Molecular characterization of an enterobacterial metallo beta-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Antimicrobial Agents and Chemotherapy

• Publication date

  1994-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/AAC.38.1.71PMID 8141584PMCID PMC284399
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cloning and expression of the gene(s) for cephalosporinase production of Citrobacter freundii

  2004cited by this paper
• Plasmid-mediated AmpC-type beta-lactamase isolated from Klebsiella pneumoniae confers resistance to broad-spectrum beta-lactams, including moxalactam

  1993cited by this paper
• Kinetic interactions of tazobactam with beta-lactamases from all major structural classes

  1993cited by this paper
• Conjugal transfer of imipenem resistance in Bacteroides fragilis.

  1992cited by this paper
• Interplay of impermeability and chromosomal beta-lactamase activity in imipenem-resistant Pseudomonas aeruginosa

  1992cited by this paper
• More extended-spectrum beta-lactamases

  1991cited by this paper
• Transferable imipenem resistance in Pseudomonas aeruginosa

  1991cited by this paper
• The Aeromonas hydrophila cphA gene: molecular heterogeneity among class B metallo-beta-lactamases

  1991cited by this paper
• Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically

  1990cited by this paper
• Cloning, sequencing and analysis of the structural gene and regulatory region of the Pseudomonas aeruginosa chromosomal ampC beta-lactamase.

  1990cited by this paper
• Novel plasmid-mediated beta-lactamase (MIR-1) conferring resistance to oxyimino- and alpha-methoxy beta-lactams in clinical isolates of Klebsiella pneumoniae

  1990cited by this paper
• Cloning and sequencing of the class B beta-lactamase gene (ccrA) from Bacteroides fragilis TAL3636

  1990cited by this paper
• Biochemical characterization of a beta-lactamase that hydrolyzes penems and carbapenems from two Serratia marcescens isolates

  1990influential reference
• Nucleotide sequence of the Serratia marcescens SR50 chromosomal ampC beta-lactamase gene.

  1990cited by this paper
• Plasmid-mediated beta-lactamases in clinical isolates of Klebsiella pneumoniae and Escherichia coli resistant to ceftazidime

  1989cited by this paper
• Chromosomal beta-lactamase of Klebsiella oxytoca, a new class A enzyme that hydrolyzes broad-spectrum beta-lactam antibiotics

  1989cited by this paper
• NovelPlasmid-Mediated 3-Lactamase fromEscherichia coli That Inactivates Oxyimino-Cephalosporins

  1988cited by this paper
• Sequence and comparative analysis of three Enterobacter cloacae ampC beta-lactamase genes and their products.

  1988cited by this paper
• Novel plasmid-mediated beta-lactamase from Escherichia coli that inactivates oxyimino-cephalosporins

  1988cited by this paper
• Dissemination of the novel plasmid-mediated beta-lactamase CTX-1, which confers resistance to broad-spectrum cephalosporins, and its inhibition by beta-lactamase inhibitors

  1988cited by this paper
• Cloning, nucleotide sequence, and expression of the Bacillus cereus 5/B/6 beta-lactamase II structural gene

  1988cited by this paper
• Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns.

  1988cited by this paper
• Novel plasmid-mediated beta-lactamase in clinical isolates of Klebsiella pneumoniae more resistant to ceftazidime than to other broad-spectrum cephalosporins

  1988cited by this paper
• Chromosomal cephalosporinases responsible for multiple resistance to newer beta-lactam antibiotics.

  1987cited by this paper
• High-copy-number and low-copy-number plasmid vectors for lacZ alpha-complementation and chloramphenicol- or kanamycin-resistance selection.

  1987cited by this paper
• Novel beta-lactamase in a clinical isolate of Klebsiella pneumoniae conferring unusual resistance to beta-lactam antibiotics.

  1987cited by this paper
• An X-ray-crystallographic study of beta-lactamase II from Bacillus cereus at 0.35 nm resolution.

  1987cited by this paper
• Sequence of the Citrobacter freundii OS60 chromosomal ampC beta-lactamase gene.

