Export Requirements of Pneumolysin in Streptococcus pneumoniae

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Bacteriology

• Publication date

  2012-05-04

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JB.00114-12PMID 22563048PMCID PMC3393478
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Surface Export of GAPDH/SDH, a Glycolytic Enzyme, Is Essential for Streptococcus pyogenes Virulence

  2011influential reference
• Pneumolysin Localizes to the Cell Wall of Streptococcus pneumoniae

  2009cited by this paper
• Pneumolysin Causes Neuronal Cell Death through Mitochondrial Damage

  2007cited by this paper
• Expression of Yeast Mitochondrial Aconitase in Bacillus subtilis

  2006cited by this paper
• RrgA and RrgB Are Components of a Multisubunit Pilus Encoded by the Streptococcus pneumoniae rlrA Pathogenicity Islet

  2006cited by this paper
• Structural basis of pore formation by the bacterial toxin pneumolysin.

  2005cited by this paper
• Vertical collapse of a cytolysin prepore moves its transmembrane β‐hairpins to the membrane

  2004cited by this paper
• PSORT-B: improving protein subcellular localization prediction for Gram-negative bacteria

  2003cited by this paper
• Transcriptional Regulation in the Streptococcus pneumoniae rlrA Pathogenicity Islet by RlrA

  2003cited by this paper
• Estimates of world-wide distribution of child deaths from acute respiratory infections.

  2002cited by this paper
• Large‐scale identification of serotype 4 Streptococcus pneumoniae virulence factors

  2002cited by this paper
• α‐Enolase of Streptococcus pneumoniae is a plasmin(ogen)‐binding protein displayed on the bacterial cell surface

  2001cited by this paper
• The Autolytic Enzyme LytA of Streptococcus pneumoniae Is Not Responsible for Releasing Pneumolysin

  2001cited by this paper
• Pneumococcal Virulence Factors: Structure and Function

  2001cited by this paper
• Cross‐regulation of competence pheromone production and export in the early control of transformation in Streptococcus pneumoniae

  2000cited by this paper
• The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion.

  1999cited by this paper
• Pneumolysin, a Protein Toxin of Streptococcus pneumoniae, Induces Nitric Oxide Production from Macrophages

  1999cited by this paper
• The molecular mechanism of pneumolysin, a virulence factor from Streptococcus pneumoniae.

  1998cited by this paper
• α-Enolase, a Novel Strong Plasmin(ogen) Binding Protein on the Surface of Pathogenic Streptococci*

  1998cited by this paper
• Differences in virulence for mice among Streptococcus pneumoniae strains of capsular types 2, 3, 4, 5, and 6 are not attributable to differences in pneumolysin production

  1997cited by this paper
• Molecular analysis of the pathogenicity of Streptococcus pneumoniae: the role of pneumococcal proteins.

  1993cited by this paper
• Regulation of the phosphorelay and the initiation of sporulation in Bacillus subtilis.

  1993cited by this paper
• A major surface protein on group A streptococci is a glyceraldehyde-3- phosphate-dehydrogenase with multiple binding activity

  1992influential reference
• Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute‐phase protein

  1991cited by this paper
• Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension.

  1989cited by this paper
• Epidemiology of otitis media in infants and preschool children

  1989cited by this paper
• The impact of otitis media

  1989cited by this paper
• Nucleotide sequence of the gene for perfringolysin O (theta-toxin) from Clostridium perfringens: significant homology with the genes for streptolysin O and pneumolysin

  1988cited by this paper
• Molecular cloning, characterization, and complete nucleotide sequence of the gene for pneumolysin, the sulfhydryl-activated toxin of Streptococcus pneumoniae

  1987influential reference
• Activation of human complement by the pneumococcal toxin pneumolysin

  1984cited by this paper
• Escherichia coli mutants accumulating the precursor of a secreted protein in the cytoplasm

  1979cited by this paper
• Use of gene fusion to study secretion of maltose-binding protein into Escherichia coli periplasm

  1979cited by this paper
• Cellular location of pneumolysin

  1977cited by this paper
• Fate of transforming DNA following uptake by competent Bacillus subtilis

  1973cited by this paper
• Fate of transforming DNA following uptake by competent Bacillus subtilis. Formation and properties of products isolated from transformed cells which are derived entirely from donor DNA.

