Guidance of mesoderm cell migration in the Xenopus gastrula requires PDGF signaling

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Development

• Publication date

  2004-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1242/dev.01141PMID 15128658
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phosphoinositide 3-kinase is required for process outgrowth and cell polarization of gastrulating mesendodermal cells.

  2003cited by this paper
• Platelet-derived growth factor receptor alpha (pdgfr-alpha) gene in zebrafish embryonic development.

  2002cited by this paper
• Stat3 Controls Cell Movements during Zebrafish Gastrulation.

  2002cited by this paper
• Shaping the Vertebrate Body Plan by Polarized Embryonic Cell Movements

  2002cited by this paper
• Platelet-derived growth factor A (pdgf-a) expression during zebrafish embryonic development

  2002cited by this paper
• Both platelet-derived growth factor receptor (PDGFR)-alpha and PDGFR-beta promote murine fibroblast cell migration.

  2001cited by this paper
• Frizzled-7 signalling controls tissue separation during Xenopus gastrulation

  2001cited by this paper
• Developmental roles of platelet‐derived growth factors

  2001cited by this paper
• Guidance of cell migration by the Drosophila PDGF/VEGF receptor.

  2001cited by this paper
• PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor.

  2001influential reference
• Both Platelet-Derived Growth Factor Receptor (PDGFR)-α and PDGFR-β Promote Murine Fibroblast Cell Migration

  2001cited by this paper
• PDGF-D is a specific, protease-activated ligand for the PDGF β-receptor

  2001influential reference
• Mechanisms of platelet‐derived growth factor–induced chemotaxis

  2001cited by this paper
• PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor.

  2000influential reference
• Insights into extracellular matrix functions from mutant mouse models.

  2000cited by this paper
• Traditional Retailer’s Pricing Strategy in the face of Online Competition - A Microeconomic Analysis

  2000cited by this paper
• Integrin and ECM functions: roles in vertebrate development.

  2000cited by this paper
• PDGF-C is a new protease-activated ligand for the PDGF α-receptor

  2000influential reference
• Vegetal rotation, a new gastrulation movement involved in the internalization of the mesoderm and endoderm in Xenopus.

  1999cited by this paper
• Mechanism of action and in vivo role of platelet-derived growth factor.

  1999cited by this paper
• Identification of the Receptor-associated Signaling Enzymes That Are Required for Platelet-derived Growth Factor-AA-dependent Chemotaxis and DNA Synthesis*

  1999cited by this paper
• Overactivation of Phospholipase C-γ1 Renders Platelet-derived Growth Factor β-Receptor-expressing Cells Independent of the Phosphatidylinositol 3-Kinase Pathway for Chemotaxis*

  1999cited by this paper
• Establishment of substratum polarity in the blastocoel roof of the Xenopus embryo.

  1999cited by this paper
• Patterns and control of cell motility in the Xenopus gastrula.

  1998cited by this paper
• Conditions for fibronectin fibril formation in the early Xenopus embryo

  1998cited by this paper
• The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites.

  1997cited by this paper
• Phosphorylation site-specific inhibition of platelet-derived growth factor beta-receptor autophosphorylation by the receptor blocking tyrphostin AG1296.

  1997cited by this paper
• Distribution and functions of platelet-derived growth factors and their receptors during embryogenesis.

  1997cited by this paper
• Mutation of a Src phosphorylation site in the PDGF beta‐receptor leads to increased PDGF‐stimulated chemotaxis but decreased mitogenesis.

  1996cited by this paper
• Xenopus embryonic cell adhesion to fibronectin: position-specific activation of RGD/synergy site-dependent migratory behavior at gastrulation

  1996cited by this paper
• Fibronectin, mesoderm migration, and gastrulation in Xenopus.

  1996influential reference
• PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis.

  1996cited by this paper
• Embryonic mesoderm cells spread in response to platelet-derived growth factor and signaling by phosphatidylinositol 3-kinase.

  1996influential reference
• Normal table of Xenopus laevis (Daudin)

  1995cited by this paper
• PDGF signalling is required for gastrulation of Xenopus laevis.

  1995influential reference
• Differential chemotactic responses mediated by platelet-derived growth factor alpha- and beta-receptors.

  1995cited by this paper
• Vertical versus planar neural induction in Rana pipiens embryos.

  1994cited by this paper
• Characterization of the retention motif in the C-terminal part of the long splice form of platelet-derived growth factor A-chain.

  1994cited by this paper
• Localization of PDGF A and PDGFRα mRNA in Xenopus embryos suggests signalling from neural ectoderm and pharyngeal endoderm to neural crest cells

  1994cited by this paper
• Mesoderm cell migration in the vertebrate gastrula

  1994cited by this paper
• Regulation of chemotaxis by the platelet-derived growth factor receptor-β

  1994cited by this paper
• Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes.

