Adjuvant radiotherapy for early head and neck squamous cell carcinoma with perineural invasion: A systematic review

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Head and Neck

• Publication date

  2016-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/hed.24295PMID 26613965
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2014cited by this paper
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  2014influential reference
• Predictors of prognosis for squamous cell carcinoma of oral tongue

  2014cited by this paper
• Perineural invasion and expression of nerve growth factor can predict the progression and prognosis of oral tongue squamous cell carcinoma.

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  2012cited by this paper
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  2011cited by this paper
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  2006influential reference
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• Prognostic significance of perineural invasion in oral and oropharyngeal carcinoma.

  2004cited by this paper
• Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer.

  2004cited by this paper
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  2004cited by this paper
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  2003cited by this paper
• Influence of condition of surgical margins on local recurrence and disease-specific survival in oral and oropharyngeal cancer.

  2003cited by this paper
• Perineural invasion in squamous cell carcinoma of the head and neck.

  1998influential reference
• Prognostic significance of vascular and perineural invasion in cancer of the larynx.

  1998cited by this paper
• Prognostic factors in the recurrence of stage I and II squamous cell cancer of the oral cavity.

  1992cited by this paper

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  2024cites this paper
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