Current strategies for subunit and genetic viral veterinary vaccine development.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Virus Research

• Publication date

  2011-04-01

• Fields of study

  Agricultural and Food Sciences, Medicine, Biology

• Identifiers
  DOI 10.1016/j.virusres.2011.02.006PMID 21316403
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Targeting antigens to an invariant epitope of the MHC Class II DR molecule potentiates the immune response to subunit vaccines.

  2011cited by this paper
• Virus-like particles as particulate vaccines.

  2010cited by this paper
• Enhanced immunity against classical swine fever in pigs induced by prime-boost immunization using an alphavirus replicon-vectored DNA vaccine and a recombinant adenovirus.

  2010cited by this paper
• Evaluation of an enzyme-linked immunosorbent assay for detection of West Nile virus infection based on a recombinant envelope protein produced in Trichoplusia ni larvae.

  2010cited by this paper
• Humoral and in vivo cellular immunity against the raw insect-derived recombinant Leishmania infantum antigens KMPII, TRYP, LACK, and papLe22 in dogs from an endemic area.

  2010cited by this paper
• The Toll-like receptor adaptor molecule TRIF enhances DNA vaccination against classical swine fever.

  2010cited by this paper
• Immunity conferred by an experimental vaccine based on the recombinant PCV2 Cap protein expressed in Trichoplusia ni-larvae.

  2010cited by this paper
• Vaccination with DNA Plasmids Expressing Gn Coupled to C3d or Alphavirus Replicons Expressing Gn Protects Mice against Rift Valley Fever Virus

  2010cited by this paper
• Validation of a novel approach for the rapid production of immunogenic virus-like particles for bluetongue virus.

  2010cited by this paper
• Biosafety of DNA vaccines: New generation of DNA vectors and current knowledge on the fate of plasmids after injection.

  2010cited by this paper
• Induction of Long-Term Protective Immune Responses by Influenza H5N1 Virus-Like Particles

  2009cited by this paper
• Attenuated Foot-and-Mouth Disease Virus RNA Carrying a Deletion in the 3′ Noncoding Region Can Elicit Immunity in Swine

  2009cited by this paper
• Ubiquitin Conjugation of Open Reading Frame F DNA Vaccine Leads to Enhanced Cell-Mediated Immune Response and Induces Protection against Both Antimony-Susceptible and -Resistant Strains of Leishmania donovani1

  2009cited by this paper
• Enhanced immune response and protection efficacy of a DNA vaccine constructed by linkage of the Mycobacterium tuberculosis Ag85B-encoding gene with the BVP22-encoding gene.

  2009cited by this paper
• Foot-and-Mouth Disease Virus neutralizing antibodies production induced by pcDNA3 and Sindbis virus based plasmid encoding FMDV P1-2A3C3D in swine.

  2009cited by this paper
• Prime-boost immunization using alphavirus replicon and adenovirus vectored vaccines induces enhanced immune responses against classical swine fever virus in mice.

  2009cited by this paper
• Vaccination with virus-like particles protects mice from lethal infection of Rift Valley Fever Virus.

  2009cited by this paper
• Virus-Like Particles as a Vaccine Delivery System: Myths and Facts

  2009cited by this paper
• Chimeric calicivirus-like particles elicit protective anti-viral cytotoxic responses without adjuvant.

  2009cited by this paper
• Immunogenicity and protective efficacy of Semliki forest virus replicon-based DNA vaccines encoding goatpox virus structural proteins.

  2009cited by this paper
• The protective mechanisms induced by a fish rhabdovirus DNA vaccine depend on temperature.

  2009cited by this paper
• Dual DNA vaccination of rainbow trout (Oncorhynchus mykiss) against two different rhabdoviruses, VHSV and IHNV, induces specific divalent protection.

  2009cited by this paper
• DNA prime protein boost strategies protect cattle from bovine viral diarrhea virus type 2 challenge.

  2008cited by this paper
• The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells.

