Relaxing the rule of ten events per variable in logistic and Cox regression.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  American Journal of Epidemiology

• Publication date

  2007-03-15

• Fields of study

  Mathematics, Medicine

• Identifiers
  DOI 10.1093/AJE/KWK052PMID 17182981
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Prognostic/Clinical Prediction Models: Multivariable Prognostic Models: Issues in Developing Models, Evaluating Assumptions and Adequacy, and Measuring and Reducing Errors

  2005cited by this paper
• A simulation study of the number of events per variable in logistic regression analysis.

  1996cited by this paper
• Importance of events per independent variable in proportional hazards regression analysis. II. Accuracy and precision of regression estimates.

  1995cited by this paper
• Importance of events per independent variable in proportional hazards analysis. I. Background, goals, and general strategy.

  1995cited by this paper
• Modeling and variable selection in epidemiologic analysis.

  1989cited by this paper
• Veterans Administration Cooperative Study of medical versus surgical treatment for stable angina--progress report. Section 2. Design and baseline characteristics.

  1985cited by this paper
• Section 2 Design and baseline characteristics

  1985cited by this paper
• Veterans Administration Cooperative Study of medical versus surgical treatment for stable angina--progress report. Section 4. Long-term survival results in medically and surgically randomized patients.

  1985cited by this paper
• Sample-size formula for the proportional-hazards regression model.

  1983cited by this paper

• Combined plasma syndecan-1 and renal resistive index as early predictors of sepsis-associated Acute kidney injury: a prospective observational study.

  2026cites this paper
• Impact of a participatory research intervention based on a citizen science approach on snacking consumption in European adolescents from deprived areas: a cluster randomised control trial of the SEEDS project.

  2026cites this paper
• Independent Risk Factors for Sacral Fracture After Lumbosacral Fusion in Adults: A Cox Proportional Hazards Retrospective Analysis.

  2026cites this paper
• Predictors of the early discontinuation of anamorelin hydrochloride in gastrointestinal cancer-related cachexia: a multicenter retrospective cohort study (HGCSG2201)

  2026cites this paper
• The proportion, clinical predictors, and prognostic impact of hypometabolic estrogen receptor-positive primary breast cancer on baseline [18F] fluorodeoxyglucose PET.

  2026cites this paper
• Risk-stratified surveillance after LEEP: a nomogram integrating HPV persistence, margin status, and clinical factors to predict CIN2+ recurrence

  2026cites this paper
• Minding the knowledge-action gap: Results from a mixed-methods study of antimicrobial use among dairy farmers in central Uganda

  2026cites this paper
• Between competences and fear of failure: empirical evidence on the profile of the nascent entrepreneur

  2026cites this paper
• Interatrial Block in Hypertrophic Cardiomyopathy: Associations With Left Atrial Remodeling and Adverse Atrial Outcomes.

  2026cites this paper
• Barriers students with epilepsy and their caregivers face regarding school participation and seizure management within school.

  2026cites this paper
• Analysis of medication adherence and influencing factors in postpartum patients with persistent hyperglycemia following gestational diabetes mellitus.

  2026cites this paper
• Impact of sleep disturbances on post-intensive care syndrome-cognitive impairment in intensive care unit survivors: A prospective cohort study.

  2026cites this paper
• Sample Size Calculations for Developing Clinical Prediction Models: Overview and pmsims R package

  2026cites this paper
• Household determinants of food security among leafy vegetable producers in semi-arid central Tanzania

  2026cites this paper
• Environmental enteric dysfunction in well-nourished and undernourished women in Bangladesh

  2026cites this paper
• Early Predictors of Necrosis in Patients Presenting With Edematous Acute Pancreatitis: Prospective Validation of the Necrosis Development Score-48 (NDS-48).

