Intestinal iron absorption: regulation by dietary & systemic factors.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition

• Publication date

  2010-10-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1024/0300-9831/a000029PMID 21462105
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Transferrin receptor 2 is crucial for iron sensing in human hepatocytes.

  2010cited by this paper
• Interaction of calcium with the human divalent metal-ion transporter-1.

  2010cited by this paper
• Bioactive dietary polyphenols decrease heme iron absorption by decreasing basolateral iron release in human intestinal Caco-2 cells.

  2010cited by this paper
• Quercetin is a substrate for the transmembrane oxidoreductase Dcytb.

  2010cited by this paper
• Erythropoietin regulates intestinal iron absorption in a rat model of chronic renal failure.

  2010cited by this paper
• Inhibitory effect of calcium on non-heme iron absorption may be related to translocation of DMT-1 at the apical membrane of enterocytes.

  2010cited by this paper
• Serum hepcidin is significantly associated with iron absorption from food and supplemental sources in healthy young women.

  2009cited by this paper
• Contribution of STAT3 and SMAD4 pathways to the regulation of hepcidin by opposing stimuli.

  2009cited by this paper
• Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression.

  2009cited by this paper
• Plasma hepcidin concentrations significantly predict interindividual variation in iron absorption in healthy men.

  2009cited by this paper
• HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.

  2009cited by this paper
• Hepcidin in obese children as a potential mediator of the association between obesity and iron deficiency.

  2009cited by this paper
• Plasma hepcidin is a modest predictor of dietary iron bioavailability in humans, whereas oral iron loading, measured by stable‐isotope appearance curves, increases plasma hepcidin

  2009cited by this paper
• Hepcidin is elevated in mice injected with Mycoplasma arthritidis

  2009cited by this paper
• Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency.

  2009cited by this paper
• Increased serum hepcidin-25 level and increased tumor expression of hepcidin mRNA are associated with metastasis of renal cell carcinoma

  2009cited by this paper
• A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis

  2009cited by this paper
• Hepcidin decreases iron transporter expression in vivo in mouse duodenum and spleen and in vitro in THP-1 macrophages and intestinal Caco-2 cells.

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• Circulating hepcidin in the crossroads of anemia and inflammation associated with rheumatoid arthritis.

  2009cited by this paper
• Involvement of Hepcidin in the Anemia of Multiple Myeloma

  2008cited by this paper
• Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum.

  2008cited by this paper
• Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPα

  2008cited by this paper
• Effect of erythropoietin on hepcidin, DMT1 with IRE, and hephaestin gene expression in duodenum of rats

  2008cited by this paper
• Proteomic profiling of urine for the detection of colon cancer

  2008cited by this paper
• Increased hepcidin expression in colorectal carcinogenesis.

  2008cited by this paper
• Bioactive dietary polyphenolic compounds reduce nonheme iron transport across human intestinal cell monolayers.

  2008cited by this paper
• Duodenal cytochrome B expression stimulates iron uptake by human intestinal epithelial cells.

  2008cited by this paper
• Dcytb (Cybrd1) functions as both a ferric and a cupric reductase in vitro

  2008cited by this paper
• Ascorbic acid uptake affects ferritin, Dcytb and Nramp2 expression in Caco-2 cells

  2008cited by this paper
• Immunoassay for human serum hepcidin.

  2008cited by this paper
• L-alpha-glycerophosphocholine contributes to meat's enhancement of nonheme iron absorption.

  2008cited by this paper
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  2008cited by this paper
• Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1).

  2007cited by this paper
• Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells

  2007cited by this paper
• Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.

  2007cited by this paper
• Proton pump inhibitors suppress absorption of dietary non-haem iron in hereditary haemochromatosis

  2007cited by this paper
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  2007cited by this paper
• Molecular mechanisms involved in intestinal iron absorption.

  2007cited by this paper
• Hereditary Hemochromatosis Protein, HFE, Interaction with Transferrin Receptor 2 Suggests a Molecular Mechanism for Mammalian Iron Sensing*

  2006cited by this paper
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  2006cited by this paper
• Decreased hephaestin activity in the intestine of copper-deficient mice causes systemic iron deficiency.

  2006cited by this paper
• Increased adipose tissue expression of hepcidin in severe obesity is independent from diabetes and NASH.

  2006cited by this paper
• Three mammalian cytochromes b561 are ascorbate‐dependent ferrireductases

  2006cited by this paper
• Tumour necrosis factor alpha causes hypoferraemia and reduced intestinal iron absorption in mice.

  2006cited by this paper
• A role for tumour necrosis factor alpha in human small bowel iron transport.

  2005cited by this paper
• Duodenal ascorbate and ferric reductase in human iron deficiency.

