Early age at time of primary Epstein-Barr virus infection results in poorly controlled viral infection in infants from Western Kenya: clues to the etiology of endemic Burkitt lymphoma.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Infectious Diseases

• Publication date

  2012-03-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/infdis/jir872PMID 22301635PMCID PMC3282570
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Elevated anti-Zta IgG levels and EBV viral load are associated with site of tumor presentation in endemic Burkitt's lymphoma patients: a case control study

  2010cited by this paper
• Serological evidence for long‐term epstein–barr virus reactivation in children living in a holoendemic malaria region of Kenya

  2009cited by this paper
• Infection of neonates with murine gammaherpesvirus 68 results in enhanced viral persistence in lungs and absence of infectious mononucleosis syndrome.

  2008cited by this paper
• Microscopy underestimates the frequency of Plasmodium falciparum infection in symptomatic individuals in a low transmission highland area.

  2008cited by this paper
• A Molecular Link between Malaria and Epstein–Barr Virus Reactivation

  2007cited by this paper
• Exposure to holoendemic malaria results in suppression of Epstein-Barr virus-specific T cell immunosurveillance in Kenyan children.

  2007cited by this paper
• Burkitt lymphoma: revisiting the pathogenesis of a virus-associated malignancy.

  2007cited by this paper
• Spatial distribution of Burkitt’s lymphoma in Kenya and association with malaria risk

  2007cited by this paper
• Spatial clustering of endemic Burkitt's lymphoma in high‐risk regions of Kenya

  2007cited by this paper
• Single-Assay Combination of Epstein-Barr Virus (EBV) EBNA1- and Viral Capsid Antigen-p18-Derived Synthetic Peptides for Measuring Anti-EBV Immunoglobulin G (IgG) and IgA Antibody Levels in Sera from Nasopharyngeal Carcinoma Patients: Options for Field Screening

  2006cited by this paper
• Circulating Epstein–Barr Virus in Children Living in Malaria‐Endemic Areas

  2005cited by this paper
• Exposure to holoendemic malaria results in elevated Epstein-Barr virus loads in children.

  2005influential reference
• Acute Infection with Epstein-Barr Virus Targets and Overwhelms the Peripheral Memory B-Cell Compartment with Resting, Latently Infected Cells

  2004influential reference
• Persistent and Selective Deficiency of CD4+ T Cell Immunity to Cytomegalovirus in Immunocompetent Young Children1

  2004cited by this paper
• Toward Standardization of Epstein-Barr Virus DNA Load Monitoring: Unfractionated Whole Blood as Preferred Clinical Specimen

  2001cited by this paper
• Epstein-Barr virus (EBV) infection in infancy.

  2001influential reference
• Detection of Plasmodium falciparum malaria parasites in vivo by real-time quantitative PCR.

  2001cited by this paper
• Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection

  2000cited by this paper
• Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa.

  1997cited by this paper
• Relationships between Plasmodium falciparum transmission by vector populations and the incidence of severe disease at nine sites on the Kenyan coast.

  1995cited by this paper
• Localization and diagnostic application of immunodominant domains of the BFRF3-encoded Epstein-Barr virus capsid protein.

  1994cited by this paper
• Primary infections of Epstein-Barr virus, cytomegalovirus, and human herpesvirus-6.

  1993cited by this paper
• Malaria, Epstein-Barr virus, and the genesis of lymphomas.

  1989cited by this paper
• Epitope-mapping on the Epstein-Barr virus major capsid protein using systematic synthesis of overlapping oligopeptides.

  1988cited by this paper
• Interferons

  1986cited by this paper
• Epidemiological evidence for the role of falciparum malaria in the pathogenesis of Burkitt's lymphoma.

  1985cited by this paper
• Epstein-Barr virus and Burkitt's lymphoma worldwide: the causal relationship revisited.

  1985cited by this paper
• Primary epstein‐barr virus infections in african infants. I. Decline of maternal antibodies and time of infection

  1978influential reference
• Primary epstein‐barr virus infections in African infants. II. Clinical and serological observations during seroconversion

  1978cited by this paper
• Epidemiological evidence for causal relationship between Epstein-Barr virus and Burkitt's lymphoma from Ugandan prospective study

  1978influential reference
• Is Burkitt's lymphoma related to perinatal infection by Epstein-Barr virus?

