Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Development

• Publication date

  1993-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 8330521
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The bride of sevenless and sevenless interaction: internalization of a transmembrane ligand.

  1992cited by this paper
• Regulation of proneural gene expression and cell fate during neuroblast segregation in the Drosophila embryo.

  1992cited by this paper
• The choice of cell fate in the epidermis of Drosophila.

  1991influential reference
• Late endosomes derive from early endosomes by maturation.

  1991cited by this paper
• Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function

  1991influential reference
• The emergence of sense organs in the wing disc of Drosophila.

  1991influential reference
• Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor

  1991cited by this paper
• Regulation of achaete-scute gene expression and sensory organ pattern formation in the Drosophila wing.

  1991influential reference
• The development of the sensory neuron pattern in the antennal disc of wild-type and mutant (lz3, ssa) Drosophila melanogaster.

  1991cited by this paper
• A role for the Drosophila neurogenic genes in mesoderm differentiation.

  1991cited by this paper
• Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc.

  1991influential reference
• The determination of sense organs in Drosophila: effect of the neurogenic mutations in the embryo.

  1991cited by this paper
• Choosing a cell fate: a view from the Notch locus.

  1991influential reference
• The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs.

  1991cited by this paper
• The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis.

  1990cited by this paper
• Cell shape changes during gastrulation in Drosophila.

  1990cited by this paper
• Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila.

  1990influential reference
• The many faces of epidermal growth factor repeats.

  1990cited by this paper
• Second-site modifiers of the split mutation of Notch define genes involved in neurogenesis in Drosophila melanogaster

  1990cited by this paper
• Pattern formation in imaginal discs.

  1990cited by this paper
• Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila.

  1990influential reference
• The many faces of epidermal growth factor repeats.

  1990cited by this paper
• Complex spatio-temporal accumulation of alternative transcripts from the neurogenic gene Delta during Drosophila embryogenesis.

  1989cited by this paper
• A tripartite interaction among alleles of Notch, Delta, and Enhancer of split during imaginal development of Drosophila melanogaster.

  1989influential reference
• The notch gene product is a glycoprotein expressed on the cell surface of both epidermal and neuronal precursor cells during Drosophila development

  1989influential reference
• The TGF-α precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction

  1989cited by this paper
• Notch is required for successive cell decisions in the developing Drosophila retina.

  1989cited by this paper
• Transmembrane TGF-α precursors activate EGF/TGF-α receptors

  1989cited by this paper
• Development of adult sensilla on the wing and notum of Drosophila melanogaster.

  1989cited by this paper
• Transmembrane TGF-alpha precursors activate EGF/TGF-alpha receptors.

  1989cited by this paper
• The emergence of order in the Drosophila pupal retina.

  1989cited by this paper
• Delta, a Drosophila neurogenic gene, is transcriptionally complex and encodes a protein related to blood coagulation factors and epidermal growth factor of vertebrates.

  1988influential reference
• Functional interactions of neurogenic genes of Drosophila melanogaster.

  1988cited by this paper
• Spatial and temporal patterns of neurogenesis in the central nervous system of Drosophila melanogaster.

  1988cited by this paper
• Cytogenetic definition and morphogenetic analysis of Delta, a gene affecting neurogenesis in Drosophila melanogaster.

  1988cited by this paper
• Neuronal differentiation in Drosophila ommatidium.

  1987cited by this paper
• Membranes of sorting organelles display lateral heterogeneity in receptor distribution

  1987cited by this paper
• glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans.

  1987cited by this paper
• Mutations altering the structure of epidermal growth factor-like coding sequences at the Drosophila Notch locus.

  1987cited by this paper
• The neurogenic gene Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF‐like repeats

  1987influential reference
• Lineage analysis of transplanted individual cells in embryos of Drosophila melanogaster

  1986cited by this paper
• Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors

  1986cited by this paper
• Early events in insect neurogenesis. II. The role of cell interactions and cell lineage in the determination of neuronal precursor cells.

