Nebulizers vs metered-dose inhalers with spacers for bronchodilator therapy to treat wheezing in children aged 2 to 24 months in a pediatric emergency department.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Archives of Pediatrics & Adolescent Medicine

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1001/ARCHPEDI.157.1.76PMID 12517199
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1997cited by this paper
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  1997cited by this paper
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  1996cited by this paper
• A review and economic evaluation of bronchodilator delivery methods in hospitalized patients.

  1996cited by this paper
• Efficacy of bronchodilator therapy in bronchiolitis. A meta-analysis.

  1996cited by this paper
• Metered-dose inhalers with spacers vs nebulizers for pediatric asthma.

  1995cited by this paper
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  1995cited by this paper
• Delivery of salbutamol by metered dose inhaler and valved spacer to wheezy infants: effect on bronchial responsiveness.

  1993cited by this paper
• Efficacy of albuterol administered by nebulizer versus spacer device in children with acute asthma.

  1993cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1991cited by this paper
• Nebulized albuterol in acute bronchiolitis.

  1990cited by this paper
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  1989cited by this paper
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  1987cited by this paper
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  1984cited by this paper

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  2014cites this paper
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