  1977cited by this paper

• EBV Type 1 versus Type 2: A determinant of NK cell anti-tumor activity in Burkitt lymphoma

  2026cites this paper
• CD4 and CD8 T-cell response is dominated by IL-10–secreting cells in children with uncomplicated Plasmodium falciparum malaria

  2025cites this paper
• Burkitt Lymphoma.

  2025cites this paper
• Infectious Mononucleosis.

  2025cites this paper
• Epstein-Barr virus (EBV) serology and its impact on oral human papillomavirus (HPV) infection outcomes in children during early childhood

  2025cites this paper
• Epstein-Barr virus type 2 infection is associated with higher viral loads in pediatric tonsils from western Kenya

  2025cites this paper
• A single-center retrospective analysis of serological and molecular findings in patients infected with Epstein-Barr virus

  2025cites this paper
• Acute Epstein Barr Virus is a risk factor for severe malaria in infants under 24 months

  2025cites this paper
• Sustained activation induced cytidine deaminase (AID) expression in B cells following Plasmodium falciparum malaria infection in Kenyan children.

  2025cites this paper
• Understanding EBV infection and EBV-associated lymphomas in children.

  2025cites this paper
• Immune cell phenotype and function patterns across the life course in individuals from rural Uganda

  2024cites this paper
• Increased human herpesvirus-8 neutralizing response during remission from Kaposi's sarcoma.

  2024cites this paper
• Coinfection of EBV with other pathogens: a narrative review

  2024cites this paper
• Natural killer cell antibody‐dependent cellular cytotoxicity to Plasmodium falciparum is impacted by cellular phenotypes, erythrocyte polymorphisms, parasite diversity and intensity of transmission

  2024cites this paper
• The unappreciated role of developing B cells in chronic gammaherpesvirus infections

  2024cites this paper
• HIV-associated cancers and lymphoproliferative disorders caused by Kaposi sarcoma herpesvirus and Epstein-Barr virus

  2024cites this paper
• Altered EBV specific immune control in multiple sclerosis.

  2024cites this paper
• Chronic Epstein-Barr viral load carriage after pediatric organ transplantation

  2024cites this paper
• Comparison of Epstein-Barr virus and Kaposi’s sarcoma-associated herpesvirus viral load in peripheral blood mononuclear cells and oral fluids of HIV-negative individuals aged 3 to 89 years from Uganda

  2023cites this paper
• Modulation of Epstein-Barr-Virus (EBV)-Associated Cancers by Co-Infections

  2023cites this paper
• Sickle cell allele HBB‐rs334(T) is associated with decreased risk of childhood Burkitt lymphoma in East Africa

  2023cites this paper
• Correlation between severe malaria and EBV endemicity in children under five years in Ghana

  2023influential citation
• Hemoglobinopathies, merozoite surface protein-2 gene polymorphisms, and acquisition of Epstein Barr virus among infants in Western Kenya

  2023influential citation
• Epstein–Barr virus (EBV) antibody changes over time in a general population cohort in rural Uganda, 1992–2008

  2023cites this paper
• Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma

  2023influential citation
• Hemin treatment drives viral reactivation and plasma cell differentiation of EBV latently infected B cells

  2023cites this paper
• Plasmodium falciparum malaria is associated with increased KSHV seropositivity and higher KSHV antibody breadth and magnitude: results of a case-control study from rural Uganda.

  2023cites this paper
• Effect of Malaria Infection on Epstein-Barr Virus Persistence in Kenyan Children.

  2023cites this paper
• The IPTA Nashville Consensus Conference on Post‐Transplant lymphoproliferative disorders after solid organ transplantation in children: III – Consensus guidelines for Epstein‐Barr virus load and other biomarker monitoring

  2023cites this paper
• Comparison of Epstein–Barr virus and Kaposi’s sarcoma-associated herpesvirus viral load in peripheral blood mononuclear cells and oral fluids of HIV-negative individuals aged 3–89 years from Uganda

  2023cites this paper
• Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria

  2023cites this paper
• Profiling genome-wide recombination in Epstein Barr virus reveals type-specific patterns and associations with endemic-Burkitt lymphoma

  2022cites this paper
• Impact of Epstein-Barr virus co-infection on natural acquired Plasmodium vivax antibody response

  2022cites this paper
• Epstein-Barr Virus in Burkitt Lymphoma in Africa Reveals a Limited Set of Whole Genome and LMP-1 Sequence Patterns: Analysis of Archival Datasets and Field Samples From Uganda, Tanzania, and Kenya

  2022cites this paper
• Maternal HIV Infection as a Risk Factor for Primary Epstein-Barr Virus Infection in Kenyan Infants