  2026cites this paper
• Identification and validation of an interpretable EEG-based machine learning model for the diagnosis of post-stroke cognitive impairment

  2026cites this paper
• A nomogram for predicting sedation-related adverse events in elderly patients undergoing painless gastrointestinal endoscopy

  2026cites this paper
• Psychological and Demographic Drivers of Embedded EV Insurance Adoption in Taiwan, China

  2026cites this paper
• The interplay between firm innovation, digital capabilities and HR skills and practices: The moderating role of GVC participation

  2026cites this paper
• Noninvasive assessment of right ventricular-pulmonary artery coupling may predict acute kidney injury after primary PCI in STEMI patients.

  2026cites this paper
• Helicobacter pylori Colonization and Intestinal Metaplasia Risk in an Andean Population: A Cross-Sectional Study from Peru

  2026cites this paper
• Effects of graphical representations on teachers’ interpretation of learning progress data. A registered replication

  2026cites this paper
• A Quantitative Chinese Medicine-Derived Dampness Score, Heart Failure Staging, and 12-Month Major Adverse Cardiovascular Events: A Prospective Cohort Study.

  2026cites this paper
• Prediction models for early neurological deterioration in patients with acute ischemic stroke: a systematic review and critical appraisal

  2026cites this paper
• Layered vulnerabilities in young adults with major depressive disorder: personality, coping, and cognition

  2026cites this paper
• Methodological considerations in “Frequency of and factors associated with social problems among working-age patients with cancer in Japan”

  2026cites this paper
• Association of anemia with long-term renal prognosis in autosomal dominant polycystic kidney disease using time-series analysis.

  2026cites this paper
• Predictors of Mortality Among Pediatric Patients Admitted to Intensive Care Units in Eastern Amhara, Ethiopia: A Prospective Multi-Center Cohort Study.

  2026cites this paper
• The role of cytokines in acute gastrointestinal injury: a prospective pilot study

  2026cites this paper
• Re-anchored lives: Working from home, gender, and everyday well-being in Sweden

  2026cites this paper
• Risk factors and clinical outcomes associated with leptomeningeal carcinomatosis in gastric cancer

  2026cites this paper
• Clinical impact of disease stability on exacerbation and mortality in COPD: a retrospective cohort study

  2026cites this paper
• Left atrioventricular coupling index and atrial fibrillation and stroke in hypertrophic cardiomyopathy: a CMR study.

  2026cites this paper
• Postoperative prognostic factors for inability to walk at 6 weeks after fragility hip fracture surgery: A retrospective cohort study

  2026influential citation
• Beyond poverty, tungiasis is associated with family characteristics and parenting behavior: a case control study in Kenya

  2026cites this paper
• Survival predictors in Vietnamese elderly AML patients treated with decitabine: Real-world evidence from a low- and middle-income country

  2026cites this paper
• Differential impacts of stuttering and stressful life events on the well-being of children: A comparative analysis.

  2026cites this paper
• Aberrant methylation limits antitumoral inflammation in lung adenocarcinoma by restricting RIPK3 expression.

  2026cites this paper
• Age-specific vaginal microecological dysbiosis associated with HPV infection: a large-scale cross-sectional study with targeted functional sequencing validation

  2026cites this paper
• The establishment of dynamic microexpression training tool

  2026cites this paper
• Delivery timelines and determinants of assistive technology for mobility and participation in paediatric rehabilitation: a retrospective cohort study.

  2026cites this paper
• Echocardiographic features and prognostic implications in acute type a intramural hematoma and classic aortic dissection.

  2026cites this paper
• Enhanced Efficacy of Rotational Atherectomy for Calcified Nodules With Contralateral Calcification: Insights From a Multicenter Intravascular Ultrasound Imaging Study.

  2026cites this paper
• Gender-Specific Correlates of Suicidal Behaviour: Insights from the Interpersonal Theory of Suicide.

  2026cites this paper
• Cox Regression in Survival Analysis: Practical Insights for Clinicians.

  2026cites this paper
• Does telehealth use impact clinical outcomes during a multi-disciplinary pain management program?