  2008cited by this paper
• Cross-Clade Protective Immune Responses to Influenza Viruses with H5N1 HA and NA Elicited by an Influenza Virus-Like Particle

  2008cited by this paper
• Rift Valley fever virus structural proteins: expression, characterization and assembly of recombinant proteins

  2008cited by this paper
• Enhanced Mucosal Immunoglobulin A Response and Solid Protection against Foot-and-Mouth Disease Virus Challenge Induced by a Novel Dendrimeric Peptide

  2008cited by this paper
• A bivalent influenza VLP vaccine confers complete inhibition of virus replication in lungs.

  2008cited by this paper
• Self-Assembly of the Recombinant Capsid Protein of a Swine Norovirus into Virus-Like Particles and Evaluation of Monoclonal Antibodies Cross-Reactive with a Human Strain from Genogroup II

  2008cited by this paper
• Electroporation-based DNA transfer enhances gene expression and immune responses to DNA vaccines in cattle.

  2008cited by this paper
• The coming of age of virus-like particle vaccines

  2008cited by this paper
• DNA vaccines and their applications in veterinary practice: current perspectives

  2008cited by this paper
• Multivalent HA DNA Vaccination Protects against Highly Pathogenic H5N1 Avian Influenza Infection in Chickens and Mice

  2008cited by this paper
• Recognition of nucleic acid and nucleic acid analogs by Toll-like receptors 7, 8 and 9.

  2008cited by this paper
• Achievement of avian influenza virus-like particles that could be used as a subunit vaccine against low-pathogenic avian influenza strains in ducks

  2008cited by this paper
• Elicitation of protective immune responses using a bivalent H5N1 VLP vaccine

  2008cited by this paper
• A recombinant plasmid co-expressing swine ubiquitin and the GP5 encoding-gene of porcine reproductive and respiratory syndrome virus induces protective immunity in piglets.

  2008cited by this paper
• Exploiting viral properties for the rational design of modern vaccines

  2008cited by this paper
• Immunization of DNA vaccine encoding C3d-VP1 fusion enhanced protective immune response against foot-and-mouth disease virus

  2007cited by this paper
• Development of a low-cost, insect larvae-derived recombinant subunit vaccine against RHDV.

  2007cited by this paper
• Assembly of feline calicivirus-like particle and its immunogenicity.

  2007cited by this paper
• Virus-Like Particle Vaccine Induces Protective Immunity against Homologous and Heterologous Strains of Influenza Virus

  2007cited by this paper
• Norovirus capsid protein expressed in yeast forms virus‐like particles and stimulates systemic and mucosal immunity in mice following an oral administration of raw yeast extracts

  2007cited by this paper
• Virus-like particles: flexible platforms for vaccine development

  2007cited by this paper
• More than one reason to rethink the use of peptides in vaccine design

  2007cited by this paper
• Co-delivery of plasmid-encoded cytokines modulates the immune response to a DNA vaccine delivered by in vivo electroporation.

  2007cited by this paper
• Immune and protective abilities of ubiquitinated and non-ubiquitinated pseudorabies virus glycoproteins.

  2007cited by this paper
• In vivo tissue distribution and kinetics of a pseudorabies virus plasmid DNA vaccine after intramuscular injection in swine.

  2007cited by this paper
• Influenza virus-like particles elicit broader immune responses than whole virion inactivated influenza virus or recombinant hemagglutinin.

  2007cited by this paper
• Assessment of the Protection Afforded by Triple Baculovirus Recombinant Coexpressing H5, N3, M1 Proteins Against a Homologous H5N3 Low-Pathogenicity Avian Influenza Virus Challenge in Muscovy Ducks

  2007cited by this paper
• Vaccination, immune and gene therapy based on virus-like particles against viral infections and cancer

  2007cited by this paper
• A Novel Intranasal Virus-Like Particle (VLP) Vaccine Designed to Protect against the Pandemic 1918 Influenza A Virus (H1N1)

  2007cited by this paper
• Influenza Virus Hemagglutinin and Neuraminidase, but Not the Matrix Protein, Are Required for Assembly and Budding of Plasmid-Derived Virus-Like Particles

  2007cited by this paper
• Novel Plant Virus-Based Vaccine Induces Protective Cytotoxic T-Lymphocyte-Mediated Antiviral Immunity through Dendritic Cell Maturation

  2007cited by this paper
• Immunogenicity of novel consensus-based DNA vaccines against avian influenza.

