Potent in vitro and in vivo inhibitors of platelet aggregation based upon the Arg-Gly-Asp-Phe sequence of fibrinogen. A proposal on the nature of the binding interaction between the Arg-guanidine of RGDX mimetics and the platelet GP IIb-IIIa receptor.

J. Zablocki,M. Miyano,R. B. Garland,D. Pireh,L. Schretzman,S. N. Rao,R. Lindmark,S. Panzer-Knodle,N. Nicholson,B. Taite

Published 1993 in Journal of Medicinal Chemistry

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