  1994cited by this paper
• The Xenopus platelet-derived growth factor alpha receptor: cDNA cloning and demonstration that mesoderm induction establishes the lineage-specific pattern of ligand and receptor gene expression.

  1993cited by this paper
• Involvement of fibronectin during epiboly and gastrulation in embryos of the common carp, Cyprinus carpio

  1993cited by this paper
• Microinjection of antifibronectin antibodies in the chicken blastoderm: Inhibition of mesoblast cell migration but not of cell ingression at the primitive streak

  1993cited by this paper
• Compartmentalization of PDGF on extracellular binding sites dependent on exon-6-encoded sequences

  1992cited by this paper
• Developmental expression of the alpha receptor for platelet-derived growth factor, which is deleted in the embryonic lethal Patch mutation.

  1992cited by this paper
• Platelet-derived growth factor-A and its receptor are expressed in separate, but adjacent cell layers of the mouse embryo.

  1992cited by this paper
• Cell interaction and its role in mesoderm cell migration during Xenopus gastrulation

  1992influential reference
• Motile behavior and protrusive activity of migratory mesoderm cells from the Xenopus gastrula.

  1992cited by this paper
• Expression of mouse PDGF-A and PDGF alpha-receptor genes during pre- and post-implantation development: evidence for a developmental shift from an autocrine to a paracrine mode of action.

  1992cited by this paper
• Directional mesoderm cell migration in the Xenopus gastrula.

  1991influential reference
• Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid.

  1991cited by this paper
• In situ hybridization: an improved whole-mount method for Xenopus embryos.

  1991cited by this paper
• Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation.

  1991cited by this paper
• Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction.

  1991cited by this paper
• Mouse platelet-derived growth factor receptor alpha gene is deleted in W19H and patch mutations on chromosome 5.

  1991cited by this paper
• Relative platelet-derived growth factor receptor subunit expression determines cell migration to different dimeric forms of PDGF.

  1990cited by this paper
• In vivo analyses of integrin beta 1 subunit function in fibronectin matrix assembly

  1990cited by this paper
• Mesodermal cell migration during Xenopus gastrulation.

  1990cited by this paper
• Dominant-negative mutants of a platelet-derived growth factor gene.

  1990cited by this paper
• Mesoderm induction and the control of gastrulation in Xenopus laevis: the roles of fibronectin and integrins.

  1990cited by this paper
• B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase.

  1990cited by this paper
• Both homodimeric isoforms of PDGF (AA and BB) have mitogenic and chemotactic activity and stimulate phosphoinositol turnover

  1989cited by this paper
• Platelet-derived growth factor A chain is maternally encoded in Xenopus embryos.

  1988cited by this paper
• Prevention of gastrulation but not neurulation by antibodies to fibronectin in amphibian embryos

  1984cited by this paper
• Comparative study of extracellular fibrils on the ectodermal layer in gastrulae of five amphibian species.

  1983cited by this paper
• Conditioning of a culture substratum by the ectodermal layer promotes attachment and oriented locomotion by amphibian gastrula mesodermal cells.

  1983cited by this paper
• Xenopus laevis Daudin

  1971cited by this paper
• Principles of Cell Motility: The Direction of Cell Movement and Cancer Invasion

  1965cited by this paper
• Mouse platelet-derived growth factor receptor a gene is deleted in WJ 9 H and patch mutations on chromosome 5

  year unknowncited by this paper

• Neural Crest Migration Orchestrated by Molecular and Mechanical Signals.

  2025cites this paper
• Regulation of epithelial cell jamming transition by cytoskeleton and cell-cell interactions.

  2024cites this paper
• Modeling the roles of cohesotaxis, cell-intercalation, and tissue geometry in collective cell migration of Xenopus mesendoderm

  2024cites this paper
• Extracellular matrix-derived materials for tissue engineering and regenerative medicine: A journey from isolation to characterization and application

  2024cites this paper
• Functional characterization of the dimeric form of PDGF-derived fusion peptide fabricated based on theoretical arguments

  2024cites this paper
• Polarized contact behavior in directionally migrating Xenopus gastrula mesendoderm.

  2023cites this paper
• The evolution of gastrulation morphologies

  2023cites this paper
• Modeling the roles of cohesotaxis, cell-intercalation, and tissue geometry in collective cell migration of Xenopus mesendoderm

  2023cites this paper
• Microsurgical Manipulations to Isolate Collectively Migrating Mesendoderm.

