A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Biochemical Journal

• Publication date

  2002-07-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1042/BJ20020450PMID 11978180PMCID PMC1222652
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cloning of the blasticidin S deaminase gene (BSD) from Aspergillus terreus and its use as a selectable marker for Schizosaccharomyces pombe and Pyricularia oryzae

  2004cited by this paper
• Complete genome sequence of Caulobacter crescentus

  2001cited by this paper
• Microbial toxins in plant-pathogen interactions: Biosynthesis, resistance mechanisms, and significance.

  2001cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Molecular markers of serine protease evolution

  2001cited by this paper
• Trichothecene 3-O-Acetyltransferase Protects Both the Producing Organism and Transformed Yeast from Related Mycotoxins

  1998cited by this paper
• Mouse-specific carcinogens: an assessment of hazard and significance for validation of short-term carcinogenicity bioassays in transgenic mice

  1998cited by this paper
• NATURAL OCCURRENCE OF MYCOTOXINS IN FOODS AND FEEDS : AN UPDATED REVIEW

  1998cited by this paper
• Features of Tri101, the trichothecene 3-O-acetyltransferase gene, related to the self-defense mechanism in Fusarium graminearum.

  1998cited by this paper
• Further study on Fusarium mycotoxins in corn and wheat from a high-risk area for human esophageal cancer in China

  1997cited by this paper
• Mycotoxins in Plant Pathogenesis

  1997cited by this paper
• Genotoxicity of zearalenone, an estrogenic mycotoxin: DNA adduct formation in female mouse tissues.

  1995cited by this paper
• Interaction of naturally occurring nonsteroidal estrogens with expressed recombinant human estrogen receptor.

  1994cited by this paper
• Dietary Estrogens Act through Estrogen Receptor-Mediated Processes and Show No Antiestrogenicity in Cultured Breast Cancer Cells.

  1994cited by this paper
• The alpha/beta hydrolase fold.

  1992cited by this paper
• The α/β hydrolase fold

  1992cited by this paper
• High-frequency transformation method and library transducing vectors for cloning mammalian cDNAs by trans-complementation of Schizosaccharomyces pombe.

  1990cited by this paper
• Microbial cleavage of zearalenone.

  1988cited by this paper
• Sequences important for gene expression in filamentous fungi

  1986cited by this paper
• Effects of zearalenone (F2) on estrous activity and reproduction in gilts.

  1982cited by this paper
• Evaluation of the mutagenic potential of mycotoxins using Salmonella typhimurium and Saccharomyces cerevisiae.

  1978cited by this paper
• DNA-attacking ability of carcinogenic mycotoxins in recombination-deficient mutant cells of Bacillus subtilis.

  1976cited by this paper

• A distinct zearalenone detoxification strategy mediated by cytochrome P450.

  2026cites this paper
• Multi-pronged design enhances thermostability of zearalenone hydrolase ZenR for enzymatic detoxification of maize flour.

  2026cites this paper
• Postbiotics as eco-friendly tools: next-generation approaches to mycotoxin mitigation

  2026cites this paper
• Mechanism and Application of Thermostable Superoxide Dismutase from Alcaligenes faecalis HNGD-HTN06 to Degrade AFB1/ZEN.

  2026cites this paper
• Rational Molecular Design for Improved ZHD101 Thermal Stability Based on the Introduction of Disulfide Bonds at the Dimer Interface and B-Factor Analysis.

  2026cites this paper
• Exploring the potent zearalenone-degrading abilities of Bacillus subtilis strain ZEND-1: insights into biodegradation mechanisms and environmental applications.

  2026cites this paper
• Engineering Escherichia coli nissle 1917 with lactonase ZHD101 alleviates zearalenone-induced intestinal disruption and reproductive toxicity in rat

  2025cites this paper
• A Comprehensive Review of Hypotheses About the Biological Function of Zearalenone, and a New Hypothesis for the Function of Resorcylic and Dihydroxyphenylacetic Macrolactones in Fungi

  2025cites this paper
• Biotransformation of Deoxynivalenol to the Novel Metabolite Deoxynivalenol-8,15-hemiketal-7-glucoside by the Bacillus subtilis Glycosyltransferase YjiC

  2025cites this paper
• Microbe-Mediated Removal of Zearalenone Using Yeast Strain Rhodotorula dairenensis Isolated from the Gut Microbiome of Zearalenone-Treated Mice.

