Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial.

A. Sartore-Bianchi,L. Trusolino,C. Martino,K. Bencardino,S. Lonardi,F. Bergamo,V. Zagonel,F. Leone,Ilaria Depetris,E. Martinelli,T. Troiani,F. Ciardiello,P. Racca,A. Bertotti,G. Siravegna,V. Torri,A. Amatu,S. Ghezzi,G. Marrapese,L. Palmeri,E. Valtorta,A. Cassingena,C. Lauricella,A. Vanzulli,D. Regge,S. Veronese,P. Comoglio,A. Bardelli,S. Marsoni,S. Siena

Published 2016 in The Lancet Oncology

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