Hepatic β‐Hydroxy‐β‐methylglutaryl‐CoA Reductase Activity

  1982cites this paper
• Rat Brain 3‐Hydroxy‐3‐Methylglutaryl‐CoA Reductase: Subcellular Distribution and Cold Lability

  1981cites this paper
• Hepatic cholesterogenesis in Chileans with cholesterol gallstone disease. Evidence for sex differences in the regulation of hepatic cholesterol metabolism.

  1981cites this paper
• Hepatic cholesterogenesis in Chileans with cholesterol gallstone disease. Evidence for sex differences in the regulation of hepatic cholesterol metabolism

  1981cites this paper
• Coordinate regulation of cholesterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A synthase but not 3-hydroxy-3-methylglutaryl coenzyme A reductase in C-6 glia.

  1981cites this paper
• Membrane cholesterol, tumorigenesis, and the biochemical phenotype of neoplasia.

  1981cites this paper
• Measurement of hepatic sterol synthesis in the Mongolian gerbil in vivo using [3H]water: diurnal variation and effect of type of dietary fat.

  1981cites this paper
• Circadian variation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in swine liver and ileum.

  1981cites this paper
• Hepatic microsomal 3-hydroxy-3-methylglutaryl-CoA reductase activity in the lactating rat.

  1981cites this paper
• Immunotitration of 3-hydroxy-3-methylglutaryl-CoA reductase.

  1981cites this paper
• Effects of sphincter of Oddi bypass on bile acid metabolism in fed and fasted intact and cholecystectomized dogs.

  1981cites this paper
• Cytosolic proteins that bind oxygenated sterols. Cellular distribution, specificity, and some properties.

  1980cites this paper
• Effects of fasting on the composition of gallbladder bile.

  1980cites this paper
• Inhibition of hepatic cholesterol synthesis and S-3-hydroxy-3-methylglutaryl-CoA reductase by mono and bicyclic monoterpenes administered in vivo.

  1980cites this paper
• Activation and inactivation of 3-hydroxy-3-methylglutaryl coenzyme a reductase in aged rat liver.

  1980cites this paper
• Studies on the mechanisms of the rapid modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in intact liver by mevalonolactone and 25-hydroxycholesterol.

  1980cites this paper
• Relationships between cholesterogenesis, microsomal sterols and HMG-CoA reductase in the perfused rat liver

  1980cites this paper
• In vivo and in vitro mechanisms regulating rat liver beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity.

  1980cites this paper
• Changes in sterol biosynthesis accompanying cessation of glial cell growth in serum-free medium.

  1980cites this paper
• Food availability and daily biological rhythms.

  1980cites this paper
• Short-term Hormonal Control of Hepatic Lipogenesis

  1980cites this paper
• Diurnal variations in the activity of enzymes regulating lipid metabolism and in tissue lipid levels of adult rats fed different fat sources and cholesterol

  1979cites this paper
• Elevation of HeLa cell 3‐hydroxy‐3‐methylglutaryl coenzyme a reductase activity by glucocorticoids: Possible relationship to the cell cycle

  1979cites this paper
• Comparative effects of purified and human-type diets on cholesterol metabolism in the rat.

  1979cites this paper
• Utilization of endogenous and exogenous sources of substrate for cholesterol biosynthesis by isolated hepatocytes.

  1979cites this paper
• Immunotitration of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in various physiological states.

  1979cites this paper
• An alternate method of purification and properties of rat liver beta-hydroxy-beta-methylglutaryl coenzyme A reductase.

  1979cites this paper
• L-Histidine-Induced Facilitation of Cholesterol Biosynthesis in Rats 1

  1978cites this paper
• Effects of 25-hydroxycholesterol on rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in vivo, in perfused liver, and in hepatocytes.

  1978cites this paper
• Coordinate repression of cholesterol biosynthesis and cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase by glucocorticoids in HeLa cells.

  1978cites this paper
• Reversible modulation of liver hydroxymethylglutaryl CoA reductase.

  1978cites this paper
• Impairment of hepatic cholesterol synthesis from squalene and the function of hepatic sterol carrier protein system by ageing.

  1978cites this paper
• Regulation of cholesterol biosynthesis in HeLa S3G cells by serum lipoproteins: dexamethasone-mediated interference with suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

  1978cites this paper
• CHAPTER 4 – Hormonal Regulation of Cholesterol Synthesis

  1977cites this paper
• Hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity in hamsters on a lithogenic diet.

  1977cites this paper
• Short- and long-term effects of ethanol administration in vivo on rat liver HMG-CoA reductase and cholesterol 7alpha-hydroxylase activities.

  1977cites this paper
• Control of 3-hydroxy-3-methylglutaryl coenzyme A reductase by endogenously synthesized sterols in vitro and in vivo.

  1977cites this paper
• Significance of rare mRNA sequences in liver

  1977cites this paper
• Dog liver 3-hydroxy-3-methylglutaryl coenzyme A reductase.

  1977cites this paper
• Significance of rare m RNA sequences in liver.

  1977cites this paper
• Thiobarbituric acid reactive substances (TBARS) and lipid metabolism in α-tocopherol deficient rats

  1977cites this paper
• Persistence of dietary suppression of 3-hydroxy-3-methylglutaryl coenzyme-A reductase during development in rats.

  1977cites this paper