  1985cited by this paper
• Early events in insect neurogenesis. I. Development and segmental differences in the pattern of neuronal precursor cells.

  1985cited by this paper
• Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats.

  1985cited by this paper
• Genetic interactions in early neurogenesis of Drosophila melanogaster.

  1985cited by this paper
• The molecular genetics of the Notch locus in Drosophila melanogaster.

  1985influential reference
• Neuronal development in the Drosophila retina: monoclonal antibodies as molecular probes.

  1984cited by this paper
• Intracellular site of asialoglycoprotein receptor-ligand uncoupling: double-label immunoelectron microscopy during receptor-mediated endocytosis.

  1983cited by this paper
• On the phenotype and development of mutants of early neurogenesis inDrosophila melanogaster

  1983cited by this paper
• Construction of plasmids for expression of Rous sarcoma virus transforming protein, p60src, in Escherichia coli.

  1982cited by this paper
• Temperature-sensitive periods and autonomy of pleiotropic effects of l(1)Nts1, a conditional notch lethal in Drosophila.

  1978cited by this paper
• The Genetics and Biology of Drosophila

  1976cited by this paper
• Allelic negative complementation at the Abruptex locus of Drosophila melanogaster.

  1975cited by this paper
• Genetic variations of Drosophila melanogaster

  1967cited by this paper

• Delta-dependent Notch activation closes the early neuroblast temporal program to promote lineage progression and neurogenesis termination in Drosophila

  2024cites this paper
• Delta-dependent Notch activation closes the early neuroblast temporal program to promote lineage progression and neurogenesis termination in Drosophila

  2023cites this paper
• Cancer immunotherapies: advances and bottlenecks

  2023cites this paper
• TM2D3, a mammalian homologue of Drosophila neurogenic gene product Almondex, regulates surface presentation of Notch receptors

  2023cites this paper
• Notch signaling sculpts the stem cell niche

  2022cites this paper
• The developmental origins of Notch-driven intrahepatic bile duct disorders

  2021cites this paper
• Single-cell Senseless protein analysis reveals metastable states during the transition to a sensory organ fate

  2021cites this paper
• Ghost in the Machine: The Peripodial Epithelium

  2020cites this paper
• The Abelson tyrosine kinase and the Nedd4-family ubiquitin ligase Suppressor of Deltex converge at the Notch PPxY motif to regulate endosomal trafficking and signaling

  2020cites this paper
• Wg secreted by conventional Golgi transport diffuses and forms Wg gradient whereas Wg tethered to extracellular vesicles do not diffuse

  2020cites this paper
• Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila Eye

  2020cites this paper
• Direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila

  2019cites this paper
• An agent-based model of the Notch signaling pathway elucidates three levels of complexity in the determination of developmental patterning

  2019cites this paper
• The Exocyst Component Sec3 Controls Egg Chamber Development Through Notch During Drosophila Oogenesis

  2019cites this paper
• aaquetzalli is required for epithelial cell polarity and neural tissue formation in Drosophila

  2018cites this paper
• Integration of Drosophila and Human Genetics to Understand Notch Signaling Related Diseases.

  2018cites this paper
• A new paramutation-like example at the Delta gene of Drosophila

  2017cites this paper
• A genetic toolkit for tagging intronic MiMIC containing genes

  2015cites this paper
• Programmed Cell Death and Caspase Functions During Neural Development.

  2015cites this paper
• Notch signaling induces cell proliferation in the labrum in a regulatory network different from the thoracic legs.

  2015cites this paper
• Identification and analysis of novel insect head patterning genes

  2015cites this paper
• Programmed cell death in neurodevelopment.

  2015cites this paper
• Cell death in development: Signaling pathways and core mechanisms.

  2015cites this paper
• Notch Controls Cell Adhesion in the Drosophila Eye

  2014cites this paper
• Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates

  2014cites this paper
• The Role of Notch Signaling in T Cell-mediated Immune Disorders.