  2005cited by this paper
• Identification of an intestinal heme transporter.

  2005cited by this paper
• Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice.

  2005cited by this paper
• Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs.

  2005cited by this paper
• The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis.

  2005cited by this paper
• Regulation of divalent metal transporter expression in human intestinal epithelial cells following exposure to non‐haem iron

  2005cited by this paper
• Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis

  2004cited by this paper
• IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin.

  2004cited by this paper
• The Stem Cell Marker Bcrp/ABCG2 Enhances Hypoxic Cell Survival through Interactions with Heme*

  2004cited by this paper
• Carbohydrate fractions from cooked fish promote iron uptake by Caco-2 cells.

  2004cited by this paper
• Inhibition of iron transport across human intestinal epithelial cells by hepcidin.

  2004cited by this paper
• Tumour necrosis factor alpha regulates iron transport and transporter expression in human intestinal epithelial cells

  2004cited by this paper
• Identification of a human heme exporter that is essential for erythropoiesis.

  2004cited by this paper
• The molecular basis of copper and iron interactions

  2004cited by this paper
• Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein.

  2003cited by this paper
• Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis

  2003cited by this paper
• Increasing the cooking temperature of meat does not affect nonheme iron absorption from a phytate-rich meal in women.

  2003cited by this paper
• Ctr1 and its role in body copper homeostasis.

  2003cited by this paper
• A rapid decrease in the expression of DMT1 and Dcytb but not Ireg1 or hephaestin explains the mucosal block phenomenon of iron absorption

  2003cited by this paper
• Rapid regulation of divalent metal transporter (DMT1) protein but not mRNA expression by non‐haem iron in human intestinal Caco‐2 cells

  2002cited by this paper
• Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats.

  2002cited by this paper
• Histidine content of low-molecular-weight beef proteins influences nonheme iron bioavailability in Caco-2 cells.

  2002cited by this paper
• Hepcidin, a new iron regulatory peptide.

  2002cited by this paper
• Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease.

  2002cited by this paper
• The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation.

  2002cited by this paper
• Hemochromatosis protein (HFE) and tumor necrosis factor receptor 2 (TNFR2) influence tissue iron levels: elements of a common gut pathway?

  2002cited by this paper
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  2002cited by this paper
• An Iron-Regulated Ferric Reductase Associated with the Absorption of Dietary Iron

  2001cited by this paper
• Hepcidin, a Urinary Antimicrobial Peptide Synthesized in the Liver*

  2001cited by this paper
• A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload*

  2001cited by this paper
• Dietary iron induces rapid changes in rat intestinal divalent metal transporter expression.

  2000cited by this paper
• A Novel Mammalian Iron-regulated Protein Involved in Intracellular Iron Metabolism*

  2000cited by this paper
• LEAP‐1, a novel highly disulfide‐bonded human peptide, exhibits antimicrobial activity

  2000cited by this paper
• Nramp2 Expression Is Associated with pH-dependent Iron Uptake across the Apical Membrane of Human Intestinal Caco-2 Cells*

  2000cited by this paper
• Gastrointestinal function, divalent metal transporter-1 expressionand intestinal iron absorption

  2000cited by this paper
• Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

  2000cited by this paper
• A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation.

  2000cited by this paper
• Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload

  2000cited by this paper
• Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse

  1999cited by this paper
• Gamma delta intraepithelial lymphocytes drive tumor necrosis factor-alpha responsiveness to intestinal iron challenge: relevance to hemochromatosis.

  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
• Cloning and characterization of a mammalian proton-coupled metal-ion transporter

  1997cited by this paper
• The leptin receptor mediates apparent autocrine regulation of leptin gene expression.

  1997cited by this paper
• Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

  1997cited by this paper
• Serum immunoreactive-leptin concentrations in normal-weight and obese humans.

  1996cited by this paper
• Mechanism underlying the inhibitory effect of high calcium carbonate intake on iron bioavailability from ferrous sulphate in anaemic rats

  1996cited by this paper
• Identification and characterization of a second mouse Nramp gene.

  1995cited by this paper
• Positional cloning of the mouse obese gene and its human homologue

  1994cited by this paper
• Serum Erythropoietin Levels in Elderly Inpatients with Anemia of Chronic Disorders and Iron Deficiency Anemia

  1993cited by this paper
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  1992cited by this paper
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  1991cited by this paper
• Calcium: effect of different amounts on nonheme- and heme-iron absorption in humans.

  1991cited by this paper
• Ascorbic acid safety: analysis of factors affecting iron absorption.

  1990cited by this paper
• Iron absorption in man: ascorbic acid and dose-dependent inhibition by phytate.

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