The T cell receptor: the alpha and beta chains define idiotype, and antigen and MHC specificity.

No abstract is available for this paper.

• Publication year

  1985

• Venue

  Cell

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 2410143
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Partial primary structure of the alpha and beta chains of human tumor T-cell receptors.

  1985cited by this paper
• Purification and NH2-terminal amino acid sequencing of the beta subunit of a human T-cell antigen receptor.

  1984cited by this paper
• Mouse T cell antigen receptor: structure and organization of constant and joining gene segments encoding the beta polypeptide.

  1984cited by this paper
• A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

  1984cited by this paper
• Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

  1984cited by this paper
• A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

  1984cited by this paper
• Isolation of cDNA clones encoding the 20K T3 glycoprotein of human T-cell receptor complex

  1984cited by this paper
• Immunoglobulin-like nature of the alpha-chain of a human T-cell antigen/MHC receptor.

  1984cited by this paper
• The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype

  1984cited by this paper
• A third type of murine T-cell receptor gene

  1984cited by this paper
• Primary structure of human T-cell receptor alpha-chain.

  1984cited by this paper
• Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen.

  1984cited by this paper
• Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

  1984cited by this paper
• Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line

  1984cited by this paper
• The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides.

  1983cited by this paper
• The mouse T cell receptor: structural heterogeneity of molecules of normal T cells defined by xenoantiserum.

  1983cited by this paper
• Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex

  1983cited by this paper
• The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas.

  1983cited by this paper
• Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor

  1983cited by this paper
• Major histocompatibility complex-controlled, antigen-presenting cell- expressed specificity of T cell antigen recognition. Identification of a site of interaction and its relationship to Ir genes

  1983cited by this paper
• The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I- specificity

  1983cited by this paper
• Peptide variability exists within alpha and beta subunits of the T cell receptor for antigen

  1983cited by this paper
• The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody

  1983cited by this paper
• Antigen recognition by cloned cytotoxic T lymphocytes follows rules predicted by the altered-self hypothesis

  1982cited by this paper
• Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody.

  1982cited by this paper
• Antigen-specific. I region-restricted interactions in vitro between tumor cell lines and T cell hybridomas.

  1982cited by this paper
• Contribution of antigen-presenting cell major histocompatibility complex gene products to the specificity of antigen-induced T cell activation

  1982cited by this paper
• Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

  1981cited by this paper
• Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

  1979cited by this paper

• Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.

  2024cites this paper
• Clinical significance of T cell receptor repertoire in primary Sjogren's syndrome

  2022cites this paper
• Becoming aware of γδ T cells.

  2022cites this paper
• TMEM16F mediates bystander TCR-CD3 membrane dissociation at the immunological synapse and potentiates T cell activation

  2021cites this paper
• Sudan ebolavirus long recovered survivors produce GP-specific Abs that are of the IgG1 subclass and preferentially bind FcγRI

  2017cites this paper
• Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4+ T-cell repertoire selection

  2012cites this paper
• Physical and Functional Bivalency Observed Among TCR/CD3 Complexes Isolated from Primary T Cells

  2011cites this paper
• This information is current as Primary T Cells Among TCR / CD 3 Complexes Isolated from Physical and Functional Bivalency Observed

  2011cites this paper
• Muscle CARs and TcRs: turbo-charged technologies for the (T cell) masses

  2011cites this paper
• Germline-encoded amino acids in the αβ T cell receptor control thymic selection

  2009cites this paper
• Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells

  2007cites this paper
• Expression and interaction studies of recombinant human monoclonal antibodies

  2007cites this paper
• Characterization of the immunophenotype and the metastatic properties of a murine T-lymphoma cell line. Unexpected expression of cytoplasmatic CD4

  2007cites this paper
• CD4 T Cell-Induced, Bid-Dependent Apoptosis of Cutaneous Dendritic Cells Regulates T Cell Expansion and Immune Responses1

  2006cites this paper
• Etude des populations lymphocytaires exprimant des récepteurs spécifiques de molécules HLA de classe I au cours de l'hépatite virale C chronique

  2006cites this paper
• New understanding of immunological mechanisms.

  2006cites this paper
• Susceptibility genetics of systemic lupus erythematosus

  2005cites this paper
• Analysis of the Major Histocompatibility Complex in Graft Rejection Revisited by Gene Expression Profiles

  2004cites this paper
• Restriction fragment length polymorphism of the human T cell receptor alpha gene

  2004cites this paper
• T‐cell hybridoma specific for myelin oligodendrocyte glycoprotein‐35–55 peptide produced from HLA‐DRB1*1501‐transgenic mice

  2004cites this paper
• CIITA-regulated plexin-A1 affects T-cell–dendritic cell interactions

  2003cites this paper
• Natural autoantibodies to TCR public idiotopes: potential roles in immunomodulation.

