Differential Induction of Inflammatory Cytokines and Reactive Oxygen Species in Murine Peritoneal Macrophages and Resident Fresh Bone Marrow Cells by Acute Staphylococcus aureus Infection: Contribution of Toll-Like Receptor 2 (TLR2)

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Inflammation

• Publication date

  2015-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s10753-014-0026-8PMID 25266881
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Possible Role of Toll‐like Receptor‐2 in the Intracellular Survival of Staphylococcus aureus in Murine Peritoneal Macrophages: Involvement of Cytokines and Anti‐Oxidant Enzymes

  2014influential reference
• Expression of CXCR1 (Interleukin-8 Receptor) in Murine Macrophages After Staphylococcus aureus Infection and its Possible Implication on Intracellular Survival Correlating with Cytokines and Bacterial Anti-Oxidant Enzymes

  2014cited by this paper
• Contribution of Toll-Like Receptor 2 to the Innate Response against Staphylococcus aureus Infection in Mice

  2013cited by this paper
• Intra-cellular Staphylococcus aureus alone causes infection in vivo.

  2013cited by this paper
• Inhibition of Toll-Like Receptor-Mediated Inflammation In Vitro and In Vivo by a Novel Benzoxaborole

  2013cited by this paper
• Dissecting negative regulation of Toll-like receptor signaling.

  2012cited by this paper
• Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

  2012cited by this paper
• Staphylococcal Superantigen-Like Protein 3 Binds to the Toll-Like Receptor 2 Extracellular Domain and Inhibits Cytokine Production Induced by Staphylococcus aureus, Cell Wall Component, or Lipopeptides in Murine Macrophages

  2012influential reference
• Lung microenvironment contributes to the resistance of alveolar macrophages to develop tolerance to endotoxin*

  2012cited by this paper
• Gentamicin in Combination with Ascorbic Acid Regulates the severity of Staphylococcus aureus Infection–Induced Septic Arthritis in Mice

  2012cited by this paper
• Ampicillin alone and in combination with riboflavin modulates Staphylococcus aureus infection induced septic arthritis in mice.

  2012cited by this paper
• Macrophage phagocytosis of neutrophils at inflammatory/infectious foci: a cooperative mechanism in the control of infection and infectious inflammation

  2011cited by this paper
• A modulatory interleukin-10 response to staphylococcal peptidoglycan prevents Th1/Th17 adaptive immunity to Staphylococcus aureus.

  2011cited by this paper
• Neutrophils in innate host defense against Staphylococcus aureus infections

  2011cited by this paper
• TLR2 enhances NADPH oxidase activity and killing of Staphylococcus aureus by PMN.

  2011cited by this paper
• Method of bacterial killing differentially affects the human innate immune response to Staphylococcus epidermidis

  2011cited by this paper
• TLR signaling augments macrophage bactericidal activity through mitochondrial ROS

  2011cited by this paper
• T and B Cells Are Not Required for Clearing Staphylococcus aureus in Systemic Infection Despite a Strong TLR2–MyD88-Dependent T Cell Activation

  2011cited by this paper
• Artesunate in combination with oxacillin protect sepsis model mice challenged with lethal live methicillin-resistant Staphylococcus aureus (MRSA) via its inhibition on proinflammatory cytokines release and enhancement on antibacterial activity of oxacillin.

  2011cited by this paper
• Oxidative Toxicity in Neurodegenerative Diseases: Role of Mitochondrial Dysfunction and Therapeutic Strategies

  2011cited by this paper
• Contribution of Catalase and Superoxide Dismutase to the Intracellular Survival of Clinical Isolates of Staphylococcus aureus in Murine Macrophages

  2010cited by this paper
• Divergent roles of Toll‐like receptor 2 in response to lipoteichoic acid and Staphylococcus aureus in vivo

  2010cited by this paper
• Mycobacterium tuberculosis Lipoproteins Directly Regulate Human Memory CD4+ T Cell Activation via Toll-Like Receptors 1 and 2

  2010cited by this paper
• Annexin A2 tetramer activates human and murine macrophages through TLR4.

  2010cited by this paper
• Pattern recognition receptors and inflammation.

  2010cited by this paper
• Protective effects of interleukin-6 in lipopolysaccharide (LPS)-induced experimental endotoxemia are linked to alteration in hepatic anti-oxidant enzymes and endogenous cytokines.

