Subacute administration of fluoxetine prevents short-term brain hypometabolism and reduces brain damage markers induced by the lithium-pilocarpine model of epilepsy in rats.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Brain Research Bulletin

• Publication date

  2015-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.brainresbull.2014.12.009PMID 25541342
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In Vivo [18F] FDG PET Imaging Reveals that p-Chloroamphetamine Neurotoxicity is Associated with Long-Term Cortical and Hippocampal Hypometabolism

  2015cited by this paper
• Fluoxetine Pretreatment Promotes Neuronal Survival and Maturation after Auditory Fear Conditioning in the Rat Amygdala

  2014cited by this paper
• A pilot study in epilepsy patients using simultaneous PET/MR.

  2014cited by this paper
• Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects.

  2014cited by this paper
• Are alterations in transmitter receptor and ion channel expression responsible for epilepsies?

  2014cited by this paper
• Chronic intermittent hypoxic preconditioning suppresses pilocarpine-induced seizures and associated hippocampal neurodegeneration.

  2014cited by this paper
• Effects of oxygen insufflation during pilocarpine-induced status epilepticus on mortality, tissue damage and seizures.

  2014cited by this paper
• Towards a reproducible protocol for repetitive and semi-quantitative rat brain imaging with 18 F-FDG: Exemplified in a memantine pharmacological challenge

  2014cited by this paper
• Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid

  2013cited by this paper
• The Role of Radionuclide Imaging in Epilepsy, Part 1: Sporadic Temporal and Extratemporal Lobe Epilepsy

  2013cited by this paper
• Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death

  2013cited by this paper
• Experimental Models of Status Epilepticus and Neuronal Injury for Evaluation of Therapeutic Interventions

  2013cited by this paper
• Comparison of Ca2+ transients and [Ca2+]i in the dendrites and boutons of non‐fast‐spiking GABAergic hippocampal interneurons using two‐photon laser microscopy and high‐ and low‐affinity dyes

  2013cited by this paper
• Reciprocal Modulation Between Microglia and Astrocyte in Reactive Gliosis Following the CNS Injury

  2013cited by this paper
• FDG-PET imaging in mild traumatic brain injury: a critical review

  2013cited by this paper
• Fluoxetine-Induced Cortical Adult Neurogenesis

  2013cited by this paper
• Neuronal circuits in epilepsy: do they matter?

  2013cited by this paper
• The role of radionuclide imaging in epilepsy, Part 1: Sporadic temporal and extratemporal lobe epilepsy.

  2013cited by this paper
• Should antidepressant drugs of the selective serotonin reuptake inhibitor family be tested as antiepileptic drugs?

  2013cited by this paper
• Role of nonsynaptic GluN2B-containing NMDA receptors in excitotoxicity: evidence that fluoxetine selectively inhibits these receptors and may have neuroprotective effects.

  2013cited by this paper
• Gabapentin Administration Reduces Reactive Gliosis and Neurodegeneration after Pilocarpine-Induced Status Epilepticus

  2013cited by this paper
• Neuronal degeneration and gliosis time-course in the mouse hippocampal formation after pilocarpine-induced status epilepticus.

  2012cited by this paper
• Applications of positron emission tomography in animal models of neurological and neuropsychiatric disorders.

  2012cited by this paper
• Modeling the glutamate–glutamine neurotransmitter cycle

  2012cited by this paper
• Hypophagia and induction of serotonin transporter gene expression in raphe nuclei of male and female rats after short-term fluoxetine treatment

  2012cited by this paper
• The antidepressant sertraline prevents the behavioral and EEG changes induced in two animal models of seizures.

  2012cited by this paper
• Hypometabolism precedes limbic atrophy and spontaneous recurrent seizures in a rat model of TLE

  2012cited by this paper
• Reduced Astrocytic Contribution to the Turnover of Glutamate, Glutamine, and GABA Characterizes the Latent Phase in the Kainate Model of Temporal Lobe Epilepsy

  2011cited by this paper
• Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs.

  2011cited by this paper
• Novel Control by the CA3 Region of the Hippocampus on Neurogenesis in the Dentate Gyrus of the Adult Rat

  2011cited by this paper
• The topography and significance of extratemporal hypometabolism in refractory mesial temporal lobe epilepsy examined by FDG‐PET

  2010cited by this paper
• The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity

  2010cited by this paper
• Astrogliosis in CNS Pathologies: Is There A Role for Microglia?

  2010cited by this paper
• Oxidative stress mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus.

  2010cited by this paper
• Up-regulation of d-serine Might Induce GABAergic Neuronal Degeneration in the Cerebral Cortex and Hippocampus in the Mouse Pilocarpine Model of Epilepsy

  2009cited by this paper
• Glucocorticoid Receptor Antagonism Augments Fluoxetine-Induced Downregulation of the 5-HT Transporter

  2009cited by this paper
• Longitudinal microPET imaging of brain glucose metabolism in rat lithium-pilocarpine model of epilepsy.

