Molecular allergen profiling in horses by microarray reveals Fag e 2 from buckwheat as a frequent sensitizer

Companion animals are also affected by IgE‐mediated allergies, but the eliciting molecules are largely unknown. We aimed at refining an allergen microarray to explore sensitization in horses and compare it to the human IgE reactivity profiles.

• Publication year

  2018

• Venue

  Allergy. European Journal of Allergy and Clinical Immunology

• Publication date

  2018-02-27

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/all.13417PMID 29350763PMCID 6032949
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Buckwheat Grains and Buckwheat Products - Nutritional and Prophylactic Value of their Components - a Review

  2018cited by this paper
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  2018cited by this paper
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  2018cited by this paper
• The atopic march: current insights into skin barrier dysfunction and epithelial cell‐derived cytokines

  2017cited by this paper
• Allergies, with Focus on Food Allergies, in Humans and Their Animals

  2017cited by this paper
• Intelectin contributes to allergen-induced IL-25, IL-33 and TSLP expression and type 2 response in asthma and atopic dermatitis

  2017cited by this paper
• Debates in allergy medicine: Molecular allergy diagnosis with ISAC will replace screenings by skin prick test in the future

  2017cited by this paper
• Plant Pathogenesis-Related Proteins PR-10 and PR-14 as Components of Innate Immunity System and Ubiquitous Allergens.

  2017cited by this paper
• Comparing immediate‐type food allergy in humans and companion animals—revealing unmet needs

  2017cited by this paper
• Debates in Allergy Medicine: Allergy skin testing cannot be replaced by molecular diagnosis in the near future

  2017cited by this paper
• Allergic and Atopic Eczema in Humans and Their Animals

  2017cited by this paper
• Insect Bite Hypersensitivity in Horses is Associated with Airway Hyperreactivity

  2017cited by this paper
• Glycans and glycan-specific IgE in clinical and molecular allergology: Sensitization, diagnostics, and clinical symptoms.

  2017cited by this paper
• Molecular Recognition Profiles and Clinical Patterns of PR-10 Sensitization in a Birch-Free Mediterranean Area

  2017cited by this paper
• Checklist for One Health Epidemiological Reporting of Evidence (COHERE)

  2017cited by this paper
• Out of Breath: Asthma in Humans and Their Animals

  2017cited by this paper
• Occurrence and distribution of Malassezia species on skin and external ear canal of horses

  2016cited by this paper
• EAACI Molecular Allergology User's Guide

  2016cited by this paper
• Molecular, Structural and Immunological Characterization of Der p 18, a Chitinase-Like House Dust Mite Allergen

  2016cited by this paper
• Inflammatory Airway Disease of Horses—Revised Consensus Statement

  2016cited by this paper
• The Contribution of Buckwheat Genetic Resources to Health and Dietary Diversity

  2016cited by this paper
• Big data & analytics in health-care industry

  2015cited by this paper
• Comparative immunology of allergic responses.

  2015cited by this paper
• Pollen Allergies in Humans and their Dogs, Cats and Horses: Differences and Similarities

  2015cited by this paper
• Papain Degrades Tight Junction Proteins of Human Keratinocytes In Vitro and Sensitizes C57BL/6 Mice via the Skin Independent of its Enzymatic Activity or TLR4 Activation.

  2015cited by this paper
• Allergens in veterinary medicine

  2015cited by this paper
• Mimotopes for Api g 5, a Relevant Cross-reactive Allergen, in the Celery-Mugwort-Birch-Spice Syndrome

  2015cited by this paper
• Fagopyrins and Protofagopyrins: Detection, Analysis, and Potential Phototoxicity in Buckwheat.

  2015cited by this paper
• Evaluation of a diagnostic ELISA for insect bite hypersensitivity in horses using recombinant Obsoletus complex allergens.

  2014cited by this paper
• Bet v 1 from Birch Pollen Is a Lipocalin-like Protein Acting as Allergen Only When Devoid of Iron by Promoting Th2 Lymphocytes*

  2014cited by this paper
• Advances in allergen-microarray technology for diagnosis and monitoring of allergy: the MeDALL allergen-chip.

