Risk of coronary heart disease and activation of factor XII in middle-aged men.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Arteriosclerosis, Thrombosis and Vascular Biology

• Publication date

  1997-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/01.ATV.17.10.2103PMID 9351378
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Increased Activation of the Haemostatic System in Men at High Risk of Fatal Coronary Heart Disease

  1996cited by this paper
• An enzyme-linked immunosorbent assay (ELISA) for the measurement of activated factor XII (Hageman factor) in human plasma.

  1996cited by this paper
• Risk factors for cerebrovascular disease and the role of coagulation and fibrinolysis.

  1995cited by this paper
• Factor VII-Deficient Substrate Plasmas Depleted of Protein C Raise the Sensitivity of the Factor VII Bio-Assay to Activated Factor VII: an International Study

  1994cited by this paper
• Mechanisms of thrombin generation during surgery and cardiopulmonary bypass [see comments]

  1993cited by this paper
• Hageman factor and risk of myocardial infarction in middle-aged men.

  1992cited by this paper
• The Autoactivation of Factor XII in the Presence of Long-Chain Saturated Fatty Acids – A Comparison with the Potency of Sulphatides and Dextran Sulphate

  1991cited by this paper
• Thromboembolism and Bleeding Tendency in Congenital Factor XII DeficienCy - A Study on 74 Subjects from 14 Swiss Families

  1991cited by this paper
• The Increased Rate of Activation of Factor XII in Late Pregnancy Can Contribute to the Increased Reactivity of Factor VII

  1990cited by this paper
• Augmented Hageman factor and prolactin titers, enhanced cold activation of factor VII, and spontaneous shortening of prothrombin time in survivors of myocardial infarction.

  1987cited by this paper
• The coagulation-kinin pathway of human plasma

  1987cited by this paper
• The coagulation-kinin pathway of human plasma.

  1987cited by this paper
• Effect of negatively charged activating compounds on inactivation of factor XIIa by Cl inhibitor.

  1987cited by this paper
• Haemostatic function and ischaemic heart disease: principal results of the Northwick Park Heart Study.

  1986cited by this paper
• Activation of factor XII and prekallikrein with cholesterol sulfate.

  1985cited by this paper
• Assessment of Hageman factor activation in human plasma: quantification of activated Hageman factor-C1 inactivator complexes by an enzyme-linked differential antibody immunosorbent assay.

  1985cited by this paper
• The contact phase of blood coagulation and renin activation in essential hypertension before and after captopril.

  1984cited by this paper
• In vitro activation of the contact (Hageman factor) system of plasma by heparin and chondroitin sulfate E.

  1984cited by this paper
• Mechanisms of activation of the classical pathway of complement by Hageman factor fragment.

  1983cited by this paper
• A comparison of the abilities of plasma kallikrein, beta-Factor XIIa, Factor XIa and urokinase to activate plasminogen.

  1983cited by this paper
• The role of augmented Hageman factor (factor XII) titers in the cold-promoted activation of factor VII and spontaneous shortening of the prothrombin time in women using oral contraceptives.

  1982cited by this paper
• Identification of plasma kallikrein as an activator of latent collagenase in rheumatoid synovial fluid.

  1982cited by this paper
• Haemostasis and thrombosis

  1981cited by this paper
• Activation of human factor VII in plasma and in purified systems: roles of activated factor IX, kallikrein, and activated factor XII.

  1979cited by this paper
• An intrinsic factor XII–prekallikrein-dependent pathway activates the human plasma renin–angiotensin system

  1979cited by this paper
• Human high molecular weight kininogen. Studies of structure-function relationships and of proteolysis of the molecule occurring during contact activation of plasma.

  1979cited by this paper
• Kallikrein and plasmin as activators of inactive renin.

  1978cited by this paper
• KALLIKREIN AND PLASMIN AS ACTIVATORS OF INACTIVE RENIN

  1978cited by this paper
• Hageman factor substrates. Human plasma prekallikrein: mechanism of activation by Hageman factor and participation in hageman factor-dependent fibrinolysis.

  1977cited by this paper
• Human blood coagulation factor XI. Purification, properties, and mechanism of activation by activated factor XII.

  1977cited by this paper
• DIRECT EVIDENCE FOR HAGEMAN FACTOR (FACTOR XII) ACTIVATION BY BACTERIAL LIPOPOLYSACCHARIDES (ENDOTOXINS)

  1974cited by this paper
• THE INFLAMMATORY PROCESS IN ACUTE GOUTY ARTHRITIS. I. ACTIVATION OF HAGEMAN FACTOR BY SODIUM URATE CRYSTALS.