  1986cited by this paper
• Close evolutionary relationship between the chromosomally encoded beta-lactamase gene of Klebsiella pneumoniae and the TEM beta-lactamase gene mediated by R plasmids.

  1986cited by this paper
• Methodology for the study of beta-lactamases

  1986cited by this paper
• Emergence of resistance to imipenem during therapy for Pseudomonas aeruginosa infections.

  1986cited by this paper
• Close evolutionary relationship between the chromosomally encoded β lactamase gene of Klebsiella pneumoniae and the TEM β‐lactamase gene mediated by R plasmids

  1986cited by this paper
• Beta-lactamase-mediated imipenem resistance in Bacteroides fragilis

  1986cited by this paper
• Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors.

  1985cited by this paper
• Chromosomal beta-lactamases of Enterobacter cloacae are responsible for resistance to third-generation cephalosporins

  1983cited by this paper
• Properties of novel beta-lactamase produced by Bacteroides fragilis

  1983cited by this paper
• Detection of specific sequences among DNA fragments separated by gel electrophoresis.

  1975cited by this paper

• Ceftazidime-avibactam resistance among clinical isolates of Citrobacter freundii, Morganella morganii, Providencia spp. and Serratia marcescens across five continents: Data from the Antimicrobial Testing Leadership and Surveillance (ATLAS) programme, 2016-2023.

  2025cites this paper
• Activity of aztreonam-avibactam, cefiderocol, and cefepime-taniborbactam against a global collection of genetically characterized metallo-β-lactamase-producing Enterobacterales

  2025cites this paper
• Biochemical properties and substrate specificity of GOB-38 in Elizabethkingia anophelis

  2025cites this paper
• Past, present, and future perspectives on aztreonam and avibactam

  2025cites this paper
• Antibiotic resistance genes in Escherichia coli – literature review

  2025cites this paper
• The genetic context of blaIMP varies among bacterial families from One Health sources

  2025cites this paper
• Horizontal Gene Transfer Systems for Spread of Antibiotic Resistance in Gram‐Negative Bacteria

  2025cites this paper
• Genetic Basis of Carbapenem-Resistant Clinical Serratia marcescens in Japan.

  2025cites this paper
• The emerging concern of IMP variants being resistant to the only IMP-type metallo-β-lactamase inhibitor, xeruborbactam

  2025cites this paper
• Molecular characterization of a clinical ST145 Klebsiella oxytoca strain co-producing KPC-2 and IMP-96 carbapenemases

  2025cites this paper
• Beyond the Spotlight: Enterobacter spp. as Overlooked Carbapenemase Producers in Europe

  2025cites this paper
• Tackling Carbapenem Resistance and the Imperative for One Health Strategies—Insights from the Portuguese Perspective

  2024cites this paper
• Development of Inhibitory Compounds for Metallo-beta-lactamase through Computational Design and Crystallographic Analysis.

  2024cites this paper
• The characterization of an IncN-IncR fusion plasmid co-harboring blaTEM−40, blaKPC−2, and blaIMP−4 derived from ST1393 Klebsiella pneumoniae

  2024cites this paper
• Genomic analysis of IMP-8-producing Enterobacter hormaechei with a novel plasmid pK432-IMP.

  2024cites this paper
• Correlation between the spread of IMP-producing bacteria and the promoter strength of blaIMP genes

  2024cites this paper
• Clinical and genomic characteristics of IMP-producing Enterobacter cloacae complex and Klebsiella pneumoniae

  2024cites this paper
• Functional and structural analyses of IMP-27 metallo-β-lactamase: evolution of IMP-type enzymes to overcome Zn(II) deprivation

  2024cites this paper
• Carbapenem-Resistant Enterobacterales in the Western Balkans: Addressing Gaps in European AMR Surveillance Map

  2024cites this paper
• Emergence of Aztreonam/Avibactam and Tigecycline-Resistant Pseudomonas putida group Co-producing blaIMP-1, blaAFM-4 and blaOXA-1041 With a Novel Sequence Type ST268 in Southwestern China.

