Evolution of canine parvovirus involved loss and gain of feline host range.

Canine parvovirus (CPV) type-2 emerged as a new virus infecting dogs in 1978, and it was probably derived as a variant of feline panleukopenia virus or of a closely related virus infecting another carnivore. CPV type-2 was subsequently replaced in nature by antigenically variant viruses (CPV type-2a and CPV type-2b) which now coexist in dog populations worldwide. We show that CPV type-2 isolates did not replicate in cats, but that both CPV type-2a and CPV type-2b isolates replicated efficiently. About 10% of the viruses isolated from cats with natural parvovirus disease were antigenically indistinguishable from CPV type-2a or type-2b. The capsid protein gene sequence of a 1990 feline parvovirus isolate ("FPV-24") was essentially identical to the sequence of CPV type-2b viruses from dogs. The loss and reacquisition of the feline host range in CPV was most likely due in each case to small numbers of changes in a region of the virus capsid where three protein monomers interact.

• Publication year

  1996

• Venue

  Virology

• Publication date

  1996-01-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1006/VIRO.1996.0021PMID 8560765
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Evolution of the feline-subgroup parvoviruses and the control of canine host range in vivo

  1995cited by this paper
• Two dominant neutralizing antigenic determinants of canine parvovirus are found on the threefold spike of the virus capsid.

  1994cited by this paper
• Hantaviruses and the Hantavirus Outbreak in the United States: A Case Study in Disease Emergence a

  1994cited by this paper
• Mapping of determinants of the host range for canine cells in the genome of canine parvovirus using canine parvovirus/mink enteritis virus chimeric viruses.

  1994cited by this paper
• Antigenic and genomic variabilities among recently prevalent parvoviruses of canine and feline origin in Japan.

  1993cited by this paper
• Structure determination of feline panleukopenia virus empty particles

  1993cited by this paper
• Dolphin and porpoise morbilliviruses are genetically distinct from phocine distemper virus.

  1993cited by this paper
• Multiple amino acids in the capsid structure of canine parvovirus coordinately determine the canine host range and specific antigenic and hemagglutination properties

  1992cited by this paper
• Mutations adjacent to the dimple of the canine parvovirus capsid structure affect sialic acid binding.

  1992cited by this paper
• The Emergence of Simian/Human Immunodeficiency Viruses

  1992cited by this paper
• Canine and feline host ranges of canine parvovirus and feline panleukopenia virus: distinct host cell tropisms of each virus in vitro and in vivo

  1992cited by this paper
• The three-dimensional structure of canine parvovirus and its functional implications.

  1991cited by this paper
• Rapid antigenic-type replacement and DNA sequence evolution of canine parvovirus

  1991cited by this paper
• Nucleotide sequence of feline panleukopenia virus: comparison with canine parvovirus identifies host-specific differences.

  1990cited by this paper
• The global spread and replacement of canine parvovirus strains.

  1988cited by this paper
• Canine host range and a specific epitope map along with variant sequences in the capsid protein gene of canine parvovirus and related feline, mink, and raccoon parvoviruses.

  1988cited by this paper
• Conservation of the putative receptor attachment site in picornaviruses.

  1988cited by this paper
• The autonomously replicating parvoviruses of vertebrates.

  1987cited by this paper
• Natural variation of canine parvovirus.

  1985cited by this paper

• Detection and Molecular Characterisation of Protoparvovirus carnivoran1 in Golden Jackals (Canis aureus) in Croatia

  2026cites this paper
• Feline panleukopenia virus and canine parvovirus: development of two qPCR assays with high-resolution melting analysis and molecular epidemiology in dogs and cats from Northen Italy in 2017–2023

  2026cites this paper
• Genetic variability and phylogenetic analysis of the VP2 gene of feline parvovirus in Harbin

  2026cites this paper
• Retrospective analysis of clustered neuroinflammatory and neurodegenerative diseases in captive lions in the early 1970s

  2025cites this paper
• Molecular survey of canine parvovirus type 2: the emergence of subtype 2c in New Zealand

  2025cites this paper
• The Evolution of Virulence: An Ecological Perspective.