  2022cites this paper
• Epstein-Barr Virus and Malaria Interactions: Immunology Perspective

  2022cites this paper
• Hepatic Epstein-Barr Virus-Associated Smooth Muscle Tumor in a Heart and Liver Transplant Recipient

  2022cites this paper
• Spatial Distribution of Incident Pediatric Burkitt Lymphoma in Central and Northern Malawi and Association With Malaria Prevalence

  2022cites this paper
• Poorly cytotoxic terminally differentiated CD56(neg)CD16(pos) Poorly cytotoxic terminally differentiated CD56(neg)CD16(pos) NK cells accumulate in Kenyan children with Burkitt lymphomas NK cells accumulate in Kenyan children with Burkitt lymphomas

  2022cites this paper
• Malaria Is Associated With Kaposi Sarcoma-Associated Herpesvirus Seroconversion in a Cohort of Western Kenyan Children

  2021influential citation
• Epstein-Barr virus infection and its lifelong autoimmune ramifications in developed and developing nations

  2021cites this paper
• Primary Peripheral Epstein-Barr Virus Infection Can Lead to CNS Infection and Neuroinflammation in a Rabbit Model: Implications for Multiple Sclerosis Pathogenesis

  2021cites this paper
• Epstein-Barr Virus

  2021cites this paper
• Epidemiological risk factors associated with primary infection by Epstein–Barr virus in HIV-1-positive subjects in the Brazilian Amazon region

  2021cites this paper
• [Infectious mononucleosis in practice of otorhinolaryngologist].

  2021cites this paper
• HIV-exposed infants with EBV infection have a reduced persistence of the immune response to the HBV vaccine

  2021cites this paper
• Risk factors for post‐transplant Epstein‐Barr virus events in pediatric recipients of hematopoietic stem cell transplants

  2021cites this paper
• The burden of Epstein-Barr virus infections in children.

  2021cites this paper
• Association of killer cell immunoglobulin-like receptors with endemic Burkitt lymphoma in Kenyan children

  2021cites this paper
• The burden of Epstein-Barr virus infections in children

  2021cites this paper
• Defective monocyte enzymatic function and an inhibitory immune phenotype in HIV-exposed uninfected African infants in the era of highly active anti-retroviral therapy

  2021cites this paper
• Quantitative cytokine level of TNF-α, IFN-γ, IL-10, TGF-β and circulating Epstein-Barr virus DNA load in individuals with acute Malaria due to P. falciparum or P. vivax or double infection in a Malaria endemic region in Indonesia

  2021cites this paper
• Epstein–Barr Virus Prevalence at Diagnosis and Seroconversion during Follow-Up in Pediatric Inflammatory Bowel Disease

  2021cites this paper
• Technical Aspects of Epstein-Barr Viral Load Assays

  2021cites this paper
• Interplay between IL-10, IFN-γ, IL-17A and PD-1 Expressing EBNA1-Specific CD4+ and CD8+ T Cell Responses in the Etiologic Pathway to Endemic Burkitt Lymphoma

  2021cites this paper
• Neutralizing Antibodies Protect against Oral Transmission of Lymphocryptovirus

  2020cites this paper
• Risk factors for Burkitt lymphoma in East African children and minors: A case–control study in malaria‐endemic regions in Uganda, Tanzania and Kenya

  2020cites this paper
• Distinctive EBV infection characteristics in children from a developing country.

  2020cites this paper
• Natural Killer cell transcriptome during primary EBV infection and EBV associated Hodgkin Lymphoma in children-A preliminary observation.

  2020cites this paper
• Clinical and biological factors associated with early Epstein-Barr Virus infection in HIV-Exposed Uninfected Infants in Eastern Uganda.

  2020cites this paper
• Kaposi Sarcoma-associated herpesvirus infection and endemic Burkitt's lymphoma.

  2020cites this paper
• Predictors of Epstein-Barr virus serostatus and implications for vaccine policy: A systematic review of the literature

  2020cites this paper
• CD21 (Complement Receptor 2) Is the Receptor for Epstein-Barr Virus Entry into T Cells

  2020cites this paper
• A New Hope for CD56negCD16pos NK Cells as Unconventional Cytotoxic Mediators: An Adaptation to Chronic Diseases

  2020cites this paper
• LSHTM Research Online

  2020cites this paper
• Maternal Epstein-Barr virus-specific antibodies and risk of infection in Ugandan infants.