  2010cited by this paper
• A Method for Generation of Bone Marrow-Derived Macrophages from Cryopreserved Mouse Bone Marrow Cells

  2010cited by this paper
• Staphylococcal Peptidoglycan Co-Localizes with Nod2 and TLR2 and Activates Innate Immune Response via Both Receptors in Primary Murine Keratinocytes

  2010cited by this paper
• Interaction of staphylococci with bone

  2010cited by this paper
• Simultaneous lack of catalase and beta-toxin in Staphylococcus aureus leads to increased intracellular survival in macrophages and epithelial cells and to attenuated virulence in murine and ovine models.

  2009cited by this paper
• Staphylococcus aureus: new evidence for intracellular persistence.

  2009cited by this paper
• Staphylococcal catalase protects intracellularly survived bacteria by destroying H2O2 produced by the murine peritoneal macrophages.

  2009cited by this paper
• Critical Role of NOD2 in Regulating the Immune Response to Staphylococcus aureus

  2009cited by this paper
• Inflammation and oxidative stress in vertebrate host–parasite systems

  2009cited by this paper
• Macrophages Generate Reactive Oxygen Species in Response to Minimally Oxidized Low-Density Lipoprotein: Toll-Like Receptor 4– and Spleen Tyrosine Kinase–Dependent Activation of NADPH Oxidase 2

  2009cited by this paper
• Staphylococcal catalase regulates its virulence and induces arthritis in catalase deficient mice.

  2009cited by this paper
• Staphylococcus aureus infections.

  2009cited by this paper
• Treponema denticola Suppresses Expression of Human β-Defensin-3 in Gingival Epithelial Cells through Inhibition of the Toll-Like Receptor 2 Axis

  2009cited by this paper
• Modulation of adaptive immunity with Toll-like receptors.

  2009cited by this paper
• Toll-like receptor 2 is essential for the sensing of oxidants during inflammation.

  2009cited by this paper
• TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours

  2008cited by this paper
• A Potential New Pathway for Staphylococcus aureus Dissemination: The Silent Survival of S. aureus Phagocytosed by Human Monocyte-Derived Macrophages

  2008cited by this paper
• TLR4-induced IFN-γ production increases TLR2 sensitivity and drives Gram-negative sepsis in mice

  2008cited by this paper
• TLR2-Mediated Survival of Staphylococcus aureus in Macrophages: A Novel Bacterial Strategy against Host Innate Immunity

  2008cited by this paper
• Staphylococcal peptidoglycan initiates an inflammatory response and procoagulant activity in human vascular endothelial cells: a comparison with highly purified lipoteichoic acid and TSST-1.

  2008cited by this paper
• Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model.

  2008cited by this paper
• Invasion of bone cells by Staphylococcus epidermidis.

  2007cited by this paper
• TLR2-Mediated Survival of Staphylococcus aureus in Macrophages: A Novel Bacterial Strategy against Host Innate Immunity1

  2007cited by this paper
• TLR2 but not TLR4 Signalling is Critically Involved in the Inhibition of IFN‐γ‐induced Killing of Mycobacteria by Murine Macrophages

  2007cited by this paper
• The diacylated lipopeptide FSL-1 enhances phagocytosis of bacteria by macrophages through a Toll-like receptor 2-mediated signalling pathway.

  2007cited by this paper
• Pathogen recognition and innate immunity.

  2006cited by this paper
• Recognition of Staphylococcus aureus by the Innate Immune System

  2005cited by this paper
• Interleukin 12 and tumor necrosis factor a are costimulators of interferon y production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist

  2005cited by this paper
• Staphylococcus aureus Peptidoglycan Is a Toll-Like Receptor 2 Activator: a Reevaluation

  2005cited by this paper
• Internalization of bacteria by osteoblasts in a patient with recurrent, long-term osteomyelitis. A case report.

  2005cited by this paper
• Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain

  2005cited by this paper
• CD36 is a sensor of diacylglycerides

  2005cited by this paper
• Toll-Like Receptor 2 Is Required for Optimal Control of Listeria monocytogenes Infection

  2004cited by this paper
• Regulation of virulence determinants in Staphylococcus aureus: complexity and applications.