  2025cites this paper
• Distinct evolutionary patterns of endemic and emerging parvoviruses, and the origin of a new pandemic virus

  2025cites this paper
• An engineered canine-mouse chimeric neutralizing antibody provides therapeutic effects against canine parvovirus infection.

  2025cites this paper
• Structural insights into mink enteritis virus host specificity: capsid architecture, receptor recognition, and evolutionary dynamics

  2025cites this paper
• Cross-species characterization of feline parvovirus and Feline-Origin canine parvovirus Southern China (2023–2024): insights into epidemiology, genetic evolution and recombination

  2025cites this paper
• Epidemiological status and genome characteristics of canine parvovirus in China from 2022 to 2024

  2025cites this paper
• First Isolation and Characterization of Feline Panleukopenia Virus From Wild Raccoon Dogs in the Residential Area of Shanghai, China

  2024cites this paper
• Prevalence and diagnosis of canine parvovirus

  2024cites this paper
• Comparative genomics of canine parvovirus in South America: Diversification patterns in local populations.

  2024cites this paper
• Molecular characterization of full-length VP2 gene of canine parvovirus type 2 strains circulating in Egypt 2019-2021.

  2024cites this paper
• Assessing Immune Evasion Potential and Vaccine Suitability of a Feline Panleukopenia Virus Strain

  2024cites this paper
• Investigation of canine parvovirus occurrence in cats with clinical signs of feline panleukopenia in Slovakia – pilot study

  2024cites this paper
• Epidemiology, molecular prevalence and prevention on canine parvovirus in India: A review

  2024cites this paper
• Parvovirus-Infektionen bei Katzen in Tierheimen

  2023cites this paper
• Genetic diversity and relatedness of feline parvovirus in Vietnam and its potential implications for canine-feline transmission

  2023cites this paper
• First isolation and molecular characterization of canine parvovirus-type 2b (CPV-2b) from red foxes (Vulpes vulpes) living in the wild habitat of Turkey

  2023cites this paper
• Prevalence of Canine Parvovirus Infection in Khartoum State, Sudan

  2023cites this paper
• Development of an accurate and rapid method for whole genome characterization of canine parvovirus.

  2023cites this paper
• Feline Parvovirus Lethal Outbreak in a Group of Adult Cohabiting Domestic Cats

  2023cites this paper
• Serum pentraxin 3 levels in cats with feline parvovirus infection

  2023cites this paper
• Tracing the Genetic Evolution of Canine Parvovirus Type 2 (CPV-2) in Thailand

  2022influential citation
• Real time PCR typing of canine parvovirus types in various regions of northern India

  2022cites this paper
• Molecular analysis of the full-length VP2 gene of Brazilian strains of canine parvovirus 2 shows genetic and structural variability between wild and vaccine strains.

  2022cites this paper
• Molecular Investigation of Recent Canine Parvovirus-2 (CPV-2) in Italy Revealed Distinct Clustering

  2022cites this paper
• Genetic characterization and evolutionary analysis of canine parvovirus in Tangshan, China

  2022cites this paper
• Characterization of the VP2 and NS1 genes from canine parvovirus type 2 (CPV-2) and feline panleukopenia virus (FPV) in Northern China

  2022cites this paper
• An overview of viral mutagenesis and the impact on pathogenesis of SARS-CoV-2 variants

  2022cites this paper
• Viren mit einzelsträngigem DNA-Genom

  2021cites this paper
• Novel detection of Canine Parvovirus 2c in domestic cats at Baghdad city, Iraq

  2021cites this paper
• Retrospective longitudinal study on Canine and Feline Parvovirus Infections in Al Ain, United Arab Emirates

  2021cites this paper
• Natural infection of parvovirus in wild fishing cats (Prionailurus viverrinus) reveals extant viral localization in kidneys

  2021cites this paper
• Predominance of canine parvovirus 2b in Japan: an epidemiological study during 2014-2019

  2021cites this paper
• Nucleotide sequences of the infectious DNA clones of two mink enteritis virus isolates exhibit the diversity of the terminal palindromic sequences and predicted secondary structures.