  2014cited by this paper
• Shrimp allergy beyond Tropomyosin in Italy: clinical relevance of Arginine Kinase, Sarcoplasmic calcium binding protein and Hemocyanin.

  2014cited by this paper
• New shrimp IgE-binding proteins involved in mite-seafood cross-reactivity.

  2014cited by this paper
• Genomic Insights into the Atopic Eczema-Associated Skin Commensal Yeast Malassezia sympodialis

  2013cited by this paper
• Sensitization to Malassezia in children with atopic dermatitis combined with food allergy

  2013cited by this paper
• Equine allergy therapy: update on the treatment of environmental, insect bite hypersensitivity, and food allergies.

  2013cited by this paper
• A WAO - ARIA - GA²LEN consensus document on molecular-based allergy diagnostics

  2013cited by this paper
• Italian Study on Buckwheat Allergy: Prevalence and Clinical Features of Buckwheat-Sensitized Patients in Italy

  2013cited by this paper
• Update on equine allergies.

  2013cited by this paper
• Malassezia Fungi Are Specialized to Live on Skin and Associated with Dandruff, Eczema, and Other Skin Diseases

  2012cited by this paper
• Equine insect bite hypersensitivity: what do we know?

  2012cited by this paper
• Equine atopic skin disease and response to allergen-specific immunotherapy: a retrospective study at the University of California-Davis (1991-2008).

  2012cited by this paper
• Buckwheat allergy: a potential problem in 21st century Britain

  2011cited by this paper
• Clinical manifestations, co‐sensitizations, and immunoblotting profiles of buckwheat‐allergic patients

  2011cited by this paper
• Bet v 1‐like pollen allergens of multiple Fagales species can sensitize atopic individuals

  2011cited by this paper
• Selective cloning, characterization, and production of the Culicoides nubeculosus salivary gland allergen repertoire associated with equine insect bite hypersensitivity.

  2011cited by this paper
• A new tool in the field of in-vitro diagnosis of allergy: preliminary results in the comparison of ImmunoCAP© 250 with the ImmunoCAP© ISAC

  2011cited by this paper
• Evaluation of the presence of house dust mites in horse rugs.

  2010cited by this paper
• Cloning, production and characterization of antigen 5 like proteins from Simulium vittatum and Culicoides nubeculosus, the first cross-reactive allergen associated with equine insect bite hypersensitivity.

  2010cited by this paper
• Intradermal skin tests in equine dermatology: a study of 83 horses.

  2010cited by this paper
• EpidemAAITO: Features of food allergy in Italian adults attending allergy clinics: a multi‐centre study

  2009influential reference
• Sensitization of skin mast cells with IgE antibodies to Culicoides allergens occurs frequently in clinically healthy horses.

  2009cited by this paper
• Maternal transfer of IgE and subsequent development of IgE responses in the horse (Equus callabus).

  2009cited by this paper
• Prostatic kallikrein: a new major dog allergen.

  2009cited by this paper
• In vitro allergy tests compared to intradermal testing in horses with recurrent airway obstruction.

  2009cited by this paper
• A survey of patients with self‐reported severe food allergies in Japan

  2008cited by this paper
• The IgE-reactive autoantigen Hom s 2 induces damage of respiratory epithelial cells and keratinocytes via induction of IFN-gamma.

  2008cited by this paper
• Epidemiologic and clinical features of anaphylaxis in Korea.

  2008cited by this paper
• Allergen-specific IgE in Icelandic horses with insect bite hypersensitivity and healthy controls, assessed by FcepsilonR1alpha-based serology.

  2008cited by this paper
• A comparison of intradermal testing and detection of allergen-specific immunoglobulin E in serum by enzyme-linked immunosorbent assay in horses affected with skin hypersensitivity.

  2007cited by this paper
• Application of the 16-kDa buckwheat 2 S storage albumin protein for diagnosis of clinical reactivity.

  2007cited by this paper
• Anaphylaxis after eating Italian pizza containing buckwheat as the hidden food allergen.

  2007cited by this paper
• The chitinase allergens Der p 15 and Der p 18 from Dermatophagoides pteronyssinus

  2006cited by this paper
• IgE and IgG antibodies in skin allergy of the horse.