  2004cited by this paper
• Toll-like receptors as an escape mechanism from the host defense.

  2004cited by this paper
• IL-6, RANKL, TNF-alpha/IL-1: interrelations in bone resorption pathophysiology.

  2004cited by this paper
• Selective induction of matrix metalloproteinases by Borrelia burgdorferi via toll-like receptor 2 in monocytes.

  2004cited by this paper
• IL-6, RANKL, TNF-alpha/IL-1: interrelations in bone resorption pathophysiology.

  2004cited by this paper
• Hard labour: bacterial infection of the skeleton.

  2003cited by this paper
• The immunopathogenesis of sepsis

  2002cited by this paper
• Yersinia V–Antigen Exploits Toll-like Receptor 2 and CD14 for Interleukin 10–mediated Immunosuppression

  2002cited by this paper
• Interleukin-1beta stimulates transendothelial mobilization of human peripheral blood mononuclear cells with a potential to differentiate into osteoclasts in the presence of osteoblasts.

  2001cited by this paper
• The Production of IFN-γ by IL-12/IL-18-Activated Macrophages Requires STAT4 Signaling and Is Inhibited by IL-41

  2001cited by this paper
• The Role of Toll-like Receptors (TLRs) in Bacteria-induced Maturation of Murine Dendritic Cells (DCs)

  2001cited by this paper
• Human Alveolar Macrophages and Granulocyte-macrophage Colony-stimulating Factor-induced Monocyte-derived Macrophages Are Resistant to H2O2 via Their High Basal and Inducible Levels of Catalase Activity*

  2001cited by this paper
• Cutting Edge: TLR2-Deficient and MyD88-Deficient Mice Are Highly Susceptible to Staphylococcus aureus Infection1

  2000cited by this paper
• Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity.

  2000cited by this paper
• Peptidoglycan and Lipoteichoic Acid from Staphylococcus aureus Induce Tumor Necrosis Factor Alpha, Interleukin 6 (IL-6), and IL-10 Production in Both T Cells and Monocytes in a Human Whole Blood Model

  2000cited by this paper
• In vivo internalization of Staphylococcus aureus by embryonic chick osteoblasts.

  2000cited by this paper
• Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2*

  1999cited by this paper
• Mechanisms of Internalization ofStaphylococcus aureus by Cultured Human Osteoblasts

  1999cited by this paper
• Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.

  1999cited by this paper
• Mechanisms of Staphylococcus aureus invasion of cultured osteoblasts.

  1999cited by this paper
• Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing.

  1998cited by this paper
• Staphylococcus aureus infections.

  1998cited by this paper
• Surface-associated protein from Staphylococcus aureus stimulates osteoclastogenesis: possible role in S. aureus-induced bone pathology.

  1998cited by this paper
• Role of oxidants in microbial pathophysiology

  1997cited by this paper
• A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits.

  1996cited by this paper
• Interleukin‐6 and soluble interleukin‐6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast‐like cell formation

  1996cited by this paper
• Surface‐associated proteins from Staphylococcus aureus demonstrate potent bone resorbing activity

  1995cited by this paper
• Internalization of Staphylococcus aureus by cultured osteoblasts.

  1995cited by this paper
• Gram-positive cell walls stimulate synthesis of tumor necrosis factor alpha and interleukin-6 by human monocytes

  1994cited by this paper
• Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

  1993cited by this paper
• Induction of release of tumor necrosis factor from human monocytes by staphylococci and staphylococcal peptidoglycans

  1993cited by this paper
• Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli.

  1991cited by this paper
• Inflammatory mediators and the destruction of bone.

  1991cited by this paper
• Bacterial defenses against oxidative stress.

  1990cited by this paper
• IL-6 is produced by osteoblasts and induces bone resorption.

  1990cited by this paper
• Interleukin‐1 and tumor necrosis factor stimulate the formation of human osteoclastlike cells in vitro

  1989cited by this paper
• Basic methods for the study of phagocytosis.

  1986cited by this paper
• [3] Basic methods for the study of phagocytosis

  1986cited by this paper
• W. W. Pigman

  1978cited by this paper
• Handbook of experimental immunology

  1967cited by this paper

• Supramolecular discrimination and diagnosis-guided treatment of intracellular bacteria

  2025cites this paper
• Cellular and microenvironmental cues that promote macrophage fusion and foreign body response

  2024cites this paper
• Ubiquitin specific peptidase 8 is critical for the onset of infectious osteomyelitis by targeting RIPK2 ubiquitination.