  2003cites this paper
• Genetic Restriction Elements Used To Recognize the KLH by Various T Cell Clones and Hybridomas

  2003cites this paper
• Critical Relationship Between TCR Signaling Potential and TCR Affinity During Thymocyte Selection

  2000cites this paper
• Costimulatory action of glycoinositolphospholipids from Trypanosoma cruzi: increased interleukin 2 secretion and induction of nuclear translocation of the nuclear factor of activated T cells 1

  1999cites this paper
• Display of functional alphabeta single-chain T-cell receptor molecules on the surface of bacteriophage.

  1998cites this paper
• Mechanisms influencing the selection of T cell epitopes by MHC class II molecules.

  1997cites this paper
• T cell receptor usage by HLA-DR3-specific T cell clones isolated from a renal allograft.

  1997cites this paper
• Delivery of antigens to the MHC class I pathway using bacterial toxins.

  1997cites this paper
• Experimental autoimmune myasthenia gravis in B10.BV8S2 transgenic mice: preferential usage of TCRAV1 gene by lymphocytes responding to acetylcholine receptor.

  1997cites this paper
• Collagen-induced arthritis, an animal model of autoimmunity.

  1997cites this paper
• MCA Sarcomas Induced in scid Mice are More Immunogenic than MCA Sarcomas Induced in Congenic, Immunocompetent Mice

  1997cites this paper
• Influence of the NH2-terminal Amino Acid of the T Cell Receptor α Chain on Major Histocompatibility Complex (MHC) Class II + Peptide Recognition

  1997cites this paper
• Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage

  1996cites this paper
• Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes.

  1996cites this paper
• alpha/beta-T cell receptor-directed therapy in rat allograft recipients. Long-term survival of cardiac allografts after pretreatment with R73 mAb is associated with upregulation of Th2-type cytokines.

  1996cites this paper
• Plasticity of the T cell receptor repertoire in TCR beta-chain transgenic mice.

  1996cites this paper
• Forces Molding Circulating T‐Cell Repertoires

  1995cites this paper
• alpha/beta-T cell receptor-directed therapy in rat cardiac allograft recipients. Treatment prior to alloantigen exposure prevents sensitization and abrogates accelerated rejection.

  1995cites this paper
• Identification of the epitope recognized by the human V beta 5-specific monoclonal antibody 42/1C1. Potential implications for disease therapy.

  1995cites this paper
• Analysis of T-cell receptor V beta expression among V alpha subsets. Evidence for tight regulation of the combinatorial diversity.

  1995cites this paper
• A peptide binding weakly to the major histocompatibility molecule augments T cell responses

  1994cites this paper
• Characterization of the T cell determinants in the induction of autoimmune arthritis by bovine alpha 1(II)-CB11 in H-2q mice.

  1994cites this paper
• Binding of a soluble alpha beta T-cell receptor to superantigen/major histocompatibility complex ligands.

  1994cites this paper
• HLA and T-cell receptor polymorphisms in Belgian multiple sclerosis patients: no evidence for disease association with the T-cell receptor.

  1994cites this paper
• CD3: Structure, function, and role of immunostaining in clinical practice

  1994cites this paper
• TCR gamma delta cells: mysterious cells of the immune system.

  1994cites this paper
• Conserved amino acid residues in the complementarity-determining region 1 of the TCR beta-chain are involved in the recognition of conventional Ag and Mls-1 superantigen.

  1994cites this paper
• T cell receptor beta chain dimers on immature thymocytes from normal mice.

  1993cites this paper
• Antigen presenting cell-derived co-stimulatory signals can selectively regulate IL-2 and IL-4 production from a Th0 cell hybridoma.

  1993cites this paper
• A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein.

  1993cites this paper
• Restricted T cell receptor expression by human T cell clones specific for mycobacterial 65‐kDa heat‐shock protein: Selective in vivo expansion of T cells bearing defined receptors

  1993cites this paper
• Recognition of antigen and superantigen by cytotoxic lymphocytes

  1993cites this paper
• The biochemistry and cell biology of antigen processing and presentation.

  1993cites this paper
• Characterization of T cells expressing the gamma/delta antigen receptor in human renal allografts.

  1993cites this paper
• Tolerance induction to an alloepitope involves antibodies interacting with the T cells activated by the alloepitope.

  1992cites this paper
• Co-expression of T-cell receptor beta and delta mRNA detected at high frequency in hybridomas derived from adult thymus.

  1992cites this paper
• Clonal heterogeneity of superantigen reactivity in human V beta 6+ T cell clones. Limited contributions of V beta sequence polymorphisms.

  1992cites this paper
• Specific low-affinity recognition of major histocompatibility complex plus peptide by soluble T-cell receptor

  1992cites this paper
• Variable gene usage of T cell receptor gamma- and delta-chain transcripts expressed in synovia and peripheral blood of patients with rheumatoid arthritis.

  1992cites this paper
• Expansion of murine T cells bearing a unique T cell receptor beta-chain in Friend virus-induced tumor in situ.

  1992cites this paper
• Molecular immunology and immunopharmacology of allograft rejection.

  1992cites this paper
• Evidence for oligoclonality of T cell receptor delta chain transcripts expressed in rheumatoid arthritis patients.