  2021cites this paper
• Genetic diversity of canine parvovirus variants, circulating in Nigeria.

  2021cites this paper
• Isolation and Identification of Three Parvovirus Strains in Rac- coon Dogs from Liaoning Province, China

  2021cites this paper
• Emerging Parvoviruses in Domestic Cats

  2021cites this paper
• Molecular Investigation of Canine Parvovirus-2 (CPV-2) Outbreak in Nevis Island: Analysis of the Nearly Complete Genomes of CPV-2 Strains from the Caribbean Region

  2021influential citation
• Canine parvovirus is shed infrequently by cats without diarrhoea in multi-cat environments.

  2021cites this paper
• Genomic Variability of Canine Parvoviruses from a Selected Population of Dogs and Cats in Sri Lanka

  2021cites this paper
• Host and parasite traits predict cross-species parasite acquisition by introduced mammals

  2021cites this paper
• The detection of canine parvovirus type 2c of Asian origin in dogs in Romania evidenced its progressive worldwide diffusion

  2021cites this paper
• PARVOVIRAL GENOMES IN HUMAN SOFT TISSUES AND BONES OVER DECADES

  2021cites this paper
• Integrated Use of Molecular Techniques to Detect and Genetically Characterise DNA Viruses in Italian Wolves (Canis lupus italicus)

  2021cites this paper
• Evaluation of an in-house indirect enzyme-linked immunosorbent assay of feline panleukopenia VP2 subunit antigen in comparison to hemagglutination inhibition assay to monitor tiger antibody levels by Bayesian approach

  2020cites this paper
• Domestic dog origin of Carnivore Protoparvovirus 1 infection in a rescued free-ranging guiña (Leopardus guigna) in Chile.

  2020cites this paper
• A history of canine parvovirus in Australia: what can we learn?

  2020cites this paper
• Epidemiology and molecular characterization of Carnivore protoparvovirus-1 infection in the wild felid Leopardus guigna in Chile.

  2020cites this paper
• Analysis of canine parvoviruses circulating in Australia reveals predominance of variant 2b and identifies feline parvovirus-like mutations in the capsid proteins.

  2020cites this paper
• Carnivore Protoparvovirus-1 Associated With an Outbreak of Hemorrhagic Gastroenteritis in Small Indian Civets

  2020cites this paper
• A Mini-Review on the Epidemiology of Canine Parvovirus in China

  2020cites this paper
• Phylogenetic, Evolutionary and Structural Analysis of Canine Parvovirus (CPV-2) Antigenic Variants Circulating in Colombia

  2020cites this paper
• Phylogenetic analysis of canine parvoviruses from Turkey

  2020cites this paper
• Phylogenetic and Geospatial Evidence of Canine Parvovirus Transmission between Wild Dogs and Domestic Dogs at the Urban Fringe in Australia

  2020cites this paper
• Diagnostic Challenges in Canine Parvovirus 2c in Vaccine Failure Cases

  2020cites this paper
• Epidemiology, molecular characterization and risk factors of Carnivore protoparvovirus-1 infection and disease in the wild felid Leopardus guigna in Chile

  2020influential citation
• Molecular characterisation of canine parvoviruses from clinical samples and vaccines in Nigeria.

  2020cites this paper
• Genetic characterization of Carnivore Parvoviruses in Spanish wildlife reveals domestic dog and cat-related sequences.

  2020cites this paper
• The increasing prevalence of CPV-2c in domestic dogs in China

  2020cites this paper
• First characterization of a canine parvovirus causing fatal disease in coatis (Nasua nasua)

  2019cites this paper
• Feline Virome—A Review of Novel Enteric Viruses Detected in Cats

  2019cites this paper
• Food web structure selects for parasite host range

  2019cites this paper
• Distribution of Carnivore protoparvovirus 1 in free-living leopard cats (Prionailurus bengalensis chinensis) and its association with domestic carnivores in Taiwan

  2019cites this paper
• Canine parvovirus detected from a serval (Leptailurus serval) in South Africa

  2019cites this paper
• Carnivore Parvovirus Ecology in the Serengeti Ecosystem: Vaccine Strains Circulating and New Host Species Identified

  2019cites this paper
• Transmission ecology of canine parvovirus in a multi-host, multi-pathogen system

  2019cites this paper
• Identification of a novel parvovirus in domestic cats.

