Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Molecular and Cellular Biology

• Publication date

  1994-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.14.3.1669PMID 8114703PMCID PMC358525
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes.

  1993cited by this paper
• Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts.

  1993cited by this paper
• Mammalian G1 cyclins.

  1993cited by this paper
• Cyclin-dependent regulation of G1 in mammalian fibroblasts.

  1993cited by this paper
• Cyclins and cyclin-dependent kinases: take your partners.

  1993cited by this paper
• Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15.

  1993cited by this paper
• A Drosophila G1-specific cyclin E homolog exhibits different modes of expression during embryogenesis.

  1993cited by this paper
• Redundant cyclin overexpression and gene amplification in breast cancer cells.

  1993cited by this paper
• Control of the yeast cell cycle by the Cdc28 protein kinase.

  1993cited by this paper
• Cyclin E and cyclin A as candidates for the restriction point protein.

  1993cited by this paper
• The cdk2 kinase is required for the G1-to-S transition in mammalian cells.

  1993cited by this paper
• Independent regulation of human D-type cyclin gene expression during G1 phase in primary human T lymphocytes.

  1993cited by this paper
• Cyclin D1 is a nuclear protein required for cell cycle progression in G1.

  1993cited by this paper
• Animal cell cycles and their control.

  1992cited by this paper
• Suppression of growth factor-induced CYL1 cyclin gene expression by antiproliferative agents.

  1992cited by this paper
• Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts.

  1992cited by this paper
• A proliferation of cyclins.

  1992cited by this paper
• Association of human cyclin E with a periodic G1-S phase protein kinase.

  1992cited by this paper
• Identification and cloning of two overexpressed genes, U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas.

  1992cited by this paper
• Cell cycle control in normal and neoplastic cells.

  1992cited by this paper
• Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle.

  1992cited by this paper
• The role of p34 kinases in the G1 to S-phase transition.

  1992cited by this paper
• Regulation of retinoblastoma protein functions by ectopic expression of human cyclins.

  1992cited by this paper
• Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.

  1992cited by this paper
• Gene rearrangement and overexpression of PRAD1 in lymphoid malignancy with t(11;14)(q13;q32) translocation.

  1992cited by this paper
• Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

  1992cited by this paper
• Cyclin A is required in S phase in normal epithelial cells.

  1992cited by this paper
• A family of human cdc2‐related protein kinases.

  1992cited by this paper
• Different G1 cyclins control the timing of cell cycle commitment in mother and daughter cells of the budding yeast S. cerevisiae.

  1992cited by this paper
• Cyclin A is required at two points in the human cell cycle.

  1992cited by this paper
• Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

  1992cited by this paper
• D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1.

  1991cited by this paper
• Characterization of a candidate bcl-1 gene

  1991cited by this paper
• Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast.

  1991cited by this paper
• G1-specific cyclins: in search of an S-phase-promoting factor.

  1991cited by this paper
• Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle.

  1991cited by this paper
• Population explosion in the cyclin family.

  1991cited by this paper
• Cyclin-dependent kinases: a new cell cycle motif?

  1991cited by this paper
• Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.

  1991cited by this paper
• A novel cyclin encoded by a bcl1-linked candidate oncogene

  1991cited by this paper
• Human D-type cyclin.

  1991cited by this paper
• Cyclin A is required for the onset of DNA replication in mammalian fibroblasts.

  1991cited by this paper
• G1-specific cyclins of S. cerevisiae: cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase.

  1990cited by this paper
• p34cdc2: the S and M kinase?

  1990cited by this paper
• Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B

  1990cited by this paper
• A family of cyclin homologs that control the G1 phase in yeast.

  1989cited by this paper
• Maturation promoting factor, cyclin and the control of M-phase.

  1989cited by this paper
• G1 events and regulation of cell proliferation.

  1989cited by this paper
• The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog.

  1988cited by this paper
• DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae

  1988cited by this paper

• A Novel COL12A1 Mutation Causes Oral Tissue Abnormalities by Regulating Gingival Fibroblast Function.