  2007cited by this paper
• Protective immune responses in guinea pigs and swine induced by a suicidal DNA vaccine of the capsid gene of swine vesicular disease virus.

  2007cited by this paper
• Limited Protection Conferred by a DNA Vaccine against a Lethal Pseudorabies Virus Infection at Day 5 Postvaccination

  2007cited by this paper
• Efficacy of particle-based DNA delivery for vaccination of sheep against FMDV.

  2006cited by this paper
• Successful oral prime-immunization with VP60 from rabbit haemorrhagic disease virus produced in transgenic plants using different fusion strategies.

  2006cited by this paper
• Type I Interferons are essential for the efficacy of replicase-based DNA vaccines.

  2006cited by this paper
• The cell-mediated immune response induced by plasmid encoding bovine herpesvirus 1 glycoprotein B is enhanced by plasmid encoding IL-12 when delivered intramuscularly or by gene gun, but not after intradermal injection.

  2006cited by this paper
• Production of biopharmaceuticals and vaccines in plants via the chloroplast genome

  2006cited by this paper
• Mucosal and systemic adjuvant activity of alphavirus replicon particles.

  2006cited by this paper
• C3d enhanced DNA vaccination induced humoral immune response to glycoprotein C of pseudorabies virus.

  2006cited by this paper
• Cytokine GM‐CSF Genetic Adjuvant Facilitates Prophylactic DNA Vaccine against Pseudorabies Virus through Enhanced Immune Responses

  2006cited by this paper
• Improved peptide vaccine strategies, creating synthetic artificial infections to maximize immune efficacy.

  2006cited by this paper
• Prime-boost immunization using DNA vaccine and recombinant Orf virus protects pigs against Pseudorabies virus (Herpes suid 1).

  2006cited by this paper
• Rectal Immunization with Rotavirus Virus-Like Particles Induces Systemic and Mucosal Humoral Immune Responses and Protects Mice against Rotavirus Infection

  2006cited by this paper
• Applications of Influenza Virosomes as a Delivery System

  2006cited by this paper
• Viral vectors for malaria vaccine development

  2006cited by this paper
• A novel recombinant virus-like particle vaccine for prevention of porcine parvovirus-induced reproductive failure.

  2006cited by this paper
• Virus-like particles: Passport to immune recognition

  2006cited by this paper
• Genetic Vaccines and Therapy

  2006cited by this paper
• Reconstituted influenza virus envelopes as an efficient carrier system for cellular delivery of small-interfering RNAs

  2006cited by this paper
• DNA vaccines in sheep: CTLA-4 mediated targeting and CpG motifs enhance immunogenicity in a DNA prime/protein boost strategy.

  2006cited by this paper
• Intercellular trafficking of the major tegument protein VP22 of bovine herpesvirus-1 and its application to improve a DNA vaccine

  2006cited by this paper
• Immune response against grouper nervous necrosis virus by vaccination of virus-like particles.

  2006cited by this paper
• Induction of a Protective Immune Response against Viral Nervous Necrosis in the European Sea Bass Dicentrarchus labrax by Using Betanodavirus Virus-Like Particles

  2006cited by this paper
• Designing dendrimers for biological applications

  2005cited by this paper
• Virus-Like Particle (VLP) Vaccine Conferred Complete Protection against a Lethal Influenza Virus Challenge

  2005cited by this paper
• Single chain antibody fragments for the selective targeting of antigens to dendritic cells.

  2005cited by this paper
• Influenza virus-like particles comprised of the HA, NA, and M1 proteins of H9N2 influenza virus induce protective immune responses in BALB/c mice.

  2005cited by this paper
• Bovine Herpesvirus 1 VP22 Enhances the Efficacy of a DNA Vaccine in Cattle

  2005cited by this paper
• Virus-Like Particle Vaccine Conferred Complete Protection Against a Lethal Influenza Virus Challenge

  2005cited by this paper
• Induction of active immune suppression by co-immunization with DNA- and protein-based vaccines.

  2005cited by this paper
• Immunization with plasmid DNA encoding a truncated, secreted form of the bovine viral diarrhea virus E2 protein elicits strong humoral and cellular immune responses.