  2022cites this paper
• Rapalog‐induced cell adhesion molecule inhibits mesoderm migration in Xenopus embryos by increasing frequency of adhesion to the ectoderm

  2022cites this paper
• BRCA1 and ELK-1 regulate neural progenitor cell fate in the optic tectum in response to visual experience in Xenopus laevis tadpoles

  2021cites this paper
• Capillarity and active cell movement at mesendoderm translocation in the Xenopus gastrula.

  2021influential citation
• Molecular similarity between the mechanisms of epithelial fusion and fetal wound healing during the closure of the caudal neural tube in mouse embryos

  2021cites this paper
• Imaging of dynamic actin remodeling reveals distinct behaviors of head and trunk mesoderm in gastrulating Xenopus laevis

  2021cites this paper
• Biomaterials for Bioprinting Microvasculature.

  2020cites this paper
• Pcdh18a regulates endocytosis of E-cadherin during axial mesoderm development in zebrafish

  2020cites this paper
• Mesoderm and endoderm internalization in the Xenopus gastrula.

  2020cites this paper
• A 3D Microfabricated Scaffold System for Unidirectional Cell Migration

  2020cites this paper
• A deficiency in SUMOylation activity disrupts multiple pathways leading to neural tube and heart defects in Xenopus embryos

  2019cites this paper
• The Physical and Biochemical Properties of the Extracellular Matrix Regulate Cell Fate.

  2018cites this paper
• Intracellular calcium signal at the leading edge regulates mesodermal sheet migration during Xenopus gastrulation

  2018cites this paper
• Cell migration in the Xenopus gastrula

  2018cites this paper
• PDGF-A suppresses contact inhibition during directional collective cell migration

  2018influential citation
• Amphibian Zic Genes.

  2018cites this paper
• Integrin and ligand-independent PDGFr signaling synergistically contribute to directional migration of Xenopus mesendoderm

  2018influential citation
• Characterization of convergent thickening, a major convergence force producing morphogenic movement in amphibians

  2018cites this paper
• Post-Turing tissue pattern formation: Advent of mechanochemistry

  2018cites this paper
• PDGF controls contact inhibition of locomotion by regulating N-cadherin during neural crest migration

  2017influential citation
• Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing.

  2017cites this paper
• Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly

  2017cites this paper
• Identification of human exercise-induced physiological function changes based on bioinformatics analysis.

  2016cites this paper
• Live Imaging of Axolotl Digit Regeneration Reveals Spatiotemporal Choreography of Diverse Connective Tissue Progenitor Pools

  2016cites this paper
• Collective cell migration in development

  2016influential citation
• Platelet-Derived Growth Factor in the Ovarian Follicle Attracts the Stromal Cells of the Fallopian Tube Fimbriae

  2016cites this paper
• PDGF signaling directs cardiomyocyte movement toward the midline during heart tube assembly

  2016cites this paper
• Newly uncovered novel properties of heparanase in the heart and pancreas

  2016cites this paper
• Studying early stages of fibronectin fibrillogenesis in living cells by atomic force microscopy.

  2015cites this paper
• Studying early stages of fibronectin fibrillogenesis in living cells by atomic force microscopy

  2015cites this paper
• Investigating Mechanical Interactions of Cells with Their Environment

  2015cites this paper
• Cell migration: from tissue culture to embryos

  2014cites this paper
• Combination of in ovo electroporation and time‐lapse imaging to study migrational events in chicken embryos

  2014cites this paper
• Growth factors and early mesoderm morphogenesis: Insights from the sea urchin embryo

  2014influential citation
• Identification of Pax3 and Zic1 targets in the developing neural crest.

  2014cites this paper
• Characterization of Platelet-Derived Growth Factor-A Expression in Mouse Tissues Using a lacZ Knock-In Approach

  2014cites this paper
• A PDGFRalpha perspective on PDGF signalling in developmental and pathological processes

  2014cites this paper
• The Role of Sumoylation in Early Development of Xenopus laevis and Regulation of 5S Ribosomal RNA Genes

  2014cites this paper
• A Molecular Analysis of Skeletal Morphogenesis in the Sea Urchin Embryo

  2013cites this paper
• Directional migration of leading-edge mesoderm generates physical forces: Implication in Xenopus notochord formation during gastrulation.

  2013cites this paper
• Differential gene expression profile of first-generation and second-generation rapamycin-resistant allogeneic T cells.

