Rotigaptide protects the myocardium and arterial vasculature from ischaemia reperfusion injury.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  British Journal of Clinical Pharmacology

• Publication date

  2016-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/bcp.12882PMID 26750458PMCID PMC4876181
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Rotigaptide protects the myocardium and arterial vasculature from ischaemia reperfusion injury.

  2016cited by this paper
• A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery.

  2015cited by this paper
• Remote Ischemic Preconditioning and Outcomes of Cardiac Surgery.

  2015cited by this paper
• The antiarrhythmic dipeptide ZP1609 (danegaptide) when given at reperfusion reduces myocardial infarct size in pigs

  2013cited by this paper
• Roles of connexins in atherosclerosis and ischemia-reperfusion injury.

  2012cited by this paper
• Novel molecular targets for atrial fibrillation therapy

  2012cited by this paper
• Ischaemia–reperfusion injury impairs tissue plasminogen activator release in man

  2011cited by this paper
• Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomised trial.

  2010cited by this paper
• Mitochondrial connexin43 as a new player in the pathophysiology of myocardial ischaemia-reperfusion injury.

  2008cited by this paper
• The vascular effects of rotigaptide in vivo in man.

  2008cited by this paper
• Connexin 43 mediates endothelium-derived hyperpolarizing factor-induced vasodilatation in subcutaneous resistance arteries from healthy pregnant women.

  2007cited by this paper
• Myocardial reperfusion injury.

  2007cited by this paper
• The antiarrhythmic peptide rotigaptide (ZP123) increases gap junction intercellular communication in cardiac myocytes and HeLa cells expressing connexin 43

  2006cited by this paper
• Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123).

  2006cited by this paper
• Treatment With the Gap Junction Modifier Rotigaptide (ZP123) Reduces Infarct Size in Rats With Chronic Myocardial Infarction

  2006cited by this paper
• Rotigaptide (ZP123) Prevents Spontaneous Ventricular Arrhythmias and Reduces Infarct Size During Myocardial Ischemia/Reperfusion Injury in Open-Chest Dogs

  2006cited by this paper
• The Antiarrhythmic Peptide Analog ZP123 Prevents Atrial Conduction Slowing During Metabolic Stress

  2005cited by this paper
• Connexin 43 and ischemic preconditioning.

  2004cited by this paper
• Myocardial Reperfusion Injury

  2004cited by this paper
• The effects of connexin phosphorylation on gap junctional communication.

  2004cited by this paper
• Pharmacological Modulation of Cardiac Gap Junctions to Enhance Cardiac Conduction: Evidence Supporting a Novel Target for Antiarrhythmic Therapy

  2003cited by this paper
• Transient limb ischemia induces remote ischemic preconditioning in vivo.

  2003cited by this paper
• Transient Limb Ischemia Induces Remote Ischemic Preconditioning In Vivo

  2002cited by this paper
• Ischemic preconditioning prevents endothelial injury and systemic neutrophil activation during ischemia-reperfusion in humans in vivo.

  2001cited by this paper
• Involvement of tyrosine kinase in the hypoxia/reoxygenation‐induced gap junctional intercellular communication abnormality in cultured human umbilical vein endothelial cells

  1999cited by this paper
• Endothelial dysfunction, impaired endogenous fibrinolysis, and cigarette smoking: a mechanism for arterial thrombosis and myocardial infarction.

  1999cited by this paper
• Connexin-43 Hemichannels Opened by Metabolic Inhibition*

  1999cited by this paper
• Characterization of gap junction channels in adult rabbit atrial and ventricular myocardium.

  1997cited by this paper
• Intra-arterial substance P mediated vasodilatation in the human forearm: pharmacology, reproducibility and tolerability.

  1997cited by this paper
• Restoration of endothelium-dependent vasodilation after reperfusion injury by tetrahydrobiopterin.

  1996cited by this paper
• PH regulation of connexin43: molecular analysis of the gating particle.

  1996cited by this paper

• Assessment of coronary endothelial dysfunction using contemporary coronary function testing.

  2024cites this paper
• Spontaneous Repolarization Alternans Causes VT/VF Rearrest That Is Suppressed by Preserving Gap Junctions

  2024cites this paper
• Gap junction modulators: Prospects in bupropion cardiotoxicity

  2024cites this paper
• Connexins in endothelial cells as a therapeutic target for solid organ transplantation

  2022cites this paper
• No sex-related differences in infarct size, no-reflow and protection by ischaemic preconditioning in Göttingen minipigs.

  2022cites this paper
• Connexins in the Heart: Regulation, Function and Involvement in Cardiac Disease

  2021cites this paper
• Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection

  2020cites this paper
• Intercellular Communication in the Heart: Therapeutic Opportunities for Cardiac Ischemia.

  2020cites this paper
• Astroglial connexins in epileptogenesis.

  2020cites this paper
• Occurrence of the d-Proline Chemotype in Enzyme Inhibitors

  2019cites this paper
• Translational Models of Arrhythmia Mechanisms and Susceptibility: Success and Challenges of Modeling Human Disease

  2019cites this paper
• Evaluating Novel Targets of Ischemia Reperfusion Injury in Pig Models

  2019cites this paper
• Therapeutic strategies targeting connexins

  2018cites this paper
• Role of Non-Myocyte Gap Junctions and Connexin Hemichannels in Cardiovascular Health and Disease: Novel Therapeutic Targets?

  2018cites this paper
• Effects of Rotigaptide and RIC on Ischemia Reperfusion Injury in the In Vitro Rabbit Heart

  2017cites this paper
• Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications

  2017cites this paper
• The gap junction modifier ZP1609 decreases cardiomyocyte hypercontracture following ischaemia/reperfusion independent from mitochondrial connexin 43

  2017cites this paper
• Rotigaptide protects the myocardium and arterial vasculature from ischaemia reperfusion injury.

  2016cites this paper