Perineural invasion in squamous cell carcinoma of the head and neck.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Archives of Otolaryngology - Head and Neck Surgery

• Publication date

  1998-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1001/ARCHOTOL.124.6.637PMID 9639472
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Management of the Neck in Cancer of the Larynx

  1999cited by this paper
• Perineural invasion in skin cancer of the head and neck: a review of nine cases.

  1995cited by this paper
• Treatment of stage I and II oral tongue cancer

  1993cited by this paper
• Prognostic factors in mobile tongue and floor of mouth carcinoma

  1989cited by this paper
• Clinical and pathologic prognostic variables in oropharyngeal squamous cell carcinoma.

  1989cited by this paper
• Microvascular invasion in cancer of the oral cavity and oropharynx.

  1987influential reference
• Prognostic implications of perineural spread in squamous carcinomas of the head and neck

  1986cited by this paper
• Surgical treatment of early-stage carcinoma of the oral tongue--wound adjuvant treatment be beneficial?

  1986influential reference
• Cervical lymph node metastases. Incidence and implications of extracapsular carcinoma.

  1985cited by this paper
• Vicissitudes of head and neck cancer

  1984cited by this paper
• Hayes Martin lecture. Vicissitudes of head and neck cancer.

  1984cited by this paper
• Perineural invasion in squamous cell skin carcinoma of the head and neck.

  1984cited by this paper
• Perineural spread by squamous carcinomas of the head and neck: a morphological study using antiaxonal and antimyelin monoclonal antibodies.

  1983cited by this paper
• Pain and Dysphagia in Patients with Squamous Carcinomas of the Head and Neck: The Role of Perineural Spread

  1982cited by this paper
• Perineural spread in squamous cell carcinomas of the head and neck: a clinicopathological study.

  1979cited by this paper
• Longitudinal Spread of Intraneurally Injected Local Anesthetics: An Experimental Study of the Initial Neural Distribution Following Intraneural Injections

  1978cited by this paper
• The therapeutic and prognostic implications of nerve invasion in cancer of the lower lip.

  1977cited by this paper
• Nature of the perineural space invaded by prostatic carcinoma

  1967cited by this paper
• Perineural lymphatics: myth or fact.

  1966cited by this paper
• The extension of cancer of the head and neck through peripheral nerves

  1963cited by this paper

• Metastatic neck involvement in oral squamous cell carcinoma: A retrospective clinicopathological study

  2026cites this paper
• Perineural Invasion and Survival in Pembrolizumab-Treated Head and Neck Squamous Cell Carcinoma.

  2026cites this paper
• Functional Improvement in Cranial Neuropathies From Perineural Cutaneous Squamous Cell Carcinoma After Immunotherapy: A Multicenter Case Series and Review.

  2026cites this paper
• Perineural and Intraneural Invasion as Prognostic Indicators in Salivary Gland Malignancies - An 18-year Institutional Retrospective Analysis.

  2026cites this paper
• Identification of clinical and pathologic features associated with extranodal extension in patients with HPV-mediated oropharyngeal squamous cell carcinoma.

  2025cites this paper
• Preoperative Systemic Inflammation Response Index Predicts Survival Outcome for Previously Irradiated Metachronous Secondary Head and Neck Cancer Patients

  2025cites this paper
• The impact of histopathology on prognosis of squamous cell carcinoma of the larynx: can we do better?

  2025cites this paper
• Significance of location and extent of perineural invasion in early‐stage oral cavity squamous cell carcinoma

  2025cites this paper
• Assessment of peri-neural invasion in oral cancer patients using MRI: A clinical and radiologic correlation study

  2025cites this paper
• Semiquantitative immunohistochemical (IHC) pixelwise H-score of mitochondrial transcription factor A (TFAM) in gastric adenocarcinoma (GAC): clinicopathological significance and association with p53 and HER2

  2025cites this paper
• Perineural Invasion Unveiled: Deciphering the Prognostic Impact of Diameter and Quantity Subcategories in Oral Cancer

  2025influential citation
• Grading systems and perineural invasion in oral squamous cell carcinoma - a disease-specific survival analysis

  2025cites this paper
• High level of KMT5C is associated to better prognosis and its knockdown increases proliferation in head and neck cancer.

