Neutrophil superoxide anion--generating capacity, endothelial function and oxidative stress in chronic heart failure: effects of short- and long-term vitamin C therapy.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of the American College of Cardiology

• Publication date

  2000-11-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1016/S0735-1097(00)00916-5PMID 11079645
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Uptake of ascorbic acid by human neutrophils.

  2009cited by this paper
• Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure.

  2000cited by this paper
• Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus.

  2000cited by this paper
• Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease.

  1999cited by this paper
• l-Ascorbic Acid Potentiates Nitric Oxide Synthesis in Endothelial Cells*

  1999cited by this paper
• Increased Oxidative Stress in Patients With Congestive Heart Failure

  1998cited by this paper
• Vitamin C improves endothelial function of conduit arteries in patients with chronic heart failure.

  1998influential reference
• Increased oxidative stress in patients with congestive heart failure.

  1998cited by this paper
• Ascorbate-dependent enhancement of nitric oxide formation in activated macrophages.

  1998cited by this paper
• Elevation of an endogenous inhibitor of nitric oxide synthesis in experimental congestive heart failure.

  1998cited by this paper
• Nitric oxide inhibition of lipid peroxidation: kinetics of reaction with lipid peroxyl radicals and comparison with alpha-tocopherol.

  1997cited by this paper
• The epidemiology of heart failure.

  1997cited by this paper
• Mechanisms of exercise limitation in chronic heart failure and the role of rehabilitation.

  1997cited by this paper
• Vitamins C and E inhibit O2- production in the pig coronary artery.

  1997cited by this paper
• Cellular and molecular mechanisms of endothelial cell dysfunction.

  1997cited by this paper
• Mechanisms and implications of endothelial dysfunction in congestive heart failure.

  1997cited by this paper
• Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

  1996cited by this paper
• Endothelial control of arterial distensibility is impaired in chronic heart failure.

  1995cited by this paper
• Oxidative stress and heart failure

  1995cited by this paper
• Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice.

  1994cited by this paper
• Rapid, sensitive, and specific thiobarbituric acid method for measuring lipid peroxidation in animal tissue, food, and feedstuff samples

  1994cited by this paper
• Cellular localization and regional distribution of an angiotensin II-forming chymase in the heart.

  1993cited by this paper
• The epidemiology of heart failure: the Framingham Study.

  1993cited by this paper
• Elevated breath pentane in heart failure reduced by free radical scavenger.

  1993cited by this paper
• Evidence of oxidative stress in chronic heart failure in humans.

  1993cited by this paper
• Hypercholesterolemia increases endothelial superoxide anion production.

  1993cited by this paper
• Biochemistry of nitric oxide and its redox-activated forms.

  1992cited by this paper
• Rates of interactions of superoxide with vitamin E, vitamin C and related compounds as measured by chemiluminescence.

  1992cited by this paper
• Oxygen free radicals and congestive heart failure.

  1991cited by this paper
• Nitric oxide production by cultured aortic endothelial cells in response to thiol depletion and replenishment.

  1991cited by this paper
• ESR methods : an ESR and ENDOR study of biological systems using the technique of spin trapping and spin labelling

  1990cited by this paper
• Ascorbate: the most effective antioxidant in human blood plasma.

  1990cited by this paper
• Elevated circulating levels of tumor necrosis factor in severe chronic heart failure.

  1990cited by this paper
• Deleterious Effects of Oxygen Radicals in Ischemia/Reperfusion Resolved and Unresolved Issues

  1989cited by this paper
• Evidence of direct toxic effects of free radicals on the myocardium.

  1988cited by this paper
• Spin trapping: ESR parameters of spin adducts.

  1988cited by this paper
• Lucigenin chemiluminescence in the assessment of neutrophil superoxide production.

  1987cited by this paper
• A highly sensitive high-performance liquid chromatography method for the estimation of ascorbic and dehydroascorbic acid in tissues, biological fluids, and foods.

  1987cited by this paper
• Increased superoxide anion release from human endothelial cells in response to cytokines.

  1986cited by this paper
• The antioxidant role of vitamin C

  1986cited by this paper
• [Patients with congestive heart failure. 1].

  1985cited by this paper
• Hydrogen peroxide and hydroxyl radical mediation of activated leukocyte depression of cardiac sarcoplasmic reticulum. Participation of the cyclooxygenase pathway.

  1983cited by this paper
• Direct observation of a free radical interaction between vitamin E and vitamin C

  1979cited by this paper

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  2021cites this paper
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  2020cites this paper
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  2020influential citation
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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