  1965cited by this paper
• The Contact Phase of Blood Coagulation

  1964cited by this paper
• THE ACCELERATION OF THROMBUS FORMATION BY CERTAIN FATTY ACIDS.

  1962cited by this paper
• The Activation of Christmas Factor (Factor IX) by Activated Plasma Thromboplastin Antecedent (Activated Factor XI)

  1962cited by this paper
• Gerinnungsphysiologische Schnellmethode zur Bestimmung des Fibrinogens

  1957cited by this paper
• [Rapid physiological coagulation method in determination of fibrinogen].

  1957cited by this paper

• The Perspectives of Platelet Proteomics in Health and Disease

  2024cites this paper
• Elevated plasma FXII is associated with disease activity in ANCA-associated vasculitis: A Retrospective Cross-Sectional Study in Western China.

  2023cites this paper
• F12 as a reliable diagnostic and prognostic biomarker associated with immune infiltration in papillary thyroid cancer

  2022cites this paper
• Factor XII Concentrations and Risk of Intracerebral Haemorrhage. A Prospective Case-Referent Study.

  2021cites this paper
• The versatile role of the contact system in cardiovascular disease, inflammation, sepsis and cancer.

  2021cites this paper
• Impact of Deficiency of Intrinsic Coagulation Factors XI and XII on Ex Vivo Thrombus Formation and Clot Lysis

  2019cites this paper
• Inhibition of Blood Coagulation Factor XII: Evaluation of Flavonoids as a Drug Candidate

  2018cites this paper
• Factor XII as a Risk Marker for Hemorrhagic Stroke: A Prospective Cohort Study

  2017cites this paper
• Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases

  2017cites this paper
• FXII (46 C R T) Polymorphism and In Vivo Generation of FXII Activity Gene Frequencies and Relationship in Patients with Coronary Artery Disease

  2017influential citation
• Evidence of contact activation in patients suffering from ST-elevation myocardial infarction.

  2016cites this paper
• Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice

  2016cites this paper
• Factor XII in Hemostasis and Thrombosis: Active Player or (Innocent) Bystander?

  2016cites this paper
• Paradoxical enhancement of the intrinsic pathway-induced thrombin generation in human plasma by melagatran, a direct thrombin inhibitor, but not edoxaban, a direct factor Xa inhibitor, or heparin.

  2015cites this paper
• Factor XII: a novel target for safe prevention of thrombosis and inflammation

  2015cites this paper
• The hemostatic system as a regulator of inflammation in atherosclerosis

  2014cites this paper
• Circulating Contact-Pathway-Activating Microparticles Together with Factors IXa and XIa Induce Spontaneous Clotting in Plasma of Hematology and Cardiologic Patients

  2014cites this paper
• Factor XII Regulates the Pathological Process of Thrombus Formation on Ruptured Plaques

  2014cites this paper
• The role of coagulation factor XII in fibrin clot formation and fibrinolysis

  2014influential citation
• Activation of the contact system in patients with a first acute myocardial infarction.

  2013cites this paper
• XXVI Corso di aggiornamento ALTERAZIONI CONGENITE ED ACQUISITE DELLA COAGULAZIONE Focus su: SCREENING DI LABORATORIO DELLA TROMBOFILIA GENETICA: QUALE, QUANDO, PERCHÈ

  2012cites this paper
• Humoral innate immune response and disease

  2012cites this paper
• thrombin generation through direct interaction with fibrin Factor XIIa regulates the structure of the fibrin clot independently of

  2012cites this paper
• thrombosis in mice without increased risk of bleeding Selective depletion of plasma prekallikrein or coagulation factor XII inhibits

  2012cites this paper
• Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding.

  2011cites this paper
• Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin.

  2011cites this paper
• Die Stimulierung des Kontaktaktivierungssystems der menschlichen Blutgerinnung durch Lipoprotein-assoziierte Phospholipide

  2011cites this paper
• Contribution of Activated Coagulation Factor XII to Hypertension in Chronic Renal Failure: Investigation Involving Dialysis Patients and the 5/6 Nephrectomized Uremic Rat

  2011influential citation
• Biochemistry of Hemostasis

  2011cites this paper
• Impact of biomarkers for endothelial dysfunction and procoagulant state on 10‐year cardiovascular risk in Type 2 diabetes 1

  2011cites this paper
• Original clinical investigation A history of late and very late stent thrombosis is not associated with increased activation of the contact system, a case control study

  2010cites this paper
• Cardiovascular Disease, Disturbances of Blood Coagulation and Fibrinolysis

  2010cites this paper
• Association of FXII 5'UTR 46C>T polymorphism with FXII activity and risk of thrombotic disease.