  2025cites this paper
• A review of histopathologic assessment for head and neck oncologists.

  2025cites this paper
• Periostin-positive stellate cells associated with perineural invasion in pancreatic adenocarcinoma.

  2025cites this paper
• Neuregulin-induced HER3 activation drives migration in head and neck squamous cell carcinoma via HER2 and FAK signaling pathways

  2025cites this paper
• Perineural Invasion in Breast Cancer: A Comprehensive Review

  2025cites this paper
• The Relationships Among Perineural Invasion, Tumor–Nerve Interaction and Immunosuppression in Cancer

  2025cites this paper
• Prognostic Factors in Oral Squamous Cell Carcinoma: Systematic Review and Meta‐Analysis

  2025cites this paper
• Radiomics-Based Preoperative Contrast Enhanced CT Histogram Analysis and Shape Feature Extraction in Laryngeal Squamous Cell Carcinoma: Correlation with Histopathological Parameters.

  2025cites this paper
• Perineural Invasion Is Not an Independent Risk Factor for Recurrence and Lateral Neck Metastasis in Thyroid Cancer: A Propensity Score Matching Analysis.

  2025cites this paper
• Defining the cellular and molecular features of nerve-invaded cancer cells using a newly characterized experimental model

  2025cites this paper
• Understanding the role of nerves in head and neck cancers - a review

  2025cites this paper
• Survival After Orbital Exenteration for Primary Cutaneous Squamous Cell Carcinoma: A Retrospective Cohort Study

  2025cites this paper
• PLAU serves as a prognostic biomarker correlated with perineural invasion in HNSCC.

  2025cites this paper
• Role of FDG-PET/CT in Determining DOI and PNI in OSCC—A Retrospective Study from Eastern India

  2025cites this paper
• The Role of Blood Inflammatory Biomarkers and Perineural and Lympho-Vascular Invasion to Detect Occult Neck Lymph Node Metastases in Early-Stage (T1-T2/N0) Oral Cavity Carcinomas

  2025cites this paper
• Adjuvant Radiotherapy in pT1‐2N0M0 Head and Neck Adenoid Cystic Carcinoma

  2025cites this paper
• Computed tomography-based absolute delta radiomics nomogram for predicting perineural invasion in hypopharyngeal squamous cell carcinoma.

  2025cites this paper
• Survival outcome of patient with pT1N0 biliary tract cancer treated with surgery alone.

  2024cites this paper
• Contrasting clinical outcomes and socio‐economic impact of young versus elderly‐onset oral squamous cell carcinoma, a novel health economic analysis

  2024cites this paper
• Operative Techniques in Otolaryngology: Head and Neck Surgery. Geisinger Medical Center Experience for Whole Mount Laryngectomy Specimen.

  2024cites this paper
• Is Perineural Invasion an Independent Prognostic Factor for Local Recurrence in Oral Squamous Cell Carcinoma?

  2024cites this paper
• Decoding lymphangiogenesis in oral squamous cell carcinoma: Emphasis on clinical and histopathological determinants of regional metastasis

  2024cites this paper
• Pattern of Recurrence in Carcinoma Oral Cavity: Prospective Longitudinal Study

  2024cites this paper
• Association of Patient and Tumor Characteristics With Outcomes in Young Head and Neck Squamous Cell Carcinoma Patients

  2024cites this paper
• Factors predicting peri-neural invasion in hypopharyngeal squamous cell carcinoma

  2024cites this paper
• Expression of p16INK4a, FLOT2, and EGFR in oropharyngeal carcinoma, prognostic significance and correlation with clinicopathological characteristics

  2024cites this paper
• Histopathological predictors of lymph node metastasis in oral cavity squamous cell carcinoma: a systematic review and meta-analysis

  2024influential citation
• Adjuvant therapy for intermediate risk factors in oral cancer: Can we reach a consensus?

  2024cites this paper
• Perineural invasion is a poor prognostic factor for sinonasal squamous cell carcinoma.