  2013cites this paper
• Growth factor-mediated mesodermal cell guidance and skeletogenesis during sea urchin gastrulation

  2013cites this paper
• Integrated cellular biophysical migration approach

  2013cites this paper
• Extracellular Matrix Functions in Amphibian Gastrulation

  2013cites this paper
• Investigating the Role of Apelin Receptor Signaling in Zebrafish Myocardial Progenitor Development

  2013cites this paper
• Pdgfra protects against ethanol-induced craniofacial defects in a zebrafish model of FASD

  2013cites this paper
• RNA species whose transcription is totally silent in pre-MBT stage are not mRNA but rRNA and possible involvement of weak bases (ammonium salts and/or amines) in the transcriptional silence of rRNA genes during the pre-MBT stage in Xenopus early embryos

  2013cites this paper
• Interactions between undifferentiated and osteogenically differentiated mesenchymal stromal cells during osteogenesis

  2013cites this paper
• Expression of xSDF-1α, xCXCR4, and xCXCR7 during gastrulation in Xenopus laevis.

  2013cites this paper
• Convergent extension: using collective cell migration and cell intercalation to shape embryos

  2012cites this paper
• Cadherin function during Xenopus gastrulation.

  2012cites this paper
• Cell migration.

  2012cites this paper
• Proteomic analysis of differences in ectoderm and mesoderm membranes by DiGE.

  2012cites this paper
• Analyzing the Function of PTK7 in Cell Migration

  2012influential citation
• Collective mesendoderm migration relies on an intrinsic directionality signal transmitted through cell contacts

  2012cites this paper
• A mechanoresponsive cadherin-keratin complex directs polarized protrusive behavior and collective cell migration.

  2012cites this paper
• The cytoplasmic tyrosine kinase Arg regulates gastrulation via control of actin organization.

  2012cites this paper
• Collective Epithelial and Mesenchymal Cell Migration During Gastrulation

  2012cites this paper
• EphrinB/EphB Signaling Controls Embryonic Germ Layer Separation by Contact-Induced Cell Detachment

  2011cites this paper
• PDGF-A controls mesoderm cell orientation and radial intercalation during Xenopus gastrulation

  2011influential citation
• Fibronectins, their fibrillogenesis, and in vivo functions.

  2011cites this paper
• Chemokine ligand Xenopus CXCLC (XCXCLC) regulates cell movements during early morphogenesis

  2011cites this paper
• Mesoderm layer formation in Xenopus and Drosophila gastrulation

  2011cites this paper
• A Systems Level Analysis of the Transcription Factor FoxN2/3 and FGF Signal Transduction in Sea Urchin Larval Skeleton Development and Body Axis Formation

  2011cites this paper
• Sweet cues

  2010cites this paper
• The role of N-cadherin and S1P/S1P1 in pancreas development

  2010cites this paper
• Advances in Computational Systems Biology

  2010cites this paper
• Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway

  2010influential citation
• Coordination of Hox identity between germlayers along the anterior-to-posterior axisof the vertebrate embryo

  2010cites this paper
• Development of Diverse Tools for Pigment Cell Research and Drug Screening in Zebrafish

  2010cites this paper
• Cell migration during morphogenesis.

  2010cites this paper
• The extracellular matrix in development and morphogenesis: a dynamic view.

  2010cites this paper
• 1 ADVANCES IN COMPUTATIONAL SYSTEMS BIOLOGY

  2009cites this paper
• Cell adhesion in amphibian gastrulation.

  2009cites this paper
• Role of p21‐activated kinase in cell polarity and directional mesendoderm migration in the Xenopus gastrula

  2009cites this paper
• Paxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration.

  2009cites this paper
• Trafficking and Cell Migration

  2009cites this paper
• Regulation of cell migration during chick gastrulation.

  2009cites this paper
• Collective cell migration in development

  2009cites this paper
• PDGF-A interactions with fibronectin reveal a critical role for heparan sulfate in directed cell migration during Xenopus gastrulation

  2009influential citation
• BMC Systems Biology

  2009cites this paper
• CHAPTER 1 ADVANCES IN COMPUTATIONAL SYSTEMS BIOLOGY

  2009cites this paper
• Gene Expression in Pre-MBT Embryos and Activation of Maternally-Inherited Program of Apoptosis to be Executed at around MBT as a Fail-Safe Mechanism in Xenopus Early Embryogenesis

  2008cites this paper
• Disruption of PDGFRα-initiated PI3K activation and migration of somite derivatives leads to spina bifida

  2008cites this paper
• Sphingosine-1-phosphate receptors regulate individual cell behaviours underlying the directed migration of prechordal plate progenitor cells during zebrafish gastrulation

  2008cites this paper
• Deciphering animal development through proteomics: requirements and prospects

  2008cites this paper
• Chemokine Signaling in Amphibian Gastrulation

  2008cites this paper
• Modular control of endothelial sheet migration.

  2008cites this paper
• An investigation into the genes mediating myoblast migration in the nematode : Caenorhabditis elegans

  2008cites this paper
• Role of platelet-derived growth factors in physiology and medicine.

  2008influential citation
• PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression

  2008cites this paper
• MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis

  2008cites this paper