  2010cites this paper
• Association of FXII 5 ’ UTR 46 C > T polymorphism with FXII activity and risk of thrombotic disease FXII 5 ' UTR 46 C >

  2010cites this paper
• Synergism between factor XII –4C>T and factor XIII Val34Leu polymorphisms in fibrinolytic therapy in acute myocardial infarction

  2010cites this paper
• Effects of lead and mercury on the blood proteome of children.

  2010cites this paper
• Correlation of FXII 46CT polymorphism with FXII activity and risk of thrombotic diseases

  2010cites this paper
• Accumulation of Gene Polymorphisms Related to Plaque Disruption and Thrombosis Is Associated With Cerebral Infarction in Subjects With Type 2 Diabetes

  2009cites this paper
• Einfluss von Parametern des Gerinnungssystems und von "brain natriuretic peptide" (BNP) auf die Entstehung von In-Stent-Restenosen bei Patienten mit stabiler koronarer Herzerkrankung-eine Pilotstudie

  2009cites this paper
• Characterization of a Feline Model of Factor XII Deficiency: The In Vivo Role of FXII in Vascular Injury and Inflammatory Responses

  2009cites this paper
• Enhanced atherothrombotic formation after oxidative injury by FeCl3 to the common carotid artery in severe combined hyperlipidemic mice.

  2009cites this paper
• Activated factor XII type A predicts long‐term mortality in patients admitted with chest pain 1

  2009cites this paper
• Alcohol Poisoning and Venous Hyperoxia

  2008cites this paper
• Coagulation factor XII (FXII) activity, activated FXII, distribution of FXII C46T gene polymorphism and coronary risk

  2008cites this paper
• Lower factor XII activity is a risk marker rather than a risk factor for cardiovascular disease: a rebuttal

  2008cites this paper
• A Systematic Review of Risk Scoring Methods and Clinical Decision Aids Used in the Primary Prevention of Coronary Heart Disease (Supplement)

  2008cites this paper
• Diabetes mellitus as a prothrombotic condition

  2007cites this paper
• The intrinsic pathway of coagulation: a target for treating thromboembolic disease?

  2007cites this paper
• Inherited Thrombophilia

  2006cites this paper
• Levels of intrinsic coagulation factors and the risk of myocardial infarction among men: Opposite and synergistic effects of factors XI and XII.

  2006cites this paper
• Effects of VLDL and Remnant Particles on Platelets

  2006cites this paper
• Der Effekt von Abciximab auf die Hämostase, Fibrinolyse sowie die Veränderungen von inflammatorischen Parametern und Adhäsionsmolekülen bei Patienten mit Akutem Koronarsyndrom und PTCA

  2006cites this paper
• Estudio clínico de los factores de riesgo cardiovasculares y su coste farmacológico en una muestra de pacientes derivados a endocrinología desde atención primaria

  2006cites this paper
• Acute coronary syndromes do not promote prolonged in vivo FXII-dependent prothrombotic activity.

  2005influential citation
• Folate Deficiency-Induced Hyperhomocysteinemia Attenuates, and Folic Acid Supplementation Restores, the Functional Activities of Rat Coagulation Factors XII, X, and II 1,2

  2005cites this paper
• Synergistic association between hypercholesterolemia and the C46T factor XII polymorphism for developing premature myocardial infarction

  2005influential citation
• New and old cardiovascular risk factors: C-reactive protein, homocysteine, cysteine and von Willebrand factor increase risk, especially in smokers

  2005cites this paper
• Polimorfismos en la región Kozak del FXII y su relación con el infarto agudo de miocardio prematuro

  2005cites this paper
• Type 2 diabetes: an atherothrombotic syndrome.

  2005cites this paper
• Defective thrombus formation in mice lacking coagulation factor XII

  2005cites this paper
• The impact of cardiac ischemia and reperfusion on markers of activated haemostasis and fibrinolysis during cardiopulmonary bypass: comparison of plasma levels in arterial and coronary venous blood.

  2005cites this paper
• Rebuttal: Factor XII levels, factor XII 46 C>T polymorphism and venous thrombosis: a word of caution is needed

  2004cites this paper
• Homozygosity of the T Allele of the 46 C→T Polymorphism in the F12 Gene Is a Risk Factor for Ischemic Stroke in the Spanish Population

  2004cites this paper
• Association after linkage analysis indicates that homozygosity for the 46C→T polymorphism in the F12 gene is a genetic risk factor for venous thrombosis

  2004cites this paper
• Activated factor 12 (FXIIa) predicts recurrent coronary events after an acute myocardial infarction.

  2004cites this paper
• Parental history of hypertension is associated with coagulation-fibrinolytic balance disorders.

  2003cites this paper
• Insulin resistance ‐ the new goal!