  2026cites this paper
• Exploratory Analysis of Factors Affecting 30-Day, 90-Day, and 1-Year Readmission After Surgical Treatment of Primary Spinal Infection in Adults.

  2026cites this paper
• Matters arising: statistical overfitting and outcome discordance undermine the claimed superiority of T2 fusion for shoulder balance in adolescent idiopathic scoliosis

  2026cites this paper
• A Comparison of Virtual Reality and Traditional Measures of Memory in the Diagnostic Discriminability of Neurocognitive Disorders: A Virtual Kitchen Protocol Study.

  2026cites this paper
• Factors associated with hospitalization or surgery for abdominal pain: a retrospective study.

  2026cites this paper
• Short Against Long Antibiotic Therapy for Infected Orthopaedic Sites—2nd Interim Analysis of the SALATIO Trials

  2026cites this paper
• Explainable machine learning versus logistic regression for outcome prediction in primary intracerebral hemorrhage: A multicenter radiomics study

  2026cites this paper
• Topical Hemostatic Agents and the Risk of Pelvic Infection in Gynecologic Surgery.

  2026cites this paper
• Perioperative trajectories of acute-phase proteins and their association with major postoperative complications in advanced ovarian cancer.

  2026cites this paper
• Predictors of 90-Days Readmission and Emergency Visits Following Catheter Ablation for Arrhythmias: A Retrospective Study.

  2026influential citation
• The association between inflammatory indices and acute pancreatitis severity: a retrospective cohort study

  2026cites this paper
• Methodological considerations and clinical implications of pain assessment in rare bone diseases.

  2026cites this paper
• Ventilator-associated pneumonia in adult ICU patients with epidermal necrolysis: A retrospective cohort study from the French National Referrence Centre.

  2026cites this paper
• Nephrotoxicity Risk Assessment of Liposomal Amphotericin B in Hematology–Oncology Patients: A Real-World Study From Saudi Arabia

  2026cites this paper
• Food insecurity and associated factors among adult cancer patients in south Ethiopia: a cross-sectional study.

  2026cites this paper
• Investigating the Radiomic Performance Gap Driven by Delineation Strategy: Radiotherapy Gross Tumor Volume vs. Dedicated Lesion Segmentation in Proton-Treated Adenoid Cystic Carcinoma

  2026cites this paper
• Statistical methodological limitations and improvement suggestions in the study of vitamin D deficiency and cardiovascular mortality after heart transplantation.

  2026cites this paper
• Effects of tree size, crown damage and wood density on hollow trunk occurrence in Amazonian timber species

  2026cites this paper
• Response to letter to the editor regarding "Nailfold Capillaroscopy as a predictor of cardiovascular events and mortality in systemic sclerosis".

  2026cites this paper
• Integration of patient-reported outcomes and myokine profiling for the detection of physical inactivity in COPD: an exploratory multicentre study

  2026cites this paper
• Agricultural landscapes dominated by non-pollinator-dependent crops may play a role on the conservation of wild bees in riparian areas

  2026cites this paper
• Contemporary Assessment of Post-Operative Pancreatic Fistula After Pancreatoduodenectomy in a European Hepato-Pancreato-Biliary Center: A 5-Year Experience

  2026cites this paper
• Impact of Visual Magnification on MB2 Canal Detection in a Laboratory-Based Study Using Standardized 3D-Printed Maxillary Molars

  2026cites this paper
• Candidate prognostic factors of presenteeism among French workers: an exploratory longitudinal study

  2026cites this paper
• The long-term outcomes of maxillary implant-supported overdentures: A retrospective study.

  2026cites this paper
• Rates and predictors of postdischarge opioid-free analgesia after elective colorectal surgery: A prospective cohort study.