  1972cited by this paper
• Fate of transforming DNA following uptake by competent Bacillus subtilis. I. Formation and properties of the donor-recipient complex.

  1971cited by this paper

• Structure, Function, and Regulation of LytA: The N-Acetylmuramoyl-l-alanine Amidase Driving the “Suicidal Tendencies” of Streptococcus pneumoniae—A Review

  2025cites this paper
• Structural analysis of extracellular ATP-independent chaperones of streptococcal species and protein substrate interactions

  2025cites this paper
• Pneumococcal pneumonia is driven by increased bacterial turnover due to bacteriocin-mediated intra-strain competition

  2024cites this paper
• Blood–Brain Barrier Integrity Damage in Bacterial Meningitis: The Underlying Link, Mechanisms, and Therapeutic Targets

  2023cites this paper
• The Global Burden of Community-Acquired Pneumonia in Adults, Encompassing Invasive Pneumococcal Disease and the Prevalence of Its Associated Cardiovascular Events, with a Focus on Pneumolysin and Macrolide Antibiotics in Pathogenesis and Therapy

  2023cites this paper
• The Yin and Yang of Pneumolysin During Pneumococcal Infection

  2022cites this paper
• Oxidative Reactions Catalyzed by Hydrogen Peroxide Produced by Streptococcus pneumoniae and Other Streptococci Cause the Release and Degradation of Heme from Hemoglobin

  2022cites this paper
• Diversity of β‐hemolysins produced by the human opportunistic streptococci

  2021cites this paper
• Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin

  2020cites this paper
• Streptococcus pneumoniae is a Gram-positive pathogen with high morbidity and mortality globally but some of its patho-

  2020cites this paper
• Streptococcus pneumoniae aminopeptidase N contributes to bacterial virulence and elicits a strong innate immune response through MAPK and PI3K/AKT signaling

  2020cites this paper
• Macrophage LC3-associated phagocytosis is an immune defense against Streptococcus pneumoniae that diminishes with host aging

  2020cites this paper
• Soluja tappavan pneumolysiini-toksiinin tuhovaikutuksen estäminen polyfenoleilla

  2020cites this paper
• Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity

  2020cites this paper
• Hydrogen Peroxide Production by Streptococcus pneumoniae Results in Alpha-hemolysis by Oxidation of Oxy-hemoglobin to Met-hemoglobin

  2020cites this paper
• Pneumolysin: Pathogenesis and Therapeutic Target

  2020cites this paper
• Streptococcus pneumoniae: Invasion and Inflammation

  2019cites this paper
• Pneumolysin Induces 12-Lipoxygenase–Dependent Neutrophil Migration during Streptococcus pneumoniae Infection

  2019cites this paper
• The role of pneumolysin sequence variants and strain background in the virulence Of Streptococcus pneumoniae

  2019cites this paper
• Listeriolysin O: A phagosome‐specific cytolysin revisited

  2019cites this paper
• YesU from Bacillus subtilis preferentially binds fucosylated glycans

  2018cites this paper
• Gamma-irradiation-killed Streptococcus pneumoniae potently induces the expression of IL-6 and IL-8 in human bronchial epithelial cells.

  2018cites this paper
• Blood‒Brain Barrier Pathology and CNS Outcomes in Streptococcus pneumoniae Meningitis

  2018cites this paper
• Pneumolysin as a vaccine and study of structure and function

  2017cites this paper
• Streptococcus pneumoniae‐induced ototoxicity in organ of Corti explant cultures

  2017cites this paper
• The accessory Sec system (SecY2A2) in Streptococcus pneumoniae is involved in export of pneumolysin toxin, adhesion and biofilm formation

  2017cites this paper
• Host-to-Host Transmission of Streptococcus pneumoniae Is Driven by Its Inflammatory Toxin, Pneumolysin.

  2017cites this paper
• Streptococcus pneumoniae and lytic antibiotic therapy: are we adding insult to injury during invasive pneumococcal disease and sepsis?