  2003cites this paper
• Plant and marine derived (n-3) polyunsaturated fatty acids do not affect blood coagulation and fibrinolytic factors in moderately hyperlipidemic humans.

  2003cites this paper
• Changes in tissue factor and activated factor XII following an acute myocardial infarction were uninfluenced by high doses of n-3 polyunsaturated fatty acids

  2003cites this paper
• The genetics of atherothrombotic disorders: a clinician's view

  2003cites this paper
• QT prolongation in patients with Type 2 diabetes and microalbuminuria

  2002cites this paper
• Association of the factor XII 46C>T polymorphism with risk of coronary heart disease (CHD) in the WOSCOPS study.

  2002cites this paper
• The contact system.

  2002cites this paper
• Fluctuations in levels of antiphospholipid antibodies and increased coagulation activation markers in normal andheparin-treated antiphospholipid syndrome pregnancies

  2002cites this paper
• Elevated levels of plasma prekallikrein, high molecular weight kininogen and factor XI in coronary heart disease.

  2002cites this paper
• Absence of paradoxical thrombin activation by fibrin-specific thrombolytics in acute myocardial infarction: comparison of single-bolus tenecteplase and front-loaded alteplase.

  2002cites this paper
• Activated factor XII levels and factor XII 46C>T genotype in relation to coronary artery calcification in patients with type 1 diabetes and healthy subjects.

  2002cites this paper
• Insulin resistance, haemostatic factors and cardiovascular risk

  2002cites this paper
• Rapid factor XII (46C-->T) genotyping by fluorescence resonance energy transfer in patients with coronary artery disease or thrombophilia.

  2001cites this paper
• Rapid Factor XII (46C3 T) Genotyping by Fluorescence Resonance Energy Transfer in Patients with Coronary Artery Disease or Thrombophilia, Matthias Orth, 1* Sabine

  2001cites this paper
• Homozygosity for the C→T polymorphism at nucleotide 46 in the 5′ untranslated region of the factor XII gene protects from development of acute coronary syndrome

  2001cites this paper
• Biomarkers in disease and health

  2001cites this paper
• Effects of Diets Containing Olive Oil, Sunflower Oil, or Rapeseed Oil on the Hemostatic System

  2001cites this paper
• Phosphatidylethanolamine Participates in the Stimulation of the Contact System of Coagulation by Very-Low-Density Lipoproteins

  2001cites this paper
• Experimental Arterial Thrombosis in Genetically or Diet Induced Hyperlipidemia in Rats

  2001cites this paper
• Plasma levels of factor XIIa and factor VIIa are increased but not related in primary hyperlipidaemia

  2001influential citation
• Activated factor XII in rheumatoid arthritis

  2001cites this paper
• A common C-->T polymorphism at nt 46 in the promoter region of coagulation factor XII is associated with decreased factor XII activity.

  2001cites this paper
• Changes in hemostasis during treatment of hypertriglyceridemia with a diet rich in monounsaturated and n-3 polyunsaturated fatty acids in comparison with a low-fat diet.

  2001cites this paper
• Genetic polymorphisms associated with thrombotic disorders in the Japanese population

  2000cites this paper
• Age-dependency in molecular markers of haemostasis, fibrinolysis and in soluble adhesion molecules

  2000cites this paper
• Activated factor XII levels are dependent on factor XII 46C/T genotypes and factor XII zymogen levels, and are associated with vascular risk factors in patients and healthy subjects.

  2000cites this paper
• Functional Abnormality of Anticoagulation Pathway in Thrombotic Patients

  2000cites this paper
• A Monoclonal Antibody Raised against Human β-factor XIIa which also Recognizes α-factor XIIa but not Factor XII or Complexes of Factor XIIa with C1 Esterase Inhibitor

  2000cites this paper
• Fibrinolytic/hemostatic variables in arterial hypertension: response to treatment with irbesartan or atenolol.

  2000cites this paper
• A monoclonal antibody raised against human beta-factor XIIa which also recognizes alpha-factor XIIa but not factor XII or complexes of factor XIIa with C1 esterase inhibitor.

  2000cites this paper
• Factor XIIa and triacylglycerol rich lipoproteins: responses to exercise intervention

  2000cites this paper
• Genotype Distribution of the 46C/T Polymorphism of Coagulation Factor XII in the Japanese Population: Absence of Its Association with Ischemic Cerebrovascular Disease

  2000cites this paper
• Comparison of Novel Hemostatic Factors and Conventional Risk Factors for Prediction of Coronary Heart Disease

  2000cites this paper
• Haemostatic and Lipid Determinants of Prothrombin Fragment F1.2 and D-dimer in Plasma

  2000cites this paper