  2026cites this paper
• Risk-Stratified Predictive Analysis of Docking Site Outcomes in Lower Extremity Bone Transport: Identifying High-Risk and Low-Risk Zones for Large Segmental Defect Management

  2026cites this paper
• Is Latin America a Region for Green Parties? Factors Behind Their Presence and Performance

  2026cites this paper
• Predictors of Delayed Graft Function in Living and Deceased Donor Kidney Transplantation: A Single-Centre Retrospective Cohort Study from India

  2026cites this paper
• Suicidality in the Criminal Justice System: The Role of Cumulative Adversity and Protective Factors

  2026cites this paper
• Prevalence and Socio-Behavioural Determinants of Periodontal Disease Among Adults in the Northern West Bank: A Cross-Sectional Study

  2026cites this paper
• Combined association between dietary inflammatory index-related dietary patterns and physical activity with frailty in Chinese older adults: findings from a cross-sectional

  2026cites this paper
• Prognostic Value of Atrial Phasic Dysfunction by CMR Feature Tracking for New-Onset Atrial Fibrillation in Patients with Cardiac Sarcoidosis

  2026cites this paper
• Digital tomosynthesis derived textural and geometric measures of vertebral bone quality in postmenopausal women with primary hyperparathyroidism.

  2026cites this paper
• Prevalence, Clinical Correlates, Gender Differences, and Predictive Factors of Paradoxical Insomnia in Chinese Adults with Chronic Insomnia: A Cross-Sectional Study

  2026cites this paper
• Social Pressure to Reduce Alcohol Drinking and Mortality 20 years Later in a General Population Sample: A Cohort Study

  2026cites this paper
• Sit-to-Stand Navicular Drop Test-Based Injury Risk Zones Derived from a U-Shaped Relationship in Male University Athletes

  2026cites this paper
• Prognostic value of RecurIndex in differentiating HER2-low from HER2-negative early-stage breast cancer: a comprehensive clinicopathologic and molecular analysis in Chinese patients

  2026cites this paper
• BMI subclassification and future risk of metabolic dysfunction-associated steatotic liver disease and liver-related events.

  2026cites this paper
• Trends, Predictors, and Outcomes of Monitored Acute Care Unit Admissions in Older Adults: 10-Year Retrospective Analysis

  2026cites this paper
• Development and validation of an interpretable machine learning model for predicting the risk of 8-year all-cause mortality in Cardiovascular-Kidney-Metabolic Syndrome among older adults: A multicenter and cohort study

  2026cites this paper
• Paroxysmal Atrial Fibrillation in Liver Diseases: Epidemiology and Possible Pathophysiological Mechanisms

  2026cites this paper
• Comments on "Severe bleeding in patients following "tubeless" percutaneous nephrolithotomy: Predictors of angioembolization".

  2026cites this paper
• Essentialist Beliefs About Sexual Orientation: Co-Occurrence, Associated Factors, and Relationship with Sexual Prejudice Attitudes.

  2026cites this paper
• Development and testing of a prognostic scoring system for screw-positioning related femoral neck fracture failures for younger adults

  2026cites this paper
• All-cause and cause-specific mortality among transgender and gender diverse people: a nationwide cohort study in Australia.

  2026cites this paper
• Impact of syncope history on long-term physical activity in patients ≥2 years after transcatheter aortic valve replacement: a single-centre cross-sectional study in China

  2026cites this paper
• An 18F-FDG PET/CT-based radiomics nomogram for predicting progression-free survival in nasopharyngeal carcinoma: A retrospective cohort study

  2026cites this paper
• Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry.

  2026cites this paper
• Machine learning-based predictive model for post-stroke cardiorespiratory fitness.

  2026cites this paper
• From Branch to Digital: Modeling Customer Channel Preferences in Electronic Banking Services

  2026cites this paper
• Reliability of airway occlusion pressure (P0.1) in predicting extubation failure in critically ill patients

  2026cites this paper
• Comments on "Stage-Specific Predictors and Outcomes of Colistin-Associated Acute Kidney Injury in Surgical and Medical ICU Patients".

  2026cites this paper
• Revisiting subclavian access in the ultrasound era: are we comparing sites or techniques? Author's reply.

  2026cites this paper