  2025cites this paper
• Big1 is a cell cycle regulator linking cell size to basal body number

  2025cites this paper
• Targeting CDK4 and CDK6 in hormone-dependent cancers.

  2025cites this paper
• Targeting the MCM10/p53/p21/CCND1 Axis in Colorectal Cancer: Evaluating the Therapeutic Potential of Ultrasound.

  2025cites this paper
• The advances in acetylation modification in senescence and aging-related diseases

  2025cites this paper
• MEIOC prevents continued mitotic cycling and promotes meiotic entry during mouse oogenesis

  2025cites this paper
• PAK4 phosphorylates cyclin-dependent kinase 2 to promote the G1/S transition during adipogenesis

  2025cites this paper
• Anti-cancer effect of sodium pentaborate in combination with cisplatin on lung cancer cell lines

  2024cites this paper
• Genetic Characteristics of the Rat Fibroblast Cell Line Rat-1

  2024cites this paper
• APC/C prevents a noncanonical order of cyclin/CDK activity to maintain CDK4/6 inhibitor–induced arrest

  2024cites this paper
• NMDA receptor-mediated Ca2+ signaling: Impact on cell cycle regulation and the development of neurodegenerative diseases and cancer.

  2024cites this paper
• USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination

  2024cites this paper
• Tolerance of Oncogene-Induced Replication Stress: A Fuel for Genomic Instability

  2024cites this paper
• G1 Dynamics at the Crossroads of Pluripotency and Cancer

  2023cites this paper
• An anti-cancer surveillance by the interplay between interferon-beta and retinoblastoma protein RB1

  2023cites this paper
• The Adenylyl Cyclase Activator Forskolin Increases Influenza Virus Propagation in MDCK Cells by Regulating ERK1/2 Activity

  2023cites this paper
• APC/C prevents non-canonical order of cyclin/CDK activity to maintain CDK4/6 inhibitor-induced arrest

  2023cites this paper
• Effects of the tumor necrosis factor on hemocyte proliferation and bacterial infection in Chinese mitten crab (Eriocheir sinensis).

  2023cites this paper
• Cell cycle dysregulation on prenatal and postnatal arsenic exposure in skin of Wistar rat neonates

  2023cites this paper
• Comparative Genomic Analysis of the Thiolase Family and Functional Characterization of the Acetyl-Coenzyme A Acyltransferase-1 Gene for Milk Biosynthesis and Production of Buffalo and Cattle.

  2023cites this paper
• Disruption of cell division prevents gametogenesis in triploid Pacific oysters (Crassostrea gigas)

  2022cites this paper
• Identification and functional characterization of Pomstna in Japanese flounder (Paralichthys olivaceus).

  2022cites this paper
• Molecular Patho-mechanisms of cervical cancer (MMP1)

  2022cites this paper
• An Affordable Approach of Mesenchymal Stem Cell Therapy in Treating Perianal Fistula Treatment.

  2022cites this paper
• The consequences of differential origin licensing dynamics in distinct chromatin environments

  2022cites this paper
• BAP18 induces growth of non-small-cell lung carcinoma through upregulating transcriptional level of CCND1/2.

  2022cites this paper
• Gene identification and functional analysis of a D-type cyclin (CCND2) in freshwater pearl mussel (Hyriopsis cumingii)

  2022cites this paper
• Differentiation Capacity of Bone Marrow-Derived Rat Mesenchymal Stem Cells from DsRed and Cre Transgenic Cre/loxP Models

  2022cites this paper
• FAK in the nucleus prevents VSMC proliferation by promoting p27 and p21 expression via Skp2 degradation.

  2021cites this paper
• Pharmacological relevance of CDK inhibitors in Alzheimer's disease.

  2021cites this paper
• Ferric ammonium citrate (FAC)-induced inhibition of osteoblast proliferation/differentiation and its reversal by soybean-derived peptides (SDP).