  2025cites this paper
• Integrative machine learning and molecular insights into ZEN degradation by Apiotrichum mycotoxinivorans

  2025cites this paper
• Recent advances in zearalenone degradation: integrating physical, chemical, biological, and innovative methods

  2025cites this paper
• Isolation and Characterization of Bacillus velezensis YM1 and its Mechanism for Zearalenone Degradation

  2025cites this paper
• Prevention and detoxification of mycotoxins in food and feed: A review

  2025cites this paper
• Efficient Expression of Lactone Hydrolase Cr2zen for Scalable Zearalenone Degradation in Pichia pastoris

  2025cites this paper
• RmZHD Surface-Displayed Escherichia coli for High Efficiency and Low-Cost Degradation of Zearalenone.

  2025cites this paper
• Green Solutions for Food Safety: The Emerging Applications of Zearalenone-Degrading Enzymes

  2025influential citation
• Insights into the zearalenone degradation performance and pathway by Gordonia hydrophobica HAU421 and characterization of a novel lactonohydrolase involved.

  2025cites this paper
• Biological detoxification and application of emerging control strategies of zearalenone in food.

  2025cites this paper
• Characterization of the Phosphotransferase from Bacillus subtilis 1101 That Is Responsible for the Biotransformation of Zearalenone

  2025cites this paper
• Advances in zearalenone-degrading enzymes research: characteristics, mining, improvement, and application

  2025cites this paper
• Degradation of aflatoxin b1 and zen by recombinant ligninase extracellularly produced from Lactococcus lactis.

  2025cites this paper
• Zearalenone: Contamination, Biological Characterization, and Mechanism of Enzymatic Degradation in Food.

  2025cites this paper
• A Priestia megaterium MF3 with high-efficiency zearalenone degradation: functional genomic insights and mechanistic exploration

  2025cites this paper
• Detoxification of mycotoxins by microorganisms.

  2025cites this paper
• Enzymatic detoxification of major mycotoxins: current status, challenges, and future prospective

  2025influential citation
• Substrate specificity study of zearalenone lactonase by analyzing interaction networks of residues near the β6-α6 region.

  2024cites this paper
• Enzymatic Hydrolysis of Resorcylic Acid Lactones by an Aeromicrobium sp.

  2024cites this paper
• Opportunities and challenges in developing promising mycotoxin-degrading enzymes with high thermostability and strong pH activity/stability

  2024cites this paper
• Bacterial Lactonases ZenA with Noncanonical Structural Features Hydrolyze the Mycotoxin Zearalenone

  2024cites this paper
• Simultaneous Degradation of AFB1 and ZEN by CotA Laccase from Bacillus subtilis ZJ-2019-1 in the Mediator-Assisted or Immobilization System

  2024cites this paper
• Characterization, Structural Analysis, and Thermal Stability Mutation of a New Zearalenone-Degrading Enzyme Mined from Bacillus subtilis.

  2024cites this paper
• A novel glycosyltransferase from Bacillus subtilis achieves zearalenone detoxification by diglycosylation modification.

  2024cites this paper
• Review: Strategies and technologies in preventing regulated and emerging mycotoxin co-contamination in forage for safeguarding ruminant health.

  2024cites this paper
• A new physical and biological strategy to reduce the content of zearalenone in infected wheat kernels: the effect of cold needle perforation, microorganisms, and purified enzyme.

  2024cites this paper
• The Protein Engineering of Zearalenone Hydrolase Results in a Shift in the pH Optimum of the Relative Activity of the Enzyme

  2024cites this paper
• Bioenzymatic detoxification of mycotoxins

  2024cites this paper
• Enhancing the activity of zearalenone lactone hydrolase toward the more toxic α-zearalanol via a single-point mutation

  2024cites this paper
• Biochemical Characterization and Application of Zearalenone Lactone Hydrolase Fused with a Multifunctional Short Peptide.

