Phosphorylation‐dependent and constitutive activation of Rho proteins by wild‐type and oncogenic Vav‐2

No abstract is available for this paper.

• Publication year

  1998

• Venue

  EMBO Journal

• Publication date

  1998-11-16

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/emboj/17.22.6608PMID 9822605PMCID PMC1171007
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells.

  1998cited by this paper
• Rho GTPases and the actin cytoskeleton.

  1998influential reference
• Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav.

  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
• Rho GTPases and signaling networks.

  1997cited by this paper
• Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

  1997cited by this paper
• Tyrosine Phosphorylation of the vav Proto-oncogene Product Links FcεRI to the Rac1-JNK Pathway*

  1997cited by this paper
• Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways.

  1996cited by this paper
• The VAV family of signal transduction molecules.

  1996cited by this paper
• The Dbl family of oncogenes.

  1996influential reference
• Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes.

  1996cited by this paper
• Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

  1995influential reference
• Intrinsic and GTPase-activating protein-stimulated Ras GTPase assays.

  1995influential reference
• Guanine nucleotide exchange catalyzed by dbl oncogene product.

  1995influential reference
• Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1

  1994cited by this paper
• Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho

  1994cited by this paper
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  1994cited by this paper
• Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity.

  1994cited by this paper
• Proteins regulating Ras and its relatives

  1993influential reference
• Tyrosine Phosphorylation of the vav Proto-Oncogene Product in Activated B Cells

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• Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential

  1991influential reference
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• New insights into the Vav1 activation cycle in lymphocytes.

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• Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through nuclear factor (NF)-κB.

  2017influential citation
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  2013cites this paper
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  2013cites this paper
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