  2021cites this paper
• Cyclin E/CDK2: DNA Replication, Replication Stress and Genomic Instability

  2021cites this paper
• Current Knowledge in Genetics, Molecular Diagnostic Tools, and Treatments for Mantle Cell Lymphomas

  2021cites this paper
• A systematic review and meta-analysis

  2021cites this paper
• A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells

  2021cites this paper
• Clinicopathological and prognostic significance of circRNAs in lung cancer

  2021cites this paper
• Quantitative profiling of adaptation to cyclin E overproduction

  2021cites this paper
• Temporal Changes In Cyclin D-CDK4/CDK6 And Cyclin E-CDK2 Pathways: Implications For The Mechanism of Deficient Decidualization In An Immune-Based Mouse Model of Unexplained Recurrent Spontaneous Abortion

  2021cites this paper
• WEE1 kinase is a therapeutic vulnerability in CIC-DUX4 undifferentiated sarcoma

  2021cites this paper
• E2F1: Cause and Consequence of DNA Replication Stress

  2021cites this paper
• Effects of naringin on reversing cisplatin resistance and the Wnt/β-catenin pathway in human ovarian cancer SKOV3/CDDP cells

  2020cites this paper
• JAK/STAT pathway promotes Drosophila neuroblast proliferation via the direct CycE regulation

  2020cites this paper
• Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1

  2020cites this paper
• tRNA-Derived Small RNAs: Novel Epigenetic Regulators

  2020cites this paper
• Sofosbuvir Activates EGFR-Dependent Pathways in Hepatoma Cells with Implications for Liver-Related Pathological Processes

  2020cites this paper
• The diverse roles of SPOP in prostate cancer and kidney cancer

  2020cites this paper
• Restriction point regulation at the crossroads between quiescence and cell proliferation

  2020cites this paper
• Recent advances with cyclin-dependent kinase inhibitors: therapeutic agents for breast cancer and their role in immuno-oncology

  2019cites this paper
• Three-dimensional microenvironmental priming of human mesenchymal stem cells in hydrogels facilitates efficient and rapid retroviral gene transduction via accelerated cell cycle synchronization

  2019cites this paper
• Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice.

  2019cites this paper
• Molecular Pathway and Fluorescence In Situ Hybridization Testing of ERBB2 (HER2) Gene Amplification in Invasive Ductal Carcinoma of Breast

  2019cites this paper
• Replication Licensing Aberrations, Replication Stress, and Genomic Instability.

  2019cites this paper
• Determining the endocrine disruption potential of industrial chemicals using an integrative approach: Public databases, in vitro exposure, and modeling receptor interactions.

  2019cites this paper
• Reprogramming the genome: role of the cell cycle.

  2019cites this paper
• Mir-152 Regulates 3T3-L1 Preadipocyte Proliferation and Differentiation

  2019cites this paper
• Mechanistic Insights Into DREAM and RB Control of the Cell Cycle

  2019cites this paper
• Genome-Wide Analysis of Cell Cycle-Regulating Genes in the Symbiotic Dinoflagellate Breviolum minutum

  2019cites this paper
• DNA replication and mitotic entry: A brake model for cell cycle progression

  2019cites this paper
• Regulation of Cell Cycle Entry and Exit: A Single Cell Perspective.

  2019cites this paper
• tRNA-Derived Small Non-Coding RNAs as Novel Epigenetic Molecules Regulating Adipogenesis

  2019cites this paper
• Intrinsic checkpoint deficiency during cell cycle re-entry from quiescence

  2019cites this paper
• Replication stress: Driver and therapeutic target in genomically instable cancers.

  2019cites this paper
• The Apparent Requirement for Protein Synthesis during G2 Phase Is due to Checkpoint Activation

  2019cites this paper
• Physiologic levels of resistin induce a shift from proliferation to apoptosis in macrophage and VSMC co‐culture

  2018cites this paper
• Death of a Dogma: Cyclin D Activates Rb by Mono-phosphorylation

  2018cites this paper
• Curcumin analogue 1,5-bis(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl)phenyl)penta-1,4-dien-3-one mediates growth arrest and apoptosis by targeting the PI3K/AKT/mTOR and PKC-theta signaling pathways in human breast carcinoma cells.