  2017cites this paper
• hBD-2 and hBD-3 are induced in S. pneumoniae infected human macrophages via distinct signaling pathways but exhibit similar immune modulatory functions

  2016cites this paper
• Pyruvate oxidase of Streptococcus pneumoniae contributes to pneumolysin release

  2016cites this paper
• Streptococcus pneumoniae Cell-Wall-Localized Phosphoenolpyruvate Protein Phosphotransferase Can Function as an Adhesin: Identification of Its Host Target Molecules and Evaluation of Its Potential as a Vaccine

  2016cites this paper
• Perfringolysin O and related cholesterol-dependent cytolysins: Mechanism of pore formation

  2015cites this paper
• Peptidoglycan Branched Stem Peptides Contribute to Streptococcus pneumoniae Virulence by Inhibiting Pneumolysin Release

  2015influential citation
• Streptococcal toxins: role in pathogenesis and disease

  2015influential citation
• The Unique Molecular Choreography of Giant Pore Formation by the Cholesterol-Dependent Cytolysins of Gram-Positive Bacteria.

  2015cites this paper
• Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+ Efflux

  2015cites this paper
• Chapter 14 – Pneumolysin

  2015cites this paper
• Genomics, Genetic Variation, and Regions of Differences

  2015cites this paper
• CHARACTERIZATION OF VIRULENCE IN CLINICAL ISOLATES OF STREPTOCOCCUS PNEUMONIAE

  2015cites this paper
• Microreview Streptococcal toxins : role in pathogenesis and disease

  2015cites this paper
• Vaccine Potential of Pneumococcal Proteins

  2015cites this paper
• Understanding the Dynamics and Spread of Pneumococcal Infection From Healthy Carriage to Pneumonia and Invasive Disease, in Kilifi, Kenya

  2015cites this paper
• The biology of pneumolysin.

  2014cites this paper
• Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae.

  2014cites this paper
• Mouse, but Not Human, ApoB-100 Lipoprotein Cholesterol Is a Potent Innate Inhibitor of Streptococcus pneumoniae Pneumolysin

  2014cites this paper
• Development of Pneumolysin as a vaccine candidate

  2014cites this paper
• Review: current and new generation pneumococcal vaccines.

  2014cites this paper
• Stress response and pathogenicity in Streptococcus pneumoniae

  2014influential citation
• Human Antibodies to PhtD, PcpA, and Ply Reduce Adherence to Human Lung Epithelial Cells and Murine Nasopharyngeal Colonization by Streptococcus pneumoniae

  2014cites this paper
• Aus der Medizinischen Klinik mit Schwerpunkt Infektiologie und Pneumologie der Medizinischen Fakultät Charité - Universitätsmedizin Berlin

  2014cites this paper
• The molecular basis of adjuvant activity of pneumolysin

  2014cites this paper
• The diversity of receptor recognition in cholesterol‐dependent cytolysins

  2014cites this paper
• Novel Role for the Streptococcus pneumoniae Toxin Pneumolysin in the Assembly of Biofilms

  2013cites this paper
• Molecular characterisation of the polyhistidine triad proteins of Streptococcus pneumoniae.

  2013cites this paper
• Infectious Diseases Role of Pore-Forming Toxins in Bacterial

  2013cites this paper
• Surface Association of Pht Proteins of Streptococcus pneumoniae

  2013cites this paper
• Role of Pore-Forming Toxins in Bacterial Infectious Diseases

  2013cites this paper
• Characterization of Protective Immune Responses Induced by Pneumococcal Surface Protein A in Fusion with Pneumolysin Derivatives

  2013cites this paper
• Current concepts in host–microbe interaction leading to pneumococcal pneumonia

  2013cites this paper
• Efflux + Is Dependent on K and Inflammasome and Caspase-1 Activation Nlrp3/asc Pneumolysin Is Mediated by the Processing Induced by Β Neutrophil Il-1

  year unknowncites this paper
• Pneumolysin in the Assembly of Biofilms Toxin Streptococcus pneumoniae Novel Role for the 2013

  year unknowncites this paper