  1992cites this paper
• T cell receptor (TCR) beta chain homodimers on the surface of immature but not mature alpha, gamma, delta chain deficient T cell lines.

  1992cites this paper
• T cells expressing variable elements of T-cell receptor beta 8 and beta 2 chain regulate murine IgE production.

  1992cites this paper
• Expression and combinatorial diversity of germ line-encoded T cell receptor V genes in human peripheral blood T cells.

  1992cites this paper
• T-cell selection and T-cell receptor variable beta-chain usage in chronic hemodialysis patients.

  1992cites this paper
• Increased frequency of 2,4,6‐trinitrophenyl (TNP)‐specific, H‐2b‐restricted cytotoxic T lymphocyte precursors in transgenic mice expressing a T cell receptor β chain gene from an H‐2b‐restricted, TNP‐specific cytolytic T cell clone

  1992cites this paper
• CD3- T cells with cis- or trans-acting mutations affecting expression of T cell receptor beta-chain mRNA.

  1992cites this paper
• T Cells and Human Autoimmune Thyroid Disease: Emerging Data Show Lack of Need to Invoke Suppressor T Cell Problems

  1992cites this paper
• T hybridoma alpha/beta gene transfected in a murine T cell hybridoma: role of CD4 molecule in vitro and in vivo--engraftment in SCID mice induces T cell maturation.

  1992cites this paper
• Pertussis toxin prevents the induction of peripheral T cell anergy and enhances the T cell response to an encephalitogenic peptide of myelin basic protein.

  1991cites this paper
• Allorecognition in T-cell receptor (beta-chain) transgenic mice.

  1991cites this paper
• Enhanced serum levels of soluble HLA class I molecules are induced by treatment with recombinant interferon‐gamma (IFN‐γ)

  1991cites this paper
• Murine T cell-stimulatory peptides from the 19-kDa antigen of Mycobacterium tuberculosis. Epitope-restricted homology with the 28-kDa protein of Mycobacterium leprae.

  1991cites this paper
• Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor V beta

  1991cites this paper
• Interfaces of the yeast killer phenomenon.

  1991cites this paper
• Biology of murine gamma delta T cells.

  1991cites this paper
• Characterization of autoreactive T cells. Relative importance of self-peptides versus MHC.

  1991cites this paper
• Physical mapping of the CD3 gene cluster.

  1990cites this paper
• Respective contribution of intracellular calcium release and extracellular calcium influx for interleukin-2 synthesis in activated T-cell hybrids.

  1990cites this paper
• Structure-function relationships among highly diverse T cells that recognize a determinant from influenza virus hemagglutinin

  1990cites this paper
• Increased numbers of T lymphocytes with gamma delta-positive antigen receptors in a subgroup of individuals with pulmonary sarcoidosis.

  1990cites this paper
• Flexibility of the T cell repertoire. Self tolerance causes a shift of T cell receptor gene usage in response to insulin

  1990cites this paper
• Expression of identical V alpha V beta gene pairs by IE-alloreactive and IE-restricted, antigen-specific T cells from MHC disparate mice. Evidence for thymic selection of V(D)J combinations.

  1990cites this paper
• Stimulation of B10.BR T cells with superantigenic staphylococcal toxins.

  1990cites this paper
• Defects in signal transduction caused by a T cell receptor beta chain substitution.

  1990cites this paper
• Preferential usage of V alpha 4 and V beta 10 T cell receptor genes by lymphocytic choriomeningitis virus glycoprotein-specific H-2Db-restricted cytotoxic T cells.

  1990cites this paper
• T-Cell receptor and autoimmune disease

  1990cites this paper
• MHC class II-derived peptides can bind to class II molecules, including self molecules, and prevent antigen presentation

  1990cites this paper
• Isolation of novel complementary DNA clones from T lymphoma cells: one encodes a putative multiple membrane-spanning protein.

  1990cites this paper
• The use of human T-lymphocyte clones to study T-cell function in allergic contact dermatitis to urushiol.

  1990cites this paper
• Identification of the region of T cell receptor beta chain that interacts with the self-superantigen MIs-1a.

  1990cites this paper
• Lymphocyte surface antigen L25 is a member of the integrin receptor superfamily.

  1989cites this paper
• Diversity of the immunoglobulin gene superfamily.

  1989cites this paper
• Molecular Interactions, T‐Cell Subsets and a Role of the CD4/CD8:p56lck Complex in Human T‐Cell Activation

  1989cites this paper
• Diminished expression of the T cell receptor on the expanded lymphocyte population in MRL/Mp-lpr/lpr mice.

  1989cites this paper
• Costimulatory signal provided by a B-lymphoblastoid cell line and its Ia-negative variant.

  1989cites this paper
• Differential Growth Requirements and Effector Functions of α/β and γ/δ Human T Cells

  1989cites this paper
• Thymocyte development: an analysis of T cell receptor gene expression in 519 newborn thymocyte hybridomas

  1989cites this paper