  2020cites this paper
• Malaria during pregnancy and transplacental transfer of Kaposi sarcoma-associated herpesvirus (KSHV) antibodies: a cohort study of Kenyan mother and child pairs

  2020cites this paper
• Malaria is associated with Kaposi sarcoma-associated herpesvirus (KSHV) seroconversion in a cohort of western Kenyan children.

  2020cites this paper
• Cytomegalovirus infection is a risk factor for TB disease in 1 Infants 2

  2019cites this paper
• The Role of the Human Virome in Hematologic Malignancies

  2019cites this paper
• Childhood and Adolescence Non-Hodgkin Lymphomas in Low- and Middle-Income Countries

  2019cites this paper
• An etiological role for the Epstein-Barr virus in the pathogenesis of classical Hodgkin lymphoma.

  2019cites this paper
• Plasma Epstein-Barr Virus Load as an Early Biomarker and Prognostic Factor of Human Immunodeficiency Virus–related Lymphomas

  2019cites this paper
• Current Understanding of Innate Immune Cell Dysfunction in Childhood Undernutrition

  2019cites this paper
• Determinants of-herpesvirus shedding in saliva among Ugandan children and their mothers

  2019cites this paper
• The Association between the Comprehensive Epstein–Barr Virus Serologic Profile and Endemic Burkitt Lymphoma

  2019cites this paper
• Predictors of Epstein-Barr virus serostatus in young people in England

  2019cites this paper
• HIV, Cytomegalovirus, and Malaria Infections during Pregnancy Lead to Inflammation and Shifts in Memory B Cell Subsets in Kenyan Neonates

  2019cites this paper
• Determinants of Kaposi's sarcoma-associated herpesvirus seropositivity, viral DNA detection and cellular immune responses in Uganda

  2019cites this paper
• Interaction between maternally derived antibodies and heterogeneity in exposure combined to determine time-to-first Plasmodium falciparum infection in Kenyan infants

  2019cites this paper
• Epstein‐Barr virus associated smooth muscle tumors in solid organ transplant recipients: Incidence over 31 years at a single institution and review of the literature

  2018cites this paper
• Poorly cytotoxic terminally differentiated CD56negCD16pos NK cells accumulate in Kenyan children with Burkitt lymphomas.

  2018cites this paper
• Age of Infection with Kaposi Sarcoma–Associated Herpesvirus and Subsequent Antibody Values Among Children in Uganda

  2018cites this paper
• Primary Epstein-Barr virus infection.

  2018cites this paper
• Epstein-Barr Virus DNA in Parental Oral Secretions: A Potential Source of Infection for Their Young Children

  2018cites this paper
• Changes in Tonsil B Cell Phenotypes and EBV Receptor Expression in Children Under 5‐Years‐Old

  2018cites this paper
• A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection

  2018cites this paper
• Determinants of Gammaherpesvirus Shedding in Saliva Among Ugandan Children and Their Mothers

  2018cites this paper
• Differences in the Epstein-Barr Virus gp350 IgA Antibody Response Are Associated With Increased Risk for Coinfection With a Second Strain of Epstein-Barr Virus

  2018cites this paper
• Assessment of the Combined Effect of Epstein–Barr Virus and Plasmodium falciparum Infections on Endemic Burkitt Lymphoma Using a Multiplex Serological Approach

  2017cites this paper
• High pathogen burden in childhood promotes the development of unconventional innate-like CD8+ T cells.

  2017influential citation
• Cancer risks in Nairobi (2000–2014) by ethnic group

  2017cites this paper
• Transient reduction in IgA+ and IgG+ memory B cell numbers in young EBV‐seropositive children: the Generation R Study

  2017cites this paper
• Correlation Between Epstein-Barr Virus Infection and The Severity of Malaria in Ghanaian Children Under Five (5) Years of Age

  2017cites this paper
• The role of the early social environment on Epstein Barr virus infection: a prospective observational design using the Millennium Cohort Study

  2017cites this paper
• Cytomegalovirus infection is a risk factor for TB disease in Infants

  2017cites this paper
• Epstein-Barr Virus Type 2 Infects T Cells in Healthy Kenyan Children

  2017cites this paper
• Epidemiology of Hematologic Malignancies

  2017cites this paper
• Viral driven epigenetic events alter the expression of cancer-related genes in Epstein-Barr-virus naturally infected Burkitt lymphoma cell lines

  2017cites this paper
• Whole-genome association study of antibody response to Epstein-Barr virus in an African population: a pilot

  2017cites this paper