  2023cites this paper
• Extracellular fibrinogen-binding protein released by intracellular Staphylococcus aureus suppresses host immunity by targeting TRAF3

  2022cites this paper
• The Influence of Antibiotic Resistance on Innate Immune Responses to Staphylococcus aureus Infection

  2022cites this paper
• Detection of Immune Checkpoint Receptors – A Current Challenge in Clinical Flow Cytometry

  2021cites this paper
• Immunoregulation by type I interferons in the peritoneal cavity

  2021cites this paper
• Coating of a Novel Antimicrobial Nanoparticle with a Macrophage Membrane for the Selective Entry into Infected Macrophages and Killing of Intracellular Staphylococci

  2020cites this paper
• Phage-mediated adaptation of Staphylococcus aureus to the avian innate immune response

  2020cites this paper
• Prevalence of methicillin-resistant Staphylococcus aureus colonization among healthcare workers at a tertiary care hospital in northeastern Brazil

  2020cites this paper
• Baicalin protects mice from infection with methicillin‐resistant Staphylococcus aureus via alleviating inflammatory response

  2020cites this paper
• Mechanisms of Blood Brain Barrier Disruption by Different Types of Bacteria, and Bacterial–Host Interactions Facilitate the Bacterial Pathogen Invading the Brain

  2018cites this paper
• The Peritoneal Macrophages in Inflammatory Diseases and Abdominal Cancers.

  2018cites this paper
• Killing of S. aureus in murine peritoneal macrophages by Ascorbic acid along with antibiotics Chloramphenicol or Ofloxacin: Correlation with inflammation.

  2018cites this paper
• Dried Plum Polyphenolic Extract Combined with Vitamin K and Potassium Restores Trabecular and Cortical Bone in Osteopenic Model of Postmenopausal Bone Loss.

  2018cites this paper
• Dietary Bovine Lactoferrin Reduces Staphylococcus aureus in the Tissues and Modulates the Immune Response in Piglets Systemically Infected with Staphylococcus aureus

  2017cites this paper
• Dietary Bovine Lactoferrin Reduces Staphylococcus aureus in the Tissues and Modulates the Immune Response in Piglets Systemically Infected with S. aureus

  2017cites this paper
• A novel CCR-2/TLR-2 triggered signaling in murine peritoneal macrophages intensifies bacterial (Staphylococcus aureus) killing by reactive oxygen species through TNF-R1.

  2017cites this paper
• Staphylococcus aureus‐mediated blood–brain barrier injury: an in vitro human brain microvascular endothelial cell model

  2017cites this paper
• Expression of CXCR1 (IL-8 receptor A) in splenic, peritoneal macrophages and resident bone marrow cells after acute live or heat killed Staphylococcus aureus stimulation in mice.

  2017cites this paper
• Control of Methicillin-Resistant Staphylococcus aureus Pneumonia Utilizing TLR2 Agonist Pam3CSK4

  2016cites this paper
• Intracellularly survived Staphylococcus aureus after phagocytosis are more virulent in inducing cytotoxicity in fresh murine peritoneal macrophages utilizing TLR-2 as a possible target.

  2016cites this paper
• Riboflavin along with antibiotics balances reactive oxygen species and inflammatory cytokines and controls Staphylococcus aureus infection by boosting murine macrophage function and regulates inflammation

  2016cites this paper
• Murine macrophage response from peritoneal cavity requires signals mediated by chemokine receptor CCR-2 during Staphylococcus aureus infection

  2015influential citation
• The Innate Immune Response Against Staphylococcus aureus.

  2015cites this paper
• Host antioxidant enzymes and TLR-2 neutralization modulate intracellular survival of Staphylococcus aureus: Evidence of the effect of redox balance on host pathogen relationship during acute staphylococcal infection.

  2015cites this paper
• Toll-like receptor 2 and 6 interdependency in the erosive stage of Staphylococcus aureus induced septic arthritis mediated by IFN-γ and IL-6--A possible involvement of IL-17 in the progression of the disease.

  2015cites this paper