  2024cites this paper
• Perineural invasion and laryngeal squamous cell carcinoma: a systematic review

  2024cites this paper
• Comprehensive survival analysis of oral squamous cell carcinoma patients undergoing initial radical surgery

  2024cites this paper
• Diagnostic Accuracy of Contrast-Enhanced MRI for Detection of Perineural Spread in Head and Neck Cancer: A Systematic Review and Meta-Analysis

  2023cites this paper
• Perineural Invasion of Superior and Inferior Laryngeal Nerves in Advanced Stage Squamous Cell Carcinoma of the Larynx: A Case Series and Review

  2023influential citation
• Perineural Invasion Is a Significant Prognostic Factor in Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis

  2023cites this paper
• Prognostic Value of Hematological Parameters in Oral Squamous Cell Carcinoma

  2023cites this paper
• Paranasal sinus angiosarcoma with facial paralysis as a novel manifestation: a case report and literature review

  2023cites this paper
• Signi�cance of Worst Pattern of Invasion 5 in Early-Stage Oral Cavity Squamous Cell Carcinoma

  2023cites this paper
• Perineural invasion in nearby tissue adjacent to colorectal carcinoma with CD166 stem cell marker expression

  2023cites this paper
• Perineural Invasion (PNI) Definition, Histopathological Parameters of PNI in Oral Squamous Cell Carcinoma With Molecular Insight and Prognostic Significance

  2023cites this paper
• Significance of Worst Pattern of Invasion-5 in Early-Stage Oral Cavity Squamous Cell Carcinoma

  2023cites this paper
• Subcategorization of Perineural Invasion Stratifies Oral Cavity Squamous Cell Carcinoma Prognosis

  2023cites this paper
• Primary Tumor Staging for Oral Cancer and a Proposed Modification Incorporating Perineural Invasion: An International Multicenter Study

  2023cites this paper
• Perineural invasion predicts poor survival and cervical lymph node metastasis in oral squamous cell carcinoma

  2023cites this paper
• Prognostic Value of Lymphovascular Invasion in Patients With Pyriform Sinus Carcinoma Treated With Surgery Plus Adjuvant Chemo-/Radiotherapy

  2023cites this paper
• Rapid cancer cell perineural invasion utilizes amoeboid migration

  2023cites this paper
• Challenges seen with peri-neural invasion in head and neck cancer – A review article

  2023cites this paper
• Correlation between the perineural invasion and neck metastasis in patients with laryngeal carcinoma: a cross sectional study

  2023cites this paper
• Prediction of Lymphovascular and Perineural Invasion of Oral Squamous Cell Carcinoma by Combined Expression of p63 and Cyclin D1

  2023cites this paper
• Adjuvant radiotherapy mitigates impact of perineural invasion on oncologic outcomes in early-stage oral cavity squamous cell carcinoma. A multi-institutional analysis of 557 patients.

  2023cites this paper
• Perineural Invasion Predicts Local Recurrence and Poor Survival in Laryngeal Cancer

  2023cites this paper
• Pattern of failure after adjuvant radiation therapy in oral cavity cancer patients: Data from tertiary care institute in North India

  2023cites this paper
• Clinicopathological Characteristics, Treatment Patterns, and Outcomes in Patients with Laryngeal Cancer

  2023cites this paper
• Lymph node ratio as a survival predictor for head and neck squamous cell carcinoma with multiple adverse pathological features

  2023cites this paper
• Tumor volume as a predictor of survival in advanced laryngeal cancer treated with total laryngectomy

  2023influential citation
• Treatment outcomes and prognostic factors in oral tongue cancer: a 20-year retrospective study at the National Cancer Center, South Korea

  2022cites this paper
• Nerves in gastrointestinal cancer: from mechanism to modulations

  2022cites this paper
• Prognostic Implications of Skin Invasion in Locally Advanced Oral Cavity Squamous Cell Carcinoma.