  2024cites this paper
• Enzymatic characterization and application of soybean hull peroxidase as an efficient and renewable biocatalyst for degradation of zearalenone.

  2024cites this paper
• Biotransformation of zearalenone to non-estrogenic compounds with two novel recombinant lactonases from Gliocladium

  2024influential citation
• A Sustainable Approach for Degradation of Alternariol by Peroxidase Extracted from Soybean Hulls: Performance, Pathway, and Toxicity Evaluation

  2024cites this paper
• Enhancing the thermal stability and activity of zearalenone lactone hydrolase to promote zearalenone degradation via semi-rational design.

  2024cites this paper
• Patulin-degrading enzymes sources, structures, and mechanisms: A review.

  2024cites this paper
• Application of luminescent Photobacterium Phosphoreum T3 for the detection of zearalenone and estimating the efficiency of their enzymatic degradation

  2024cites this paper
• Biodegradation of patulin in fresh pear juice by an aldo-keto reductase from Meyerozyma guilliermondii.

  2023cites this paper
• Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review

  2023cites this paper
• The N-terminal hydrophobicity modulates a distal structural domain conformation of zearalenone lacton hydrolase and its application in protein engineering.

  2023cites this paper
• Biochemical characterization and molecular modification of a zearalenone hydrolyzing enzyme Zhd11D from Phialophora attinorum.

  2023cites this paper
• Containment of Fusarium culmorum and Its Mycotoxins in Various Biological Systems by Antagonistic Trichoderma and Clonostachys Strains

  2023cites this paper
• Effective degradation of zearalenone by dye-decolorizing peroxidases from Pleurotus ostreatus and its metabolic pathway and toxicity analysis.

  2023cites this paper
• Mutation, food-grade expression, and characterization of a lactonase for zearalenone degradation

  2023influential citation
• A Hydrolase Produced by Rhodococcus erythropolis HQ Is Responsible for the Detoxification of Zearalenone

  2023cites this paper
• A Probiotic Bacillus amyloliquefaciens D-1 Strain Is Responsible for Zearalenone Detoxifying in Coix Semen

  2023cites this paper
• Mycotoxin Contamination Status of Cereals in China and Potential Microbial Decontamination Methods

  2023cites this paper
• Post-Harvest Prevention of Fusariotoxin Contamination of Agricultural Products by Irreversible Microbial Biotransformation: Current Status and Prospects

  2023cites this paper
• Simultaneous degradation of aflatoxin B1 and zearalenone by Porin and Peroxiredoxin enzymes cloned from Acinetobacter nosocomialis Y1.

  2023cites this paper
• An overview of chemical, physical and biological methods for zearalenone elimination: Recent advances and future prospective

  2023cites this paper
• Purification and characterization of the enzymes from Brevundimonas naejangsanensis that degrade ochratoxin A and B.

  2023cites this paper
• Identification and Modification of Enzymatic Substrate Specificity through Residue Alteration in the Cap Domain: A Thermostable Zearalenone Lactonase.

  2023cites this paper
• New Hydrolase from Aeromicrobium sp. HA for the Biodegradation of Zearalenone: Identification, Mechanism, and Application.

  2023cites this paper
• Recent developments of mycotoxin-degrading enzymes: identification, preparation and application

  2023cites this paper
• Isolation, Characterization, and Application of Clostridium sporogenes F39 to Degrade Zearalenone under Anaerobic Conditions

  2022cites this paper
• Removal of Zearalenone from Degummed Corn Oil by Hydrolase on a Batch-Refining Unit

  2022cites this paper
• Detoxification approaches of mycotoxins: by microorganisms, biofilms and enzymes

  2022cites this paper
• Excavation, expression, and functional analysis of a novel zearalenone-degrading enzyme

  2022cites this paper
• Biocatalysis of heterogenously-expressed d-lactonohydrolases and its efficient preparation of desirable d-pantoic acid.