  2009cited by this paper
• Pentylenetetrazole-induced seizures affect binding site densities for GABA, glutamate and adenosine receptors in the rat brain.

  2009cited by this paper
• In vivo mapping of temporospatial changes in glucose utilization in rat brain during epileptogenesis: an 18F-fluorodeoxyglucose-small animal positron emission tomography study.

  2009cited by this paper
• Time-course of neuronal death in the mouse pilocarpine model of chronic epilepsy using Fluoro-Jade C staining.

  2008cited by this paper
• Chronic Fluoxetine Stimulates Maturation and Synaptic Plasticity of Adult-Born Hippocampal Granule Cells

  2008cited by this paper
• Application of Coregistration for Imaging of Animal Models of Epilepsy

  2007cited by this paper
• Imaging small animal models of epileptogenesis

  2007cited by this paper
• Ca2+ channel α2δ ligands: novel modulators of neurotransmission

  2007cited by this paper
• Serotonin and epilepsy

  2007cited by this paper
• Ca2+ channel alpha2delta ligands: novel modulators of neurotransmission.

  2007cited by this paper
• Pathogenesis and Pharmacology of Epilepsy in the Lithium‐pilocarpine Model

  2007cited by this paper
• Status Epilepticus Triggers Caspase‐3 Activation and Necrosis in the Immature Rat Brain

  2007cited by this paper
• Increase in neurogenesis and behavioural benefit after chronic fluoxetine treatment in Wistar rats

  2007cited by this paper
• Developmental Cell Death Is Enhanced in the Cerebral Cortex of Mice Lacking the Brain Vesicular Monoamine Transporter

  2007cited by this paper
• Animal models for the development of new neuropharmacological therapeutics in the status epilepticus.

  2006cited by this paper
• Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus.

  2006cited by this paper
• Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons.

  2005cited by this paper
• The serotonergic and noradrenergic effects of antidepressant drugs are anticonvulsant, not proconvulsant.

  2005cited by this paper
• Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines.

  2004cited by this paper
• ILAE Commission Report. Mesial temporal lobe epilepsy with hippocampal sclerosis.

  2004cited by this paper
• Effects of electroconvulsive seizures and antidepressant drugs on brain-derived neurotrophic factor protein in rat brain.

  2003cited by this paper
• The epidemiology of epilepsy revisited

  2003cited by this paper
• Fluoxetine depresses glutamate exocytosis in the rat cerebrocortical nerve terminals (synaptosomes) via inhibition of P/Q‐type Ca2+ channels

  2003cited by this paper
• The anticonvulsant effect of citalopram as an indirect evidence of serotonergic impairment in human epileptogenesis.

  2003cited by this paper
• Pilocarpine-induced status epilepticus results in mossy fiber sprouting and spontaneous seizures in C57BL/6 and CD-1 mice.

  2002cited by this paper
• Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice

  2002cited by this paper
• Effects of Fluoxetine and TFMPP on Spontaneous Seizures in Rats with Pilocarpine‐induced Epilepsy

  2002cited by this paper
• Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus

  2000cited by this paper
• Effects of Gabapentin on Brain GABA, Homocarnosine, and Pyrrolidinone in Epilepsy Patients

  2000cited by this paper
• Changes in [3H]zolpidem and [3H]Ro 15-1788 binding in rat globus pallidus and substantia nigra pars reticulata following a nigrostriatal tract lesion.

  2000cited by this paper
• Reactive astrocytes: cellular and molecular cues to biological function.

  1997cited by this paper
• Serotonin promotes the survival of cortical glutamatergic neurons in vitro.

  1997cited by this paper
• Prolonged but not acute fluoxetine administration produces its inhibitory effect on hippocampal seizures in rats

  1995cited by this paper
• Lithium-pilocarpine neurotoxicity: a potential model of status epilepticus.

  1995cited by this paper
• Reactive microglia in hippocampal sclerosis associated with human temporal lobe epilepsy.

  1995cited by this paper
• Circuit Mechanisms of Seizures in the Pilocarpine Model of Chronic Epilepsy: Cell Loss and Mossy Fiber Sprouting

  1993cited by this paper
• Chronic fluoxetine treatment upregulates 5‐HT uptake sites and 5‐HT2 receptors in rat brain: An autoradiographic study

  1993cited by this paper
• Morphological changes in the dentate gyrus in human temporal lobe epilepsy.

  1992cited by this paper
• Morphological changes in the dentate gyrus in human temporal lobe epilepsy.

  1992cited by this paper
• Systemic cholinergic agents induce seizures and brain damage in lithium-treated rats.