  2022cites this paper
• Adding Concomitant Chemotherapy to Postoperative Radiotherapy in Oral Cavity Carcinoma with Minor Risk Factors: Systematic Review of the Literature and Meta-Analysis

  2022cites this paper
• Patterns and predictors of site‐specific recurrence in cervical cancer after radical hysterectomy

  2022cites this paper
• Label-free, real-time detection of perineural invasion and cancer margins in a murine model of head and neck cancer surgery

  2022cites this paper
• Epigenetic Regulations of Perineural Invasion in Head and Neck Squamous Cell Carcinoma

  2022cites this paper
• 18F-FDG PET, contrast CT and MRI to comprehensively diagnose and assess rare perineural spread of squamous cell carcinoma to the greater auricular nerve

  2022cites this paper
• Efficient Perineural Invasion Detection of Histopathological Images Using U-Net

  2022cites this paper
• Lumbosacral plexopathy caused by the perineural spread of pelvic malignancies: clinical aspects and imaging patterns

  2022cites this paper
• The road less travelled

  2022cites this paper
• Prognostic impact of perineural invasion in oral cancer: a systematic review

  2022cites this paper
• Neural Component of the Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma

  2022cites this paper
• Incorporation of adverse features in advanced oral cancer improves precision in staging and patient prognostication

  2022cites this paper
• Identification and validation of neurotrophic factor-related genes signature in HNSCC to predict survival and immune landscapes

  2022cites this paper
• Perineural invasion is a better prognostic factor than extranodal extension in head and neck cancer

  2022cites this paper
• Tumor Deposits and Perineural Invasion had Comparable Impacts on the Survival of Patients With Non-metastatic Colorectal Adenocarcinoma: A Population-Based Propensity Score Matching and Competing Risk Analysis

  2022influential citation
• Subcategorization of Perineural Invasion and Its Impact on Survival in Patients with Oral Squamous Cell Carcinoma

  2022cites this paper
• Long-Term Feasibility of 13.56 MHz Modulated Electro-Hyperthermia-Based Preoperative Thermoradiochemotherapy in Locally Advanced Rectal Cancer

  2022cites this paper
• The role of adjuvant therapy in pT4N0 laryngectomized patients: Multicentric observational study

  2022cites this paper
• Expectation-maximization algorithm leads to domain adaptation for a perineural invasion and nerve extraction task in whole slide digital pathology images

  2022cites this paper
• The complementary role of lymphovascular invasion and perineural invasion in the TNM staging process of rectal cancer

  2022cites this paper
• Lymph node ratio predicts recurrence-free survival and disease-specific survival of patients with pyriform sinus squamous cell carcinoma.

  2022cites this paper
• Elective Neck Dissection during Salvage Total Laryngectomy: Personal Experience

  2022cites this paper
• Are mechanical thrombectomy or thrombolysis universally cost-effective? A systematic review of the literature.

  2022cites this paper
• Spatial and Transcriptomic Analysis of Perineural Invasion in Oral Cancer

  2022cites this paper
• Delineation of Radiation Therapy Target Volumes for Lingual Nerve Involvement

  2022cites this paper
• Overexpression of UTX promotes tumor progression in Oral tongue squamous cell carcinoma patients receiving surgical resection: a case control study

  2021cites this paper
• Peri-neural Invasion in Oral Squamous Cell Carcinoma (OSCC): A Clinico-pathological Marker of OSCC Prognosis and Risk Assessment

  2021cites this paper
• Squamous and basal cell carcinoma with perineural invasion: pathophysiology and presentations

  2021cites this paper
• The impact of lymph node density as a predictive factor for survival and recurrence of tongue squamous cell carcinoma.

  2021cites this paper
• Outcomes of Post-Operative Treatment with Concurrent Chemoradiotherapy (CRT) in High-Risk Resected Oral Cavity Squamous Cell Carcinoma (OCSCC): A Multi-Institutional Collaboration

  2021cites this paper
• Perineural invasion/lymphovascular invasion double positive predicts distant metastasis and poor survival in T3–4 oral squamous cell carcinoma

  2021cites this paper
• Perineural Invasion as a Prognostic Factor in Laryngeal Squamous Cell Cancer: A Matched-Pair Survival Analysis

  2021influential citation