  2019cites this paper
• Limited Intrahost Diversity and Background Evolution Accompany 40 Years of Canine Parvovirus Host Adaptation and Spread

  2019cites this paper
• Onward transmission of viruses: how do viruses emerge to cause epidemics after spillover?

  2019cites this paper
• Emergence of canine parvovirus type 2c in domestic dogs and cats from Thailand

  2019cites this paper
• Molecular epidemiology of canine parvovirus type 2 in Italy from 1994 to 2017: recurrence of the CPV-2b variant

  2019cites this paper
• Molecular Characterization and Evolutionary Analyses of Carnivore Protoparvovirus 1 NS1 Gene

  2019cites this paper
• Molecular detection of canine bufaviruses in wild canids

  2019cites this paper
• Development of a reverse genetics system for a feline panleukopenia virus

  2018cites this paper
• The phylogenomics of evolving virus virulence

  2018cites this paper
• Molecular characterization of canine parvovirus variants (CPV-2a, CPV-2b, and CPV-2c) based on the VP2 gene in affected domestic dogs in Ecuador

  2018cites this paper
• First genetic detection and characterization of canine parvovirus from diarrheic dogs in Zambia

  2018cites this paper
• Genetic characterization of parvoviruses in domestic cats in Henan province, China

  2018cites this paper
• Inter- and intracontinental migrations and local differentiation have shaped the contemporary epidemiological landscape of canine parvovirus in South America

  2018cites this paper
• Molecular methods for identification of antigenic types of canine parvovirus

  2018cites this paper
• Bioclimatic and altitudinal variables influence the potential distribution of canine parvovirus type 2 worldwide

  2018cites this paper
• Investigation on Canine parvovirus circulation in dogs from Sicily (Italy) by biomolecular assay

  2018cites this paper
• Emergence of novel canine parvovirus type 2 and its pathogenesis in raccoon dogs.

  2018cites this paper
• MicroRNA expression analysis of feline and canine parvovirus infection in vivo (felis)

  2017cites this paper
• FELINE PANLEUKOPENIA VIRUS INFECTION IN A CAPTIVE-BRED BENGAL TIGER ( AND A LEOPARD ( )

  2017cites this paper
• Canine parvovirus type 2 (CPV-2) and Feline panleukopenia virus (FPV) codon bias analysis reveals a progressive adaptation to the new niche after the host jump.

  2017cites this paper
• The genetic evolution of canine parvovirus – A new perspective

  2017cites this paper
• Genetic Analysis of Feline Panleukopenia Virus Full‐length VP2 Gene in Domestic Cats Between 2006–2008 and 2012–2014, Portugal

  2017cites this paper
• Substitutions at residues 300 and 389 of the VP2 capsid protein serve as the minimal determinant of attenuation for canine parvovirus vaccine strain 9985-46.

  2017cites this paper
• Filogenetska analiza VP2 gena parvovirusa pasa u Republici Hrvatskoj

  2017cites this paper
• Host shifts result in parallel genetic changes when viruses evolve in closely related species

  2017cites this paper
• Genetic characterization of canine parvovirus from dogs in Pakistan.

  2017cites this paper
• Evolutionary and genetic analysis of the VP2 gene of canine parvovirus

  2017cites this paper
• Molecular characterization of feline panleukopenia virus isolated from mink and its pathogenesis in mink.

  2017cites this paper
• GENETIC CHARACTERIZATION OF CANINE PARVOVIRUS IN SYMPATRIC FREE-RANGING WILD CARNIVORES IN PORTUGAL

  2017cites this paper
• Canine parvovirus: the worldwide occurrence of antigenic variants.

  2016cites this paper