  2024cites this paper
• MACI: A machine learning-based approach to identify drug classes of antibiotic resistance genes from metagenomic data

  2023cites this paper
• Review and analysis of the overlapping threats of carbapenem and polymyxin resistant E. coli and Klebsiella in Africa

  2023cites this paper
• Evaluation of the BD Phoenix CPO Detect Panel for Detection and Classification of Carbapenemase Producing Enterobacterales

  2023cites this paper
• INFECTIOUS COMPLICATIONS, ASSOCIATED WITH MULTI-DRUG RESISTANT BACTERIA IN PATIENTS FOLLOWING HEMATOPOIETIC STEM CELL TRANSPLANTATION – RESISTANCE MECHANISMS AND THERAPEUTIC OPTIONS

  2023cites this paper
• Screening for Metallo-Beta-Lactamases Using Non-Carbapenem Agents: Effective Detection of MBL-Producing Enterobacterales and Differentiation of Carbapenem-Resistant Enterobacterales

  2023cites this paper
• Strategies to Name Metallo-β-Lactamases and Number Their Amino Acid Residues

  2023influential citation
• Visualizing and quantifying structural diversity around mobile resistance genes

  2023cites this paper
• Antibiotic resistance in Enterobacter hormaechei.

  2022cites this paper
• The first report of the blaIMP-10 gene and complete sequence of the IMP-10-encoding plasmid p12NE515 from Pseudomonas aeruginosa in China.

  2022cites this paper
• What role does organic fertilizer actually play in the fate of antibiotic resistome and pathogenic bacteria in planting soil?

  2022cites this paper
• [Regional dissemination of carbapenem-resistant Enterobacteriaceae accompanying with enhanced resistance in Northern Osaka, Japan].

  2022cites this paper
• Structure and Mechanism-Guided Design of Dual Serine/Metallo-Carbapenemase Inhibitors.

  2022cites this paper
• Structural insights into the substrate specificity of IMP-6 and IMP-1 metallo-β-lactamases

  2022cites this paper
• Difference in the Inhibitory Effect of Thiol Compounds and Demetallation Rates from the Zn(II) Active Site of Metallo-β-lactamases (IMP-1 and IMP-6) Associated with a Single Amino Acid Substitution.

  2022cites this paper
• Structural insights into the design of reversible fluorescent probes for metallo-β-lactamases NDM-1, VIM-2, and IMP-1.

  2022cites this paper
• Impact of carbapenem resistance on mortality in patients infected with Enterobacteriaceae: a systematic review and meta-analysis

  2021cites this paper
• Identification of the Inhibitory Compounds for Metallo-β-lactamases and Structural Analysis of the Binding Modes.

  2021cites this paper
• The Synthesis and Evaluation of Aminocoumarin Peptidomimetics as Cytotoxic Agents on Model Bacterial E. coli Strains

  2021cites this paper
• Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants

  2021cites this paper
• Subtype screening of blaIMP genes using bipartite primers for DNA sequencing.

  2021cites this paper
• Evaluation of Disk carbapenemase test using improved disks for rapid detection and differentiation of clinical isolates of carbapenemase-producing Enterobacterales.

  2021cites this paper
• Metallo-β-lactamases in the Age of Multidrug Resistance: From Structure and Mechanism to Evolution, Dissemination, and Inhibitor Design.

  2021cites this paper
• Differences in antimicrobial susceptibility testing complicating management of IMP carbapenemase-producing Enterobacterales infection.

  2021cites this paper
• Spectroscopic and biochemical characterization of metallo-β-lactamase IMP-1 with dicarboxylic, sulfonyl, and thiol inhibitors.