  2013cites this paper
• Notch signaling from the endosome requires a conserved dileucine motif

  2013cites this paper
• Lateral inhibition and neurogenesis: novel aspects in motion.

  2013cites this paper
• Cell Morphogenesis: Tracing the Paths of Induction During Drosophila Ommatidial Development

  2013cites this paper
• Identification of genes regulated by the Drosophila transcription factor Hindsight

  2013cites this paper
• Regulation of neuronal differentiation at the neurogenic wavefront

  2012cites this paper
• Hox proteins coordinate peripodial decapentaplegic expression to direct adult head morphogenesis in Drosophila.

  2012cites this paper
• The Notch signalling system: recent insights into the complexity of a conserved pathway

  2012cites this paper
• Endocytosis in Notch Signaling Activation

  2012cites this paper
• A study of epithelial cell delamination in Drosophila

  2011cites this paper
• My what big eyes you have: How the Drosophila retina grows

  2011cites this paper
• Cellular interactions during gastrulation in the amphipod crustacean, Parhyale hawaiensis

  2011cites this paper
• A Novel Interaction Between hedgehog and Notch Promotes Proliferation at the Anterior–Posterior Organizer of the Drosophila Wing

  2011cites this paper
• Notch signaling regulates neuroepithelial stem cell maintenance and neuroblast formation in Drosophila optic lobe development.

  2011cites this paper
• Notch/Delta signalling is not required for segment generation in the basally branching insect Gryllus bimaculatus

  2011cites this paper
• Endocytosis and intracellular trafficking of Notch and its ligands.

  2010cites this paper
• Dynamic filopodia transmit intermittent Delta-Notch signaling to drive pattern refinement during lateral inhibition.

  2010cites this paper
• Developmental Characterization of Cara Mitad: A Drosophila Nuclear Receptor Co-Regulator

  2010cites this paper
• Notch ligand activity is modulated by glycosphingolipid membrane composition in Drosophila melanogaster

  2010cites this paper
• Control of Notch-ligand endocytosis by ligand-receptor interaction

  2010cites this paper
• New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes.

  2010cites this paper
• Notch and delta mRNAs in early‐stage and mid‐stage drosophila embryos exhibit complementary patterns of protein‐producing potentials

  2010cites this paper
• Canonical and non-canonical Notch ligands.

  2010cites this paper
• A novel interaction between hedgehog and Notch promotes proliferation at the AP organizer of the Drosophila wing imaginal disc

  2010cites this paper
• Identification de nouveaux régulateurs du trafic et de l'activité signalisatrice des ligands du récepteur Notch chez la drosophile : analyse du rôle des glycosphingolipides

  2009cites this paper
• Proteolytic Activation of Notch Signaling

  2009cites this paper
• Notch signaling: the core pathway and its posttranslational regulation.

  2009cites this paper
• On the roles of Notch, Delta, kuzbanian, and inscuteable during the development of Drosophila embryonic neuroblast lineages.

  2009cites this paper
• Notch and suppressor of Hairless regulate levels but not patterns of Delta expression in Drosophila

  2008cites this paper
• Delta-Notch Signaling: Functional and Mechanistic Studies of Receptor and Ligand Proteolysis and Endocytosis

  2008cites this paper
• The clathrin-binding motif and the J-domain of Drosophila Auxilin are essential for facilitating Notch ligand endocytosis

  2008cites this paper
• Polarized exocytosis and transcytosis of Notch during its apical localization in Drosophila epithelial cells

  2007cites this paper
• Delta expression in post‐mitotic neurons identifies distinct subsets of adult‐specific lineages in Drosophila

  2007influential citation
• Notch Signaling – Constantly on the Move

  2007cites this paper
• Wing vein patterning in Drosophila and the analysis of intercellular signaling.

  2007cites this paper
• Delta and Egfr expression are regulated by Importin-7/Moleskin in Drosophila wing development.