  2005cited by this paper
• Oral immunization of rabbits with VP60 particles confers protection against rabbit hemorrhagic disease

  2005cited by this paper
• A DNA vaccine expressing the E2 protein of classical swine fever virus elicits T cell responses that can prime for rapid antibody production and confer total protection upon viral challenge.

  2005cited by this paper
• Effective protection of pigs against lethal Pseudorabies virus infection after a single injection of low-dose Sindbis-derived plasmids encoding PrV gB, gC and gD glycoproteins.

  2005cited by this paper
• In vivo electroporation improves immune responses to DNA vaccination in sheep.

  2004cited by this paper
• Immune responses of swine following DNA immunization with plasmids encoding porcine reproductive and respiratory syndrome virus ORFs 5 and 7, and porcine IL-2 and IFNgamma.

  2004cited by this paper
• Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation

  2004cited by this paper
• Influence of routes and administration parameters on antibody response of pigs following DNA vaccination.

  2004cited by this paper
• Apoptosis is essential for the increased efficacy of alphaviral replicase-based DNA vaccines.

  2004cited by this paper
• Modulation of immune responses to bovine herpesvirus‐1 in cattle by immunization with a DNA vaccine encoding glycoprotein D as a fusion protein with bovine CD154

  2004cited by this paper
• The coat protein of Rabbit hemorrhagic disease virus contains a molecular switch at the N-terminal region facing the inner surface of the capsid.

  2004cited by this paper
• Antibody responses to Brugia malayi antigens induced by DNA vaccination

  2004cited by this paper
• Targeting plasmid‐encoded proteins to the antigen presentation pathways

  2004cited by this paper
• Protective lactogenic immunity conferred by an edible peptide vaccine to bovine rotavirus produced in transgenic plants.

  2004cited by this paper
• Strategies for improved formulation and delivery of DNA vaccines to veterinary target species

  2004cited by this paper

• Development of an oral gut-targeted rabies virus-like particles (RVLPs) vaccine with mucosal immune adjuvant LTB via delivering of localized-release microparticles

  2025cites this paper
• Antibiotic Alternative Strategies Against Aeromonas hydrophila Infections: New Trends and Advances

  2025cites this paper
• Chemical Mediated Bacterial Ghost Generation of Pasteurella multocida

  2025cites this paper
• Design of Novel Vaccines Based on Virus-Like Particles.

  2024cites this paper
• Advancing novel veterinary vaccines: From comprehensive antigen and adjuvant design to preparation process optimization.

  2024cites this paper
• Screening and identification of linear B-cell epitopes on structural proteins of African Swine Fever Virus

  2024cites this paper
• Serological characterisation of Lagovirus virus-like particles originating from native and mutated VP60 of rabbit haemorrhagic disease virus 2 and European brown hare syndrome virus

  2024cites this paper
• Gelatin Micro/Nanoparticles-Based Delivery of Urease and Omp31 in Mice Has a Protective Role Against Brucella melitensis 16 M Infection

  2023cites this paper
• Spatial, Temporal, and Demographic Patterns in the Prevalence of Hemorrhagic Septicemia in 41 Countries in 2005–2019: A Systematic Analysis with Special Focus on the Potential Development of a New-Generation Vaccine

  2022cites this paper
• An Overview of Veterinary Viral Diseases and Vaccine Technologies.

  2022cites this paper
• Virus Benzeri Partiküller ve Aşıların Geliştirilmesinde Önemi

  2022cites this paper
• Nucleic acid vaccines and reverse vaccinology

  2021cites this paper
• E2-CD154 vaccine candidate is safe and immunogenic in pregnant sows, and the maternal derived neutralizing antibodies protect piglets from classical swine fever virus challenge.

  2021cites this paper
• Is it possible to ensure COVID19 vaccine supply by using plants?

  2021cites this paper
• Immunomodulatory Strategies for Parapoxvirus: Current Status and Future Approaches for the Development of Vaccines against Orf Virus Infection

  2021cites this paper
• Exosome-Based Vaccines: Pros and Cons in the World of Animal Health

  2021cites this paper
• A bivalent B-cell epitope dendrimer peptide can confer long lasting immunity in swine against foot-and-mouth disease.