  2018cites this paper
• Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress

  2018cites this paper
• Precise detection of S phase onset reveals decoupled G1/S transition events

  2018cites this paper
• miR-144-3p Promotes Adipogenesis Through Releasing C/EBPα From Klf3 and CtBP2

  2018cites this paper
• D-type Cyclins and Cancer

  2018influential citation
• D-Type Cyclins and Gene Transcription

  2018cites this paper
• Evaluation of Cyclin D1 Expression in Aggressive and Nonaggressive Central Giant Cell Granuloma of the Jaws

  2018cites this paper
• PIN1 in Cell Cycle Control and Cancer

  2018cites this paper
• Pathways for maintenance of telomeres and common fragile sites during DNA replication stress

  2018cites this paper
• MicroRNA-200b regulates preadipocyte proliferation and differentiation by targeting KLF4.

  2018cites this paper
• Cyclin E Overexpression Sensitizes Triple-Negative Breast Cancer to Wee1 Kinase Inhibition

  2018cites this paper
• Estrogen receptor beta signaling inhibits PDGF induced human airway smooth muscle proliferation.

  2018cites this paper
• Blocking of autocrine IGF-1 reduces viability of human umbilical cord mesenchymal stem cells via inhibition of the Akt/Gsk-3β signaling pathway.

  2018cites this paper
• Modeling the Influence of Seasonal Differences in the HPA Axis on Synchronization of the Circadian Clock and Cell Cycle

  2018cites this paper
• Aberrant miRNAs Regulate the Biological Hallmarks of Glioblastoma

  2018cites this paper
• Genome-wide analysis of cell cycle-regulating genes in the symbiotic dinoflagellate Symbiodinium minutum

  2018cites this paper
• LAST, a c-Myc-inducible long noncoding RNA, cooperates with CNBP to promote CCND1 mRNA stability in human cells

  2017cites this paper
• Effect of sinapic acid on hair growth promoting in human hair follicle dermal papilla cells via Akt activation

  2017cites this paper
• Rapid DNA replication origin licensing protects stem cell pluripotency

  2017cites this paper
• Cyclin E Deregulation and Genomic Instability.

  2017cites this paper
• High expression of nuclear CCNE 1 is associated with disease progression in nasopharyngeal carcinoma patients

  2017cites this paper
• Rapid Breast Cancer Disease Progression Following Cyclin Dependent Kinase 4 and 6 Inhibitor Discontinuation

  2017cites this paper
• TARGETING AUTOPHAGY TO IMPROVE EFFICACY OF CDK4/6 INHIBITION IN BREAST CANCER

  2017cites this paper
• Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons

  2017cites this paper
• Application of cell-based assays for toxicity characterization of complex wastewater matrices: Possible applications in wastewater recycle and reuse.

  2017cites this paper
• Role of MicroRNA-93 I in Pathogenesis of Left Ventricular Remodeling via Targeting Cyclin-D1

  2017cites this paper
• The Cul3 Ubiquitin Ligase: An Essential Regulator of Diverse Cellular Processes

  2017cites this paper
• The DNA replication stress checkpoint transcriptional response and its role in replication stress tolerance

  2017cites this paper
• The Role of the Transcriptional Response to DNA Replication Stress

  2017cites this paper
• SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function

  2017cites this paper
• Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification

  2017influential citation
• A United States Patent ( 19 ) 11 Patent Number : 6 , 045 , 999

  2017cites this paper
• Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription

  2016cites this paper
• Caracterización de las alteraciones estructurales y funcionales de la corteza cerebral de ratones mutantes de pérdida y ganancia de función de DYRK1A

  2016cites this paper
• Ligand activation of peroxisome proliferator-activated receptor-β/δ suppresses liver tumorigenesis in hepatitis B transgenic mice.

  2016cites this paper