  2006cited by this paper
• The role of sensitization to Malassezia sympodialis in atopic eczema.

  2006cited by this paper
• Purification and identification of angiotensin I-converting enzyme inhibitory peptide from buckwheat (Fagopyrum esculentum Moench)

  2006cited by this paper
• [Recurrent or chronic urticaria in thoroughbred race-horses: clinical observations].

  2004cited by this paper
• Monoclonal anti-equine IgE antibodies with specificity for different epitopes on the immunoglobulin heavy chain of native IgE.

  2003cited by this paper
• Inhibition of tumor growth in vitro by the extract of fagopyrum cymosum (fago-c).

  2003cited by this paper
• Microarrayed recombinant allergens for diagnosis of allergy

  2003cited by this paper
• Identification, characterization, and cloning of a complementary DNA encoding a 60-kd house dust mite allergen (Der f 18) for human beings and dogs.

  2003cited by this paper
• Composition and technological properties of the flour and bran from common and tartary buckwheat

  2003cited by this paper
• Buckwheat concentrate reduces serum glucose in streptozotocin-diabetic rats.

  2003cited by this paper
• Pepsin-Resistant 16-kD Buckwheat Protein Is Associated with Immediate Hypersensitivity Reaction in Patients with Buckwheat Allergy

  2002cited by this paper
• Microarrayed allergen molecules: diagnostic gatekeepers for allergy treatment

  2002cited by this paper
• Characterization and cloning of a major high molecular weight house dust mite allergen (Der f 15) for dogs.

  2001cited by this paper
• Buckwheat allergy

  2001cited by this paper
• Editorial. Buckwheat allergy. 2001;56:703-704.

  2001cited by this paper
• Molecular and Immunological Characterization of Arginine Kinase from the Indianmeal Moth, Plodia interpunctella, a Novel Cross-Reactive Invertebrate Pan-Allergen1

  2001cited by this paper
• Comparison of immediate intradermal test reactivity with serum IgE quantitation by use of a radioallergosorbent test and two ELISA in horses with and without atopy.

  2001cited by this paper
• Allergen-specific IgE levels against crude mould and storage mite extracts and recombinant mould allergens in sera from horses affected with chronic bronchitis.

  2000cited by this paper
• Nutrient Requirements and Interactions Consumption of Buckwheat Protein Lowers Plasma Cholesterol and Raises Fecal Neutral Sterols in Cholesterol-Fed Rats Because of Its Low Digestibility

  1997cited by this paper
• Quantification of histamine in plasma and pulmonary fluids from horses with chronic obstructive pulmonary disease, before and after 'natural (hay and straw) challenges'.

  1993cited by this paper
• Atopic dermatitis of the face, scalp, and neck: type I reaction to the yeast Pityrosporum ovale?

  1992cited by this paper
• Equine insect hypersensitivity: skin test and biopsy results correlated with clinical data.

  1990cited by this paper
• Intradermal challenge of Icelandic horses with extracts of four species of the genus Culicoides.

  1989cited by this paper

• Epithelial barrier dysfunction and associated diseases in companion animals: Differences and similarities between humans and animals and research needs

  2024cites this paper
• An overview of buckwheat allergy: A rare allergenic food

  2023cites this paper
• A Review on Epidemiological and Clinical Studies on Buckwheat Allergy

  2021cites this paper
• A WAO — ARIA — GA2LEN consensus document on molecular-based allergy diagnosis (PAMD@): Update 2020

  2020cites this paper
• Understanding buckwheat allergies for the management of allergic reactions in humans and animals

  2020cites this paper
• Linking cross-reactivity clusters of food and respiratory allergens in PAMD@ to asthma and duration of allergy

  2020cites this paper
• Assessment of serum allergenspecific IgE levels in horses from Siedlce County, Poland

  2020cites this paper
• The Comparison of Skin Transcriptomes Confirms Canine Atopic Dermatitis Is a Natural Homologue to the Human Disease.

  2019cites this paper
• Antigen array for serological diagnosis and novel allergen identification in severe equine asthma

  2019cites this paper
• EAACI position paper: Comparing insect hypersensitivity induced by bite, sting, inhalation or ingestion in human beings and animals

  2019cites this paper
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  2018cites this paper