  1983cited by this paper
• Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study.

  1983cited by this paper
• Modification of seizure activity by electrical stimulation. II. Motor seizure.

  1972cited by this paper
• Anticonvulsant compounds and 5-hydroxytryptamine in rat brain.

  1957cited by this paper

• Preclinical PET imaging in epileptogenesis: towards identification of biomarkers and therapeutic targets

  2025cites this paper
• PET imaging identifies anti-inflammatory effects of fluoxetine and a correlation of glucose metabolism during epileptogenesis with chronic seizure frequency.

  2024influential citation
• Astrocytic Ca2+ activation by chemogenetics mitigates the effect of kainic acid‐induced excitotoxicity on the hippocampus

  2024cites this paper
• The vasodilator naftidrofuryl attenuates short-term brain glucose hypometabolism in the lithium-pilocarpine rat model of status epilepticus without providing neuroprotection.

  2022cites this paper
• Vortioxetine suppresses epileptiform activity and cognition deficits in a chronic PTZ-induced kindling rat model.

  2021cites this paper
• Choice of anesthesia and data analysis method strongly increases sensitivity of 18F-FDG PET imaging during experimental epileptogenesis

  2021cites this paper
• Modulation of Glucose Availability and Effects of Hypo- and Hyperglycemia on Status Epilepticus: What We Do Not Know Yet?

  2020cites this paper
• Zinc‐α2‐glycoprotein relieved seizure‐Induced neuronal glucose uptake impairment via insulin‐like growth factor 1 receptor‐regulated glucose transporter 3 expression

  2020cites this paper
• Cerebral blood flow and oxygenation in rat brain after soman exposure.

  2020cites this paper
• Raloxifene Potentiates The Effect Of Fluoxetine Against Maximal Electroshock Induced Seizures In Mice.

  2020cites this paper
• PET Neuroimaging Reveals Serotonergic and Metabolic Dysfunctions in the Hippocampal Electrical Kindling Model of Epileptogenesis.

  2019cites this paper
• The effect of serotonin on penicillin-induced epileptiform activity

  2019cites this paper
• Neuroimaging Biomarkers of Experimental Epileptogenesis and Refractory Epilepsy

  2019cites this paper
• The effect of fluoxetine on penicillin-induced epileptiform activity.

  2019cites this paper
• Hydrogen Alleviates Necroptosis and Cognitive Deficits in Lithium–Pilocarpine Model of Status Epilepticus

  2019cites this paper
• Trazodone increases seizures in a genetic WAG/Rij rat model of absence epilepsy while decreasing them in penicillin-evoked focal seizure model.

  2019cites this paper
• Fluoxetine contamination in Dietary/Nutritional Supplements (un)bridges the quality of life for the youth to the elderly consumer.

  2018influential citation
• Metyrapone prevents acute glucose hypermetabolism and short‐term brain damage induced by intrahippocampal administration of 4‐aminopyridine in rats

  2018cites this paper
• Divergent metabolic substrate utilization in brain during epileptogenesis precedes chronic hypometabolism

  2018cites this paper
• The Synergistic Effect of Raloxifene, Fluoxetine, and Bromocriptine Protects Against Pilocarpine-Induced Status Epilepticus and Temporal Lobe Epilepsy

  2018cites this paper
• Decreased levels of active uPA and KLK8 assessed by [111In]MICA‐401 binding correlate with the seizure burden in an animal model of temporal lobe epilepsy

  2017cites this paper
• Subacute Fluoxetine Reduces Signs of Hippocampal Damage Induced by a Single Convulsant Dose of 4-Aminopyridine in Rats.

  2017cites this paper
• Interactions between GHRH and GABAARs in the brains of patients with epilepsy and in animal models of epilepsy

  2017cites this paper
• Novel insights into the effect of paroxetine administration in pilocarpine‑induced chronic epileptic rats.

  2017cites this paper
• Neuroimaging in animal models of epilepsy.

  2017cites this paper
• Metyrapone prevents brain damage induced by status epilepticus in the rat lithium‐pilocarpine model

  2017influential citation
• Serotonin receptor antagonists increase fast ripple activity in rats treated with kainic acid.

  2016cites this paper
• [18F]FDG PET Neuroimaging Predicts Pentylenetetrazole (PTZ) Kindling Outcome in Rats

  2016cites this paper
• The anti-inflammatory activity of duloxetine, a serotonin/norepinephrine reuptake inhibitor, prevents kainic acid-induced hippocampal neuronal death in mice.

  2015cites this paper
• Serotonin Depletion Does not Modify the Short-Term Brain Hypometabolism and Hippocampal Neurodegeneration Induced by the Lithium–Pilocarpine Model of Status Epilepticus in Rats

  2015cites this paper