Redox Control of Leukemia: From Molecular Mechanisms to Therapeutic Opportunities

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Antioxidants and Redox Signaling

• Publication date

  2013-04-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1089/ars.2011.4258PMID 22900756PMCID PMC3584825
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Glutathione.

  2015influential reference
• Mitochondrial Regulation of Cell Cycle and Proliferation

  2012cited by this paper
• Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene.

  2012influential reference
• Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia

  2012influential reference
• Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessment.

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  2011influential reference
• Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells.

  2011influential reference
• Inhibition of heme oxygenase-1 enhances anti-cancer effects of arsenic trioxide on glioma cells

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• Association of Glutathione S-Transferase, EPHX, and p53 codon 72 Gene Polymorphisms with Adult Acute Myeloid Leukemia

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• Selective killing of cancer cells with a small molecule targeting stress response to ROS

  2011influential reference
• Signal transduction by reactive oxygen species

  2011cited by this paper
• High basal nuclear levels of Nrf2 in acute myeloid leukemia reduces sensitivity to proteasome inhibitors.

  2011influential reference
• Effects of Stem Cell Factor on Hypoxia-Inducible Factor 1 Alpha Accumulation in Human Acute Myeloid Leukaemia and LAD2 Mast Cells

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• NADPH oxidase inhibitors: a patent review

  2011cited by this paper
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• Inhibition of thioredoxin reductase by auranofin induces apoptosis in adriamycin-resistant human K562 chronic myeloid leukemia cells.

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• Cytarabine dose for acute myeloid leukemia.

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  2010influential reference
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  2010influential reference
• Antioxidant enzymes activities and plasma levels of oxidative stress markers in B-chronic lymphocytic leukemia patients.

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  2009influential reference
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• Evolution of Catalases from Bacteria to Humans

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