  2021cites this paper
• Current situation of carbapenem‐resistant Enterobacteriaceae and Acinetobacter in Japan and Southeast Asia

  2021cites this paper
• The Potential Use of Ceftazidime-Avibactam Against Carbapenem Resistant Klebsiella pneumoniae Clinical Isolates Harboring Different Carbapenemase Types in a Thai University Hospital

  2021cites this paper
• Characterization of a rare blaVIM-4 metallo-β-lactamase-producing Serratia marcescens clinical isolate in Hungary

  2020cites this paper
• Recent Progress of Fluorogenic Probes/Inhibitors of β-Lactamase and their Applications in Drug-Resistant Bacteria.

  2020cites this paper
• Imipenem Resistance Mechanisms in Multidrug Resistant Pseudomonas aeruginosa clinical isolates from south India

  2020cites this paper
• Metallo-β-Lactamase Inhibitors Inspired on Snapshots from the Catalytic Mechanism

  2020cites this paper
• Trends and molecular characteristics of carbapenemase-producing Enterobacteriaceae in Japanese hospital from 2006 to 2015.

  2020cites this paper
• Carbapenemases: Transforming Acinetobacter baumannii into a Yet More Dangerous Menace

  2020cites this paper
• First and broad detection of three typical carbapenemase genes on the surfaces of commercially available spices worldwide and isolation of complete NDM-1 genes from black pepper, cumin, and clove

  2020cites this paper
• The role of the natural aquatic environment in the dissemination of extended spectrum beta-lactamase and carbapenemase encoding genes: A scoping review.

  2020cites this paper
• RNA-hydrolyzing activity of metallo-β-lactamase IMP-1

  2020cites this paper
• Molecular Characteristics of Carbapenem-Resistant Enterobacter cloacae in a Tertiary Hospital in China

  2020cites this paper
• Regional Dissemination of a Carbapenemase-encoding Plasmid: Plasmidome analysis Reveals Diverse Adaptations of Carbapenemase-Producing Enterobacteriaceae

  2020influential citation
• Systematic research to overcome newly emerged multidrug‐resistant bacteria

  2020cites this paper
• Genetics of Acquired Antibiotic Resistance Genes in Proteus spp.

  2020cites this paper
• Characterization of the Plasmidome Encoding Carbapenemase and Mechanisms for Dissemination of Carbapenem-Resistant <italic toggle='yes'>Enterobacteriaceae</italic>

  2020cites this paper
• Epidemiology of β-Lactamase-Producing Pathogens

  2020cites this paper
• Trade-Offs between Antibacterial Resistance and Fitness Cost in the Production of Metallo-β-Lactamases by Enteric Bacteria Manifest as Sporadic Emergence of Carbapenem Resistance in a Clinical Setting

  2020cites this paper
• Geographical distribution of Enterobacterales with a carbapenemase IMP-6 phenotype and its association with antimicrobial use: An analysis using comprehensive national surveillance data on antimicrobial resistance

  2020cites this paper
• Characterization of the Plasmidome Encoding Carbapenemase and Mechanisms for Dissemination of Carbapenem-Resistant Enterobacteriaceae

  2020influential citation
• Serratia marcescens.

  2020cites this paper
• Treatment of severe infections due to metallo-β-lactamases-producing Gram-negative bacteria.

  2020cites this paper
• Molecular Epidemiology of Emerging Carbapenem Resistance in Acinetobacter nosocomialis and Acinetobacter pittii in Taiwan, 2010 to 2014

  2019cites this paper
• A Multidrug Resistance Plasmid pIMP26, Carrying blaIMP-26, fosA5, blaDHA-1, and qnrB4 in Enterobacter cloacae

  2019cites this paper
• Distribution and molecular characterization of beta-lactamases in Gram-negative bacteria in Colombia, 2001-2016

  2019cites this paper
• Identification of Diverse Integron and Plasmid Structures Carrying a Novel Carbapenemase Among Pseudomonas Species

  2019cites this paper
• 4-Amino-2-Sulfanylbenzoic Acid as a Potent Subclass B3 Metallo-β-Lactamase-Specific Inhibitor Applicable for Distinguishing Metallo-β-Lactamase Subclasses

  2019influential citation
• CARBAPENEM-RESISTANT ENTEROBACTERIACEAE : EPIDEMIOLOGY, GENETICS, IN VITRO ACTIVITY, AND PHARMACODYNAMIC MODELING

  2019influential citation
• [Molecular biological studies toward controlling infectious diseases caused by multidrug-resistant Pseudomonas aeruginosa].