  2007cites this paper
• De novo predictions of localization of gene expression confirmed by published experiments

  2007cites this paper
• γ-Secretase Mediated Proteolysis: At the Cutting Edge of Notch Signaling

  2007cites this paper
• Structure–Function Analysis of Delta Trafficking, Receptor Binding and Signaling in Drosophila

  2006cites this paper
• Why is delta endocytosis required for effective activation of notch?

  2006influential citation
• Endocytosis-independent mechanisms of Delta ligand proteolysis.

  2006cites this paper
• Autoreactive B cell development in the periphery

  2006cites this paper
• Endocytosis, endosome trafficking, and the regulation of Drosophila development.

  2006cites this paper
• Evidence for the involvement of dominant‐negative Notch molecules in the normal course of Drosophila development

  2006cites this paper
• Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila.

  2006cites this paper
• The Cdi/TESK1 kinase is required for Sevenless signaling and epithelial organization in the Drosophila eye

  2006cites this paper
• Interactions between the Notch, EGFR, and decapentaplegic signaling pathways regulate vein differentiation during Drosophila pupal wing development

  2005cites this paper
• Conserved cross‐interactions in Drosophila and Xenopus between Ras/MAPK signaling and the dual‐specificity phosphatase MKP3

  2005cites this paper
• Bunched sets a boundary for Notch signaling to pattern anterior eggshell structures during Drosophila oogenesis.

  2005cites this paper
• A major bristle QTL from a selected population of Drosophila uncovers the zinc-finger transcription factor poils-au-dos, a repressor of achaete-scute.

  2005cites this paper
• Evidence that nervy, the Drosophila homolog of ETO/MTG8, promotes mechanosensory organ development by enhancing Notch signaling.

  2005cites this paper
• Regulation of post-embryonic neuroblasts by Drosophila Grainyhead.

  2005cites this paper
• The Notch targets Esr1 and Esr10 are differentially regulated in Xenopus neural precursors

  2005cites this paper
• The roles of receptor and ligand endocytosis in regulating Notch signaling

  2005cites this paper
• IrreC/rst-mediated cell sorting during Drosophila pupal eye development depends on proper localisation of DE-cadherin

  2005cites this paper
• Three modules of zebrafish Mind bomb work cooperatively to promote Delta ubiquitination and endocytosis.

  2004cites this paper
• Erratum: Folding proteins in fatal ways

  2004cites this paper
• Regulation of Notch signaling by Drosophila heparan sulfate 3-O sulfotransferase

  2004influential citation
• Notch signaling patterns Drosophila mesodermal segments by regulating the bHLH transcription factor twist

  2004cites this paper
• Regulation of notch signaling activity.

  2004cites this paper
• Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch

  2004cites this paper
• The roles of cis-inactivation by Notch ligands and of neuralized during eye and bristle patterning in Drosophila

  2004cites this paper
• The role of DE-cadherin during cellularization, germ layer formation and early neurogenesis in the Drosophila embryo.

  2004cites this paper
• Unidirectional Notch signaling depends on continuous cleavage of Delta

  2004cites this paper
• Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo

  2003cites this paper
• Cell Death in Drosophila

  2003cites this paper
• Notch steers Drosophila ISNb motor axons by regulating the Abl signaling pathway.

  2003cites this paper
• Bowl is required downstream of Notch for elaboration of distal limb patterning

  2003cites this paper
• Neural Stem and Progenitor Cells: Lineage and Cell Fate Determination

  2003cites this paper
• Pattern formation in the Drosophila wing: The development of the veins.

  2003cites this paper
• Activation of the knirps locus links patterning to morphogenesis of the second wing vein in Drosophila

  2003cites this paper
• Snail is required for Delta endocytosis and Notch-dependent activation of single-minded expression

  2003influential citation
• Echinoid facilitates Notch pathway signalling during Drosophila neurogenesis through functional interaction with Delta

  2003cites this paper
• Regulation of Notch Signaling by a Novel Mechanism Involving Suppressor of Hairless Stability and Carboxyl Terminus-Truncated Notch

  2003cites this paper
• Patterning the fly eye: the role of apoptosis.

  2003cites this paper