  2020cites this paper
• Vitamin E Scaffolds of pH-Responsive Lipid Nanoparticles as DNA Vaccines in Cancer and Protozoan Infection.

  2020cites this paper
• Introduction to Veterinary Vaccines

  2020cites this paper
• A Single Dose of Dendrimer B2T Peptide Vaccine Partially Protects Pigs against Foot-and-Mouth Disease Virus Infection

  2020cites this paper
• Advances in novel vaccines for foot and mouth disease: focus on recombinant empty capsids

  2019cites this paper
• A Review of Fish Vaccine Development Strategies: Conventional Methods and Modern Biotechnological Approaches

  2019cites this paper
• Immune response of heterologous recombinant antigenic protein of viral hemorrhagic septicemia virus (VHSV) in mice

  2019cites this paper
• THE IMMUNE RESPONSE INDUCED BY E. COLI IN CHICKENS AND AVAILABLE VACCINES

  2018cites this paper
• Selección de probióticos inmunoestimulantes en lenguados (solea senegalensis k) frente a vibrio harveyi y photobacterium damselae subsp. Piscicida

  2018cites this paper
• Evaluation of methods for generating Senecavirus A virus-like particles utilizing the baculovirus expression vector system

  2017cites this paper
• The codon-optimized capsid gene of duck circovirus can be highly expressed in yeast and self-assemble into virus-like particles

  2017cites this paper
• Polypeptides and Engineered Proteins

  2017cites this paper
• Desarrollo de vacunas recombinantes marcadoras multiserotipo frente al virus de la lengua azul

  2017cites this paper
• Bacterial ghosts as adjuvants: mechanisms and potential

  2017cites this paper
• Cápsidas vacías del virus de la enfermedad hemorrágica del conejo como plataforma para la inducción de respuesta humoral neutralizante y protectora frente a epítopos B heterólogos

  2017cites this paper
• Generation of porcine reproductive and respiratory syndrome (PRRS) virus-like-particles (VLPs) with different protein composition.

  2016cites this paper
• Rabbit hemorrhagic disease virus capsid, a versatile platform for foreign B-cell epitope display inducing protective humoral immune responses

  2016cites this paper
• Full protection of swine against foot-and-mouth disease by a bivalent B-cell epitope dendrimer peptide.

  2016cites this paper
• Generation and immunogenicity of porcine circovirus type 2 chimeric virus-like particles displaying porcine reproductive and respiratory syndrome virus GP5 epitope B.

  2016cites this paper
• Vaccines and Vaccination for Veterinary Viral Diseases: A General Overview

  2015influential citation
• An experimental subunit vaccine based on Bluetongue virus 4 VP2 protein fused to an antigen-presenting cells single chain antibody elicits cellular and humoral immune responses in cattle, guinea pigs and IFNAR(-/-) mice.

  2015cites this paper
• SplitCore Technology Allows Efficient Production of Virus-Like Particles Presenting a Receptor-Contacting Epitope of Human IgE

  2015cites this paper
• Targeted Collection of Plasmid DNA in Large and Growing Animal Muscles 6 Weeks after DNA Vaccination with and without Electroporation

  2015cites this paper
• Expression and characterization of the gD protein of HSV-2 fused to the tetramerization domain of the transcription factor p53.

  2015cites this paper
• Plant-produced viral bovine vaccines: what happened during the last 10 years?

  2015cites this paper
• Production and Evaluation of Virus-Like Particles Displaying Immunogenic Epitopes of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

  2015cites this paper
• Plant-based porcine reproductive and respiratory syndrome virus VLPs induce an immune response in mice.

  2015cites this paper
• Therapeutic Proteins: Blood Products, Vaccines and Enzymes

  2015cites this paper
• Vaccines and Vaccination

  2015influential citation
• Genetic and phenotypic characterisation of selected african foot-and-mouth disease virus isolates

  2015cites this paper
• PRESENTATION OF RECEPTOR-CONTACTING LOOP OF HUMAN IGE ON THE HBCAG PARTICLES

  2015cites this paper
• Design of protein nanoparticles for cell targeting and blood brain barrier crossing

  2015cites this paper
• Immunogenic virus-like particles continuously expressed in mammalian cells as a veterinary rabies vaccine candidate.