  2022cites this paper
• Microbial Enzymes Involved in the Biotransformation of Major Mycotoxins.

  2022cites this paper
• Kinetics, Thermodynamics and Mechanism of Enzymatic Degradation of Zearalenone in Degummed Corn Oil

  2022influential citation
• Cloning and Characterization of Three Novel Enzymes Responsible for the Detoxification of Zearalenone

  2022cites this paper
• Detoxification of ochratoxin A and zearalenone by Pleurotus ostreatus during in vitro gastrointestinal digestion.

  2022cites this paper
• Microbial detoxification of mycotoxins in food

  2022cites this paper
• Zearalenone lactonase: characteristics, modification, and application

  2022cites this paper
• Isolation and Mechanistic Characterization of a Novel Zearalenone-Degrading Enzyme

  2022influential citation
• Detoxification of the mycoestrogen zearalenone by Bacillus licheniformis spore CotA laccase and application of immobilized laccase in contaminated corn meal

  2022cites this paper
• The control of Fusarium growth and decontamination of produced mycotoxins by lactic acid bacteria

  2022cites this paper
• Combined in silico investigation and in vitro characterization of the zearalenone detoxification potential of dye-decolorizing peroxidase from Bacillus subtilis 168

  2022cites this paper
• Shinella oryzae sp. nov., a novel zearalenone-resistant bacterium isolated from rice paddy soil

  2022cites this paper
• Enzymatic Degradation of Multiple Major Mycotoxins by Dye-Decolorizing Peroxidase from Bacillus subtilis

  2021cites this paper
• New Biotransformation Mode of Zearalenone Identified in Bacillus subtilis Y816 Revealing a Novel ZEN Conjugate.

  2021cites this paper
• Recombinant expression and surface display of a zearalenone lactonohydrolase from Trichoderma aggressivum in Escherichia coli.

  2021cites this paper
• Key Global Actions for Mycotoxin Management in Wheat and Other Small Grains

  2021cites this paper
• Microbial detoxification of mycotoxins in food and feed

  2021cites this paper
• The Improved Expression and Stability of Zearalenone Lactonohydrolase from Escherichia coli BL21 (DE3)

  2021cites this paper
• Clonostachys rosea to control plant diseases

  2021cites this paper
• In Vitro Mechanism Assessment of Zearalenone Removal by Plant-Derived Lactobacillus plantarum BCC 47723

  2021cites this paper
• Recent advances in detoxification strategies for zearalenone contamination in food and feed

  2020cites this paper
• Review on microbial degradation of zearalenone and aflatoxins

  2020cites this paper
• Whole-Genome Sequencing and Bioinformatics Analysis of Apiotrichum mycotoxinivorans: Predicting Putative Zearalenone-Degradation Enzymes

  2020cites this paper
• Effective Zearalenone Degradation in Model Solutions and Infected Wheat Grain Using a Novel Heterologous Lactonohydrolase Secreted by Recombinant Penicillium canescens

  2020cites this paper
• Zearalenone Removal from Corn Oil by an Enzymatic Strategy

  2020cites this paper
• Identification of a Bacillus amyloliquefaciens H6 thioesterase involved in zearalenone detoxification by transcriptomic analysis.

  2020cites this paper
• Biodetoxification of fungal mycotoxins zearalenone by engineered probiotic bacterium Lactobacillus reuteri with surface-displayed lactonohydrolase

  2019cites this paper
• 12: Mycotoxins in the feed and animal products

  2019cites this paper
• Enzyme Technology for Detoxification of Mycotoxins in Animal Feed

  2019cites this paper
• Biocatalytic transformation of various mycotoxins: modern problems and existing potential

  2019cites this paper
• Detoxification Strategies for Zearalenone Using Microorganisms: A Review

  2019cites this paper
• Degrading Ochratoxin A and Zearalenone Mycotoxins Using a Multifunctional Recombinant Enzyme

  2019cites this paper
• Tox n B nders Used n Anımal Nutr t on

  2019cites this paper
• Enzymes for Degradation of Fusarium Mycotoxins

  2019cites this paper