  2019cites this paper
• Correlation study of antibacterial activity and spectrum of Penicillins through a structure-activity relationship analysis

  2019cites this paper
• Therapeutic nanostructures: novel approaches

  2019cites this paper
• Mutation S115T in IMP-Type Metallo-β-Lactamases Compensates for Decreased Expression Levels Caused by Mutation S119G

  2019influential citation
• The pollution level of the blaOXA-58 carbapenemase gene in coastal water and its host bacteria characteristics.

  2019cites this paper
• Serratia marcescens Infections in Neonatal Intensive Care Units (NICUs)

  2019cites this paper
• Treatment Options for Carbapenem-resistant Gram-negative Bacterial Infections

  2019cites this paper
• ZHO-1, an intrinsic MBL from the environmental Gram-negative species Zhongshania aliphaticivorans.

  2019cites this paper
• How to discover new antibiotic resistance genes?

  2019cites this paper
• Carbapenemase-producing bacteria in food-producing animals, wildlife and environment: A challenge for human health

  2019cites this paper
• Beta-lactam resistance among Enterobacteriaceae in Cambodia: The four-year itch.

  2018cites this paper
• First reported nosocomial outbreak of Serratia marcescens harboring blaIMP-4 and blaVIM-2 in a neonatal intensive care unit in Cairo, Egypt

  2018cites this paper
• SIGNIFICANCE OF URINARY TRACT INFECTION BY ENTEROBACTER, CITROBCATER AND SERRATIA SPECIES AND THEIR ANTIMICROBIAL SUSCEPTIBILITY PROFILE WITH SPECIAL REFERNCE TO INTRINSIC RESISTANCE

  2018cites this paper
• Antimicrobial susceptibility and characterization of metallo-β-lactamases, extended-spectrum β-lactamases, and carbapenemases of Bacillus cereus isolates.

  2018cites this paper
• Review and mapping of carbapenem-resistant Enterobacteriaceae in Africa: Using diverse data to inform surveillance gaps.

  2018cites this paper
• Pharmacological aspects and spectrum of action of ceftazidime–avibactam: a systematic review

  2018cites this paper
• Carbapenemase-producing Enterobacteriaceae in South Korea: a report from the National Laboratory Surveillance System.

  2018cites this paper
• Synonymous lysine codon usage modification in a mobile antibiotic resistance gene similarly alters protein production in bacterial species with divergent lysine codon usage biases because it removes a duplicate AAA lysine codon

  2018cites this paper
• Identification of blaVIM, blaIMP and blaSPM-1 Metallo-β-Lactamase Genes in Bacillus subtilis Strains Isolated From Raw Milk and Cheese Samples

  2018cites this paper
• Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

  2018cites this paper
• Urkund Analysis Result

  2018cites this paper
• Diversity and Proliferation of Metallo-β-Lactamases: a Clarion Call for Clinically Effective Metallo-β-Lactamase Inhibitors

  2018cites this paper
• Current Trends in Antimicrobial Resistance of Escherichia coli.

  2018cites this paper
• Boric acid and acetate anion binding to subclass B3 metallo-β-lactamase BJP-1 provides clues for mechanism of action and inhibitor design

  2018cites this paper
• Biochemical and genetic characterization of a novel metallo-β-lactamase from marine bacterium Erythrobacter litoralis HTCC 2594

  2018cites this paper
• The molecular mechanisms underlying hidden phenotypic variation among metallo-ß-lactamases

  2018cites this paper
• Metallo-β-lactamases and class D carbapenemases in south-east Tunisia: Implication of mobile genetic elements in their dissemination.

  2018cites this paper
• Carbapenem-Resistant Enterobacteriaceae.

  2017cites this paper