  2015cites this paper
• Induction of antibody and interferon-γ production in mice immunized with virus-like particles of swine hepatitis E virus

  2014cites this paper
• Structural Basis for the Development of Avian Virus Capsids That Display Influenza Virus Proteins and Induce Protective Immunity

  2014cites this paper
• La biotecnología en sanidad animal

  2014cites this paper
• Development and evaluation of a subunit DIVA vaccine against bluetongue virus serotype 8 in cattle

  2014cites this paper
• LA BIOTECNOLOGÍA EN SANIDAD ANIMAL ANIMAL HEALTH AND BIOTECHNOLOGY

  2014cites this paper
• Self-Assembly and Release of Peste des Petits Ruminants Virus-Like Particles in an Insect Cell-Baculovirus System and Their Immunogenicity in Mice and Goats

  2014cites this paper
• Isolation and expression of recombinant viral protein (VP2) from Iranian isolates of Infectious Pancreatic Necrosis Virus (IPNV) in Escherichia coli.

  2014cites this paper
• Virus-like particles as a vaccine against porcine reproductive and respiratory syndrome virus

  2013cites this paper
• Puesta a punto del modelo murino de infección por rotavirus y la evaluación de modelos de vacunas

  2013cites this paper
• Virus like particles as a vaccine against porcine reproductive and respiratory syndrome virus ( PRRSV )

  2013cites this paper
• Structure and Physics of Viruses

  2013cites this paper
• Construction and immunogenicity of recombinant porcine circovirus-like particles displaying somatostatin.

  2013cites this paper
• DNA Prime/Adenovirus Boost Malaria Vaccine Encoding P. falciparum CSP and AMA1 Induces Sterile Protection Associated with Cell-Mediated Immunity

  2013cites this paper
• Conformational and Thermal Stability Improvements for the Large-Scale Production of Yeast-Derived Rabbit Hemorrhagic Disease Virus-Like Particles as Multipurpose Vaccine

  2013cites this paper
• Immune responses in mice vaccinated with virus-like particles composed of the GP5 and M proteins of porcine reproductive and respiratory syndrome virus

  2013cites this paper
• Design of novel vaccines based on virus-like particles or chimeric virions.

  2013cites this paper
• Novel immunogenic baculovirus expressed virus-like particles of foot-and-mouth disease (FMD) virus protect guinea pigs against challenge.

  2013cites this paper
• B Epitope Multiplicity and B/T Epitope Orientation Influence Immunogenicity of Foot-and-Mouth Disease Peptide Vaccines

  2013cites this paper
• Virus-Like Particles: A future candidate vaccine in livestock and poultry

  2013cites this paper
• HSV-1 amplicon vectors launch the production of heterologous rotavirus-like particles and induce rotavirus-specific immune responses in mice.

  2012cites this paper
• Chimeric calicivirus-like particles elicit specific immune responses in pigs

  2012cites this paper
• Virus-like particles: potential veterinary vaccine immunogens.

  2012cites this paper
• Construction and Characterization of Virus-Like Particles: A Review

  2012cites this paper
• A Cucumber Mosaic Virus Based Expression System for the Production of Porcine Circovirus Specific Vaccines

  2012cites this paper
• Virus-like particles: The new frontier of vaccines for animal viral infections

  2012cites this paper
• From animals to humans: can vaccines make the transition?

  2012cites this paper
• Virus-like particle-based vaccines for animal viral infections

  2012cites this paper
• Infectious bronchitis virus nucleoprotein specific CTL response is generated prior to serum IgG.

  2012cites this paper
• Inclusion of a specific T cell epitope increases the protection conferred against foot-and-mouth disease virus in pigs by a linear peptide containing an immunodominant B cell site

  2012cites this paper
• Delivery strategies for novel vaccine formulations.

  2012cites this paper
• Formulation and delivery of vaccines: Ongoing challenges for animal management

  2012cites this paper
• DNA Vaccination by Electrogene Transfer

  2011cites this paper
• Safety and immunogenicity in piglets of the vaccine candidate E2-CD154, a subunit vaccine against classical swine fever. Results from phase III clinical trial

  year unknowncites this paper